Objetivo Alzheimer’s disease (AD) is the major cause of dementia which has no cure at the moment. The overall aim of the work described in this proposal is to create a long-term strategic partnership between Sheffield University (UK), Lisbon University (Portugal), Eli Lilly (UK) and Biofordrug (Italy) in order to develop chemical biology tools for better understanding the role of PrPC in AD and harnessing this understanding to develop novel chemical entities for diagnostic and therapeutics applications.The D3i4AD project brings together a consortium of groups with internationally-leading expertise from academia and industries in chemistry, molecular design and modelling, biochemistry, diagnostic and drug development. Our proposed programme will lead to major increases in the knowledge and capacity of all consortium members, achieved through significant intersectoral exchange of personnel between the partners over the duration of the project (total 134 person months) and through temporary recruitment of 5 new experienced researchers (total 114 person months). The project will thus underpin a substantial programme of intersectoral knowledge transfer and research training and lead to significant innovation and advances in several areas of basic research as well as diagnostics and therapeutics development. These activities will strongly enhance EU standing and international competitiveness in this extremely challenging and increasingly important technological area. Ámbito científico medical and health sciencesbasic medicinepharmacology and pharmacydrug discoverynatural sciencesbiological sciencesbiochemistrymedical and health sciencesbasic medicineneurologydementiaalzheimer Programa(s) FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Tema(s) FP7-PEOPLE-2013-IAPP - Marie Curie Action: "Industry-Academia Partnerships and Pathways" Convocatoria de propuestas FP7-PEOPLE-2013-IAPP Consulte otros proyectos de esta convocatoria Régimen de financiación MC-IAPP - Industry-Academia Partnerships and Pathways (IAPP) Coordinador THE UNIVERSITY OF SHEFFIELD Aportación de la UE € 1 009 134,94 Dirección FIRTH COURT WESTERN BANK S10 2TN Sheffield Reino Unido Ver en el mapa Región Yorkshire and the Humber South Yorkshire Sheffield Tipo de actividad Higher or Secondary Education Establishments Contacto administrativo Andrew King (Mr.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos Participantes (4) Ordenar alfabéticamente Ordenar por aportación de la UE Ampliar todo Contraer todo ELI LILLY AND COMPANY LTD Reino Unido Aportación de la UE € 290 164,16 Dirección LILLY HOUSE BASINGVIEW RG21 4FA Basingstoke Ver en el mapa Región South East (England) Hampshire and Isle of Wight North Hampshire Tipo de actividad Private for-profit entities (excluding Higher or Secondary Education Establishments) Contacto administrativo Magnus W.Walter (Dr.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos BIOFORDRUG SRL Italia Aportación de la UE € 449 415,60 Dirección VIA EDOARDO ORABONA 4 DIP FARMACO CHIMICO UNIV BARI 70125 BARI Ver en el mapa Tipo de actividad Private for-profit entities (excluding Higher or Secondary Education Establishments) Contacto administrativo Nicola Antonio Colabufo (Prof.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos FACULDADE DE CIENCIAS DA UNIVERSIDADE DE LISBOA Portugal Aportación de la UE € 399 591,50 Dirección CAMPO GRANDE C5 PISO 3 1749-016 Lisboa Ver en el mapa Región Continente Área Metropolitana de Lisboa Área Metropolitana de Lisboa Tipo de actividad Higher or Secondary Education Establishments Contacto administrativo Gomes Silvia (Mrs.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos AMORFIX LIFE SCIENCES LTD Canadá Aportación de la UE € 60 591,75 Dirección AMERICAN DRIVE 3403 M2N 2M6 MISSISSAUGA ON Ver en el mapa Tipo de actividad Private for-profit entities (excluding Higher or Secondary Education Establishments) Contacto administrativo Janet Clennett (Ms.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos