Infection detection in human semen

Información del proyecto

DetectInMen

Identificador del acuerdo de subvención: 876705

DOI

10.3030/876705

Proyecto cerrado

Fecha de la firma de la CE 21 Julio 2019

Fecha de inicio 1 Julio 2019

Fecha de finalización 31 Diciembre 2019

Financiado con arreglo a

• INDUSTRIAL LEADERSHIP - Innovation In SMEs

Coste total

€ 71 429,00

Aportación de la UE

€ 50 000,00

Coordinado por

FABTECH ELSO BIOTECHNOLOGIAI AUTOMATIZACIO KORLATOLT FELELOSSEGU TARSASAG
Hungary

Periodic Reporting for period 1 - DetectInMen (Infection detection in human semen)

Período documentado: 2019-07-01 hasta 2019-12-31

Resumen del contexto y de los objetivos generales del proyecto

Male infertility crises are observed in developed countries world-wide, with serious socio-economic implications. One possible reason is asymptotic anaerobe bacterial infection, which is only detectable by currently applied analytical methods after anaerobe sampling. This method, however, cannot be integrated to clinical practice. We developed a highly reliable bacterial infection detection method (DetectInMen) for human semen. Our method requires no cell culturing, can analyse samples without pre-conditioning, detects anaerobic bacteria species without anaerobic sampling and processing.

Trabajo realizado desde el comienzo del proyecto hasta el final del período abarcado por el informe y los principales resultados hasta la fecha

We carried out a feasibility study examining both technical feasibility and business viability of the project. We made preparation for clinical study. We made a clinical trial design, determined the gold standards and outlined ethical considerations for the clinical study. We selected some potential clinics. In addition, we validated our business assumptions by structured interviews with men’s fertility specialists (andrologists) and medical laboratory service providers. Furthermore, we performed a risk assessment and suggested mitigations for the risks. We have also completed our business plan based on business model canvas, including our company strategy, commercial model, financial scale-up plan, organisational growth plan. We also made an analysis on IP protection, regulatory issues and freedom to operate. Finally, we made a detailed plan for a further grant in the EIC-Accelerator Pilot including both grant and equity component.

Avances que van más allá del estado de la técnica e impacto potencial esperado (incluida la repercusión socioeconómica y las implicaciones sociales más amplias del proyecto hasta la fecha)

The project is based on a ground-breaking innovation, since no current method can detect anaerobic bacterial infection in human semen by the applied clinical routine. Application of DetectInMen method will increase success of therapy for infertile and subfertile men: double the number of within-1-year successful fertility treatments, decreasing the number of unsuccessful therapies by 1/3. It may also reduce the need for assisted reproduction, decreasing the high costs for both the patient and health service. The success of this project will also impact on our company growth.