Innovative tools to study the impact and mode of action of micro and nanoplastics on human health: towards a knowledge base for risk assessment

CORDIS fournit des liens vers les livrables publics et les publications des projets HORIZON.

Les liens vers les livrables et les publications des projets du 7e PC, ainsi que les liens vers certains types de résultats spécifiques tels que les jeux de données et les logiciels, sont récupérés dynamiquement sur OpenAIRE .

Livrables

Validated in vitro and in silico models to quantify in vivo bioavailability of pristine as compared to digested MNPLs, and of associated harmful contaminants and toxic additives

In vitro and PBK models to assess MNPLs bioavailability

Legal & Ethics Management Handbook

Ethics manual

External human exposure with MNPLs in targeted air, food, and water samples

Report on MNPLs human external exposure

Communication and Dissemination activities and impact assessment

Detail of the communication and dissemination action

Integrated analysis and usability of the novel candidate biomarkers for long-term MNPLs induced effects

Report including compiled data on novel biomarkers of MNPLs long-term exposure

Validated sampling strategies, analytical workflows, and quality assurance protocols to be applied for the determination and characterization of MNPLs in targeted environmental and food samples

Report on the experimental procedure to characterize huamn external MNPLs exposure

Protocol of synthesis of reference MNPLs together with their respective characterization

Report containing the datasheets of the reference MNPLs of the project

Communication and Dissemination Plan

Detail of the communication and dissemination action

Joint policy brief 1

The Cluster policy briefs will be defined by the cluster partners

Food design, treatments, and type of packaging and storage conditions to evaluate their effect on microplastics concentrations throughout time

Report on the MNPLs burden and modulatory factors on food

Validated PBK models to translate in vitro toxicity data on MNPLs to in vivo dose response curves that enable HRA

MNPLs in vitro to in vivo correlation through PBK modelling

Toxicokinetic and toxicodynamic profiles of MNPLs in Drosophila

MNPLs in vivo effects using Drosophila as a model

Validated 3D in vitro tissue model of human alveoli to quantify the toxicity of MNPLs and of associated harmful contaminants and toxic additives, following exposure on the air-liquid interface

Report related to the in vitro effects of MNPLs on the RT

Data platform and Data management report

Report containing PLASTICHEAL data platform information

Project Management Handbook

Management strategy of the project

Joint policy brief 2

The Cluster policy briefs will be defined by the cluster partners.

Common dissemination and communication strategy for the cluster

Cluster communication and dissemination plan will take into account projects individual plans shared This report will be updated during clusters life

Toxicokinetic and toxicodynamic profiles of MNPLs after ingestion or aspiration in mice

Report related to the MNPLs impact using mice as a in vivo model

Cluster brochure
Validated in vitro models to quantify the effect of gastrointestinal digestion on MNPLs bioavailability and toxicity and of associated harmful contaminants and toxic additives

Report related to the in vitro models useful to study MNPLs impact on the GIT

Stakeholder and gap analysis including database on projects and regulatory initiatives

Report gathering all conclusions from the initial round of dialogue with regulatory bodies

Standard operating procedures for the application of analytical methods to the detection and measurement of MNPLs in biological tissues

SOPs to study MNPLs in tissue samples

Transforming potential of MNPLs

Report on the carcinogenic potential of MNPL under in vitro long-term exposure settings

MNPLs effect on transcriptome, secretome and inflammasome activation

Report on the omics effects of MNPLs in the immune system

New HRA framework and examples of uses

Report containing the HRA framework of the project

MNPLs genotoxicity, toxicity, oxidative stress, cell cycle and maturation of immune

A report including the MNPLs impact on the immune system

Joint policy brief 3

The Cluster policy briefs will be defined by the cluster partners.

Genotoxic, and innovative biomarkers of MNPLs-induced long-term effects, including modulatory factors

Report including MNPLs effects after long-term in vitro exposures

Data Management Plan

Report containing the management strategy of the project

Project website

Project website in full operation

Cluster web portal and visual identity

The Cluster webportal will be updated regularly.

Publications

Toxicity of Polystyrene Particles to Mice and in Vitro Models of Intestinal Cells, Both Healthy and with Genetic Susceptibility to Crohn's Disease

Auteurs: Manon Dussol, Sandrine Ménard, Maeva Boulée, Vérane Bard, Melvin Airaud, Daphna Fenel, Christine Moriscot, Frederick Barreau, Marie Carrière
Publié dans: Journal of Hazardous Materials, 2024, ISSN 0304-3894
Éditeur: Elsevier BV
DOI: 10.2139/ssrn.4964764

Environmental Pollutants: Micro and Nanoplastics in Immunity and Respiratory Infections

Auteurs: Iris Romero-Andrada, Alicia Lacoma, Alba Hernández, José Domínguez
Publié dans: Archivos de Bronconeumología, Numéro Volume 59, Numéro 11, 2023, Page(s) 709-711, ISSN 0300-2896
Éditeur: Ediciones Doyma S.A.
DOI: 10.1016/j.arbres.2023.07.005

Evaluation of the toxicity, alveolar cell accumulation and clearance of PET and PS nanoplastics in mouse lungs

Auteurs: Thomas Loret, Sonja Holme, Aswin Kuttykattil, Aliro Villacorta, Adriana Rodríguez-Garraus, Tom Venus, Irina Irina Estrela-Lopis, Julia Catalán, Ricard Marcos, Alba Hernández, Cyrill Bussy
Publié dans: Annals of Work Exposures and Health. Abstracts from the 2023 Inhaled Particles and NanOEH conference, Numéro Volume 67, Numéro Supplement_1, 2023, Page(s) i53–i54, ISSN 2398-7316
Éditeur: Oxford University Press
DOI: 10.1093/annweh/wxac087.130

To be or not to be a nanomaterial

Auteurs: Steffen Foss Hansen*, Maria Bille Nielsen, Oliver Foss Hessner Hansen, Lauge Peter Westergaard Clausen, Lars Michael Skjolding, Anders Baun, Rickard Arvidsson
Publié dans: Journal of NanoParticle Research, Numéro Volume 24, article number 235, 2022, ISSN 1388-0764
Éditeur: Kluwer Academic Publishers
DOI: 10.1007/s11051-022-05613-1

A new source of representative secondary PET nanoplastics. Obtention, characterization, and hazard evaluation

Auteurs: Villacorta A., L. Rubio, M. Alaraby, M. Lopez-Mesas, V. Fuentes-Cebrian, O.H. Moriones, R. Marcos, A. Hernández
Publié dans: Spanish Journal of Environmental Mutagenesis and Genomics, Numéro Vol. 27 No. 1 (2023), 2023
Éditeur: Spanish Environmental Mutagenesis and Genomics Society

Degradation of PLA and PET particles exposed to UV light and toxicological effects on human intestinalcell models

Auteurs: Vérane Bard, Thierry Douki, Maeva Boulée, Aliro Villacorta, Alba Hernández, Ricard Marcos, Marie Carriere
Publié dans: 20th Congress of the European Society for Photobiology, 2023, Page(s) 386
Éditeur: European Society for Photobiology

