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Enhanced RESolution Quantum sensing for metabolic brain imaging

Objective

Quantum sensing is starting to become a reality in a number of industries, yet its potential in medicine remains largely unrealised. Clinical use demands exceptional precision and robustness, which current technologies cannot provide. Hyperpolarised MRI (HP-MRI) could change this by enabling quantum-enhanced metabolic imaging, e. g. for the reliable detection of small brain metastases. Brain metastases occur in 10-20% of cancer patients with fewer than 5% living beyond three years after diagnosis. Earlier detection could shift patients into more effective treatment pathways and significantly improve outcomes, yet small lesions often remain invisible with today’s imaging. RESQ will overcome this barrier by developing resolution-enhanced HP-MRI as an application-specific quantum sensing to meet the demands of brain imaging.
RESQ unites complementary strengths and establishes a long-lasting partnership between NVision Imaging Technologies, a German SME leading innovation in hyperpolarisation; Yonsei öUniversity, the Republic of Korea's leading research centre in HP-MRI; Ulm University with deep expertise in advanced quantum control and Tesla Dynamic Coils (Netherlands), an industry leader in MR coils. Together, we will (i) optimise parahydrogen generation and storage for reproducible high spin order; (ii) design quantum-optimised acquisition and reconstruction, integrating tailored RF pulses, compressed sensing, and machine learning and (iii) build dedicated dual-tuned brain coils. We will create the first EU-ROK quantum imaging node supporting researcher exchanges, joint training, sustainable infrastructure and contributions to international HP-MRI standards. By bridging today’s resolution-limited HP-MRI to disease-focused quantum sensing, RESQ strengthens the European quantum ecosystem, anchors long-term EU-ROK collaboration and lays the foundation for clinical translation.

Fields of science (EuroSciVoc)

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Keywords

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Programme(s)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

HORIZON-RIA - HORIZON Research and Innovation Actions

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) HORIZON-CL4-2025-03

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Coordinator

NVISION QUANTUM TECHNOLOGIES GMBH
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 850 000,00
Address
WOLFGANG-PAUL-STRASSE 2
89081 ULM
Germany

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Baden-Württemberg Tübingen Ulm, Stadtkreis
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 850 000,00

Participants (4)

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