Objective
Background :
Contagious Bovine Pleuropneumonia (CBPP) is a severe respiratory disease of cattle
which causes high economic damage and has persisted in Europe for a long time. CBPP is caused by Mycoplasma mycoides subsp, mycoides sc variant and it is thought to be endemic in some areas of the Iberian peninsula and recent outbreaks have occurred in other European countries (France, Italy). The available serological diagnostic tests have a limited efficiency.
The objective of this project is to develop and evaluate new and improved tests for the isolation, identification and differentiation of the causative agent, through: i) the
development of a high quality antigen; ii) the development of new enzyme immunoassays based on monoclonal antibodies; iii) the evaluation of intradermal and gamma interferon tests for cell-mediated immunity; and, iv) the development of polymerase chain reactions tests.
Short description of the project :
The project will consist of the following tasks:
- Improvement and standardization of the complement fixation test for CBPP;
- Improvement of the media for transport and isolation of M. m mycoides SC;
- Improvement of the biochemical identification of M. m mycoides SC;
- Development of improved serological tests;
- Development of tests for cell mediated immunity;
- Development and improvement of polymerase chain reaction systems for the
detection of M. m mycoides SC;
- Development of molecular diagnostic systems based on 16S ribosomal transfer
RNA analysis;
- Evaluation of tests in experimentally and naturally infected cattle.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- medical and health sciences health sciences infectious diseases RNA viruses coronaviruses
- natural sciences biological sciences genetics RNA
- agricultural sciences animal and dairy science domestic animals animal husbandry
- natural sciences biological sciences biochemistry biomolecules proteins enzymes
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Programme(s)
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Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
64100 Teramo
Italy
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.