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Cytogenetic experiments failed to detect clear evidence for a negative bystander response in human lymphocytes cultured with irradiated cells
Irradiated Go lymphocytes were fused to exponentially growing CHO cells and cultured for up to 30h. In the hybrid cells, lymphocyte PCCs were induced when CHO entered mitosis. Cells were harvested at various times after cell fusion using shake off and subsequently chromosome p...
Programme: FP5-EAECTP C
Record Number: 44729
Last updated on: 2007-12-12
Voraussetzungen für den Bystander-Effekt
Die Wirkung von Strahlung ist nicht nur auf die direkt bestrahlten Zellen begrenzt. Forscher untersuchten den so genannten Bystander-Effekt und dessen Bedeutung für den Strahlenschutz und die Strahlentherapie.
Programme: FP5-EAECTP C
Record Number: 84786
Last updated on: 2009-02-09
Available languages: DE, EN, ES, FR, IT, PL
Circumstances necessary for the bystander effect
The consequences of radiation are not always limited to the cells directly under bombardment. Researchers have investigated this so-called bystander effect in order to determine its relevance in both radiation protection and therapy.
Programme: FP5-EAECTP C
Record Number: 84786
Last updated on: 2009-02-09
Available languages: DE, EN, ES, FR, IT, PL
No negative bystander effects were observed for human cells (HSF) exposed to either 4.5MeV alpha particles or 10MeV protons using a microbeam
In order to study the parameter of LET and cell type on the development of bystander effects using cell survival as endpoint, we carried out experiments with primary human skin fibroblasts (HSF2). Using 4.5MeV alpha particles (LET = 100keV/µm) we were unable to measure bystand...
Programme: FP5-EAECTP C
Record Number: 44728
Last updated on: 2007-12-12
Les conditions nécessaires à l'effet de proximité
Les conséquences de l'irradiation ne sont pas toujours limitées aux cellules directement ciblées par les bombardements ionisants. Les chercheurs ont étudié ce phénomène connu sous le nom d'effet de proximité (ou «bystander effect») afin de déterminer son importance à la fois d...
Programme: FP5-EAECTP C
Record Number: 84786
Last updated on: 2009-02-09
Available languages: DE, EN, ES, FR, IT, PL
Circunstancias necesarias para que se produzca el efecto espectador
Las consecuencias de la radiación no siempre se limitan a las células a las que el bombardeo alcanza directamente. Un grupo de investigadores de un proyecto comunitario ha investigado el llamado «efecto espectador» a fin de determinar su importancia tanto en la protección cont...
Programme: FP5-EAECTP C
Record Number: 84786
Last updated on: 2009-02-09
Available languages: DE, EN, ES, FR, IT, PL
Circostanze necessarie per l'effetto bystander
Le conseguenze delle radiazioni non si limitano sempre alle cellule direttamente bombardate. I ricercatori hanno studiato il cosiddetto effetto bystander per determinarne l'importanza nella radioprotezione e nella radioterapia.
Programme: FP5-EAECTP C
Record Number: 84786
Last updated on: 2009-02-09
Available languages: DE, EN, ES, FR, IT, PL
Okoliczności niezbędne dla wystąpienia efektu sąsiedztwa
Konsekwencje promieniowania nie zawsze są ograniczone do komórek bezpośrednio nim bombardowanych. Naukowcy zbadali tak zwany efekt sąsiedztwa, aby określić jego zastosowanie w ochronie przed promieniowaniem, jak i w terapii.
Programme: FP5-EAECTP C
Record Number: 84786
Last updated on: 2013-05-17
Available languages: DE, EN, ES, FR, IT, PL
The role of intercellular communication and DNA double strand breaks in the induction of bystander effects
ID: FIGH-CT-2002-00218
Start date: 2003-03-01, End date: 2006-03-01
The biological processes mediating bystander responses are incompletely understood despite the relevance of this phenomenon to radiation protection and radiation therapy. The present proposal contributes to the elucidation of the mechanisms underlying bystander effects by eval...
Programme: FP5-EAECTP C
Record Number: 69008
Last updated on: 2003-04-01
Einfacher und schneller Zugang zu Experimenten mit Radionukliden
Experten, die an der Entwicklung von Normen und Richtlinien bezüglich des Umgangs mit radioaktiven Materialien arbeiten, können von der Schaffung einer verbesserten Datenbank profitieren, in der Informationen von über 1.900 Experimenten zu diesem Thema gespeichert sind.
Programme: FP5-EAECTP C
Record Number: 84622
Last updated on: 2008-12-05
Available languages: DE, EN, ES, FR, IT, PL
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List retrieved on: 2018-01-20
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