What is Tuberculosis? Challenging the Current Paradigm of Tuberculosis Natural History using Mathematical Modelling Techniques

Informations projet

TBornotTB

N° de convention de subvention: 757699

DOI

10.3030/757699

Projet clôturé

Date de signature de la CE 12 Janvier 2018

Date de début 1 Mars 2018

Date de fin 30 Novembre 2023

Financé au titre de

• EXCELLENT SCIENCE - European Research Council (ERC)

Coût total

€ 1 499 818,75

Contribution de l’UE

€ 1 499 818,75

Coordonné par

LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE ROYAL CHARTER
United Kingdom

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Publications

Peer reviewed articles (23)

Asymptomatic but infectious – The silent driver of pathogen transmission. A pragmatic review

Auteurs: Nabila Shaikh; Pooja Swali; Rein M.G.J. Houben
Publié dans: Epidemics, 2023, ISSN 1755-4365
Éditeur: Elsevier BV
DOI: 10.1016/j.epidem.2023.100704

Subclinical tuberculosis disease - a review and analysis of prevalence surveys to inform definitions, burden, associations and screening methodology

Auteurs: Beatrice Frascella, Alexandra S Richards, Bianca Sossen, Jon C Emery, Anna Odone, Irwin Law, Ikushi Onozaki, Hanif Esmail, Rein M G J Houben
Publié dans: Clinical Infectious Diseases, 2020, ISSN 1058-4838
Éditeur: University of Chicago Press
DOI: 10.1093/cid/ciaa1402

Quantifying progression and regression across the spectrum of pulmonary tuberculosis: a data synthesis study

Auteurs: Alexandra S Richards, Bianca Sossen, Jon C Emery, Katherine C Horton, Torben Heinsohn, Beatrice Frascella, Federica Balzarini, Aurea Oradini-Alacreu, Brit Häcker, Anna Odone, Nicky McCreesh, Alison D Grant, Katharina Kranzer, Frank Cobelens, Hanif Esmail, Rein M G J Houben
Publié dans: The Lancet Global Health, 2023, ISSN 2214-109X
Éditeur: Elsevier BV
DOI: 10.1016/s2214-109x(23)00082-7

Classification of early tuberculosis states to guide research for improved care and prevention: an international Delphi consensus exercise

Auteurs: Anna K Coussens, Syed MA Zaidi, Brian A Allwood, Puneet K Dewan, Prof Glenda Gray, Mikashmi Kohli , Tamara Kredo, Prof Ben J Marais, Prof Guy Marks, Leo Martinez, Morten Ruhwald, Prof Thomas J Scriba, Prof James A Seddon, Phumeza Tisile, Prof Digby F Warner, Prof Robert J Wilkinson (PhD), Hanif Esmail (PhD), Rein MGJ Houben
Publié dans: The Lancet Respiratory Medicine, 2024, ISSN 2213-2600
Éditeur: Elsevier Limited
DOI: 10.1016/s2213-2600(24)00028-6

Adolescent tuberculosis

Auteurs: Kathryn J Snow, Andrea T Cruz, James A Seddon, Rashida A Ferrand, Silvia S Chiang, Jennifer A Hughes, Beate Kampmann, Steve M Graham, Peter J Dodd, Rein M Houben, Justin T Denholm, Susan M Sawyer, Katharina Kranzer
Publié dans: The Lancet Child & Adolescent Health, Numéro 4/1, 2020, Page(s) 68-79, ISSN 2352-4642
Éditeur: Elsevier
DOI: 10.1016/s2352-4642(19)30337-2

The natural history of untreated pulmonary tuberculosis in adults: a systematic review and meta-analysis

Auteurs: Bianca Sossen, Alexandra S Richards, Torben Heinsohn, Beatrice Frascella, Federica Balzarini, Aurea Oradini-Alacreu, Anna Odone, Ewelina Rogozinska, Brit Häcker, Frank Cobelens, Katharina Kranzer, Rein M G J Houben, Hanif Esmail
Publié dans: Lancet Respiratory Medicine, 2023, ISSN 2213-2600
Éditeur: Elsevier Limited
DOI: 10.1016/s2213-2600(23)00097-8

Reevaluating progression and pathways following <i>Mycobacterium tuberculosis</i> infection within the spectrum of tuberculosis

Auteurs: Katherine C. Horton; Alexandra S. Richards; Jon C. Emery; Hanif Esmail; Rein M. G. J. Houben
Publié dans: Proceedings of the National Academy of Sciences, 2023, ISSN 1091-6490
Éditeur: National Academy of Sciences
DOI: 10.1073/pnas.2221186120

Social determinants of the changing tuberculosis prevalence in Việt Nam: Analysis of population-level cross-sectional studies

Auteurs: Foster Nicola, Hai V. Nguyen, Nhung V. Nguyen, Hoa B. Nguyen, Edine W. Tiemersma, Frank G. J. Cobelens, Matthew Quaife, and Rein M. G. J. Houben.
Publié dans: PLOS Medicine, 2022, ISSN 1549-1676
Éditeur: PLOS
DOI: 10.1371/journal.pmed.1003935

Estimating the contribution of subclinical tuberculosis disease to transmission – an individual patient data analysis from prevalence surveys

Auteurs: Jon C. Emery; Peter J. Dodd; Sayera Banu; Beatrice Frascella; Frances L. Garden; Katherine C. Horton; Shahed Hossain; Irwin Law; Frank van Leth; Guy B. Marks; Hoa Binh Nguyen; Hai Viet Nguyen; Ikushi Onozaki; Maria Imelda D. Quelapio; Alexandra S Richards; Nabila Shaikh; Edine W. Tiemersma; Richard G White; Khalequ Zaman; Frank Cobelens; Rein MGJ Houben
Publié dans: Elife, 2023, ISSN 2050-084X
Éditeur: eLife Sciences Publications
DOI: 10.1101/2022.06.09.22276188

Treatment for radiographically active, sputum culture-negative pulmonary tuberculosis: a systematic review and meta-analysis

Auteurs: Adam Thorburn Gray; Liana Macpherson; Ffion Carlin; Bianca Sossen; Alexandra S. Richards; Sandra V. Kik; Rein M. G. J. Houben; Peter MacPherson; Matteo Quartagno; Ewelina Rogozińska; Hanif Esmail
Publié dans: PLOS ONE, 2023, ISSN 1932-6203
Éditeur: Public Library of Science
DOI: 10.1101/2023.01.27.23285085

The contribution of asymptomatic SARS-CoV-2 infections to transmission - a model-based analysis of the Diamond Princess outbreak

Auteurs: Emery, Jon C; Russel, Timothy W; Liu, Yang; Hellewell, Joel; Pearson, Carl AB; Knight, Gwen M; Eggo, Rosalind M; Kucharski, Adam J; Funk, Sebastian; Flasche, Stefan; Houben, Rein M G J
Publié dans: Elife, Numéro 4, 2020, ISSN 2050-084X
Éditeur: eLife Sciences Publications
DOI: 10.1101/2020.05.07.20093849

Self-clearance of Mycobacterium tuberculosis infection: implications for lifetime risk and population at-risk of tuberculosis disease.

Auteurs: Jon C Emery; Alexandra S Richards; Katie D Dale; C. Finn McQuaid; Richard G. White; Justin T Denholm; Rein M G J Houben
Publié dans: Proceedings. Biological Sciences, Numéro 2, 2021, ISSN 1471-2946
Éditeur: The Royal Society Publishing
DOI: 10.1098/rspb.2020.1635

Beyond latent and active – a scoping review of conceptual frameworks and diagnostic criteria for tuberculosis

Auteurs: Syed MA Zaidi; Anna K Coussens; James A Seddon; Tamara Kredo; Digby Warner; Rein M G J Houben; Hanif Esmail
Publié dans: eClinicalMedicine, Numéro 2, 2023, ISSN 2589-5370
Éditeur: Elsevier
DOI: 10.1101/2023.07.05.23292171

Contribution of remote M.tuberculosis infection to tuberculosis disease: A 30-year population study

Auteurs: Judith R. Glynn; Palwasha Khan; Themba Mzembe; Lifted Sichali; Paul E. M. Fine; Amelia C. Crampin; Rein M. G. J. Houben
Publié dans: PLOS ONE, 2023, ISSN 1932-6203
Éditeur: Public Library of Science
DOI: 10.1371/journal.pone.0278136

Mind the gap – Managing tuberculosis across the disease spectrum

Auteurs: Hanif Esmail; Liana Macpherson; Anna K. Coussens; Rein M.G.J. Houben
Publié dans: eBioMedicine, Numéro 2, 2022, ISSN 2352-3964
Éditeur: Elsevier BV
DOI: 10.1016/j.ebiom.2022.103928

Tuberculosis prevalence: beyond the tip of the iceberg

Auteurs: Houben, Rein M G J, Hanif Esmail, Frank Cobelens, Caroline M L Williams, and Anna K Coussens.
Publié dans: The Lancet Respiratory Medicine, 2022, ISSN 2213-2600
Éditeur: Elsevier Limited
DOI: 10.1016/s2213-2600(22)00184-9

The impact of social protection and poverty elimination on global tuberculosis incidence: a statistical modelling analysis of Sustainable Development Goal 1

Auteurs: Daniel J Carter; Philippe Glaziou; Knut Lönnroth; Andrew M. Siroka; Katherine Floyd; Diana Weil; Mario C. Raviglione; Mario C. Raviglione; Rein M G J Houben; Delia Boccia
Publié dans: The Lancet Global Health, Numéro 2, 2018, ISSN 2214-109X
Éditeur: Elsevier BV
DOI: 10.1016/s2214-109x(18)30195-5

Estimating Long-term Tuberculosis Reactivation Rates in Australian Migrants

Auteurs: Katie D Dale, James M Trauer, Peter J Dodd, Rein M G J Houben, Justin T Denholm
Publié dans: Clinical Infectious Diseases, 2019, ISSN 1058-4838
Éditeur: University of Chicago Press
DOI: 10.1093/cid/ciz569

What if They Don’t Have Tuberculosis? The Consequences and Trade-offs Involved in False-positive Diagnoses of Tuberculosis

Auteurs: Rein M G J Houben, Marek Lalli, Katharina Kranzer, Nick A Menzies, Samuel G Schumacher, David W Dowdy
Publié dans: Clinical Infectious Diseases, 2018, Page(s) 150-6, ISSN 1058-4838
Éditeur: University of Chicago Press
DOI: 10.1093/cid/ciy544

Systematic neglect of men as a key population in tuberculosis

Auteurs: Katherine C. Horton, Richard G. White, Rein M.G.J. Houben
Publié dans: Tuberculosis, Numéro 113, 2018, Page(s) 249-253, ISSN 1472-9792
Éditeur: Churchill Livingstone
DOI: 10.1016/j.tube.2018.09.006

Global burden of latent multidrug-resistant tuberculosis: trends and estimates based on mathematical modelling

Auteurs: Gwenan M Knight, C Finn McQuaid, Peter J Dodd, Rein M G J Houben
Publié dans: The Lancet Infectious Diseases, Numéro 19/8, 2019, Page(s) 903-912, ISSN 1473-3099
Éditeur: The Lancet Publishing Group
DOI: 10.1016/s1473-3099(19)30307-x

The Importance of Heterogeneity to the Epidemiology of Tuberculosis

Auteurs: James M Trauer, Peter J Dodd, M Gabriela M Gomes, Gabriela B Gomez, Rein M G J Houben, Emma S McBryde, Yayehirad A Melsew, Nicolas A Menzies, Nimalan Arinaminpathy, Sourya Shrestha, David W Dowdy
Publié dans: Clinical Infectious Diseases, Numéro 69/1, 2018, Page(s) 159-166, ISSN 1058-4838
Éditeur: University of Chicago Press
DOI: 10.1093/cid/ciy938

Use of chest radiography screening for TB: a re-evaluation of the Kolín study

Auteurs: Schwalb Calderon, Alvaro; Emery, J C; Houben, R M G J
Publié dans: The International Journal of Tuberculosis and Lung Disease, Numéro 2, 2022, ISSN 1027-3719
Éditeur: International Union Against Tuberculosis And Lung Disease/Union Internationale Contre la Tuberculose et les Maladies Respiratories
DOI: 10.5588/ijtld.22.0216

Non-peer reviewed articles (3)

Post-tuberculosis mortality and morbidity: valuing the hidden epidemic

Auteurs: Matthew Quaife, Rein M G J Houben, Brian Allwood, Ted Cohen, Anna K Coussens, Anthony D Harries, Sanne van Kampen, Florian M Marx, Sedona Sweeney, Robert S Wallis, Nicolas A Menzies
Publié dans: The Lancet Respiratory Medicine, Numéro 8/4, 2020, Page(s) 332-333, ISSN 2213-2600
Éditeur: Elsevier Limited
DOI: 10.1016/s2213-2600(20)30039-4

Tuberculosis transmission during the subclinical period: could unrelated cough play a part?

Auteurs: Hanif Esmail, Peter J Dodd, Rein M G J Houben
Publié dans: The Lancet Respiratory Medicine, Numéro 6/4, 2018, Page(s) 244-246, ISSN 2213-2600
Éditeur: Elsevier Limited
DOI: 10.1016/s2213-2600(18)30105-x

Spotting the old foe—revisiting the case definition for TB

Auteurs: Rein M G J Houben, Hanif Esmail, Jon C Emery, Louis R Joslyn, C Finn McQuaid, Nicolas A Menzies, Joaquín Sanz, Sourya Shrestha, Richard G White, Chongguang Yang, Frank Cobelens
Publié dans: The Lancet Respiratory Medicine, Numéro 7/3, 2019, Page(s) 199-201, ISSN 2213-2600
Éditeur: Elsevier Limited
DOI: 10.1016/s2213-2600(19)30038-4