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Contenido archivado el 2024-06-17

Host-parasite relationship in susceptibility to tuberculosis

Objetivo

Vaccine candidates are emerging but the time and cost of TB clinical trials prohibits their evaluation. Surrogate markers are needed. Cells from carefully followed up contacts who do or do not develop disease are being studied forcytokine expression by RT-PCR in 3 African centres. VACSIS will add a 4th centre, upgrade technology to real time RT-PCR, and study markers of apoptosis that play a role in immune response regulation in TB. Meanwhile patients TB strains will by typed for polymorphisms in DNA repair genes, and this will be related to disease severity, transmission and immunology

Ámbito científico (EuroSciVoc)

Programa(s)

Tema(s)

Datos no disponibles

Convocatoria de propuestas

Datos no disponibles

Régimen de financiación

CSC - Cost-sharing contracts

Coordinador

UNIVERSITY COLLEGE LONDON
Aportación de la UE
Sin datos
Dirección
Cleveland Street 46
W1P 6DB LONDON
Reino Unido
Coste total
Sin datos

Participantes (5)