NEXT GENERATION TOOLS FOR GENOME-CENTRIC MULTIMODAL DATA INTEGRATION IN PERSONALISED CARDIOVASCULAR MEDICINE

Informazioni relative al progetto

NextGen

ID dell’accordo di sovvenzione: 101136962

DOI

10.3030/101136962

Data della firma CE 1 Dicembre 2023

Data di avvio 1 Gennaio 2024

Data di completamento 31 Dicembre 2027

Finanziato da

• Health

Costo totale

€ 7 601 771,25

Contributo UE

€ 7 601 770,00

Coordinato da

UNIVERSITAIR MEDISCH CENTRUM UTRECHT
Netherlands

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Documents, reports (7)

Stakeholder engagement plan
Ethical considerations on human in the loop AI

Report on ethical considerations on human in the loop AI based on existing literature

Pathfinder frameworks and pathways

Report on planned frameworks and pathways for Pathfinder

Technical methods for federated genomic analysis

Report on the selected methods for federated genomic analysis

Platform design and architecture blueprint
Dissemination and Communication Plan
Project website

Demonstrators, pilots, prototypes (3)

Implementation of federated genomic analysis methods-1

Initial prototype of federated genomic analysis

Data discovery functionality demonstrated-1

Initial prototype of the data discovery functionality

Accelerated secondary genomic analysis software -1

Accelerated secondary genomic analysis software (initial prototype)

Data Management Plan (1)

Data Management Plan & Data Integration Framework

Data sets, microdata, etc (1)

Synthetic datasets for testing and piloting-1

Initial synthetic dataset

Pubblicazioni

Peer reviewed articles (3)

Parkinson's disease age at onset genome‐wide association study: Defining heritability, genetic loci, and α‐synuclein mechanisms

Autori: Cornelis Blauwendraat, Karl Heilbron, Costanza L. Vallerga, Sara Bandres‐Ciga, Rainer von Coelln, Lasse Pihlstrøm, Javier Simón‐Sánchez, Claudia Schulte, Manu Sharma, Lynne Krohn, Ari Siitonen, Hirotaka Iwaki, Hampton Leonard, Alastair J. Noyce, Manuela Tan, J. Raphael Gibbs, Dena G. Hernandez, Sonja W. Scholz, Joseph Jankovic, Lisa M. Shulman, Suzanne Lesage, Jean‐Christophe Corvol, Alexis Brice, Jacobus J. van Hilten, Johan Marinus, null null, Johanna Eerola‐Rautio, Pentti Tienari, Kari Majamaa, Mathias Toft, Donald G. Grosset, Thomas Gasser, Peter Heutink, Joshua M. Shulman, Nicolas Wood, John Hardy, Huw R. Morris, David A. Hinds, Jacob Gratten, Peter M. Visscher, Ziv Gan‐Or, Mike A. Nalls, Andrew B. Singleton, null null
Pubblicato in: Movement Disorders, Numero 34, 2023, ISSN 0885-3185
Editore: Wiley
DOI: 10.1002/MDS.27659

The Effects of FABP4 on Cardiovascular Disease in the Aging Population

Autori: Ellen M. van der Ark-Vonk, Mike V. Puijk, Gerard Pasterkamp, Sander W. van der Laan
Pubblicato in: Current Atherosclerosis Reports, Numero 26, 2024, ISSN 1523-3804
Editore: Springer Science and Business Media LLC
DOI: 10.1007/S11883-024-01196-5

Decentralised Semantics: A Semantic Engine User Perspective

Autori: Carly M. Huitema, Paul Knowles, Philippe Page, A. Michelle Edwards
Pubblicato in: Data Science Journal, Numero 23, 2024, ISSN 1683-1470
Editore: Ubiquity Press, Ltd.
DOI: 10.5334/DSJ-2024-042