Next-Gen NMR Prediction and Analysis: A Cutting-Edge Tool for High-Precision Structure Identification

Projektinformationen

HQS-NextNMR

ID Finanzhilfevereinbarung: 101214526

DOI 10.3030/101214526

EK-Unterschriftsdatum 5 März 2025

Startdatum 1 März 2025

Enddatum 28 Februar 2027

Finanziert unter

• The European Innovation Council (EIC)

Gesamtkosten Keine Daten

EU-Beitrag € 2 499 990,63

Koordiniert durch

HQS QUANTUM SIMULATIONS GMBH
Germany

Ziel

The proposal aims to advance diagnostic technology by enhancing Nuclear Magnetic Resonance (NMR) as a tool for personalized medicine. Current NMR techniques face limitations in sensitivity, resolution, and uncertainty quantification, particularly in analyzing complex biological mixtures. These challenges hinder its potential to deliver the precise, non-invasive diagnostics required in personalized healthcare. Our solution is an advanced NMR software that integrates quantum-chemical calculations with empirical data to significantly improve NMR's accuracy and reliability.
Current methods fall short in accuracy when dealing with complex or novel molecular structures. Our tool addresses these limitations by providing accurate conformer sampling and error propagation techniques to quantify uncertainties in peak assignments and chemical shift variations, which are crucial for high-precision analysis. Additionally, it aims to enable low-field NMR devices as a viable option for advanced diagnostics, particularly in cost-sensitive sectors such as pharmaceuticals, biotechnology, and environmental science. The software automates many aspects of NMR analysis, reducing time and effort for researchers while improving accuracy, enabling wider adoption and faster results.
This innovation is particularly relevant to the EIC Transition programs focus on bringing deep-tech innovations from lab to market. The software has the potential to revolutionize fields like drug discovery, personalized medicine, and environmental monitoring, opening new markets for point-of-care diagnostics and expanding the use of low-field NMR in industries previously restricted by high costs. Early interest from key players, including Merck and the University Medical Center Freiburg, supports the commercialization potential.

Wissenschaftliches Gebiet (EuroSciVoc)

CORDIS klassifiziert Projekte mit EuroSciVoc, einer mehrsprachigen Taxonomie der Wissenschaftsbereiche, durch einen halbautomatischen Prozess, der auf Verfahren der Verarbeitung natürlicher Sprache beruht.

• Naturwissenschaften › Informatik und Informationswissenschaften › Software
• Medizin- und Gesundheitswissenschaften › Grundlagenmedizin › Pharmakologie und Pharmazie › Arzneimittel

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Schlüsselbegriffe

• Quantum-enhanced diagnostics
• Molecular imaging
• Non-invasive analysis
• Spectral prediction
• Conformer sampling
• Biomedical applications
• Metabolomics tools

Programm/Programme

• HORIZON.3.1 - The European Innovation Council (EIC) Main Programme

Thema/Themen

• HORIZON-EIC-2024-TRANSITIONOPEN-01 - Transition Open 2024

Aufforderung zur Vorschlagseinreichung

HORIZON-EIC-2024-TRANSITION-01

Finanzierungsplan

HORIZON-EIC - HORIZON EIC Grants

Koordinator

HQS QUANTUM SIMULATIONS GMBH

• Netto-EU-Beitrag: € 2 499 990,63
• Adresse: RINTHEIMER STRASSE 23 ; 76131 KARLSRUHE ; Deutschland
• KMU Die Organisation definierte sich zum Zeitpunkt der Unterzeichnung der Finanzhilfevereinbarung selbst als KMU (Kleine und mittlere Unternehmen). Ja:
  Region
  Baden-Württemberg › Karlsruhe › Karlsruhe, Stadtkreis
• Region: Baden-Württemberg › Karlsruhe › Karlsruhe, Stadtkreis
• Aktivitätstyp: Private for-profit entities (excluding Higher or Secondary Education Establishments)
• Gesamtkosten: Keine Daten