Predicting the Impact of Monoclonal Antibodies & Vaccines on Antimicrobial Resistance

Projektinformationen

PrIMAVeRa

ID Finanzhilfevereinbarung: 101034420

DOI

10.3030/101034420

EK-Unterschriftsdatum 9 November 2021

Startdatum 1 November 2021

Enddatum 31 Oktober 2026

Finanziert unter

• SOCIETAL CHALLENGES - Health, demographic change and well-being

Gesamtkosten

€ 9 250 000,00

EU-Beitrag

€ 6 500 000,00

Koordiniert durch

EUROPEAN VACCINE INITIATIVE E.V
Germany

CORDIS bietet Links zu öffentlichen Ergebnissen und Veröffentlichungen von HORIZONT-Projekten.

Links zu Ergebnissen und Veröffentlichungen von RP7-Projekten sowie Links zu einigen Typen spezifischer Ergebnisse wie Datensätzen und Software werden dynamisch von OpenAIRE abgerufen.

Leistungen

Documents, reports (10)

Systematic review on economic outcomes associated with AMR
Population-based models for selected cases studies and findings on gaps in data and methods identified
Communication policy and plan for dissemination and exploitation
Registered statistical analysis plan
Systematic review and inventory of existing population-based AMR models

Systematic review and inventory of existing populationbased AMR models

Systematic review on frequency measures of burden of AMR
Systematic review on health outcomes associated with AMR
Viewpoint on conceptual and technical challenges in determining burden of AMR
Databases selected after systematic review
Kick-off meeting

Kickoff meeting

Open Research Data Pilot (1)

Updated Data repository feeding into the EPI-Net structure (https://epi-net.eu)

Updated Data repository feeding into the EPINet structure httpsepineteu

Websites, patent fillings, videos etc. (1)

Project website

Veröffentlichungen

Peer reviewed articles (13)

Targeted mupirocin-based decolonization for Staphylococcus aureus carriers and the subsequent risk of mupirocin resistance in haemodialysis patients – a longitudinal study over 20 years

Autoren: N. Hassoun-Kheir, N. Buetti, V. Olivier, M. Perez, J. Frossard, G. Renzi, J. Schrenzel, P. Saudan, S Harbarth
Veröffentlicht in: The Journal of Hospital Infection, Ausgabe Volume 135, May 2023, 2023, Seite(n) 55-58, ISSN 1532-2939
Herausgeber: Elsevier
DOI: 10.1016/j.jhin.2023.01.019

Using contact network dynamics to implement efficient interventions against pathogen spread in hospital settings: A modelling study

Autoren: Leclerc QJ, Duval A, Guillemot D, Opatowski L, Temime L
Veröffentlicht in: PLOS Medicine, Ausgabe 21(7): e1004433, 2024, ISSN 1549-1277
Herausgeber: Public Library of Science
DOI: 10.1371/journal.pmed.1004433

How to: share and reuse data - challenges and solutions from PrIMAVeRa project

Autoren: Mariana Guedes, Almudena de la Serna Bazan, Elena Rubio-Martn, Lydia Barrera Pulido, Virginia Palomo, Alen Pilji, Quentin J. Leclerc, Emmanuel Aris, Venanzio Vella, Asta Dambrauskien, Julie V. Robotham, Astrid Prez, Nasreen Hassoun-Kheir, Marlieke E.A. de Kraker, Fabiana Arieti, Ruth Joanna Davis, Evelina Tacconelli, Elena Salamanca-Rivera, Jess Rodrguez-Bao
Veröffentlicht in: Clinical Microbiology and Infection, 2025, ISSN 1198-743X
Herausgeber: Blackwell Publishing Inc.
DOI: 10.1016/j.cmi.2025.01.024

A systematic review on the excess health risk of antibiotic-resistant bloodstream infections for six key pathogens in Europe

Autoren: Nasreen Hassoun-Kheir, Mariana Guedes, Marie-Therese Ngo Nsoga, Lorenzo Argante, Fabiana Arieti, Beryl P. Gladstone, Rhys Kingston, Nichola R. Naylor, Maria D. Pezzani, Koen B. Pouwels, Julie V. Robotham, Jesús Rodríguez-Baño, Evelina Tacconelli, Venanzio Vella, Stephan Harbarth, Marlieke E.A. de Kraker, Benedetta Barana, Eva Cappelli, Maria Elena De Rui, Radwa A. El-Abasiri, Liliana Galia, Jer
Veröffentlicht in: Clinical Microbiology and Infection, Ausgabe 30, 2024, Seite(n) S14-S25, ISSN 1198-743X
Herausgeber: Blackwell Publishing Inc.
DOI: 10.1016/j.cmi.2023.09.001

Excess resource use and cost of drug-resistant infections for six key pathogens in Europe: a systematic review and Bayesian meta-analysis

Autoren: Rhys Kingston, Venanzio Vella, Koen B. Pouwels, Johannes E. Schmidt, Radwa A. Abdelatif El-Abasiri, Eduardo Reyna-Villasmil, Nasreen Hassoun-Kheir, Stephan Harbarth, Jesús Rodríguez-Baño, Evelina Tacconelli, Fabiana Arieti, Beryl Primrose Gladstone, Marlieke E.A. de Kraker, Nichola R. Naylor, Julie V. Robotham, Lorenzo Argante, Benedetta Barana, Eva Cappelli, Maria Elena De Rui, Liliana Galia,
Veröffentlicht in: Clinical Microbiology and Infection, Ausgabe Volume 30, Supplement 1, 2024, 2024, Seite(n) S26-S36, ISSN 1198-743X
Herausgeber: Blackwell Publishing Inc.
DOI: 10.1016/j.cmi.2023.12.013.

Expert consensus on antimicrobial resistance research priorities to focus development and implementation of antibacterial vaccines and monoclonal antibodies

Autoren: Nasreen Hassoun-Kheir, Mariana Guedes, Fabiana Arieti, Maria Diletta Pezzani, Beryl Primrose Gladstone, Julie V Robotham, Koen B Pouwels, Rhys Kingston, Yehuda Carmeli, Alessandro Cassini, Michele Cecchini, Francis Drobniewski, Isabel Frost, Jeroen Geurtsen, Andreas Kronenberg, Mila Nu Nu Htay, Mical Paul, Nuno Rocha-Pereira, Jesús Rodríguez-Baño, Luigia Scudeller, Andrew J Stewardson, Evelina
Veröffentlicht in: Eurosurveillance, Ausgabe 29, 2024, ISSN 1560-7917
Herausgeber: ECDC
DOI: 10.2807/1560-7917.es.2024.29.47.2400212

Contextual Hospital Conditions and the Risk of Nosocomial SARS-CoV-2 Infection: A Matched Case-Control Study with Density Sampling in a Large Portuguese Hospital

Autoren: Francisco Almeida, Sofia Correia, Cátia Leal, Mariana Guedes, Raquel Duro, Paulo Andrade, Afonso Pedrosa, Nuno Rocha-Pereira, Carlos Lima-Alves, Ana Azevedo
Veröffentlicht in: Journal of Clinical Medicine, Ausgabe 13, 2025, Seite(n) 5251, ISSN 2077-0383
Herausgeber: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm13175251

Timing of Cefuroxime Surgical Antimicrobial Prophylaxis and Its Association With Surgical Site Infections

Autoren: Rami Sommerstein, Nicolas Troillet, Stephan Harbarth, Marlieke E.A. de Kraker, Danielle Vuichard-Gysin, Stefan P. Kuster, Andreas F. Widmer, null null, Carlo Balmelli, Delphine Berthod, Niccolo Buetti
Veröffentlicht in: JAMA Network Open, Ausgabe 6, 2023, Seite(n) e2317370, ISSN 2574-3805
Herausgeber: American Medical Association (AMA)
DOI: 10.1001/jamanetworkopen.2023.17370

Understanding the impact of antimicrobial resistance on outcomes of bloodstream infections in low- and middle-income countries

Autoren: Marlieke E. A. de Kraker
Veröffentlicht in: PLOS Medicine, Ausgabe 20, 2023, Seite(n) e1004262, ISSN 1549-1676
Herausgeber: Public Library of Science (PLoS)
DOI: 10.1371/journal.pmed.1004262

Epidemiology of Citrobacter spp. infections among hospitalized patients: a systematic review and meta-analysis

Autoren: Pérince Fonton, Nasreen Hassoun-Kheir, Stephan Harbarth
Veröffentlicht in: BMC Infectious Diseases, Ausgabe 24, 2024, ISSN 1471-2334
Herausgeber: BioMed Central
DOI: 10.1186/s12879-024-09575-8

The neglected model validation of antimicrobial resistance transmission models – a systematic review

Autoren: Maja L. Brinch, Andrea Palladino, Jeroen Geurtsen, Thierry Van Effelterre, Lorenzo Argante, Michael J. McConnell, Lene Christiansen, Michelle A. Pihl, Natasja K. Lund, Tine Hald
Veröffentlicht in: Antimicrobial Resistance & Infection Control, Ausgabe 14, 2025, ISSN 2047-2994
Herausgeber: Springer Science and Business Media LLC
DOI: 10.1186/s13756-025-01574-x

Frequency of bloodstream infections caused by six key antibiotic-resistant pathogens for prioritization of research and discovery of new therapies in Europe: a systematic review

Autoren: Maria Diletta Pezzani, Fabiana Arieti, Nithya Babu Rajendran, Benedetta Barana, Eva Cappelli, Maria Elena De Rui, Liliana Galia, Nasreen Hassoun-Kheir, Lorenzo Argante, Johannes Schmidt, Jesus Rodriguez-Bano, Stephan Harbarth, Marlieke de Kraker, Beryl Primrose Gladstone, Evelina Tacconelli
Veröffentlicht in: Clinical Microbiology and Infection, Ausgabe Volume 30, Supplement 1, 2024, 2024, Seite(n) S4-S13, ISSN 1198-743X
Herausgeber: Blackwell Publishing Inc.
DOI: 10.1016/j.cmi.2023.10.019.

Synthesizing pathogen- and infection-specific estimates of the burden of antimicrobial resistance in Europe for health-technology assessment: gaps, heterogeneity, and bias

Autoren: Julie V. Robotham, Evelina Tacconelli, Venanzio Vella, Marlieke E.A. de Kraker
Veröffentlicht in: Clinical Microbiology and Infection, Ausgabe Volume 30, Supplement 1, 2024, 2024, Seite(n) S1-S3, ISSN 1198-743X
Herausgeber: Blackwell Publishing Inc.
DOI: 10.1016/j.cmi.2023.10.004

Other (2)

Global burden of antimicrobial resistance: essential pieces of a global puzzle

Autoren: Marlieke E A de Kraker, Stephan Harbarth
Veröffentlicht in: The Lancet, Ausgabe Volume 399, Ausgabe 10344, P2347, June 25, 2022, 2022
Herausgeber: Elsevier
DOI: 10.1016/s0140-6736(22)00940-0

Estimating antimicrobial resistance burden in Europe—what are the next steps?

Autoren: Nasreen Hassoun-Kheir, Stephan Harbarth
Veröffentlicht in: The Lancet Public Health, Ausgabe Volume 7, Ausgabe 11, E886-E887, November 01, 2022, 2022
Herausgeber: Elsevier
DOI: 10.1016/s2468-2667(22)00250-x