FoodSafeR addresses existing and emerging food safety hazards and risks, by assessing both chemical and microbiological food safety across the food production chain. In WP1, a food system analysis of drives of change from inside and outside our food systems was performed to early identify emerging food safety hazards that might arise related to these changes. Based on in-depth literature meta-analysis and input from project partners and food safety professionals, the drivers for emergence of food safety hazards were identified. These were then categorized based on STEEP principles (Social, Technological, Economical, Environmental and Political), prioritized based on a survey of hazards most associated with each driver, and a report on these drivers was successfully submitted as a project deliverable (D1.1). For each of the prioritized drivers for emergence of food safety hazards, one or more indicators were identified. Available data and datasets on these indicators were search for from open-source databases, which later will be linked to the open digital hub (in WP4). Selected indicators, together with their related data sources have been described in D1.2. Microbiological food safety hazards and risks are being evaluated throughout the food production chain in WP2. In addition to expanding existing FoodChain-Lab software using feedback from food producers, we assess the microbiological risks associated with novel or low-regulated food chains based on six food type case studies. Many microbiological analyses have been completed, including assessment of hygiene parameters and pathogen detection for each of these case studies. A published catalogue of these results will be submitted in September 2024 (Milestone 7). Methods have been refined and established for enrichment and classification of persistent strains of Listeria monocytogenes, detection of foodborne viruses in ready-to-eat pork products, and for the extraction and sequencing of antimicrobial resistance genes from fish raised in aquaculture systems. A literature analysis and a genome-based study are in progress toward the identification of genes underlying the persistence phenomenon in Listeria monocytogenes. Chemical food safety hazards and the emergence of associated risks are being investigated in WP3. Topics include detection and prediction of mycotoxin and plant toxin emergence, fate and concurrent potential reduction of furans (focusing on food sauces processing) and mycotoxins during thermal processing (for instance concerning gluten-free products), and detection of illegal addition of toxic chemicals to food (such as turmeric-lead chromate case, where an extensive research/sampling network has been established across Cameroon, India, Bangladesh, Ghana, Philippines, Nigeria, and Tanzania). Available models for prediction of fungal infection and mycotoxin production in grains and tomatoes were surveyed to get an overview of the state-of-the-art. Relevant mycotoxins and plant toxins have been identified and methods were established for qualitative and quantitative determination of these components.