Fast optoacoustic mesoscopy, using the skin as a window for therapeutic monitoring of local and systemic disease.

Informazioni relative al progetto

WINTHER

ID dell’accordo di sovvenzione: 871763

DOI

10.3030/871763

Progetto chiuso

Data della firma CE 5 Dicembre 2019

Data di avvio 1 Gennaio 2020

Data di completamento 31 Dicembre 2024

Finanziato da

• INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Information and Communication Technologies (ICT)

Costo totale

€ 5 111 203,75

Contributo UE

€ 4 292 170,00

Coordinato da

TECHNISCHE UNIVERSITAET MUENCHEN
Germany

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Websites, patent fillings, videos etc. (3)

Public promotion leaflet and F-RSOM postcard

Public awareness documents containing EU Horizon 2020 WINTHER and partner logos and impressive images generated by FRSOM and explanation of WINTHER goals achievements and impact

Program, presentation slides and summarized findings of dissemination workshop

Report on talks (slides), major findings, workshop achievements and feedback.

Project web site

Creation of a project logo and web site comprising a public domain and a password-protected area. The public area will serve as reference point for the public and industry (project description, accomplishments, activities), while the internal use-only area will provide secure data and information exchange for the consortium partners (containing the management and quality manual, and a data and document repository and description of WINTHER goals).

Documents, reports (1)

Final dissemination and exploitation report and business plan

Final report on IPR search, WINTHER innovation and a plan of promising markers and selection of the technology based on WINTHER results and experience.

Pubblicazioni

Peer reviewed articles (11)

Enabling precision monitoring of psoriasis treatment by optoacoustic mesoscopy

Autori: Hindelang, B., Nau, T., Englert, L., Berezhnoi, A., Lauffer, F., Darsow, U., Biedermann, T., Eyerich, K., Aguirre, J., and Ntziachristos, V.
Pubblicato in: Science Translational Medicine, 2022, ISSN 1946-6234
Editore: American Association for the Advancement of Science
DOI: 10.1126/scitranslmed.abm8059

Machine learning analysis of human skin by optoacoustic mesoscopy for automated extraction of psoriasis and aging biomarkers

Autori: Hailong He, Johannes C. Paetzold, Nils Börner, Erik Riedel, Stefan Gerl, Simon Schneider, Chiara Fisher, Ivan Ezhov, Suprosanna Shit, Hongwei Li, Daniel Rückert, Juan Aguirre, Tilo Biedermann, Ulf Darsow, Bjoern Menze and Vasilis Ntziachristos.
Pubblicato in: IEEE Transactions on Medical Imaging, 2024, ISSN 1558-254X
Editore: IEEE Xplore
DOI: 10.1109/tmi.2024.3356180

Raster-scanning optoacoustic mesoscopy biomarkers for atopic dermatitis skin lesions

Autori: Nau, T., Schönmann, C., Hindelang, B., Riobo, L., Doll, A., Schneider, S., Englert, L., He, H., Biedermann, T., Darsow, U., Lauffer, F., Ntziachristos, V., and Aguirre, J.
Pubblicato in: Photoacoustics, 2023, ISSN 2213-5979
Editore: Elsevier GmbH
DOI: 10.1016/j.pacs.2023.100513

Optoacoustic imaging in endocrinology and metabolism

Autori: Karlas, A., Pleitez, M.A., Aguirre, J., and Ntziachristos, N.
Pubblicato in: Nature Reviews Endocrinology, Numero 17(6), 2021, Pagina/e 323-335, ISSN 1759-5037
Editore: Springer Nature
DOI: 10.1038/s41574-021-00482-5

Opening a window to skin biomarkers for diabetes stage with optoacoustic mesoscopy

Autori: Hailong He; Nikolina-Alexia Fasoula; Angelos Karlas; Murad Omar; Juan Aguirre; Jessica Lutz; Michael Kallmayer; Martin Füchtenbusch; Hans-Henning Eckstein; Annette Ziegler; Vasilis Ntziachristos
Pubblicato in: Light: Science & Applications, Vol 12, Iss 1, Pp 1-15 (2023), Numero 4, 2023, ISSN 2047-7538
Editore: Nature
DOI: 10.1038/s41377-023-01275-3

Quality control in clinical raster-scan optoacoustic mesoscopy.

Autori: Hailong He, Chiara Fischer, Ulf Darsow, Juan Aguirre, Vasilis Ntziachristos
Pubblicato in: Photoacoustics, 2023, ISSN 2213-5979
Editore: Elsevier GmbH
DOI: 10.1016/j.pacs.2023.100582

Fast raster-scan optoacoustic mesoscopy enables assessment of human melanoma microvasculature in vivo

Autori: He, H., Schönmann, C., Schwarz, M., Hindelang, B., Bereznhoi, A., Steimle-Grauer, A., Darsow, U., Aguirre, J., and Ntziachristos, V.
Pubblicato in: Nature Communications, 2022, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-022-30471-9

Fast 3D Optoacoustic Mesoscopy of Neuromelanin Through Entire Human Midbrain Organoids at Single-Cell Resolution

Autori: Englert, L., Lacalle-Aurioles, M., Mohamed, N.-V., Lépine, P., Mathur, M., Ntziachristos, V., Durcan T.M. and Aguirre, J.
Pubblicato in: Laser and Photonics Reviews, 2023, ISSN 1863-8880
Editore: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/lpor.202300443

Enabling the autofocus approach for parameter optimization in planar measurement geometry clinical optoacoustic imaging

Autori: Englert, L., Riobo, L., Schönmann, C., Ntziachristos, V., and Aguirre, J.
Pubblicato in: Journal of Biophotonics, 2022, ISSN 1864-063X
Editore: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/jbio.202200032

Dermal features derived from optoacoustic tomograms via machine learning correlate microangiopathy phenotypes with diabetes stage.

Autori: Angelos Karlas, Nikoletta Katsouli, Nikolina-Alexia Fasoula, Michail Bariotakis, Nikolaos-Kosmas Chlis, Murad Omar, Hailong He, Dimitrios Iakovakis, Christoph Schäffer, Michael Kallmayer, Martin Füchtenbusch, Annette Ziegler, Hans-Henning Eckstein, Leontios Hadjileontiadis , Vasilis Ntziachristos.
Pubblicato in: Nature Biomedical Engineering, 2023, Pagina/e 1667–1682, ISSN 2157-846X
Editore: Nature
DOI: 10.1038/s41551-023-01151-w

A primer on current status and future opportunities of clinical optoacoustic imaging

Autori: Ferdinand Knieling, Serene Lee, Vasilis Ntziachristos
Pubblicato in: npj Imaging, 2025, ISSN 2948-197X
Editore: Springer Nature
DOI: 10.1038/s44303-024-00065-9