Oncogenic effects caused by in vitro long-term co-exposure to polystyrene nanoparticles and arsenic

Auteurs: Barguilla I, J. Domenech, R. Marcos, A. Hernández
Publié dans: Spanish Journal of Environmental Mutagenesis and Genomics, Numéro 25 - XXV Meeting of the Spanish Environmental Mutagenesis and Genomics Society -, 2021, Page(s) 17, ISSN 2952-1742
Éditeur: Spanish Environmental Mutagenesis and Genomics Society (SEMA)

Modeling human-derived in vitro barriers for environmental toxicology

Auteurs: García-Rodríguez, A., Martín Pérez, J., Rubio, L., Banaei, G., Marcos, R., & Hernández, A.
Publié dans: Spanish Journal of Environmental Mutagenesis and Genomics, 27(1), 27, Numéro Vol. 27 No. 1 (2023), 2023
Éditeur: Spanish Environmental Mutagenesis and Genomics Society

Drosophila melanogaster as bioindicator of microbiome dysfunction

Auteurs: García-Rodríguez, A., Martín Pérez, J., Rocabert, A., Pareres, L., Alaraby, M., Marcos, R., & Hernández, A.
Publié dans: Spanish Journal of Environmental Mutagenesis and Genomics, 27(1), 165, Numéro Vol. 27 No. 1 (2023), 2023
Éditeur: Spanish Environmental Mutagenesis and Genomics Society

Stem cells as unique models to study long-term effects triggered by micro- and nanoplastic exposure: a focus on cell transformation and differentiation

Auteurs: Barguilla, I., Guyot, B., & Maguer-Satta, V.
Publié dans: Spanish Journal of Environmental Mutagenesis and Genomics, 27(1), 141, Numéro Vol. 27 No. 1 (2023), 2023
Éditeur: Spanish Environmental Mutagenesis and Genomics Society

Effects of the in vitro digestive process on the toxicological profile of polystyrene nanoplastics in different human hematopoietic cell lines

Auteurs: Vela L., J. Domenech, R. Marcos. A. Hernández
Publié dans: Spanish Journal of Environmental Mutagenesis and Genomics, Numéro 25 - XXV Meeting of the Spanish Environmental Mutagenesis and Genomics Society -, 2021, Page(s) 20, ISSN 2952-1742
Éditeur: Spanish Environmental Mutagenesis and Genomics Society (SEMA)

Hazard assessment of different-sized polystyrene nanoplastics in a human B-lymphoblastoid cell line

Auteurs: Tavakolpournegari, A., Annangi, B., Villacorta, A., Banaei, G., Martin, J., Pastor, S., Marcos, R., & Hernández, A.
Publié dans: Spanish Journal of Environmental Mutagenesis and Genomics, 27(1), 157, Numéro Vol. 27 No. 1 (2023), 2023
Éditeur: Spanish Environmental Mutagenesis and Genomics Society

Polystyrene nanoplastics: Surface- and size-dependent effects on human primary endothelial cells

Auteurs: Martín J., A. García, R. Marcos, A. Hernández
Publié dans: Spanish Journal of Environmental Mutagenesis and Genomics, Numéro 27(1), 166, 2023, ISSN 2952-1742
Éditeur: Spanish Environmental Mutagenesis and Genomics Society

In vitro cell transforming capacity of different types of nano-plastics

Auteurs: Domenech, J., Villacorta, A., Ferrer, J. F., Llorens, R., Marcos, R., Hernández, A., & Catalán, J.
Publié dans: Spanish Journal of Environmental Mutagenesis and Genomics, 27(1), 38, Numéro Vol. 27 No. 1 (2023), 2023
Éditeur: Spanish Environmental Mutagenesis and Genomics Society

Can the digestion of polystyrene nanoplastics modulate their toxicological profile? Studies in three different human hematopoietic cell lines -

Auteurs: Vela L., A. Villacorta, L. Rubio, R. Marcos, A. Hernández
Publié dans: Spanish Journal of Environmental Mutagenesis and Genomics, Numéro 26 - XXVI Meeting of the Spanish Environmental Mutagenesis and Genomics Society, 2022, Page(s) 26, ISSN 2952-1742
Éditeur: Spanish Environmental Mutagenesis and Genomics Society (SEMA)

Human white blood cells after ex vivo exposure to polystyrene nanoplastics

Auteurs: Ballesteros S., J. Domenech, I. Barguilla, C. Cortés, R. Marcos, , A. Hernández
Publié dans: Spanish Journal of Environmental Mutagenesis and Genomics, Numéro Vol. 25 No. 1 (2021), 2021, ISSN 2952-1742
Éditeur: Spanish Environmental Mutagenesis and Genomics Society

A new source of representative secondary PET nanoplastics. Obtention, characterization, and hazard evaluation

Auteurs: A. Villacorta L. Rubio M. Alaraby M. Lopez-Mesas V. Fuentes-Cebrián O. H. Moriones R. Marcos A. Hernández
Publié dans: Spanish Journal of Environmental Mutagenesis and Genomics, 26(1), 31, Numéro Vol. 26 No. 1 (2022), 2022
Éditeur: Spanish Environmental Mutagenesis and Genomics Society

Interactions of in-house made polyethylene terephthalate nanoparticles with human hematopoietic cell lines as an improved model for assessing the health risk of nanoplastics

Auteurs: Villacorta A., J. Domenech, M. Alaraby, L. Vela, A. Tavakolpournegari, R. Marcos, A. Hernández
Publié dans: Spanish Journal of Environmental Mutagenesis and Genomics, Numéro 25 - XXV Meeting of the Spanish Environmental Mutagenesis and Genomics Society -, 2021, Page(s) 21, ISSN 2952-1742
Éditeur: Spanish Environmental Mutagenesis and Genomics Society (SEMA)

Detection and Quantification of Micro(nano)plastics Release from Photolysis of Surgical Masks

Auteurs: Guyu Peng, Dusan Materic, Thorsten Reemtsma
Publié dans: EGU General Assembly 2023, Numéro EGU23-4226, 2023
Éditeur: EGU
DOI: 10.5194/egusphere-egu23-4226

Particle shape and intrinsic cellular variability shape the responses of macrophages to polystyrene nano and micro particles

Auteurs: Véronique Collin-Faure, Bastien Dalzon, Anaelle Torres, Thierry Rabilloud
Publié dans: 8th International Conference on Health and Safety Numéros for a socially responsible approach to nanomaterials, 2023, Page(s) 61
Éditeur: Nano-Safety Cluster

Understanding the health risks of exposure to micro- & nano-plastics

Auteurs: A. Hernández
Publié dans: Spanish Journal of Environmental Mutagenesis and Genomics, 27(1), 71, Numéro Vol. 27 No. 1 (2023), 2023
Éditeur: Spanish Environmental Mutagenesis and Genomics Society

Sub-lethal in vitro effects of nanoplastics (PET and PS) in primary human nasal epithelial cells (HNEpC) –Role of the autophagy

Auteurs: B. Annangi J. Gutiérrez A. Villacorta R. Marcos A. Hernández
Publié dans: Spanish Journal of Environmental Mutagenesis and Genomics, 26(1), 32, Numéro 26 - XXVI Meeting of the Spanish Environmental Mutagenesis and Genomics Society -, 2022, Page(s) 32, ISSN 2952-1742
Éditeur: Spanish Environmental Mutagenesis and Genomics Society (SEMA)

Long-term effects of PS and PET nanoplastics in lung cell lines

Auteurs: J. Gutiérrez L. Rubio B. Guyot I. Barguilla A. Villacorta A. Bodelón R. Marcos A. Hernández
Publié dans: Spanish Journal of Environmental Mutagenesis and Genomics, 27(1), 164, Numéro Vol. 27 No. 1 (2023), 2023
Éditeur: Spanish Environmental Mutagenesis and Genomics Society

Stemness imbalance and oncogenic effects induced by in vitro chronic exposure to PS and PET nanoplastics in breast progenitor cells

Auteurs: I. Barguilla, B. Guyot and V. Maguer-Satta
Publié dans: Spanish Journal of Environmental Mutagenesis and Genomics, 26(1), 24, Numéro Vol. 26 No. 1 (2022), 2022
Éditeur: Spanish Environmental Mutagenesis and Genomics Society

Deciphering the effects induced by nanoplastics in peripheral blood immune cells

Auteurs: Arribas Arranz, J., Cozzuto, L., Ponomarenko, J., Marcos, R., & Hernández, A.
Publié dans: Spanish Journal of Environmental Mutagenesis and Genomics, 27(1), Numéro Vol. 27 No. 1 (2023), 2023
Éditeur: Spanish Environmental Mutagenesis and Genomics Society

Size-dependent effects of PSNPLs on human hematopoietic cell lines

Auteurs: Tavakolpournegari A., S. Pastor, R. Marcos, A. Hernández
Publié dans: Spanish Journal of Environmental Mutagenesis and Genomics, Numéro 26 - XXVI Meeting of the Spanish Environmental Mutagenesis and Genomics Society, 2022, Page(s) 24, ISSN 2952-1742
Éditeur: Spanish Environmental Mutagenesis and Genomics Society (SEMA)

Interactions of Staphylococcus aureus and polystyrene on 2D minilung infection model

Auteurs: Iris Romero, Irene Chamorro, Alberto Zambrano, Alba Hernández, Jose Domínguez, Alicia Lacoma
Publié dans: Respiratory infections and bronchiectasis, 2025, Page(s) PA2394
Éditeur: European Respiratory Society
DOI: 10.1183/13993003.congress-2024.pa2394

Lung barrier establishment using Calu-3 cell line as an in vitro model to study the pulmonary effects of micro and nanoplastics

Auteurs: Rubio, L., Gutiérrez, J., García-Rodríguez, A., Marcos, R., & Hernández, A.
Publié dans: Spanish Journal of Environmental Mutagenesis and Genomics, 27(1), 173, Numéro Vol. 27 No. 1 (2023), 2023
Éditeur: Spanish Environmental Mutagenesis and Genomics Society

Long-term exposure to nanoplastics alters molecular and functional traits related to the carcinogenic process

Auteurs: Barguilla I, J. Domenech, S. Ballesteros, L. Rubio, R. Marcos, A. Hernández
Publié dans: 2nd Conference on PLASTIC POLLUTION: the Textile Sector, an example towards a sustainable economy (PLASTIC'2022), 2022
Éditeur: IDAEA-CSIC

Polystyrene nanoparticles as carriers of environmental pollutants and its toxicological assessment on in vitro human intestinal Caco-2 cells

Auteurs: Domenech J., C. Cortés , L. Vela, R. Marcos, A. Hernández
Publié dans: Spanish Journal of Environmental Mutagenesis and Genomics, Numéro 25 - XXV Meeting of the Spanish Environmental Mutagenesis and Genomics Society -, 2021, Page(s) 16, ISSN 2952-1742
Éditeur: Spanish Environmental Mutagenesis and Genomics Society (SEMA)

The impact of polystyrene and polyethylene terephthalate nanoplastics on the growth of Staphylococcus aureus,Pseudomonas aeruginosa and M. smegmatis

Auteurs: Nadiia Tytarenko, Iris Romero, Alba Hernández, Jose Domínguez, Alicia Lacoma
Publié dans: The International Journal of Tuberculosis and Lung Disease (IJTLD), Numéro VOLUME 26 NUMBER 11 Supplement 1, 2023, Page(s) S499, ISSN 1027-3719
Éditeur: The International Union Against Tuberculosis and Lung Disease

Long-term exposure to PS and PET nanoparticles in human lung cells

Auteurs: Gutiérrez J., L. Rubio, R. Marcos, A. Hernández
Publié dans: Spanish Journal of Environmental Mutagenesis and Genomics, 26(1), 29, Numéro 26, 2022, ISSN 2952-1742
Éditeur: Spanish Environmental Mutagenesis and Genomics Society

Potential harmful effects of nanoplastics derived from teabags in an in vitro model of the intestinal barrier

Auteurs: Banaei G., A. Villacorta, A. Tavakolpournegari, A. Garcia-Rodriguez, R. Marcos, A. Hernández
Publié dans: Spanish Journal of Environmental Mutagenesis and Genomics, Numéro 26 - XXVI Meeting of the Spanish Environmental Mutagenesis and Genomics Society -, 2022, Page(s) 23, ISSN 2952-1742
Éditeur: Spanish Environmental Mutagenesis and Genomics Society (SEMA)

Potential effects of in vitro digestion on the physicochemical and biological characteristics of polystyrene nanoplastics

Auteurs: Morataya-Reyes, M., Vela, L., Villacorta, A., Venus, T., Pastor, S., Estrela-Lopis, i., Marcos, R., & Hernández, A.
Publié dans: Spanish Journal of Environmental Mutagenesis and Genomics, 27(1), 154, Numéro Vol. 27 No. 1 (2023), 2023
Éditeur: Spanish Environmental Mutagenesis and Genomics Society

Long-term exposure to nanoplastics alters molecular and functional traits related to the carcinogenic process

Auteurs: I. Barguilla, J. Domenech, S. Ballesteros, L. Rubio. R. Marcos, A. Hernández
Publié dans: Spanish Journal of Environmental Mutagenesis and Genomics, 27(1), 143, Numéro Vol. 27 No. 1 (2023), 2023
Éditeur: Spanish Environmental Mutagenesis and Genomics Society

Studying the effects of nanoplastics derived from teabags in an in vitro model of the intestinal epithelium

Auteurs: Banaei, G., Villacorta, A., Tavakolpournegari, A., Garcia-Rodriguez, A., Martin, J., Marcos, R., & Hernández, A.
Publié dans: Spanish Journal of Environmental Mutagenesis and Genomics, 27(1), 158, Numéro Vol. 27 No. 1 (2023), 2023
Éditeur: Spanish Environmental Mutagenesis and Genomics Society

Polystyrene nanoplastics: Surface- and size-dependent effects on human primary endothelial cells

Auteurs: Martín J., A. García, R. Marcos, A. Hernández
Publié dans: Spanish Journal of Environmental Mutagenesis and Genomics, Numéro 26 - XXVI Meeting of the Spanish Environmental Mutagenesis and Genomics Society -, 2022, Page(s) 33, ISSN 2952-1742
Éditeur: Spanish Environmental Mutagenesis and Genomics Society (SEMA)

Toxicity evaluation of micro- and nanoplastic particles, with co-exposure to metal ions on human intestinal models

Auteurs: Vérane Bard, Maeva Boulée, Aliro Villacorta, Sylvie Motellier, Alba Hernandez, Ricard Marcos, Marie Carriere
Publié dans: 8th International Conference on Health and Safety Numéros for a socially responsible approach to nanomaterials, 2023, Page(s) 53
Éditeur: NanoSafe & Nanosafety Cluster

Hazard assessment of polystyrene nanoplastics in primary human nasal epithelial cells, focusing on the autophagic effects

Auteurs: B. Annangi A. Villacorta M. López-Mesas V. Fuentes-Cebrián R. Marcos A. Hernández
Publié dans: Spanish Journal of Environmental Mutagenesis and Genomics, 27(1), 178, Numéro Vol. 27 No. 1 (2023), 2023
Éditeur: Spanish Environmental Mutagenesis and Genomics Society

A Guide for LCA Modelling of Plastics for Safe, Sustainable, and Circular Transition Planning

Auteurs: Heather Margaret Logan*, Steven De Meester, Steffen Foss Hansen, Alexis Laurent, Anders Damgaard
Publié dans: Abstract Book of SETAC Europe 33rd Annual Meeting, 2023, ISSN 2309-8031
Éditeur: Society of Environmental Toxicology and Chemistry - Europe

Preliminary data on the cytotoxic effects of polyethylene terephthalate and polystyrene nanoplastics on Huh-7 hepatocytes

Auteurs: Morataya-Reyes M., A. Villacorta, A. Hernández, R. Marcos
Publié dans: Spanish Journal of Environmental Mutagenesis and Genomics, Numéro Vol. 26 No. 1 (2022), 2022
Éditeur: Spanish Environmental Mutagenesis and Genomics Society

Does size matter? A proteomics-informed comparison of the effects of polystyrene beads of different sizes on macrophages

Auteurs: Bastien Dalzon, Véronique Collin-Faure, Julie Devcic, Hélène Diemer, Sarah Cianférani, Thierry Rabilloud
Publié dans: Environmental Science: Nano, 2022, ISSN 2051-8161
Éditeur: Royal Society of Chemistry
DOI: 10.1039/d2en00214k

In Vitro Approaches to Determine the Potential Carcinogenic Risk of Environmental Pollutants

Auteurs: Irene Barguilla; Veronique Maguer-Satta; Boris Guyot; Susana Pastor; Ricard Marcos; Alba Hernández
Publié dans: International Journal of Molecular Sciences, Numéro 25, 2023, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms24097851

Nanoplastic exposure affects the intestinal microbiota of adult Drosophila flies

Auteurs: Arnau Rocabert, Joan Martín-Pérez, Laia Pareras, Raquel Egea, Mohamed Alaraby, Jordi Manuel Cabrera-Gumbau, Iris Sarmiento, Jaime Martínez-Urtaza, Laura Rubio, Irene Barguilla, Ricard Marcos, Alba García-Rodríguez, Alba Hernández
Publié dans: Science of The Total Environment, Numéro 980, 2025, Page(s) 179545, ISSN 0048-9697
Éditeur: Elsevier BV
DOI: 10.1016/j.scitotenv.2025.179545

Investigating nanoplastics toxicity using advanced stem cell-based intestinal and lung in vitro models

Auteurs: Busch, Mathias; Brouwer, Hugo; Aalderink, Germaine; Bredeck, Gerrit; Kämpfer, Angela A.M.; Schins, Roel P.F.; Bouwmeester, Hans
Publié dans: Frontiers in Toxicology, Vol 5 (2023), Numéro 33, 2023, ISSN 2673-3080
Éditeur: Frontiers Media SA
DOI: 10.3389/ftox.2023.1112212

Emerging Role of NLRP3 Inflammasome and Pyroptosis in Liver Transplantation

Auteurs: Fernando Lucas-Ruiz, Alejandro Peñín-Franch, José Antonio Pons, Pablo Ramírez, Pablo Pelegrín, Santiago Cuevas, Alberto Baroja-Mazo
Publié dans: International Journal of Molecular Sciences, Numéro 23, 2024, Page(s) 14396, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms232214396

Emerging Role of NLRP3 Inflammasome and Pyroptosis in Liver Transplantation

Auteurs: Fernando Lucas-Ruiz; Alejandro Peñín-Franch; José Antonio Pons; Pablo Ramírez; Pablo Pelegrín; Santiago Cuevas; Alberto Baroja-Mazo
Publié dans: International Journal of Molecular Sciences, Vol 23, Iss 22, p 14396 (2022), 2022, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms232214396

Titanium-doped PET nanoplastics of environmental origin as a true-to-life model of nanoplastic

Auteurs: Aliro, Villacorta; Lourdes, Vela; Michelle, Morataya-Reyes; Raquel, Llorens-Chiralt; Laura, Rubio; Mohamed, Alaraby; Ricard, Marcos; Alba, Hernández
Publié dans: Science of The Total Environment, 2023, ISSN 0048-9697
Éditeur: Elsevier BV
DOI: 10.1016/j.scitotenv.2023.163151

Lipid-protein interactions regulating the canonical and the non-canonical NLRP3 inflammasome

Auteurs: Malvina, Pizzuto; Pablo, Pelegrin; Jean-Marie, Ruysschaert
Publié dans: Progress in Lipid Research, Numéro 37, 2022, ISSN 0163-7827
Éditeur: Pergamon Press Ltd.
DOI: 10.1016/j.plipres.2022.101182

Reproductive Toxicity of Nanomaterials Using Silver Nanoparticles and Drosophila as Models

Auteurs: Mohamed Alaraby, Doaa Abass, Javier Gutiérrez, Antonia Velázquez, Alba Hernández, Ricard Marcos
Publié dans: Molecules, Numéro 29, 2024, Page(s) 5802, ISSN 1420-3049
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules29235802

Pathogenic NLRP3 mutants form constitutively active inflammasomes resulting in immune-metabolic limitation of IL-1β production

Auteurs: Cristina Molina-López, Laura Hurtado-Navarro, Carlos J. García, Diego Angosto-Bazarra, Fernando Vallejo, Ana Tapia-Abellán, Joana R. Marques-Soares, Carmen Vargas, Segundo Bujan-Rivas, Francisco A. Tomás-Barberán, Juan I. Arostegui, & Pablo Pelegrin
Publié dans: Nature Communications, 2024, ISSN 2041-1723
Éditeur: Nature Publishing Group
DOI: 10.1038/s41467-024-44990-0

Pyroptosis and Redox Balance in Kidney Diseases

Auteurs: Santiago Cuevas, Pablo Pelegrín
Publié dans: Antioxidants & Redox Signaling, Numéro 35, 2021, Page(s) 40-60, ISSN 1523-0864
Éditeur: Mary Ann Liebert Inc.
DOI: 10.1089/ars.2020.8243

Hazard assessment of ingested polystyrene nanoplastics in <i>Drosophila</i> larvae

Auteurs: Mohamed Alaraby; Doaa Abass; Josefa Domenech; Alba Hernández; Ricard Marcos
Publié dans: Environmental Sciences: Nano, Numéro 1, 2022, ISSN 2051-8153
Éditeur: Royal Society of Chemistry
DOI: 10.1039/d1en01199e

Hazard assessment of different-sized polystyrene nanoplastics in hematopoietic human cell lines

Auteurs: Alireza Tavakolpournegari; Balasubramanyam Annangi; Aliro Villacorta; Gooya Banaei; Joan Martin; Susana Pastor; Ricard Marcos; Alba Hernández
Publié dans: Chemosphere, 2023, ISSN 0045-6535
Éditeur: Pergamon Press Ltd.
DOI: 10.1016/j.chemosphere.2023.138360

NLRP3 Inflammasome and Pyroptosis in Liver Pathophysiology: The Emerging Relevance of Nrf2 Inducers

Auteurs: Laura Hurtado-Navarro; Diego Angosto-Bazarra; Pablo Pelegrín; Alberto Baroja-Mazo; Santiago Cuevas
Publié dans: Antioxidants, Numéro 36, 2022, ISSN 2076-3921
Éditeur: MDPI Multidisciplinary Digital Publishing Institute
DOI: 10.3390/antiox11050870

Evolution of the gasdermin family and pyroptosis

Auteurs: Diego Angosto-Bazarra, Adriana Guijarro, Pablo Pelegrín
Publié dans: Developmental & Comparative Immunology, Numéro 149, 2024, Page(s) 105060, ISSN 0145-305X
Éditeur: Pergamon Press Ltd.
DOI: 10.1016/j.dci.2023.105060

The release of polylactic acid nanoplastics (PLA-NPLs) from commercial teabags. Obtention, characterization, and hazard effects of true-to-life PLA-NPLs

Auteurs: Gooya Banaei, Alba García-Rodríguez, Alireza Tavakolpournegari, Juan Martín-Pérez, Aliro Villacorta, Ricard Marcos, Alba Hernández
Publié dans: Journal of Hazardous Materials, Numéro Volume 458, 2023, 2023, Page(s) 131899, ISSN 0304-3894
Éditeur: Elsevier BV
DOI: 10.1016/j.jhazmat.2023.131899

Long-term exposure to nanoplastics alters molecular and functional traits related to the carcinogenic process

Auteurs: Barguilla, Irene; Domenech, Josefa; Ballesteros Ribera, Sandra; Rubio Lorente, Laura; Marcos Dauder, Ricardo; Hernández Bonilla, Alba
Publié dans: Journal of Hazardous Materials, Numéro 1, 2022, ISSN 0304-3894
Éditeur: Elsevier BV
DOI: 10.1016/j.jhazmat.2022.129470

Soluble P2X7 receptor is elevated in the plasma of COVID-19 patients and correlates with disease severity

Auteurs: Julio García-Villalba; Laura Hurtado-Navarro; Alejandro Peñín-Franch; Cristina Molina-López; Laura Martínez-Alarcón; Diego Angosto-Bazarra; Alberto Baroja-Mazo; Pablo Pelegrin; Pablo Pelegrin
Publié dans: Frontiers in Immunology, Numéro Vol. 13, 2022, ISSN 1664-3224
Éditeur: Frontiers Media S.A.
DOI: 10.1101/2022.03.04.483019

Long-Term Effects of Polystyrene Nanoplastics in Human Intestinal Caco-2 Cells.

Auteurs: Josefa Domenech; Mariana de Britto; Antonia Velázquez; Susana Pastor; Alba Hernández; Ricard Marcos; Constanza Cortés
Publié dans: Biomolecules, Numéro 1, 2021, ISSN 2218-273X
Éditeur: MDPI Multidisciplinary Digital Publishing Institute
DOI: 10.3390/biom11101442

Polylactic acid nanoplastics (PLA-NPLs) induce adverse effects on an in vitro model of the human lung epithelium: The Calu-3 air-liquid interface (ALI) barrier

Auteurs: Alba García-Rodríguez, Javier Gutiérrez, Aliro Villacorta, Jéssica Arribas Arranz, Iris Romero-Andrada, Alicia Lacoma, Ricard Marcos, Alba Hernández, Laura Rubio
Publié dans: Journal of Hazardous Materials, Numéro 475, 2024, Page(s) 134900, ISSN 0304-3894
Éditeur: Elsevier BV
DOI: 10.1016/j.jhazmat.2024.134900

Biobased, biodegradable but not bio-neutral: about the effects of polylactic acid nanoparticles on macrophages

Auteurs: Véronique Collin-Faure, Marianne Vitipon, Hélène Diemer, Sarah Cianférani, Elisabeth Darrouzet, Thierry Rabilloud
Publié dans: Environmental Science: Nano, Numéro 11, 2024, Page(s) 4102-4116, ISSN 2051-8153
Éditeur: Royal Society of Chemistry
DOI: 10.1039/d4en00335g

Toxicological Profiling and Long-Term Effects of Bare, PEGylated- and Galacto-Oligosaccharide-Functionalized Mesoporous Silica Nanoparticles

Auteurs: Irene Barguilla; Vicente Candela-Noguera; Patrick Oliver; Balasubramanyam Annangi; Paula Díez; Elena Aznar; Ramón Martínez-Máñez; Ricard Marcos; Alba Hernández; María Dolores Marcos
Publié dans: International Journal of Molecular Sciences, Vol 24, Iss 22, p 16158 (2023), Numéro 23, 2023, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms242216158

NLRP3 inflammasome activation and symptom burden in KRAS-mutated CMML patients is reverted by IL-1 blocking therapy

Auteurs: Laura Hurtado-Navarro, Ernesto José Cuenca-Zamora, Lurdes Zamora, Raúl Teruel-Montoya, Pablo Pelegrín, Francisca Ferrer-Marín
Publié dans: Cell Reports Medicine, Numéro Volume 4, ISSUE 12, 101329, December 19, 2023, 2023, ISSN 2666-3791
Éditeur: Elsevier
DOI: 10.1016/j.xcrm.2023.101329

Are bioplastics safe? Hazardous effects of polylactic acid (PLA) nanoplastics in Drosophila

Auteurs: Mohamed Alaraby, Doaa Abass, Marinella Farre, Alba Hernández, Ricard Marcos
Publié dans: Science of The Total Environment, Numéro Vol. 919, 2024, Page(s) 170592, ISSN 0048-9697
Éditeur: Elsevier BV
DOI: 10.1016/j.scitotenv.2024.170592

NLRP3 Inflammasome and Pyroptosis in Liver Pathophysiology: The Emerging Relevance of Nrf2 Inducers

