NEXT GENERATION TOOLS FOR GENOME-CENTRIC MULTIMODAL DATA INTEGRATION IN PERSONALISED CARDIOVASCULAR MEDICINE

Informazioni relative al progetto

NextGen

ID dell’accordo di sovvenzione: 101136962

DOI

10.3030/101136962

Data della firma CE 1 Dicembre 2023

Data di avvio 1 Gennaio 2024

Data di completamento 31 Dicembre 2027

Finanziato da

• Health

Costo totale

€ 7 601 771,25

Contributo UE

€ 7 601 770,00

Coordinato da

UNIVERSITAIR MEDISCH CENTRUM UTRECHT
Netherlands

Periodic Reporting for period 1 - NextGen (NEXT GENERATION TOOLS FOR GENOME-CENTRIC MULTIMODAL DATA INTEGRATION IN PERSONALISED CARDIOVASCULAR MEDICINE)

Periodo di rendicontazione: 2024-01-01 al 2025-06-30

Sintesi del contesto e degli obiettivi generali del progetto

The overall objective of NextGen is to build novel and synergistic tools to enable portable multimodal, multiomic and clinically-oriented research in high-impact areas of cardiovascular medicine. NextGen tools will benefit researchers, innovators and healthcare professionals by identifying and overcoming health data linkage barriers in exemplar use cases which are complex or intractable with existing technology. Consequently, it will benefit patients, providing faster diagnosis, and better treatments (including personalised medicine). A comprehensive gap analysis of the existing landscape, factoring in ongoing initiatives will ensure NextGen deliverables are forward-looking and complementary. In particular, the NextGen embedded governance framework and robust regulatory processes will ensure secure multi-jurisdictional phenotype and genomic data access aligned with initiatives including “1+ Million Genomes” and European Health Data Space.

Lavoro eseguito dall’inizio del progetto fino alla fine del periodo coperto dalla relazione e principali risultati finora ottenuti

The project remains on track. Significant progress has been made in decentralized data management, architecture design, federated analytics, multimodal integration, governance, and stakeholder engagement. Pathfinder and MVP services have been deployed, laying the foundation for cross-jurisdictional interoperability, privacy-preserving data sharing, and sustainable exploitation of project results.

Progressi oltre lo stato dell’arte e potenziale impatto previsto (incluso l’impatto socioeconomico e le implicazioni sociali più ampie del progetto fino ad ora)

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