Final Report Summary - NANOTRANSPORT (The Behaviour of Aerosols Released to Ambient Air from Nanoparticle Manufacturing - A Pre-normative Study) The objective of the NANOTRANSPORT project was to investigate physical changes which NP aerosols undergo after release into the workplace environment under realistic scenarios. This information is essential to understand the characteristics of NPs when they reach a human receptor after transport over a distance from a NP source. During the whole project period from September 2006 to April 2008, we completed all the tasks proposed, including: - A state-of-the-art study to identify critical parameters governing the behaviour of NP aerosols (responsible contractor: DNV); - A scenario development workshop gathering leading experts to develop realistic exposure scenarios at NP manufacturing sites (responsible contractor: DNV/UniK); - Experimental work to generate test aerosols and investigate their behaviour released in an exposure chamber under different conditions defined in the exposure scenarios (responsible contractor: UniK/Grimm); - Recommendations to European Commission based on experimental results and conclusions (responsible contractor: UniK); - Dissemination of project findings through presentations at national and international conferences, publications at scientific journals and the project website responsible contractor: all partners). The agglomeration dynamic of primary Pt nanoparticles released in a simulated workplace environment was thoroughly characterised in this study, using both experimental data and aerosol dynamic modelling. The results are of importance for defining standard test conditions for inhalation toxicological studies. We observed that agglomerates formed under different scenarios of NP release (e.g. source concentration of NP, ratio of NP and background particles, continuous or discontinuous release, particle size) are different in terms of particle size distribution and attachment to ambient particles. Consequently, the test condition for inhalation toxicological study should be adapted to the specific release mechanisms in workplaces. Related documents Final Report - NANOTRANSPORT (The Behaviour of Aerosols Released to Ambient Air from Nanoparticle Manufacturing - A Pre-normative Study) Other documents The Behaviour of Aerosols Released to Ambient Air from Nanoparticle Manufacturing - A Pre-normative Study (NANOTRANSPORT) - Publishable final activity report
