Minimally Invasive Neuromodulation Implant and implantation procedure based on ground-breaking GRAPHene technology for treating brain disorders

Información del proyecto

MINIGRAPH

Identificador del acuerdo de subvención: 101070865

DOI

10.3030/101070865

Proyecto cerrado

Fecha de la firma de la CE 27 Junio 2022

Fecha de inicio 1 Octubre 2022

Fecha de finalización 30 Junio 2026

Financiado con arreglo a

• The European Innovation Council (EIC)

Coste total

€ 4 428 402,50

Aportación de la UE

€ 4 428 402,50

Coordinado por

FUNDACIO INSTITUT CATALA DE NANOCIENCIA I NANOTECNOLOGIA
Spain

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

Documents, reports (7)

Report with stakeholder groups

Report with updated stakeholder groups

Documentation with mock neural leads characteristics
Data management plan 1

Define the data Management Plan

Website up and running

Development and operation of the projects website

Plan for Dissemination, Exploitation &Communication

Define the Dissemination Exploitation and Communication Plan

Strategy of regulatory pathways and needs
Syllabus of the portfolio seminar series

Publicaciones

Peer reviewed articles (19)

Identification of the N-terminal residues responsible for the differential microdomain localization of CYP1A1 and CYP1A2

Autores: Robert M. Fuchs, James R. Reed, J. Patrick Connick, Markéta Paloncýová, Martin Šrejber, Petra Čechová, Michal Otyepka, Marilyn K. Eyer, Wayne L. Backes
Publicado en: Journal of Biological Chemistry, Edición 300, 2024, ISSN 0021-9258
Editor: Elsevier BV
DOI: 10.1016/J.JBC.2024.107891

Long‐Term Stable Neural Interfaces with Nanoporous Graphene Electrodes and Hybrid Polyimide‐Aluminium Oxide Encapsulation

Autores: Georgios Alexandros Katirtsidis; Xavier Illa; Nicola Ria; Elena del Corro; Eduard Masvidal Codina; Jose A. Garrido
Publicado en: Small Methods, 2025, ISSN 2366-9608
Editor: Wiley
DOI: 10.1002/SMTD.202501720

The impact of graphene oxide nanosheet lateral dimensions on the electrochemical performance of nanoporous graphene-based electrodes

Autores: Bernicola, María del Pilar; Madrid-Gimeno, Miquel; Murillo Cremaes, Nerea; Battisti, Tommaso; Lozano, Neus; Kostarelos, Kostas; Garrido, Jose A.; Del Corro, Elena
Publicado en: Diamond and Related Materials, 2024, ISSN 0922-3444
Editor: Elsevier
DOI: 10.1016/J.DIAMOND.2024.111722

Label-free detection and mapping of graphene oxide in single HeLa cells based on MCR-Raman spectroscopy

Autores: Zuzana Chaloupková; Ludmila Žárská; Jan Belza; Kateřina Poláková
Publicado en: Analytical Methods, 2023, ISSN 1759-9679
Editor: Royal Society of Chemistry
DOI: 10.1039/D3AY01122D

Nature Communications

Autores: Nicola Ria; Ahmed Eladly; Eduard Masvidal-Codina; Xavi Illa; Anton Guimerà; Kate Hills; Ramon Garcia-Cortadella; Fikret Taygun Duvan; Samuel M. Flaherty; Michal Prokop; Rob. C. Wykes; Kostas Kostarelos; Jose A. Garrido
Publicado en: Nature Communications, 2025, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/S41467-025-58156-Z

Computational Methods for Modeling Lipid-Mediated Active Pharmaceutical Ingredient Delivery

Autores: Paloncýová, Markéta; Valério, Mariana; dos Santos, Ricardo; Kührová, Petra; Šrejber, Martin; Čechová, Petra; Dobchev, Dimitar; Balsubramani, Akshay; Banáš, Pavel; Agarwal, Vikram; Souza, Paulo; Otyepka, Michal
Publicado en: Molecular Pharmaceutics, 2025, ISSN 1543-8392
Editor: American Chemical Society (ACS) Publications
DOI: 10.1021/ACS.MOLPHARMACEUT.4C00744

Wood‐Based Bioelectronics: Lignosulfonate‐Based Conductive Biocomposites for Paper Organic Electrochemical Transistors

Autores: Grabner, Tobias; Matura, Katharina; Hradilová, Šárka; Cobet, Munise; Opletalová, Ariana; Polakova, Kateřina; Operamolla, Alessandra; Sariciftci, Niyazi Serdar; Tekoglu, Serpil
Publicado en: Advanced Electronic Materials, 2026, ISSN 2199-160X
Editor: Wiley Advanced
DOI: 10.1002/AELM.202500809

Flexible graphene-based neurotechnology for high-precision deep brain mapping and neuromodulation in Parkinsonian rats

Autores: Nicola Ria, Ahmed Eladly, Eduard Masvidal-Codina, Xavi Illa, Anton Guimerà, Kate Hills, Ramon Garcia-Cortadella, Fikret Taygun Duvan, Samuel M. Flaherty, Michal Prokop, Rob. C. Wykes, Kostas Kostarelos, Jose A. Garrido
Publicado en: Nature Communications, Edición 16, 2025, ISSN 2041-1723
Editor: Springer Science and Business Media LLC
DOI: 10.1038/S41467-025-58156-Z

Online prediction of optimal deep brain stimulation contacts from local field potentials in Parkinson’s disease

Autores: Muller, Marjolein; Scafa, Stefano; Hanafi, Ibrahem; Varescon, Camille; Palmisano, Chiara; van der Gaag, Saskia; Zutt, Rodi; van der Gaag, Niels A.; Hoffmann, Carel F. E.; Bloch, Jocelyne; Jiménez, Mayte Castro; Bally, Julien F.; Capetian, Philipp; Isaias, Ioannis U.; Moraud, Eduardo M.; Contarino, M. Fiorella
Publicado en: npj Parkinson's Disease, 2025, ISSN 2373-8057
Editor: Nature
DOI: 10.1038/S41531-025-01092-Y

From subthalamic local field potentials to the selection of chronic deep brain stimulation contacts in Parkinson's disease - A systematic review

Autores: Marjolein Muller; Mark F.C. van Leeuwen; Carel F. Hoffmann; Niels A. van der Gaag; Rodi Zutt; Saskia van der Gaag; Alfred C. Schouten; M. Fiorella Contarino
Publicado en: Brain Stimulation, 2024, ISSN 1876-4754
Editor: Science Direct
DOI: 10.1101/2024.10.29.24316351

Label-free detection and mapping of graphene oxide in single HeLa cells based on MCR-Raman spectroscopy

Autores: Zuzana Chaloupková, Ludmila Žárská, Jan Belza, Kateřina Poláková
Publicado en: Analytical Methods, Edición 42, 2023, ISSN 1759-9660
Editor: Royal Society of Chemistry
DOI: 10.1039/D3AY01122D

Biocompatibility assessment of organic semiconductor pigments epindolidione and quinacridone

Autores: Sarka Hradilova, Tana Zavodna, Jan Belza, Mihai Irimia-Vladu, Niyazi Serdar Sariciftci, Cigdem Yumusak, Katerina Polakova
Publicado en: Microchemical Journal, Edición 202, 2024, ISSN 0026-265X
Editor: Elsevier BV
DOI: 10.1016/J.MICROC.2024.110740

Mechanistic insights into interactions between ionizable lipid nanodroplets and biomembranes

Autores: Petra Čechová, Markéta Paloncýová, Martin Šrejber, Michal Otyepka
Publicado en: Journal of Biomolecular Structure and Dynamics, Edición 43, 2025, ISSN 0739-1102
Editor: Informa UK Limited
DOI: 10.1080/07391102.2024.2329307

On the Electrochemical Activation of Nanoporous Reduced Graphene Oxide Electrodes Studied by In Situ/Operando Electrochemical Techniques

