Objective "Progress in a wide range of disciplines relies on the development of novel instrumentation. Pushing the limits of analytical equipment results in benefits, for example, through the discovery of illness biomarkers. This project is framed in the field of instrumentation development, in particular for the detection of vapors in real time, and with high sensitivity. Here, we propose to join the expertise of an engineering SME (SEADM) and the Swiss Federal Institute of Technology (ETH) to address four main S&T developments:i) Delivery of pre-marketable ionization sources that ultimately will be commercialized as an add-on for pre-existing mass spectrometers (MS). This will represent a cost-effective option for researchers willing to transform their MS systems into efficient detectors of vapors. During this developmental program, we will gain insights into the ionization mechanism of secondary electrospray ionization (SESI), which is the technique at the core of the add-ons to be delivered; ii) SEADM has recently proposed (patented) a SESI source capable of detecting minute gas-samples (parts per quadrillion in the gas phase, equivalent to a few femtograms). We will develop improved SESI ionizers, will couple them to various MS systems, and will use one MS available at ETH to investigate its potential in the analysis of single cell metabolomics; SEADM has developed an ion mobility spectrometer (dubbed DMA), which can be readily interfaced with pre-existing MS instruments. iii)Based on this precedent, a third instrumental development will be a SESI-DMA-MS system iv) suitable for the rapid screening of volatiles in ambient air. Such a platform would complement current commercial alternatives. This plan will be accomplished through the bidirectional exchange of knowledge. As a result, SEADM will ultimately strengthen its position in the market. The ETH will benefit by having access to novel state-of-the-art instrumentation." Fields of science natural scienceschemical sciencesanalytical chemistry Programme(s) FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Topic(s) FP7-PEOPLE-2013-IAPP - Marie Curie Action: "Industry-Academia Partnerships and Pathways" Call for proposal FP7-PEOPLE-2013-IAPP See other projects for this call Funding Scheme MC-IAPP - Industry-Academia Partnerships and Pathways (IAPP) Coordinator EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH EU contribution € 452 385,78 Address Raemistrasse 101 8092 Zuerich Switzerland See on map Region Schweiz/Suisse/Svizzera Zürich Zürich Activity type Higher or Secondary Education Establishments Administrative Contact Pablo Martinez-Lozano Sinues (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data Participants (1) Sort alphabetically Sort by EU Contribution Expand all Collapse all SOCIEDAD EUROPEA DE ANALISIS DIFERENCIAL DE MOVILIDAD SL Spain EU contribution € 463 600,94 Address PARQUE TECNOLOGICO DE BOECILLO PARCELA 205 47151 BOECILLO See on map Region Centro (ES) Castilla y León Valladolid Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Gonzalo Fernandez De La Mora (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data
