Objectif Cancer accounts for nearly one-quarter of deaths in the developed world, exceeded only by heart diseases. One of the key strategies in cancer prevention is early diagnosis through cancer screening programs. Estimates of the premature deaths that could have been avoided through cancer screening vary from 3% to 35%, depending on a variety of assumptions. Beyond the potential to reduce mortality, screening may reduce cancer morbidity since treatment for earlier-stage cancers is often less aggressive than that for more advanced-stage cancers. Currently many of these screening programs, have issues with false negative results, long time delays to obtaining the results, which increase patient anxiety and delays in starting treatments. In this project we will develop a novel rapid real time PCR/probe technology, in a microarray biochip format with the corresponding automated instrumentation for use as a rapid “point of care” diagnostic device. Cervical cancer and its associated virus, human papilloma virus is the model system which will be used to develop this novel automated cancer screening technology. The novel real time PCR technology will permit detection of panels of multiple biomarkers in a single PCR reaction. The partners have already developed prototype technology which partly demonstrates a microarray approach to real time PCR. The project will build on this, providing the innovation needed to transform a promising technology to an integrated system suitable for practical use at point-of-care setting. The consortium includes four research institutes and two SMEs, who have extensive experience with real time PCR and microarray technologies, and are motivated to commercialise results. In addition partners 7 will act as end user, validating the system in a clinical setting. Champ scientifique social sciencessociologydemographymortalitynatural sciencesbiological sciencesmicrobiologyvirologymedical and health sciencesclinical medicineoncologycervical cancer Mots‑clés cervical cancer point-of-care real-time PCR Programme(s) FP7-HEALTH - Specific Programme "Cooperation": Health Thème(s) HEALTH-2007-2.4.1-4 - Novel cancer screening methods Appel à propositions FP7-HEALTH-2007-A Voir d’autres projets de cet appel Régime de financement CP-FP - Small or medium-scale focused research project Coordinateur GENOID MOLEKULARBIOLOGIAI KUTATO, GYARTO ES EGESZSEGUGYI SZOLGALATO KFT Contribution de l’UE € 427 114,00 Adresse ROPPENTYU UTCA 48 1139 BUDAPEST Hongrie Voir sur la carte Type d’activité Private for-profit entities (excluding Higher or Secondary Education Establishments) Contact administratif Csaba Jeney (Dr.) Liens Contacter l’organisation Opens in new window Coût total Aucune donnée Participants (6) Trier par ordre alphabétique Trier par contribution de l’UE Tout développer Tout réduire FRAUNHOFER GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG EV Allemagne Contribution de l’UE € 787 024,00 Adresse HANSASTRASSE 27C 80686 Munchen Voir sur la carte Région Bayern Oberbayern München, Kreisfreie Stadt Type d’activité Research Organisations Contact administratif Maximilian Steiert (Mr.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH Autriche Contribution de l’UE € 145 728,00 Adresse GIEFINGGASSE 4 1210 Wien Voir sur la carte Région Ostösterreich Wien Wien Type d’activité Research Organisations Contact administratif Alexander Svejkovsky (Mr.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée BIOFLUIDIX GMBH Allemagne Contribution de l’UE € 364 660,00 Adresse GEORGE KOEHLER ALLEE 103 79110 FREIBURG IM BREISGAU Voir sur la carte Type d’activité Private for-profit entities (excluding Higher or Secondary Education Establishments) Contact administratif Peter Koltay (Dr.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée JENOPTIK POLYMER SYSTEMS GMBH Allemagne Contribution de l’UE € 270 460,00 Adresse AM SANDBERG 2 07819 TRIPTIS Voir sur la carte Type d’activité Private for-profit entities (excluding Higher or Secondary Education Establishments) Contact administratif Janine Müller (Ms.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée ALBERT-LUDWIGS-UNIVERSITAET FREIBURG Allemagne Contribution de l’UE € 492 000,00 Adresse FAHNENBERGPLATZ 79098 Freiburg Voir sur la carte Région Baden-Württemberg Freiburg Freiburg im Breisgau, Stadtkreis Type d’activité Higher or Secondary Education Establishments Contact administratif Felix Von Stetten (Dr.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN Irlande Contribution de l’UE € 512 783,00 Adresse COLLEGE GREEN TRINITY COLLEGE D02 CX56 DUBLIN 2 Voir sur la carte Région Ireland Eastern and Midland Dublin Type d’activité Higher or Secondary Education Establishments Contact administratif Deirdre Savage (Ms.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée