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Precision micromechanical lever for next-generation cell culture systems

Objective

Instruments to culture cells under confinement conditions are not yet available in the market, yet there is a clear need to culture cells in conditions that most closely mimic in vivo conditions. In particular, such a tool would allow the study of cells in a mechanical environment that resembles the high pressure inside tumours. Based on studies of the market and our designs, we estimate a yearly market of 25 million euros from academic cancer research labs alone. We will further expand these tools for applications in white blood cell maturation and stem cell differentiation.
For this project, we need to hire a researcher capable of designing a high-precision instrument to exert confinement on the cells uniformly without crushing them. The basic design has already been validated, but the current method to exert pressure is unreliable and cannot be commercialized. We do not have the precision instrumentation knowledge in-house to build a better tool and we have been unable to find a suitable candidate in the local market.
We propose to find an associate who is enthusiastic about entrepreneurship, has expertise in precision instrumentation and experience in microfluidics and cell culture. We will train this candidate in entrepreneurship from the perspective of a start-up company and encourage them to start their own spin-off company with the instruments they build. At Elvesys, we have already created two successful spin-off companies.
With these tools, Elvesys will gain an opening in the market of next-generation cell culture tools. We can then establish ourselves as the preferred partners of academic researchers in providing microfluidic solutions to cell culture problems. We will also position ourselves in a pioneering position to become a key player in a strategic sector. Our long-term strategic goal is to develop tools for medical diagnostics, personalized medicine and organ-on-a-chip technologies.

Fields of science (EuroSciVoc)

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Programme(s)

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Topic(s)

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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

CSA - Coordination and support action

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) H2020-INNOSUP-2016-2017

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Coordinator

ELVESYS
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 88 750,00
Address
172 RUE DE CHARONNE B2 2 EME ETAGE
75011 PARIS
France

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Ile-de-France Ile-de-France Paris
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Links
Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 88 750,00
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