Myelin at the crossroads of Development and Disease

Project Information

Myel-IN-Crisis

Grant agreement ID: 789054

DOI

10.3030/789054

Project closed

EC signature date 8 August 2018

Start date 1 October 2018

End date 31 March 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 500 000,00

EU contribution

€ 2 500 000,00

Coordinated by

THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
United Kingdom

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (8)

Evidence for glutamine synthetase function in mouse spinal cord oligodendrocytes

Author(s): Lucile Ben Haim, Lucas Schirmer, Amel Zulji, Khalida Sabeur, Brice Tiret, Matthieu Ribon, Sandra Chang, Wouter H. Lamers, Séverine Boillée, Myriam M. Chaumeil, David H. Rowitch
Published in: Glia, Issue 69/12, 2021, Page(s) 2812-2827, ISSN 0894-1491
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/glia.24071

Neuronal vulnerability and multilineage diversity in multiple sclerosis

Author(s): Lucas Schirmer, Dmitry Velmeshev, Staffan Holmqvist, Max Kaufmann, Sebastian Werneburg, Diane Jung, Stephanie Vistnes, John H. Stockley, Adam Young, Maike Steindel, Brian Tung, Nitasha Goyal, Aparna Bhaduri, Simone Mayer, Jan Broder Engler, Omer A. Bayraktar, Robin J. M. Franklin, Maximilian Haeussler, Richard Reynolds, Dorothy P. Schafer, Manuel A. Friese, Lawrence R. Shiow, Arnold R. Kriegstein,
Published in: Nature, Issue 573/7772, 2019, Page(s) 75-82, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-019-1404-z

Oligodendrocyte Slc48a1 (Hrg1) encodes a functional heme transporter required for myelin integrity

Author(s): John H. Stockley, Adrien M. Vaquie, Zhaoyang Xu, Theresa Bartels, Gregory D. Jordan, Staffan Holmqvist, Simon Gunter, Guy Lam, Daniel Yamamoto, Rini H. Pek, Ian G. Chambers, Andrew S. Rock, Myfanwy Hill, Chao Zhao, Scott Dillon, Robin J. M. Franklin, Rosemary O'Connor, David M. Bodine, Iqbal Hamza, David H. Rowitch
Published in: Glia, Issue 73, 2024, Page(s) 399-421, ISSN 0894-1491
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/glia.24641

Generation of functional human oligodendrocytes from dermal fibroblasts by direct lineage conversion

Author(s): Koji Tanabe, Hiroko Nobuta, Nan Yang, Cheen Euong Ang, Philip Huie, Sacha Jordan, Michael C. Oldham, David H. Rowitch, Marius Wernig
Published in: Development, Issue 149, 2022, ISSN 0950-1991
Publisher: The Company of Biologists Ltd.
DOI: 10.1242/dev.199723

Wnt-Dependent Oligodendroglial-Endothelial Interactions Regulate White Matter Vascularization and Attenuate Injury

Author(s): Manideep Chavali, Maria José Ulloa-Navas, Pedro Pérez-Borredá, Jose Manuel Garcia-Verdugo, Patrick S. McQuillen, Eric J. Huang, David H. Rowitch
Published in: Neuron, Issue 108/6, 2020, Page(s) 1130-1145.e5, ISSN 0896-6273
Publisher: Cell Press
DOI: 10.1016/j.neuron.2020.09.033

Oligodendrocyte Death in Pelizaeus-Merzbacher Disease Is Rescued by Iron Chelation

Author(s): Hiroko Nobuta, Nan Yang, Yi Han Ng, Samuele G. Marro, Khalida Sabeur, Manideep Chavali, John H. Stockley, David W. Killilea, Patrick B. Walter, Chao Zhao, Philip Huie, Steven A. Goldman, Arnold R. Kriegstein, Robin J.M. Franklin, David H. Rowitch, Marius Wernig
Published in: Cell Stem Cell, Issue 25/4, 2019, Page(s) 531-541.e6, ISSN 1934-5909
Publisher: Cell Press
DOI: 10.1016/j.stem.2019.09.003

Astrocyte layers in the mammalian cerebral cortex revealed by a single-cell in situ transcriptomic map

Author(s): Omer Ali Bayraktar, Theresa Bartels, Staffan Holmqvist, Vitalii Kleshchevnikov, Araks Martirosyan, Damon Polioudakis, Lucile Ben Haim, Adam M. H. Young, Mykhailo Y. Batiuk, Kirti Prakash, Alexander Brown, Kenny Roberts, Mercedes F. Paredes, Riki Kawaguchi, John H. Stockley, Khalida Sabeur, Sandra M. Chang, Eric Huang, Peter Hutchinson, Erik M. Ullian, Martin Hemberg, Giovanni Coppola, Matthew G. H
Published in: Nature Neuroscience, Issue 23/4, 2020, Page(s) 500-509, ISSN 1097-6256
Publisher: Nature Publishing Group
DOI: 10.1038/s41593-020-0602-1

Myeloid cell interferon secretion restricts Zika flavivirus infection of developing and malignant human neural progenitor cells

Author(s): Harry Bulstrode, Gemma C. Girdler, Tannia Gracia, Alexander Aivazidis, Ilias Moutsopoulos, Adam M.H. Young, John Hancock, Xiaoling He, Katherine Ridley, Zhaoyang Xu, John H. Stockley, John Finlay, Clement Hallou, Teodoro Fajardo, Daniel M. Fountain, Stijn van Dongen, Alexis Joannides, Robert Morris, Richard Mair, Colin Watts, Thomas Santarius, Stephen J. Price, Peter J.A. Hutchinson, Emma J. Hodso
Published in: Neuron, Issue 110, 2024, Page(s) 3936-3951.e10, ISSN 0896-6273
Publisher: Cell Press
DOI: 10.1016/j.neuron.2022.09.002