Objective The aim of the SOUL project is to quantify risks of late health effects associated with low-dose rate exposure to plutonium, strontium and external gamma radiation. This will be done by improving, updating and analysing dosimetric and health data for the Mayak worker cohort (MWC), the extended Techa River cohort (ETRC) and the Techa River offspring cohort (TROC). Key dosimetric elements include electron paramagnetic resonance (EPR) measurements of tooth enamel, photon spectra measurements, luminescence measurements of absorbed doses in bricks, measurements of strontium distributions in teeth, fluorescence in-situ hybridisation (FISH) measurements of chromosome aberrations, and modelling of internal doses of foetuses and infants. The dosimetric work aims to produce updated dose data bases Mayak Doses 2008 and Techa Doses 2008. In order to increase statistical precision and validity, the number of individuals in the cohorts will be extended, and information on vital status and cause of death will be updated. In the TROC, cancer and cardiovascular disorders will be studied as late health effects following exposure early in life. Non-cancer effects will be studied in the ETRC. The pathogenesis of lung cancer in the MWC will be studied in order to improve the current knowledge. The MWC will be used to study cancer incidence, and mortality and morbidity of circulatory diseases such as myocardial infarction and stroke. In the studies, initial feasibility analyses will be followed - if affirmative - by analyses that are based on longer follow-up and dosimetric data bases improved within the framework of SOUL. Although SOUL is expected to give significant input to the understanding of radiation risks, Southern Urals radiation risk research has to be tinued beyond the project mainly because a longer follow-up is needed to fully quantify lifetime risks. Part of the work in SOUL is dedicated to supporting such future analyses. Fields of science medical and health sciencesclinical medicineoncologylung cancermedical and health sciencesclinical medicinecardiologycardiovascular diseasesnatural scienceschemical sciencesnuclear chemistryradiation chemistry Programme(s) FP6-EURATOM-RADPROT - Thematic priority - Radiation Protection as part of the specific framework programme for the European Atomic Energy Community, within the multi-annual framework programme 2002-2006. Topic(s) RAD PROT-2004- 3.3.1.1.-1 - Epidemiological studies of exposed populations in the Southern Urals Call for proposal EURATOMCALL2004-FIXEDDEADLINE See other projects for this call Funding Scheme IP - Integrated Project Coordinator HELMHOLTZ ZENTRUM MUENCHEN, DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT EU contribution No data Address lngolstaedter Landstrasse 1 NEUHERBERG Germany See on map Links Website Opens in new window Total cost No data Participants (15) Sort alphabetically Sort by EU Contribution Expand all Collapse all HEALTH PROTECTION AGENCY United Kingdom EU contribution No data Address 330 High Holborn - Holborn Gate - 7th Floor LONDON See on map Links Website Opens in new window Total cost No data URALSKY NAUCHNO-PRAKTICHESKY TSENTR RADIATSIONNOI MEDITSINY Russia EU contribution No data Address Vorovsky street 68A CHELYABINSK See on map Links Website Opens in new window Total cost No data SOUTHERN URALS BIOPHYSICS INSTITUTE Russia EU contribution No data Address Ozyorskoye shosse 19 OZYORSK See on map Total cost No data KAROLINSKA INSTITUTET Sweden EU contribution No data Address Nobels vaeg 1 STOCKHOLM See on map Links Website Opens in new window Total cost No data GEOSPETZECOLOGIYA Russia EU contribution No data Address Lenin avenue 6 - Building 2 MOSCOW See on map Total cost No data ISTITUTO SUPERIORE DI SANITA Italy EU contribution No data Address Viale Regina Elena 299 ROMA See on map Links Website Opens in new window Total cost No data BUNDESAMT FUER STRAHLENSCHUTZ Germany EU contribution No data Address Willy-Brandt-Strasse 5 10149 SALZGITTER See on map Links Website Opens in new window Total cost No data ARISTOTELIO PANEPISTIMIO THESSALONIKIS Greece EU contribution No data Address Administration Building - University Campus THESSALONIKI See on map Links Website Opens in new window Total cost No data AKADEMISCH ZIEKENHUIS LEIDEN Netherlands EU contribution No data Address Albinusdreef 2 LEIDEN See on map Total cost No data WESTLAKES SCIENTIFIC CONSULTING LIMITED United Kingdom EU contribution No data Address Westlakes Science and Technology Park MOOR ROW / CUMBRIA See on map Links Website Opens in new window Total cost No data TECHNISCHE UNIVERSITAET MUENCHEN Germany EU contribution No data Address Arcisstrasse 21 MUENCHEN See on map Total cost No data INSTITUTE OF METAL PHYSICS, RUSSIAN ACADEMY OF SCIENCES Russia EU contribution No data Address Sofia Kovalevskaya St. 18 YEKATERINBURG See on map Total cost No data UNIVERSITA DEGLI STUDI DI PALERMO Italy EU contribution No data Address PIAZZA MARINA 61 PALERMO See on map Links Website Opens in new window Total cost No data UNIVERSITY OF FLORIDA United States EU contribution No data Address University Avenue 116550 GAINESVILLE See on map Total cost No data EBERHARD KARLS UNIVERSITAET TUEBINGEN Germany EU contribution No data Address Wilhelmstrasse 7 TUEBINGEN See on map Links Website Opens in new window Total cost No data
