Objetivo Transducing information to and from biological environments is essential for bioresearch, neuroscience and healthcare. There has been recent focus on using organic semiconductors to interface the living world, since their structural similarity to bio-macromolecules strongly favours their biological integration. Either water-soluble conjugated polyelectrolytes are dissolved in the biological medium, or solid-state organic thin films are incorporated into bioelectronic devices. Proof-of-concept of versatile applications has been demonstrated – sensing, neural stimulation, transduction of brain activity, and photo-stimulation of cells. However, progress in the organic biosensing and bioelectronics field is limited by poor understanding of the underlying fundamental working principles. Given the complexity of the disordered, hybrid solid-liquid systems of interest, gaining mechanistic knowledge presents a considerable scientific challenge. The objective of OSIRIS is to overcome this challenge with a high-end spectroscopic approach, at present essentially missing from the field. We will address: 1) The nature of the interface at molecular and macroscopic level (assembly of polyelectrolytes with bio-molecules, interfacial properties of immersed organic thin films). 2) How the optoelectronics of organic semiconductors are affected upon exposure to aqueous environments containing electrolytes, biomolecules and cells. 3) How information is transduced across the interface (optical signals, thermal effects, charge transfer, electric fields, interplay of electronic/ionic transport). Via spectroscopy, we will target relevant optoelectronic processes with ultrafast time-resolution, structurally characterize the solid-liquid interface using non-linear sum-frequency generation, exploit Stark shifts related to interfacial fields, determine nanoscale charge mobility using terahertz spectroscopy in attenuated total reflection geometry, and simultaneously measure ionic transport. Ámbito científico natural sciencesphysical scienceselectromagnetism and electronicsoptoelectronicsnatural sciencesbiological sciencesbiochemistrybiomoleculesengineering and technologymaterials engineeringcoating and filmsnatural sciencesphysical scienceselectromagnetism and electronicssemiconductivitynatural sciencesphysical sciencesopticsspectroscopy Programa(s) H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) Main Programme Tema(s) ERC-2016-STG - ERC Starting Grant Convocatoria de propuestas ERC-2016-STG Consulte otros proyectos de esta convocatoria Régimen de financiación ERC-STG - Starting Grant Institución de acogida UNIVERSITAET BERN Aportación neta de la UEn € 1 498 275,00 Dirección HOCHSCHULSTRASSE 6 3012 Bern Suiza Ver en el mapa Región Schweiz/Suisse/Svizzera Espace Mittelland Bern / Berne Tipo de actividad Higher or Secondary Education Establishments Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Participación en los programas de I+D de la UE Opens in new window Red de colaboración de HORIZON Opens in new window Coste total € 1 498 275,00 Beneficiarios (2) Ordenar alfabéticamente Ordenar por aportación neta de la UE Ampliar todo Contraer todo UNIVERSITAET BERN Suiza Aportación neta de la UEn € 1 498 275,00 Dirección HOCHSCHULSTRASSE 6 3012 Bern Ver en el mapa Región Schweiz/Suisse/Svizzera Espace Mittelland Bern / Berne Tipo de actividad Higher or Secondary Education Establishments Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Participación en los programas de I+D de la UE Opens in new window Red de colaboración de HORIZON Opens in new window Coste total € 1 498 275,00 UNIVERSITE DE FRIBOURG La participación finalizó Suiza Aportación neta de la UEn € 0,00 Dirección AVENUE DE L EUROPE 20 1700 Fribourg Ver en el mapa Región Schweiz/Suisse/Svizzera Espace Mittelland Fribourg / Freiburg Tipo de actividad Higher or Secondary Education Establishments Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Participación en los programas de I+D de la UE Opens in new window Red de colaboración de HORIZON Opens in new window Coste total Sin datos