Hybrid Enhanced Regenerative Medicine Systems

Informations projet

HERMES

N° de convention de subvention: 824164

DOI

10.3030/824164

Projet clôturé

Date de signature de la CE 12 Novembre 2018

Date de début 1 Janvier 2019

Date de fin 30 Septembre 2025

Financé au titre de

• EXCELLENT SCIENCE - Future and Emerging Technologies (FET)

Coût total

€ 8 429 857,50

Contribution de l’UE

€ 8 429 857,50

Coordonné par

FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA
Italy

CORDIS fournit des liens vers les livrables publics et les publications des projets HORIZON.

Les liens vers les livrables et les publications des projets du 7e PC, ainsi que les liens vers certains types de résultats spécifiques tels que les jeux de données et les logiciels, sont récupérés dynamiquement sur OpenAIRE .

Livrables

Documents, reports (5)

Developmental study of hippocampal organoid

Report on cellular and functional characterization of hippocampal organoid throughout its development.

Biohybrid approaches for brain repair - sociological perspective

Report on the stateoftheart of biohybrid approaches for brain repair sociological perspective

CMOS-neuron-memristors interaction

Report on CMOSneuronmemristors chip characteristics and function

Alginate hydrogel as bioactive ECM

Report on the bioactive properties of alginate hydrogel as extracellular matrix.

Application of alginate for in vivo grafting

Report on the application of alginate hydrogel as extracellular matrix for in vivo grafting

Websites, patent fillings, videos etc. (1)

Project website

The project website is online.

Publications

Peer reviewed articles (20)

2022 Roadmap on Neuromorphic Computing and Engineering

Auteurs: Dennis V Christensen; Regina Dittmann; Bernabe Linares-Barranco; Abu Sebastian; Manuel Le Gallo; Andrea Redaelli; Stefan Slesazeck; Thomas Mikolajick; Sabina Spiga; Stephan Menzel; Ilia Valov; Gianluca Milano; Carlo Ricciardi; Shi-Jun Liang; Feng Miao; Mario Lanza; Tyler J Quill; Scott T Keene; Alberto Salleo; Julie Grollier; Danijela Marković; Alice Mizrahi; Peng Yao; J Joshua Yang; Giacomo Indi
Publié dans: Furber , S & et , A 2022 , ' 2022 roadmap on neuromorphic computing and engineering ' , Neuromorphic Computing and Engineering , vol. 2 , no. 2 . https://doi.org/10.1088/2634-4386/ac4a83, Numéro 2022, 2022, ISSN 2634-4386
Éditeur: IOP
DOI: 10.17863/cam.85140

Toward Closed-Loop Electrical Stimulation of Neuronal Systems: A Review

Auteurs: Jarno M. A. Tanskanen, Annika Ahtiainen, Jari A. K. Hyttinen
Publié dans: Bioelectricity, Numéro 4, 2020, Page(s) 328-347, ISSN 2576-3113
Éditeur: Mary Ann Liebert, Inc., publishers
DOI: 10.1089/bioe.2020.0028

Self‐Powered Implantable Medical Devices: Photovoltaic Energy Harvesting Review

Auteurs: Jinwei Zhao, Rami Ghannam, Kaung Oo Htet, Yuchi Liu, Man‐kay Law, Vellaisamy A. L. Roy, Bruno Michel, Muhammad Ali Imran, Hadi Heidari
Publié dans: Advanced Healthcare Materials, Numéro 9/17, 2020, Page(s) 2000779, ISSN 2192-2640
Éditeur: John Wiley and Sons Ltd
DOI: 10.1002/adhm.202000779

Murine cerebral organoids develop network of functional neurons and hippocampal brain region identity.

Auteurs: Ciarpella F, Zamfir RG, Campanelli A, Ren E, Pedrotti G, Bottani E, Caron D, Di Chio M, Ahtiainen A, Malpeli G, Malerba G, Bardoni R, Fumagalli G, Hyttinen J, Bifari F, Palazzolo G, Panuccio G, Curia G, Decimo I.
Publié dans: iScience, Numéro 2021, 2021, ISSN 2589-0042
Éditeur: Cell Press Elsevier Inc
DOI: 10.1016/j.isci.2021.103438

Mimicking CA3 Temporal Dynamics Controls Limbic Ictogenesis

Auteurs: Davide Caron, Angel Canal-Alonso, Gabriella Panuccio
Publié dans: MDPI Biology - Neuroscience, Numéro 2022, 2022, ISSN 2079-7737
Éditeur: Multidisciplinary Digital Publishing Institute
DOI: 10.3390/biology11030371

Bioresorbable Insertion Aids for Brain Implantable Flexible Probes: A Comparative Study on Silk Fibroin, Alginate, and Disaccharides

Auteurs: Cerezo-Sanchez, Maria; Mcglynn, Eve; Bartoletti, Stefania; Prasad Yalagala, Bhavani; CASADEI GAROFANI, Beatrice; Capodiferro, Arianna; Russell, Ewan; Palazzolo, Gemma; Walton, Finlay; Curia, Giulia; Heidari, Hadi.
Publié dans: ADVANCED NANOBIOMED RESEARCH, Numéro 2023, 2023, ISSN 2699-9307
Éditeur: Wiley-VCH
DOI: 10.1002/anbr.202200117

Astrocytes Exhibit a Protective Role in Neuronal Firing Patterns under Chemically Induced Seizures in Neuron–Astrocyte Co-Cultures

Auteurs: Annika Ahtiainen, Barbara Genocchi, Jarno M. A. Tanskanen, Michael T. Barros, Jari A. K. Hyttinen, Kerstin Lenk
Publié dans: International Journal of Molecular Sciences, Numéro 23, 2021, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms222312770

The Future of Neuroscience: Flexible and Wireless Implantable Neural Electronics

Auteurs: Eve McGlynn, Vahid Nabaei, Elisa Ren, Gabriel Galeote-Checa, Rupam Das, Giulia Curia, Hadi Heidari
Publié dans: Advanced Science, 2021, ISSN 2198-3844
Éditeur: 2021
DOI: 10.1002/advs.202002693

Magneto-Optogenetic Deep-Brain Multimodal Neurostimulation

Auteurs: Finlay Walton; Eve McGlynn; Rupam Das; Hongze Zhong; Hadi Heidari; Patrick Degenaar
Publié dans: Advanced Intelligent Systems, Numéro 3, 2021, ISSN 2640-4567
Éditeur: Wiley
DOI: 10.1002/aisy.202100082

Preface to 'Advanced neurotechnologies: Translating innovation for health and well-being'

Auteurs: Das, R.; Curia, G.; Heidari, H.
Publié dans: PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES A: MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES, Numéro 2022, 2022, ISSN 1364-503X
Éditeur: Royal Society of London
DOI: 10.1098/rsta.2021.0004

Synaptic Reshaping and Neuronal Outcomes in the Temporal Lobe Epilepsy

Auteurs: Ren, E.; Curia, G.
Publié dans: International Journal of Molecular Sciences, Numéro 2021, 2021, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22083860

Nanotechnology Enables Novel Modalities for Neuromodulation

Auteurs: Xiao Yang, Eve McGlynn, Rupam Das, Sergiu P. Paşca, Bianxiao Cui, Hadi Heidari
Publié dans: Advanced Materials, 2021, ISSN 1521-4095
Éditeur: Wiley
DOI: 10.1002/adma.202103208

Electrophysiology Read-Out Tools for Brain-on-Chip Biotechnology

Auteurs: Csaba Forro, Davide Caron, Gian Angotzi, Vincenzo Gallo, Luca Berdondini, Francesca Santoro, Gemma Palazzolo, Gabriella Panuccio
Publié dans: Micromachines, Numéro 12/2, 2021, Page(s) 124, ISSN 2072-666X
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/mi12020124

Environmental Enrichment Induces Meningeal Niche Remodeling through TrkB-Mediated Signaling

Auteurs: Stefania Zorzin; Andrea Corsi; Francesca Ciarpella; Emanuela Bottani; Sissi Dolci; Giorgio Malpeli; Annachiara Pino; Alessia Amenta; Guido Franceso Fumagalli; Cristiano Chiamulera; Francesco Bifari; Ilaria Decimo
Publié dans: International Journal of Molecular Sciences, Numéro 2021, 2021, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms221910657

Metabolism of Stem and Progenitor Cells: Proper Methods to Answer Specific Questions.

Auteurs: Giuseppe Martano; Elena Monica Borroni; Elena Monica Borroni; Egesta Lopci; Maria Grazia Cattaneo; Milena Mattioli; Angela Bachi; Ilaria Decimo; Francesco Bifari
Publié dans: Frontiers in Molecular Neuroscience, Vol 12 (2019), Numéro 2, 2019, ISSN 1662-5099
Éditeur: Frontiers Research Foundation
DOI: 10.3389/fnmol.2019.00151

Neuromorphic Spiking Neural Networks and Their Memristor-CMOS Hardware Implementations

Auteurs: Luis Camuñas-Mesa, Bernabé Linares-Barranco, Teresa Serrano-Gotarredona
Publié dans: Materials, Numéro 12/17, 2019, Page(s) 2745, ISSN 1996-1944
Éditeur: MDPI Open Access Publishing
DOI: 10.3390/ma12172745

Biointegrated and Wirelessly Powered Implantable Brain Devices: A Review

Auteurs: Rupam Das, Farshad Moradi, Hadi Heidari
Publié dans: IEEE Transactions on Biomedical Circuits and Systems, 2019, Page(s) 1-1, ISSN 1932-4545
Éditeur: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tbcas.2020.2966920

Causal coupling inference from multivariate time series based on ordinal partition transition networks

Auteurs: Narayan Puthanmadam Subramaniyam; Reik V. Donner; Davide Caron; Gabriella Panuccio; Jari Hyttinen
Publié dans: Nonlinear Dynamics, Numéro 1, 2021, Page(s) 555-578, ISSN 1573-269X
Éditeur: Springer Nature B.V.
DOI: 10.1007/s11071-021-06610-0

Biohybrid restoration of the hippocampal loop re-establishes the non-seizing state in an in vitro model of limbic seizures

Auteurs: Davide Caron, Stefano Buccelli, Angel Canal-Alonso, Javad Farsani, Giacomo Pruzzo, Bernabé Linares Barranco, Juan Manuel Corchado, Michela Chiappalone and Gabriella Panuccio
Publié dans: Journal of Neural Engineering, Numéro 2023, 2023, ISSN 1741-2552
Éditeur: IOP
DOI: 10.1088/1741-2552/ace931

Neuromorphic Low-Power Inference on Memristive Crossbars With On-Chip Offset Calibration

Auteurs: Charanraj Mohan; Luis A. Camunas-Mesa; Jose M. de la Rosa; Elisa Vianello; Teresa Serrano-Gotarredona; Bernabe Linares-Barranco
Publié dans: IEEE Access, Numéro 28, 2021, ISSN 2169-3536
Éditeur: Institute of Electrical and Electronics Engineers Inc.
DOI: 10.1109/access.2021.3063437

Conference proceedings (11)

Implementation of Binary Stochastic STDP Learning Using Chalcogenide-Based Memristive Devices

Auteurs: Charanraj Mohan; Luis A. Camunas-Mesa; J.M. de la Rosa; Teresa Serrano-Gotarredona; Bernabe Linares-Barranco
Publié dans: 2021 IEEE International Symposium on Circuits and Systems (ISCAS), Numéro 27, 2021
Éditeur: IEEE
DOI: 10.1109/iscas51556.2021.9401159

Flexible Wirelessly Powered Implantable Device

Auteurs: Gabriel Galeote-Checa, Kaya Uke, Linta Sohail, Rupam Das, Hadi Heidari
Publié dans: 2019 26th IEEE International Conference on Electronics, Circuits and Systems (ICECS), 2019, Page(s) 891-894, ISBN 978-1-7281-0996-1
Éditeur: IEEE
DOI: 10.1109/icecs46596.2019.8964995

Neural Microprobe Device Modelling for Implant Micromotions Failure Mitigation

Auteurs: Vahid Nabaei, Gabriella Panuccio, Hadi Heidari
Publié dans: 2020 IEEE International Symposium on Circuits and Systems (ISCAS), 2020, Page(s) 1-5, ISBN 978-1-7281-3320-1
Éditeur: IEEE
DOI: 10.1109/iscas45731.2020.9180497

Extracellular Electrical Stimulation-based in Vitro Neuroscience: A Minireview of Methods and a Paradigm Shift Proposal

