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Generation of Drosophila enhancer-trap lines expressing a GAL4 transcriptional activator and their use in the study of Drosophila neurobiology

Ziel



Enhancer-trapping in the fruitfly Drosophila is a versatile
approach for generation of cell markers and isolation of developmentally regulated genes. A recent variant of the approach,
P-GAL4 enhancer-trapping, allows in principle the expression of any cloned gene in virtually any cell type. First, we will
generate several thousand P-GAL4 enhancer-trap fly lines and make them generally available to the Drosophila research community; this resource will be of particular use to the European fly
community. Second, we will use many of the lines generated for collaborative work in developmental neurobiology. At a later date, these enchancer-trap lines may also be of use for fly
genome mapping.

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CSC - Cost-sharing contracts

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University of Warwick
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CV4 7AL Coventry
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Letzte Aktualisierung: 3 September 1992

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Permalink: https://cordis.europa.eu/project/id/SC1*0790/de

European Union, 2024