The main objective of this study was to identify advantages, prospects, and drivers of and challenges from plant molecular farming (PM farming) with a particular focus on the EU. The report, considers techno-economic, regulatory and wider policy aspects including stakeholder and public perception. It covers PM farming for producing biopharmaceuticals and vaccines, subsequently referred to as plant-made pharmaceuticals (PMPs) and plant-made vaccines (PMVs), and for plant-made industrials (PMIs) intended to be used for food and feed purposes (food supplements, food and feed additives). The study is based on literature reviews, document analysis and interviews.