Résultats exploitables Genetic modification of parvovirus Modification of the genomes of parvoviruses H-1 and MVM, attempting to make them suitable linear vectors, has resulted in: production of recombinant parvoviruses showing transduction specificity for oncogene-transformed cells and having potential for cancer gene therapy; programmed cell killing by means of inducible clones of parvoviral genes encoding nonstructural proteins; demonstration and unravelling of the oncolytic activity of parvoviruses, raising prospects of anticancer applications. Recherche de données OpenAIRE... Une erreur s’est produite lors de la recherche de données OpenAIRE Aucun résultat disponible
