Objective
The discovery of type III secretion systems during the last decade has dramatically changed our understanding of the molecular basis of bacterial pathogen city. Type III secretion systems are conserved in animal and plant bacterial pathogens and are involved in the delivery of bacterialeffector proteins into the host cells. In plants, the identification of bacterial effectors is of an outstanding importance, since the understanding of the molecular processes leading to disease development and the identification of the corresponding molecular targets in the eucharistic cell opens the way to new biotechnological strategies for crop protection. In the plant pathogen R. solanacearum biochemical and genetic approaches led to the identification of several proteins that are exported through the Type III apparatus. The advent of the genome sequencing projects has facilitated the identification of new effectors based on protein homology or structural features or conservation of a consensus sequence in the corresponding genepromoters. A group of related genes that are called the GALA family and have no similarities in the databases has been identified through analysis of R. solanacearum genome sequence. The predicted proteins contain eucharistic features such as leonine-rich domains, which renders them good candidates as effectors proteins that carry out a function within the plant cell. The aim of this project is to characterise thoroughly this gene family in search for novel type Ill-dependent effectors. The process will include
a) study of their expression profile,
b) mutation and analysis of the resulting phenotype regarding pathogen city,
c) demonstration of protein translocation into plant cells,
d) sub cellular localisation of the protein once inside the plant and
e) identification of molecular targets within the host cell.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- agricultural sciences agriculture, forestry, and fisheries agriculture agronomy plant protection
- natural sciences computer and information sciences databases
- natural sciences biological sciences biochemistry biomolecules proteins
- natural sciences biological sciences genetics mutation
- natural sciences biological sciences genetics genomes
You need to log in or register to use this function
We are sorry... an unexpected error occurred during execution.
You need to be authenticated. Your session might have expired.
Thank you for your feedback. You will soon receive an email to confirm the submission. If you have selected to be notified about the reporting status, you will also be contacted when the reporting status will change.
Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2002-MOBILITY-5
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
PARIS
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.