Auteurs: Jarno M. A. Tanskanen, Annika Ahtiainen, Jari A. K. Hyttinen
Publié dans: 2019 26th IEEE International Conference on Electronics, Circuits and Systems (ICECS), 2019, Page(s) 883-886, ISBN 978-1-7281-0996-1
Éditeur: IEEE
DOI: 10.1109/icecs46596.2019.8964854

Digital-Signal-Processor Realization of Izhikevich Neural Network for Real-Time Interaction with Electrophysiology Experiments

Auteurs: Javad Ahmadi-Farsani, Bernabe Linares-Barranco, Teresa Serrano-Gotarredona
Publié dans: 2019 26th IEEE International Conference on Electronics, Circuits and Systems (ICECS), 2019, Page(s) 899-902, ISBN 978-1-7281-0996-1
Éditeur: IEEE
DOI: 10.1109/icecs46596.2019.8965064

A Volatile RRAM Synapse for Neuromorphic Computing

Auteurs: E. Covi, D. Ielmini, Y.-H. Lin, W. Wang, T. Stecconi, V. Milo, A. Bricalli, E. Ambrosi, G. Pedretti, T.-Y. Tseng
Publié dans: 2019 26th IEEE International Conference on Electronics, Circuits and Systems (ICECS), 2019, Page(s) 903-906, ISBN 978-1-7281-0996-1
Éditeur: IEEE
DOI: 10.1109/icecs46596.2019.8965044

A Low-Noise High Input Impedance Analog Front-End Design for Neural Recording Implant

Auteurs: Hai Au Huynh, Margherita Ronchini, Amin Rashidi, Mohammad Tohidi, Hooman Farkhani, Farshad Moradi
Publié dans: 2019 26th IEEE International Conference on Electronics, Circuits and Systems (ICECS), 2019, Page(s) 887-890, ISBN 978-1-7281-0996-1
Éditeur: IEEE
DOI: 10.1109/icecs46596.2019.8964899

Astrocytic control in in vitro and simulated neuron-astrocyte networks

Auteurs: Barbara Genocchi, Annika Ahtiainen, Michael T. Barros, Jarno M.A. Tanskanen, Jari Hyttinen, Kerstin Lenk
Publié dans: Proceedings of the Eight Annual ACM International Conference on Nanoscale Computing and Communication, Numéro September, 2021, 2021, ISBN 978-1-4503-8710-1
Éditeur: Association for Computing Machinery
DOI: 10.1145/3477206.3477458

Experimental Body-Input Three-Stage DC Offset Calibration Scheme for Memristive Crossbar

Auteurs: Charanraj Mohan; Luis A. Camunas-Mesa; Elisa Vianello; Carlo Reita; Jose M. de la Rosa; Teresa Serrano-Gotarredona; Bernabe Linares-Barranco
Publié dans: ISCAS, Numéro 25, 2021
Éditeur: IEEE
DOI: 10.1109/iscas45731.2020.9180811

A Self-tracked High-dielectric Wireless Power Transfer System for Neural Implants

Auteurs: Rupam Das, Hadi Heidari
Publié dans: 2019 26th IEEE International Conference on Electronics, Circuits and Systems (ICECS), 2019, Page(s) 111-112, ISBN 978-1-7281-0996-1
Éditeur: IEEE
DOI: 10.1109/icecs46596.2019.8964953

Astrocytes in modulating subcellular, cellular and intercellular molecular neuronal communication

Auteurs: Jari Hyttinen, Barbara Genocchi, Annika Ahtiainen, Jarno M.A. Tanskanen, Kerstin Lenk, Michael T. Barros
Publié dans: Proceedings of the Eight Annual ACM International Conference on Nanoscale Computing and Communication, Numéro September, 2021, 2021, ISBN 978-1-4503-8710-1
Éditeur: Association for Computing Machinery
DOI: 10.1145/3477206.3477460

Book chapters (1)

Brentano’s Mathematical Foundation of Science

Auteurs: Ierna, Carlo; Tănăsescu, Ion; Bejinariu, Alexandru; Krantz Gabriel, Susan; Stoenescu, Constantin
Publié dans: Brentano and the Positive Philosophy of Comte and Mill : With Translations of Original Writings on Philosophy as Science by Franz Brentano, Numéro 10, 2022, Page(s) 309-330, ISBN 9783110738858
Éditeur: De Gruyter
DOI: 10.1515/9783110734645-013