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Sensing and predictive treatment of frailty and associated co-morbidities using advanced personalized patient models and advanced interventions

Ziel

Ageing population is steeply increasing worldwide. A consequence of age related decline is the clinical condition of frailty.
Frailty is a biological syndrome of decreased reserve and resistance to stressors, resulting from cumulative declines across multiple physiologic systems and causing vulnerability to adverse outcomes. Susceptibility to stressors is influenced by biological, behavioral, environmental, and social risk factors, with the main consequence being an increased risk for multiple adverse health outcomes, including disability, morbidity, falls, hospitalization, institutionalization, and death. However, frailty is a dynamic and not an irreversible process; it seems preventable, may be delayed, or reversed. Our understanding of frailty has markedly improved over the last five years, yet there are many issues yet to be resolved.
FrailSafe aims to better understand frailty and its relation to co-morbidities; to identify quantitative and qualitative measures of frailty through advanced data mining approaches on multiparametric data and use them to predict short and long-term outcome and risk of frailty; to develop real life sensing (physical, cognitive, psychological, social) and intervention (guidelines, real-time feedback, AR serious games) platform offering physiological reserve and external challenges; to provide a digital patient model of frailty sensitive to several dynamic parameters, including physiological, behavioural and contextual; this model being the key for developing and testing pharmaceutical and non-pharmaceutical interventions; to create “prevent-frailty” evidence-based recommendations for the elderly; to strengthen the motor, cognitive, and other “anti-frailty” activities through the delivery of personalised treatment programmes, monitoring alerts, guidance and education; and to achieve all with a safe, unobtrusive and acceptable system for the ageing population while reducing the cost of health care systems.

Aufforderung zur Vorschlagseinreichung

H2020-PHC-2014-2015

Andere Projekte für diesen Aufruf anzeigen

Unterauftrag

H2020-PHC-2015-single-stage

Koordinator

PANEPISTIMIO PATRON
Netto-EU-Beitrag
€ 831 000,00
Adresse
UNIVERSITY CAMPUS RIO PATRAS
265 04 Rio Patras
Griechenland

Auf der Karte ansehen

Region
Κεντρική Ελλάδα Δυτική Ελλάδα Αχαΐα
Aktivitätstyp
Higher or Secondary Education Establishments
Links
Gesamtkosten
€ 831 000,00

Beteiligte (8)