Objective The scientific objectives include achievement of quantitative spectroscopy by developing an advanced European Near Infrared Spectroscopy instrument, designed to meet the requirements of the clinicians. and improve and validate image reconstruction algorithms and improve data acquisition techniques as a first step towards neonatal brain functional imaging.The current CA programme will terminate on 31 December 1995 after establishing a solid base for a shared cost programme. This proposal for the Biomed 2 programme for the period Jan 96 to June 97 has a number of clearly defined objectives. One of the key objectives is the achievement of quantitative spectroscopy by developing an advanced European near infrared spectroscopy instrument. The objectives also include methods and techniques to improve and expand the accuracy of NIRS data and will include determinations of absorption and scattering properties of tissue. Measurement of CBV and CBF will be further refined and spatial localisation available from NIRS will be assessed. Muscle function will be evaluated by combining NIRS and MRS.The FEM models developed during the existing CA programme show good agreement but in order to guarantee a satisfactory behaviour in clinical applications the FEM model has to be validated against experimental data. Both the forward and inverse (reconstruction) models will be validated. The data acquisition time from phantoms as well as from biological tissue needs to be substantially reduced, for functional imaging and an automated data collection system will be developed. In parallel with this work tissue equivalent imaging phantoms representative of the neonatal brain and breast will be developed. Fields of science natural sciencesphysical sciencesopticsspectroscopyabsorption spectroscopy Programme(s) FP4-BIOMED 2 - Specific research, technological development and demonstration programme in the field of biomedicine and health, 1994-1998 Topic(s) 2.2 - Imaging systems and other devices for diagnosis and therapy Call for proposal Data not available Funding Scheme CSC - Cost-sharing contracts Coordinator University of Keele EU contribution No data Address Thornburrow Drive ST4 7QB Stoke on Trent United Kingdom See on map Total cost No data Participants (8) Sort alphabetically Sort by EU Contribution Expand all Collapse all Ecole Polytechnique Fédérale de Lausanne Switzerland EU contribution No data Address 1015 Lausanne See on map Total cost No data Katholieke Universiteit Nijmegen Netherlands EU contribution No data Address 21,Geert Grooteplein 6525 EZ Nijmegen See on map Total cost No data Krbenhavns Universitet Denmark EU contribution No data Address 9,Blegdamsvej 2100 Krbenhavn Ø See on map Total cost No data UNIVERSITÀ DEGLI STUDI - L'AQUILA Italy EU contribution No data Address Via Vetoio 67010 ASSERGI See on map Total cost No data Birkbeck College, University of London United Kingdom EU contribution No data Address Malet Street, Bloomsbury WC1E 7HX London See on map Total cost No data University of Nottingham United Kingdom EU contribution No data Address University Park NG7 2RD Nottingham See on map Total cost No data Università degli Studi di Firenze Italy EU contribution No data Address Via Santa Marta 3 50139 Firenze See on map Total cost No data Universität Zürich Switzerland EU contribution No data Address 10,Frauenklinikstrasse 10 8091 Zürich See on map Total cost No data
