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CORDIS - Resultados de investigaciones de la UE
CORDIS

Collaboration for Prevention and Treatment of MDR Bacterial Infections

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

Launch of biorepository and database (se abrirá en una nueva ventana)

Launch of biorepository and database including five candidate bacterial reference strains suitable for preclinical testing

Implementation of quality standards, software and infrastructure to support data integration activities for Pillar A studies (se abrirá en una nueva ventana)

Implementation of quality standards, software and infrastructure to support data integration activities for Pillar A studies. Documentation describing the IT solution for Pillar A related data integration.

Establish data management plan (se abrirá en una nueva ventana)

A data management plan for COMBINE will be formulated and agreed with the partners and consortia management The COMBINE plan will also form the basis for project data management plans within individual Pillar B and Pillar C projects and will cover GDPR FAIR data provenance ALCOA and data integration aspectThe following ethics issues to be addressed in the Data Management Plan DMP 1 The members of the consortium must confirm that they have appointed Data Protection Officers DPOs and the contact details of the DPO are made available to all data subjects involved in the research For the members of the consortium not required to appoint a DPO under the General Data Protection Regulation a detailed data protection policy for the project must be elaborated and kept on file It must be provided to IMI JU upon request2 A description of the technical and organisational measures that will be implemented to safeguard the rights and freedoms of the data subjectsresearch participants must be provided A description of the security measures that will be implemented to prevent unauthorised access to personal data or the equipment used for processing must be provided3 The applicants must clarify what the countries as yet unknown are and what data will be imported from them to the EU 4 For the personal data obtained from the nonEU countries the applicants must confirm that such transfers comply with the laws of the country in which the data was collected5 Detailed information on the informed consent procedures in regard to data processing must be provided prior to the start of the relevant research activity6 The applicants must confirm that the specific informed consent forms and information sheets for data processing in language and terms intelligible to the participants are kept on file They must be provided to IMI JU upon request7 In case of further processing of previously collected personal data an explicit confirmation that the applicants have lawful basis for data processing and that the appropriate technical and organisational measures are in place to safeguard the rights of the data subjects must be provided Relevant authorisations must be obtained and kept on file The documents must be provided to IMI JU upon request

Review of guidelines and literature around the development of monoclonal antibodies against AMR pathogens (se abrirá en una nueva ventana)
Review of guidelines and literature (se abrirá en una nueva ventana)

Review of guidelines and literature on vaccines with input from expert workshop on integrated data analysis

Implementation of quality standards, software and infrastructure to support data integration activities for data arriving from Pillar B and C projects (se abrirá en una nueva ventana)

Implementation of quality standards software and infrastructure to support data integration activities for data arriving from Pillar B and C projects Documentation describing the IT solution for Pillar B and C related data integration

Updated data management plan (se abrirá en una nueva ventana)

Prepare an updated data management plan taking into account the experience gained in the project implementation period

Report on relationships between pre-clinical targets and clinical outcomes (se abrirá en una nueva ventana)

Report on relationships between preclinical targets and clinical outcomes

Charter for the Data Management Group (se abrirá en una nueva ventana)

Document describing membership, roles, planned activities and responsibilities of the cross-accelerator DMG. All Data Management Champions will subscribe to the charter.

Publicaciones

Challenges for Clinical Development of Vaccines for Prevention of Hospital-Acquired Bacterial Infections (se abrirá en una nueva ventana)

Autores: Isabelle Bekeredjian-Ding
Publicado en: Frontiers in Immunology, Edición 11, 2020, Página(s) (Volume 11, Article 1755), ISSN 1664-3224
Editor: Frontiers
DOI: 10.3389/fimmu.2020.01755

Expert Workshop Summary: Advancing towards a standardized murine model to evaluate treatments for AMR lung infections (se abrirá en una nueva ventana)

Autores: Arrazuria R, Kerscher B, Huber KE, Hoover JL, Lundberg CV, Hansen JU, Sordello S, Renard S, Aranzana-Climent V, Hughes D, Gribbon P, Friberg LE, Bekeredjian-Ding I
Publicado en: Front Microbiol, 2022, ISSN 1664-302X
Editor: Frontiers Media
DOI: 10.3389/fmicb.2022.988725

Variability of murine bacterial pneumonia models used to evaluate antimicrobial agents (se abrirá en una nueva ventana)

Autores: Arrazuria R, Kerscher B, Huber KE, Hoover JL, Lundberg CV, Hansen JU, Sordello S, Renard S, Aranzana-Climent V, Hughes D, Gribbon P, Friberg LE, Bekeredjian-Ding I
Publicado en: Front Microbiol, 2022, ISSN 1664-302X
Editor: Frontiers Media
DOI: 10.3389/fmicb.2022.988728

The AMR Accelerator: from individual organizations to efficient antibiotic development partnerships (se abrirá en una nueva ventana)

Autores: Josepine Fernow, Marie Olliver, William Couet, Sophie Lagrange, Meindert H. Lamers, Ole F. Olesen, Kristina Orrling, Michel Pieren, Derek J. Sloan, Juan José Vaquero, Timothy J. Miles, Anders Karlén
Publicado en: Nature Reviews Drug Discovery, 2024, ISSN 1474-1776
Editor: Nature Publishing Group
DOI: 10.1038/d41573-024-00138-9

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