Auteurs: Laura Hurtado-Navarro, Diego Angosto-Bazarra, Pablo Pelegrín, Alberto Baroja-Mazo, Santiago Cuevas
Publié dans: Antioxidants, Numéro 11, 2025, Page(s) 870, ISSN 2076-3921
Éditeur: MDPI AG
DOI: 10.3390/antiox11050870

Hazard Assessment of Polystyrene Nanoplastics in Primary Human Nasal Epithelial Cells, Focusing on the Autophagic Effects

Auteurs: Balasubramanyam Annangi; Aliro Villacorta; Montserrat López-Mesas; Victor Fuentes-Cebrian; Ricard Marcos; Alba Hernández
Publié dans: Biomolecules, 2023, ISSN 2218-273X
Éditeur: MDPI Multidisciplinary Digital Publishing Institute
DOI: 10.3390/biom13020220

P2X7 receptor activation impairs antitumour activity of natural killer cells

Auteurs: Alberto Baroja-Mazo, Alejandro Peñín-Franch, Fernando Lucas-Ruiz, Carlos de Torre-Minguela, Cristina Alarcón-Vila, Trinidad Hernández-Caselles, Pablo Pelegrín
Publié dans: British Journal of Pharmacology, 2022, ISSN 1476-5381
Éditeur: John Wiley & Sons Ltd on behalf of British Pharmacological Society
DOI: 10.1111/bph.15951

Harmful effects of true-to-life nanoplastics derived from PET water bottles in mouse alveolar macrophages

Auteurs: Alireza Tavakolpournegari, Aliro Villacorta, Michelle Morataya-Reyes, Jéssica Arribas Arranz, Gooya Banaei, Susana Pastor, Antonia Velázquez, Ricard Marcos, Alba Hernández, Balasubramanyam Annangi
Publié dans: Environmental Pollution, Numéro Vol. 348, 2024, ISSN 0269-7491
Éditeur: Pergamon Press Ltd.
DOI: 10.1016/j.envpol.2024.123823

New insights into the reproductive hazards posed by polystyrene nanoplastics

Auteurs: Mohamed Alaraby, Doaa Abass, Antonia Velázquez, Alba Hernández, Ricard Marcos
Publié dans: Journal of Hazardous Materials, Numéro 492, 2025, Page(s) 138210, ISSN 0304-3894
Éditeur: Elsevier BV
DOI: 10.1016/j.jhazmat.2025.138210

The in vitro gastrointestinal digestion-associated protein corona of polystyrene nano- and microplastics increases their uptake by human THP-1-derived macrophages

Auteurs: Brouwer, Hugo; Porbahaie, Mojtaba; Boeren, Sjef; Busch, Mathias; Bouwmeester, Hans
Publié dans: Particle and Fibre Toxicology, Numéro Vol 21, Iss 1, Pp 1-26 (2024), 2024, ISSN 1743-8977
Éditeur: BioMed Central
DOI: 10.21203/rs.3.rs-3453458/v1

Insights into the potential carcinogenicity of micro- and nano-plastics

Auteurs: Domenech, Josefe; Annangi, Balasubramanyam||; Marcos Dauder, Ricardo||; Hernández Bonilla, Alba||; Catalán Rodríguez, Julia||
Publié dans: Mutation Research/Reviews in Mutation Research, Numéro Volume 791, 2023, ISSN 1383-5742
Éditeur: Elsevier BV
DOI: 10.1016/j.mrrev.2023.108453

Physiological and pathophysiological functions of NLRP6: pro- and anti-inflammatory roles

Auteurs: Angosto-Bazarra, D., Molina-López, C. & Pelegrín, P.
Publié dans: Communications Biology, 2022, ISSN 2399-3642
Éditeur: Springer Nature
DOI: 10.1038/s42003-022-03491-w

In Vitro Approaches to Determine the Potential Carcinogenic Risk of Environmental Pollutants

Auteurs: Irene Barguilla, Veronique Maguer-Satta, Boris Guyot, Susana Pastor, Ricard Marcos, Alba Hernández
Publié dans: International Journal of Molecular Sciences, Numéro 24, 2025, Page(s) 7851, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms24097851

The long-term in vitro co-exposure of polyethylene terephthalate (PET) nanoplastics and cigarette smoke condensate exacerbates the induction of carcinogenic traits

Auteurs: Michelle Morataya-Reyes, Aliro Villacorta, Javier Gutiérrez-García, Raquel Egea, Joan Martín-Pérez, Irene Barguilla, Ricard Marcos, Alba Hernández
Publié dans: Journal of Hazardous Materials, Numéro 493, 2025, Page(s) 138359, ISSN 0304-3894
Éditeur: Elsevier BV
DOI: 10.1016/j.jhazmat.2025.138359

Polystyrene Nanoplastics as Carriers of Metals. Interactions of Polystyrene Nanoparticles with Silver Nanoparticles and Silver Nitrate, and Their Effects on Human Intestinal Caco-2 Cells

Auteurs: Josefa Domenech; Constanza Cortés; Lourdes Vela; Ricard Marcos; Alba Hernández
Publié dans: Biomolecules, Numéro 1, 2021, ISSN 2218-273X
Éditeur: MDPI
DOI: 10.3390/biom11060859

Can Current Regulations Account for Intentionally Produced Nanoplastics?

Auteurs: Fazel Abdolahpur Monikh, Steffen Foss Hansen, Martina G. Vijver, Esther Kentin, Maria Bille Nielsen, Anders Baun, Kristian Syberg, Iseult Lynch, Eugenia Valsami-Jones, and Willie J.G.M. Peijnenburg
Publié dans: Environmental Science & Technology, Numéro 0013936X, 2022, ISSN 0013-936X
Éditeur: American Chemical Society
DOI: 10.1021/acs.est.2c00965

ASC oligomer favors caspase-1CARD domain recruitment after intracellular potassium efflux

Auteurs: Fátima Martín-Sánchez; Vincent Compan; Alejandro Peñín-Franch; Ana Tapia-Abellán; Ana I. Gómez; María C. Baños-Gregori; Florian I. Schmidt; Pablo Pelegrin
Publié dans: Journal of Cell Biology, Numéro 222, 2023, ISSN 0021-9525
Éditeur: Rockefeller University Press
DOI: 10.1083/jcb.202003053

The potential effects of in vitro digestion on the physicochemical and biological characteristics of polystyrene nanoplastics

Auteurs: Lourdes Vela; Aliro Villacorta; Tom Venus; Irina Estrela-Lopis; Susana Pastor; Alba García-Rodriguez; Laura Rubio; Ricard Marcos; Alba Hernández
Publié dans: Environmental Pollution, Numéro 329, 2023, ISSN 0269-7491
Éditeur: Pergamon Press Ltd.
DOI: 10.1016/j.envpol.2023.121656

ASC nanobodies to counteract the consequences of inflammasome activation

Auteurs: Pablo Pelegrin; Sahil ADRIOUCH
Publié dans: EMBO Molecular Medicine, Numéro 17574684, 2022, ISSN 1757-4684
Éditeur: EMBO Press on behalf of the European Molecular Biology Organization
DOI: 10.15252/emmm.202216087

Effects of true-to-life PET nanoplastics using primary human nasal epithelial cells

Auteurs: Balasubramanyam Annangi; Aliro Villacorta; Lourdes Vela; Alireza Tavakolpournegari; Ricard Marcos; Alba Hernández
Publié dans: Environmental Toxicology and Pharmacology, Numéro 100, 2023, Page(s) 104140, ISSN 1382-6689
Éditeur: Elsevier BV
DOI: 10.1016/j.etap.2023.104140

Antagonistic in vivo interaction of polystyrene nanoplastics and silver compounds. A study using Drosophila

Auteurs: Mohamed Alaraby; Doaa Abass; Aliro Villacorta; Alba Hernández; Ricard Marcos
Publié dans: Science of The Total Environment, Numéro 1, 2022, ISSN 1879-1026
Éditeur: Elsevier
DOI: 10.1016/j.scitotenv.2022.156923

In vitro cell-transforming potential of secondary polyethylene terephthalate and polylactic acid nanoplastics

Auteurs: Josefa Domenech, Aliro Villacorta, Juan Francisco Ferrer, Raquel Llorens-Chiralt, Ricard Marcos, Alba Hernández, Julia Catalán
Publié dans: Journal of Hazardous Materials, Numéro 469, 2024, Page(s) 134030, ISSN 0304-3894
Éditeur: Elsevier BV
DOI: 10.1016/j.jhazmat.2024.134030

Kinetics and toxicity of nanoplastics in ex vivo exposed human whole blood as a model to understand their impact on human health

Auteurs: J. Arribas Arranz, A. Villacorta, L. Rubio, A. García-Rodríguez, G. Sánchez, M. Llorca, M. Farre, J.F. Ferrer, R. Marcos, A. Hernández
Publié dans: Science of The Total Environment, Numéro 948, 2025, Page(s) 174725, ISSN 0048-9697
Éditeur: Elsevier BV
DOI: 10.1016/j.scitotenv.2024.174725

Nanoplastics and arsenic co-exposures exacerbate oncogenic biomarkers under an in vitro long-term exposure scenario

Auteurs: Irene Barguilla; Josefa Domenech; Laura Rubio; Ricard Marcos; Alba Hernández
Publié dans: International Journal of Molecular Sciences; Volume 23; Numéro 6; Pages: 2958, Numéro 1, 2022, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.21203/rs.3.rs-1042926/v1

The internal dose makes the poison: higher internalization of polystyrene particles induce increased perturbation of macrophages

Auteurs: Collin-Faure, Véronique; Vitipon, Marianne; Torres, Anaëlle; Tanyeres, Ornella; Dalzon, Bastien; Rabilloud, Thierry
Publié dans: Frontiers in Immunology, 2023, ISSN 1664-3224
Éditeur: Frontiers Media SA
DOI: 10.3389/fimmu.2023.1092743

The hazardous impact of true-to-life PET nanoplastics in Drosophila

Auteurs: Mohamed Alaraby, Aliro Villacorta, Doaa Abass, Alba Hernández, Ricard Marcos
Publié dans: Science of The Total Environment, 2023, ISSN 0048-9697
Éditeur: Elsevier BV
DOI: 10.1016/j.scitotenv.2022.160954

Occurrence, analysis, and toxicity of polyethylene terephthalate microplastics: a review

Auteurs: Mohamed Alaraby, Doaa Abass, Antonia Velázquez, Alba Hernández, Ricard Marcos
Publié dans: Environmental Chemistry Letters, 2025, ISSN 1610-3653
Éditeur: Springer Verlag
DOI: 10.1007/s10311-025-01841-8

A new source of representative secondary PET nanoplastics. Obtention, characterization, and hazard evaluation

Auteurs: Aliro Villacorta, Laura Rubio, Mohamed Alaraby, Montserrat López-Mesas, Victor Fuentes-Cebrian, Oscar H. Moriones, Ricard Marcos, Alba Hernández*
Publié dans: Journal of Hazardous Materials, 2022, ISSN 0304-3894
Éditeur: Elsevier BV
DOI: 10.1016/j.jhazmat.2022.129593

Antagonistic in vivo interaction of polystyrene nanoplastics and silver compounds. A study using Drosophila

Auteurs: Mohamed Alaraby, Doaa Abass, Aliro Villacorta, Alba Hernández, Ricard Marcos
Publié dans: Science of The Total Environment, Numéro 842, 2025, Page(s) 156923, ISSN 0048-9697
Éditeur: Elsevier BV
DOI: 10.1016/j.scitotenv.2022.156923

Validated method for polystyrene nanoplastic separation in aqueous matrices by asymmetric-flow field flow fraction coupled to MALS and UV–Vis detectors

Auteurs: Iris H.Valido, Victor Fuentes-Cebrian, Alba Hernández, Manuel Valiente & Montserrat López-Mesas
Publié dans: Microchimica Acta, Numéro Volume 190, article number 285, 2023, ISSN 0026-3672
Éditeur: Springer Verlag
DOI: 10.1007/s00604-023-05851-7

NLRP3 and pyroptosis blockers for treating inflammatory diseases

Auteurs: Rebecca C.Coll, KateSchroder, PabloPelegrín
Publié dans: Trends in Pharmacological Sciences, Numéro 1, 2022, ISSN 0165-6147
Éditeur: Elsevier BV
DOI: 10.1016/j.tips.2022.04.003

Teabag-derived micro/nanoplastics (true-to-life MNPLs) as a surrogate for real-life exposure scenarios

Auteurs: Gooya Banaei, Doaa Abass, Alireza Tavakolpournegari, Joan Martín-Pérez, Javier Gutiérrez, Guyu Peng, Thorsten Reemtsma, Ricard Marcos, Alba Hernández, Alba García-Rodríguez
Publié dans: Chemosphere, Numéro 368, 2025, Page(s) 143736, ISSN 0045-6535
Éditeur: Pergamon Press Ltd.
DOI: 10.1016/j.chemosphere.2024.143736

"Fluorescent labeling of micro/nanoplastics for biological applications with a focus on “true-to-life"" tracking"

Auteurs: Aliro Villacorta, Camila Cazorla-Ares, Victor Fuentes-Cebrian, Iris H. Valido, Lourdes Vela, Fernando Carrillo-Navarrete, Michelle Morataya-Reyes, Karen Mejia-Carmona, Susana Pastor, Antonia Velázquez, Jéssica Arribas Arranz, Ricard Marcos, Montserrat López-Mesas, Alba Hernández
Publié dans: Journal of Hazardous Materials, Numéro 476, 2025, Page(s) 135134, ISSN 0304-3894
Éditeur: Elsevier BV
DOI: 10.1016/j.jhazmat.2024.135134

Extensive HPLC-tandem mass spectrometry characterization of soluble degradation products of biodegradable nanoplastics under environmentally relevant temperature and irradiation conditions

Auteurs: Thierry Douki, Vérane Bard, Maëva Boulée, Marie Carrière
Publié dans: Environmental Science: Nano, Numéro 11, 2024, Page(s) 3956-3965, ISSN 2051-8153
Éditeur: Royal Society of Chemistry
DOI: 10.1039/d3en00960b