Autores: Bernicola, María; Lounasvuori, Mailis; Padilla‐pantoja, Jessica; Santiso, Jose; Debiemme‐chouvy, Catherine; Perrot, Hubert; Petit, Tristan; Garrido, Jose; del Corro, Elena
Publicado en: Advanced Functional Materials, 2024, ISSN 1096-987X
Editor: Wiley
DOI: 10.1002/ADFM.202408441

Double Fault: Artifacts Produced by Physical Activity Can Impact the Efficacy of Chronic Local Field Potential Recordings and Adaptive Stimulation

Autores: Marjolein Muller, M. Fiorella Contarino
Publicado en: Movement Disorders Clinical Practice, Edición 13, 2026, ISSN 2330-1619
Editor: Wiley
DOI: 10.1002/MDC3.70480

Nanoporous graphene-based thin-film microelectrodes for in vivo high-resolution neural recording and stimulation

Autores: Viana, Damià; Walston, Steven; Masvidal-Codina, Eduard; Illa, Xavi; Rodríguez-Meana, Bruno; del Valle, Jaume; Hayward, Andrew; Dodd, Abbie; Loret, Thomas; Prats-Alfonso, Elisabet; de la Oliva, Natàlia; Palma, Marie; del Corro, Elena; del Pilar Bernicola, María; Rodríguez-Lucas, Elisa; Gener, Thomas; de la Cruz, Jose Manuel; Torres-Miranda, Miguel; Duvan, Fikret Taygun; Ria, Nicola; Sperling, Justin; Martí-Sánchez, Sara; Spadaro, Maria Chiara; Hébert, Clément; Savage, Sinead; Arbiol, Jordi; Guimerà-Brunet, Anton; Puig, M. Victoria; Yvert, Blaise; Navarro, Xavier; Kostarelos, Kostas; Garrido, Jose
Publicado en: Nature Nanotechnology, 2024, ISSN 1748-3395
Editor: Nature
DOI: 10.1038/S41565-023-01570-5

Journal of Biological Chemistry

Autores: Robert M. Fuchs; James R. Reed; J. Patrick Connick; Markéta Paloncýová; Martin Šrejber; Petra Čechová; Michal Otyepka; Marilyn K. Eyer; Wayne L. Backes
Publicado en: Journal of Biological Chemistry, 2024, ISSN 0021-9258
Editor: American Society for Biochemistry and Molecular Biology
DOI: 10.1016/J.JBC.2024.107891

Atomistic Insights Into Interaction of Doxorubicin With <scp>DNA</scp>: From Duplex to Nucleosome

Autores: Andrea Nedelníková; Petr Stadlbauer; Michal Otyepka; Petra Kührová; Markéta Paloncýová
Publicado en: Journal of Computational Chemistry, 2025, ISSN 1096-987X
Editor: Wiley
DOI: 10.5281/ZENODO.14501055

Morphology-dependent near-infrared photothermal activity of plasmonic TiN nanobars and nanospheres for anticancer, antibacterial therapy and deep in vivo photoacoustic imaging

Autores: Katerina Polakova, Sourav Rej, Sarka Hradilova, Jan Belza, Tomas Malina, Katerina Barton Tomankova, Renata Vecerova, Petr Matous, Petr Paral, Ariana Opletalova, Jana Soukupova, Tomas Pluhacek, Ludek Sefc, Radek Zboril, Stepan Kment, Alberto Naldoni
Publicado en: Applied Surface Science Advances, Edición 26, 2026, ISSN 2666-5239
Editor: Elsevier BV
DOI: 10.1016/J.APSADV.2025.100713

Conference proceedings (1)

Manufacturing and Characterization of Thin-Film Tantalum Pentoxide Integrated Capacitors

Autores: Andrei Costina, Markus Wöhrmann, Michael Schiffer, Martin Schneider-Ramelow
Publicado en: 2024 IEEE 10th Electronics System-Integration Technology Conference (ESTC), Edición 23, 2024
Editor: IEEE
DOI: 10.1109/ESTC60143.2024.10711996