Objective Behavioural change is the most sensitive biological end-point signalling any alteration in the organism of a mouse. However, large-scale bio-assays of behaviour face limitations: outdated technology, need for space and specialized manpower, lack of standardisation, and increasing legal demands on animal husbandry. This has limited the use of behavioural methods to specialised laboratories, limiting the market as well. In order to advance scientific progress and expand the market, 2 SME's and 1 academic partner will combine their existing expertise and products for behavioural phenotyping to generate a compact modular system, INTELLIMAZE. This system should fit into a single small mouse room, where it will - Assess home cage activity and learning of transponder-tagged mice living in social groups - Analyse automatically social behaviour - Guide individual mice to a battery of traditionally used tests - Show ongoing learning on-line to a supervisor working in his office - Analyse data according to expert knowledge-based rules - Provide a web-based analysis of results for user groups. The bottleneck of such technological development is functional validation and comparison with traditional tests. Three academic partners will use the novel technology for a) generating new mouse models of depression, b) profiling malfunctions of specific brain systems, and c) monitoring the effects of age-dependent neurodegeneration in existing and new mouse models. Finally, an SME partner in need of efficient behavioural phenotyping will validate the novel systems for drug discovery and development. We expect that the availability of simplified, rapid and thorough behavioural testing of mice without need for specialized personnel will open new and larger markets for the SME's. Moreover we predict significant scientific discoveries in the fields of drug development, psychopharmacology, neurodegeneration, neural plasticity and repair, and genetic engineering. Fields of science medical and health sciencesbasic medicinepharmacology and pharmacydrug discoverymedical and health sciencesmedical biotechnologygenetic engineeringmedical and health sciencesbasic medicinephysiologyagricultural sciencesanimal and dairy sciencedomestic animalsanimal husbandrymedical and health sciencesclinical medicinepsychiatryschizophrenia Programme(s) FP6-LIFESCIHEALTH - Life sciences, genomics and biotechnology for health: Thematic Priority 1 under the Focusing and Integrating Community Research programme 2002-2006. Topic(s) LSH-2005-2.1.3-6 - Neuroscience-oriented new technologies LSH-2005-2.1.3-7 - Characterisation and use of animal models for neurological and psychiatric diseases IST - Information society technologies Call for proposal FP6-2005-LIFESCIHEALTH-7 See other projects for this call Funding Scheme STREP - Specific Targeted Research Project Coordinator NEWbehaviour AG EU contribution No data Address Quellenstrasse 31 ZÜRICH Switzerland See on map Links Website Opens in new window Total cost No data Participants (6) Sort alphabetically Sort by EU Contribution Expand all Collapse all FBI SCIENCE GMBH Germany EU contribution No data Address Kruppstrasse 82-100 ESSEN See on map Links Website Opens in new window Total cost No data ISTITUTO SUPERIORE DI SANITÀ Italy EU contribution No data Address Viale Regina Elena 299 ROMA See on map Links Website Opens in new window Total cost No data KAROLINSKA INSTITUTET Sweden EU contribution No data Address Nobels väg 5 STOCKHOLM See on map Links Website Opens in new window Total cost No data UNIVERSITÄT ZÜRICH Switzerland EU contribution No data Address Rämistrasse 71 ZÜRICH See on map Links Website Opens in new window Total cost No data P.K.ANOKHIN INSTITUTE OF NORMAL PHYSIOLOGY, RUSSIAN ACADEMY OF MEDICAL SCIENCE Russia EU contribution No data Address Mokhovaya str. 11 bd. 4 MOSCOW See on map Links Website Opens in new window Total cost No data EVOTEC NEUROSCIENCES GMBH Germany EU contribution No data Address Schnackenburgallee 144 HAMBURG See on map Links Website Opens in new window Total cost No data