About the effects of true-to-life polyethylene terephthalate nanoparticles on macrophages

Auteurs: Véronique Collin-Faure, Aliro Villacorta, Marianne Vitipon, Hélène Diemer, Sarah Cianférani, Ricard Marcos, Elisabeth Darrouzet, Alba Hernandez, Thierry Rabilloud
Publié dans: Environmental Science: Nano, Numéro 12, 2025, Page(s) 2799-2814, ISSN 2051-8153
Éditeur: Royal Society of Chemistry
DOI: 10.1039/d4en01063a

Hazard assessment of nanoplastics is driven by their surface-functionalization. Effects in human-derived primary endothelial cells

Auteurs: Joan Martín-Pérez, Aliro Villacorta, Gooya Banaei, Michelle Morataya-Reyes, Alireza Tavakolpournegari, Ricard Marcos, Alba Hernández, Alba García-Rodriguez
Publié dans: Science of The Total Environment, Numéro Volume 934, 2024, Page(s) 173236, ISSN 0048-9697
Éditeur: Elsevier BV
DOI: 10.1016/j.scitotenv.2024.173236

Titanium-doped PET nanoplastics, from opaque milk bottle degradation, as a model of environmental true-to-life nanoplastics. Hazardous effects on Drosophila

Auteurs: Mohamed Alaraby, Aliro Villacorta, Doaa Abass, Alba Hernández, Ricard Marcos
Publié dans: Environmental Pollution, Numéro Volume 341, 2024, Page(s) 122968, ISSN 0269-7491
Éditeur: Pergamon Press Ltd.
DOI: 10.1016/j.envpol.2023.122968

Size-dependent effects of PSNPLs on a human B-lymphocyte cell line

Auteurs: Tavakolpournegari A, B. Annangi, R. Marcos, A. Hernández
Publié dans: 2nd Conference on PLASTIC POLLUTION: the Textile Sector, an example towards a sustainable economy (PLASTIC'2022), Numéro Poster 16, 2022
Éditeur: IDAEA - CSIC

Polystyrene nanoplastics: surface- and size dependent effects on human primary endothelial cells

Auteurs: Martín J, A. García-Rodriguez, R. Marcos, A. Hernández
Publié dans: 2nd Conference on PLASTIC POLLUTION: the Textile Sector, an example towards a sustainable economy (PLASTIC'2022), Numéro Poster 17, 2022
Éditeur: IDAEA - CSIC

Ingested Nanoplastics Induced Histological, Genotoxic and Gene Expression Changes in Mouse Gastrointestinal Tract

Auteurs: Kuttykattil, Aswin; Loret, Thomas; Holme, Sonja; Rodríguez-Garraus, Adriana; Villacorta, Aliro; Catalán, Julia; Marcos, Ricard; Hernandez, Alba; Bussy, Cyrill
Publié dans: 2024
Éditeur: SETAC 2024 Seville Conference
DOI: 10.5281/zenodo.11208696

The potential effects of the in vitro digestion on the physicochemical and biological characteristics of polystyrene nanoplastics (Poster)

Auteurs: Vela L., A. Villacorta, T. Venus, S. Pastor, I. Estrela-Lopis, R. Marcos, A. Hernández
Publié dans: 2nd Conference on PLASTIC POLLUTION: the Textile Sector, an example towards a sustainable economy (PLASTIC'2022), Numéro Poster 20, 2022
Éditeur: IDAEA - CSIC

Development of a fluorescent staining protocol of nanoplastics for cell internalization studies

Auteurs: López-Mesas M., I.H. Valido, C. Cazorla Ares, V. Fuentes-Cebrian, A. Hernández, F Carrillo-Navarrete
Publié dans: 2nd Conference on PLASTIC POLLUTION: the Textile Sector, an example towards a sustainable economy (PLASTIC'2022), Numéro Poster 2, 2022
Éditeur: IDAEA - CSIC

Deciphering the effects induced by NPLs in peripheral blood immune cells

Auteurs: Arribas Arranz J, J. Ponomarenko, R. Marcos, A. Hernández
Publié dans: 2nd Conference on PLASTIC POLLUTION: the Textile Sector, an example towards a sustainable economy (PLASTIC'2022), Numéro Poster 15, 2022
Éditeur: IDAEA - CSIC

Hazard assessment of ingested polystyrene nanoplastics in Drosophila larvae (Poster)

Auteurs: Alaraby M, D. Abass, J. Domenech, A. Hernández, R. Marcos
Publié dans: 2nd Conference on PLASTIC POLLUTION: the Textile Sector, an example towards a sustainable economy (PLASTIC'2022), 2022
Éditeur: IDAEA-CSIC

Studying the effects of nano plastics derived from teabags in an in vitro model of the intestinal epithelium (Poster)

Auteurs: Banaei G, A. Villacorta, A. Tavakolpournegari, A. Garcia-Rodriguez, R. Marcos, A. Hernández
Publié dans: 2nd Conference on PLASTIC POLLUTION: the Textile Sector, an example towards a sustainable economy (PLASTIC'2022), Numéro Poster 21, 2022
Éditeur: IDAEA - CSIC

IMPACT of MICRO and NANO-PLASTICS on HUMAN HEALTH after INHALATION

Auteurs: Loret, Thomas; Issa, Rahaf; PLASTICHEAL consortium; Vranic, Sandra; Bussy, Cyrill
Publié dans: 2024
Éditeur: University of Manchester
DOI: 10.5281/zenodo.11213760

Dosimetry and Imaging of Micro and Nanoparticles by Means of High Resolution Techniques

Auteurs: T. Venus, T. Meyer, C. Zilberfain, J. Böttner, A. Lampen, O. Creutzenberg, M. Niehof, J. Meijer and I. Estrela-Lopis
Publié dans: Environmental Nanopollutants: Sources, Occurrence, Analysis and Fate, Numéro Special Collection: 2022 ebook collection Series: Chemistry in the Environment, 2022, Page(s) pp. 363-388., ISBN 978-1-83916-489-7
Éditeur: The Royal Society of Chemistry
DOI: 10.1039/9781839166570-00363

Potential human health effects following exposure to nano- and microplastics, lessons learned from nanomaterials

Auteurs: Hugo Brouwer, Femke L. N. van Oijen and Hans Bouwmeester
Publié dans: Present Knowledge in Food Safety A Risk-Based Approach Through The Food Chain, 2022, ISBN 978-0-12-823154-8
Éditeur: Academic Press (Elsevier)
DOI: 10.1016/b978-0-12-819470-6.00014-7

Sub-lethal in vitro effects of nanoplastics (PET and PS) in primary human nasal epithelial cells (HNEpC) –Role of the autophagy

Auteurs: B. Annangi J. Gutiérrez A. Villacorta R. Marcos A. Hernández
Publié dans: 2nd Conference on PLASTIC POLLUTION: the Textile Sector, an example towards a sustainable economy (PLASTIC'2022), 2022
Éditeur: IDAEA-CSIC

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