Obiettivo The aim of the SOUL project is to quantify risks of late health effects associated with low-dose rate exposure to plutonium, strontium and external gamma radiation. This will be done by improving, updating and analysing dosimetric and health data for the Mayak worker cohort (MWC), the extended Techa River cohort (ETRC) and the Techa River offspring cohort (TROC). Key dosimetric elements include electron paramagnetic resonance (EPR) measurements of tooth enamel, photon spectra measurements, luminescence measurements of absorbed doses in bricks, measurements of strontium distributions in teeth, fluorescence in-situ hybridisation (FISH) measurements of chromosome aberrations, and modelling of internal doses of foetuses and infants. The dosimetric work aims to produce updated dose data bases Mayak Doses 2008 and Techa Doses 2008. In order to increase statistical precision and validity, the number of individuals in the cohorts will be extended, and information on vital status and cause of death will be updated. In the TROC, cancer and cardiovascular disorders will be studied as late health effects following exposure early in life. Non-cancer effects will be studied in the ETRC. The pathogenesis of lung cancer in the MWC will be studied in order to improve the current knowledge. The MWC will be used to study cancer incidence, and mortality and morbidity of circulatory diseases such as myocardial infarction and stroke. In the studies, initial feasibility analyses will be followed - if affirmative - by analyses that are based on longer follow-up and dosimetric data bases improved within the framework of SOUL. Although SOUL is expected to give significant input to the understanding of radiation risks, Southern Urals radiation risk research has to be tinued beyond the project mainly because a longer follow-up is needed to fully quantify lifetime risks. Part of the work in SOUL is dedicated to supporting such future analyses. Campo scientifico medical and health sciencesclinical medicineoncologylung cancermedical and health sciencesclinical medicinecardiologycardiovascular diseasesnatural scienceschemical sciencesnuclear chemistryradiation chemistry Programma(i) FP6-EURATOM-RADPROT - Thematic priority - Radiation Protection as part of the specific framework programme for the European Atomic Energy Community, within the multi-annual framework programme 2002-2006. Argomento(i) RAD PROT-2004- 3.3.1.1.-1 - Epidemiological studies of exposed populations in the Southern Urals Invito a presentare proposte EURATOMCALL2004-FIXEDDEADLINE Vedi altri progetti per questo bando Meccanismo di finanziamento IP - Integrated Project Coordinatore HELMHOLTZ ZENTRUM MUENCHEN, DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT Contributo UE Nessun dato Indirizzo lngolstaedter Landstrasse 1 NEUHERBERG Germania Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato Partecipanti (15) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto HEALTH PROTECTION AGENCY Regno Unito Contributo UE Nessun dato Indirizzo 330 High Holborn - Holborn Gate - 7th Floor LONDON Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato URALSKY NAUCHNO-PRAKTICHESKY TSENTR RADIATSIONNOI MEDITSINY Russia Contributo UE Nessun dato Indirizzo Vorovsky street 68A CHELYABINSK Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato SOUTHERN URALS BIOPHYSICS INSTITUTE Russia Contributo UE Nessun dato Indirizzo Ozyorskoye shosse 19 OZYORSK Mostra sulla mappa Costo totale Nessun dato KAROLINSKA INSTITUTET Svezia Contributo UE Nessun dato Indirizzo Nobels vaeg 1 STOCKHOLM Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato GEOSPETZECOLOGIYA Russia Contributo UE Nessun dato Indirizzo Lenin avenue 6 - Building 2 MOSCOW Mostra sulla mappa Costo totale Nessun dato ISTITUTO SUPERIORE DI SANITA Italia Contributo UE Nessun dato Indirizzo Viale Regina Elena 299 ROMA Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato BUNDESAMT FUER STRAHLENSCHUTZ Germania Contributo UE Nessun dato Indirizzo Willy-Brandt-Strasse 5 10149 SALZGITTER Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato ARISTOTELIO PANEPISTIMIO THESSALONIKIS Grecia Contributo UE Nessun dato Indirizzo Administration Building - University Campus THESSALONIKI Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato AKADEMISCH ZIEKENHUIS LEIDEN Paesi Bassi Contributo UE Nessun dato Indirizzo Albinusdreef 2 LEIDEN Mostra sulla mappa Costo totale Nessun dato WESTLAKES SCIENTIFIC CONSULTING LIMITED Regno Unito Contributo UE Nessun dato Indirizzo Westlakes Science and Technology Park MOOR ROW / CUMBRIA Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato TECHNISCHE UNIVERSITAET MUENCHEN Germania Contributo UE Nessun dato Indirizzo Arcisstrasse 21 MUENCHEN Mostra sulla mappa Costo totale Nessun dato INSTITUTE OF METAL PHYSICS, RUSSIAN ACADEMY OF SCIENCES Russia Contributo UE Nessun dato Indirizzo Sofia Kovalevskaya St. 18 YEKATERINBURG Mostra sulla mappa Costo totale Nessun dato UNIVERSITA DEGLI STUDI DI PALERMO Italia Contributo UE Nessun dato Indirizzo PIAZZA MARINA 61 PALERMO Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato UNIVERSITY OF FLORIDA Stati Uniti Contributo UE Nessun dato Indirizzo University Avenue 116550 GAINESVILLE Mostra sulla mappa Costo totale Nessun dato EBERHARD KARLS UNIVERSITAET TUEBINGEN Germania Contributo UE Nessun dato Indirizzo Wilhelmstrasse 7 TUEBINGEN Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato