PERtussIS COrrelates of Protection Europe - Sofia ref.: 115910

Project Information

PERISCOPE

Grant agreement ID: 115910

DOI

10.3030/115910

Project closed

EC signature date 1 August 2016

Start date 1 March 2016

End date 31 August 2022

Funded under

• SOCIETAL CHALLENGES - Health, demographic change and well-being

Total cost

€ 29 926 687,00

EU contribution

€ 21 000 000,00

Coordinated by

STICHTING RADBOUD UNIVERSITAIR MEDISCH CENTRUM
Netherlands

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Documents, reports (5)

Report on newsletters (1 per semester) sent to relevant consortia

Migration

Summary report on first plenary conference with key stakeholders

Migration

Report on interactions with key stakeholders

Migration

Summary report on E-bulletins e-mailed once a year to all key stakeholders

Migration

PERISCOPE position paper

Migration

Other (1)

Dissemination toolkit

Migration

Websites, patent fillings, videos etc. (1)

External Project website

Migration

Publications

Peer reviewed articles (23)

Development and Standardization of a High-Throughput Bordetella pertussis Growth-Inhibition Assay

Author(s): Anaïs Thiriard, Dominique Raze, Camille Locht
Published in: Frontiers in Microbiology, Issue 11, 2020, Page(s) Art177, ISSN 1664-302X
Publisher: Frontiers Media
DOI: 10.3389/fmicb.2020.00777

IL-17 mediates protective immunity against nasal infection with Bordetella pertussis by mobilizing neutrophils, especially Siglec-F+ neutrophils

Author(s): Lisa Borkner, Lucy M. Curham, Mieszko M. Wilk, Barry Moran, Kingston H. G. Mills
Published in: Mucosal Immunology, Issue 14/5, 2021, ISSN 1933-0219
Publisher: Nature Publishing Group
DOI: 10.1038/s41385-021-00407-5

Memory B Cell Activation Induced by Pertussis Booster Vaccination in Four Age Groups of Three Countries

Author(s): Pauline Versteegen, Alex-Mikael Barkoff, Marta Valente Pinto, Jan van de Kasteele, Aapo Knuutila 2 , Sagida Bibi, Lia de Rond, Johanna Teräsjärvi, Katherine Sanders, Mary-Lène de Zeeuw-Brouwer, Raakel Luoto, Hinke Ten Hulscher, Elizabeth A Clutterbuck, Elisabeth A M Sanders, Jussi Mertsola, Guy A M Berbers, Qiushui He, Dominic F Kelly, Anne-Marie Buisman; PERISCOPE Consortium
Published in: Frontiers in Immunology, Issue 13, 2022, ISSN 1664-3224
Publisher: Frontiers Media S.A.
DOI: 10.3389/fimmu.2022.864674

A qPCR assay for Bordetella pertussis cells that enumerates both live and dead bacteria

Author(s): Stacy Ramkissoon, Iain MacArthur, Muktar Ibrahim, Hans de Graaf, Robert C. Read, Andrew Preston
Published in: PLOS ONE, Issue 15/4, 2020, Page(s) e0232334, ISSN 1932-6203
Publisher: Public Library of Science
DOI: 10.1371/journal.pone.0232334

Uncovering Distinct Primary Vaccination-Dependent Profiles in Human Bordetella pertussis Specific CD4+ T-Cell Responses Using a Novel Whole Blood Assay

Author(s): Eleonora E. Lambert, Véronique Corbière, Jacqueline A. M. van Gaans-van den Brink, Maxime Duijst, Prashanna Balaji Venkatasubramanian, Elles Simonetti, Martijn Huynen, Dimitri D. Diavatopoulos, Pauline Versteegen, Guy A. M. Berbers, Françoise Mascart, Cécile A. C. M. van Els
Published in: Vaccines, Issue 8/2, 2020, Page(s) 225, ISSN 2076-393X
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/vaccines8020225

Highly Sensitive Flow Cytometry Allows Monitoring of Changes in Circulating Immune Cells in Blood After Tdap Booster Vaccination

Author(s): Annieck M Diks, Indu Khatri, Liesbeth E M Oosten, Bas de Mooij, Rick J Groenland, Cristina Teodosio, Martin Perez-Andres, Alberto Orfao, Guy A M Berbers, Jaap Jan Zwaginga, Jacques J M van Dongen, Magdalena A Berkowska
Published in: Frontiers in Immunology, 2021, ISSN 1664-3224
Publisher: Frontiers Media S.A.
DOI: 10.3389/fimmu.2021.666953

Age Distribution of Multiple Functionally Relevant Subsets of CD4+ T Cells in Human Blood Using a Standardized and Validated 14-Color EuroFlow Immune Monitoring Tube

Author(s): Vitor Botafogo, Martín Pérez-Andres, María Jara-Acevedo, Paloma Bárcena, Georgiana Grigore, Alejandro Hernández-Delgado, Daniela Damasceno, Suzanne Comans, Elena Blanco, Alfonso Romero, Sonia Arriba-Méndez, Irene Gastaca-Abasolo, Carlos Eduardo Pedreira, Jacqueline A. M. van Gaans-van den Brink, Véronique Corbiere, Françoise Mascart, Cécile A. C. M. van Els, Alex-Mikael Barkoff, Andrea Ma
Published in: Frontiers in Immunology, Issue 11, 2020, Page(s) Art166, ISSN 1664-3224
Publisher: Frontiers Immunology
DOI: 10.3389/fimmu.2020.00166

Maternal acellular pertussis vaccination in mice impairs cellular immunity to Bordetella pertussis infection in offspring

Author(s): Violaine Dubois, Jonathan Chatagnon, Manon Depessemier, and Camille Locht
Published in: JCI Insight, 2023, ISSN 2379-3708
Publisher: JCI Insight
DOI: 10.1172/jci.insight.167210

Development of a standardized and validated flow cytometry approach for monitoring of innate myeloid immune cells in human blood

Author(s): Kyra van der Pan, Sandra de Bruin-Versteeg, Daniela Damasceno, Alejandro Hernández-Delgado, Alita J. van der Sluijs-Gelling, Wouter B. L. van den Bossche, Inge F. de Laat, Paula Díez, Brigitta A. E. Naber, Annieck M. Diks, Magdalena A. Berkowska, Bas de Mooij, Rick J. Groenland, Fenna J. de Bie, Indu Khatri, Sara Kassem, Anniek L. de Jager, Alesha Louis, Julia Almeida, Jacqueline A. M. van Gaans
Published in: Frontiers in Immunology, Issue 13, 2022, ISSN 1664-3224
Publisher: Frontiers Media S.A.
DOI: 10.3389/fimmu.2022.935879

Differences in epitope‐specific antibodies to pertussis toxin after infection and acellular vaccinations

Author(s): Aapo Knuutila, Tine Dalby, Alex‐Mikael Barkoff, Charlotte Sværke Jørgensen, Kurt Fuursted, Jussi Mertsola, Kevin Markey, Qiushui He
Published in: Clinical & Translational Immunology, Issue 9/8, 2020, ISSN 2050-0068
Publisher: John Wiley & Sons Australia, Ltd
DOI: 10.1002/cti2.1161

Investigating Bordetella pertussis colonisation and immunity: protocol for an inpatient controlled human infection model

Author(s): Hans de Graaf, Diane Gbesemete, Andrew R. Gorringe, Dimitri A. Diavatopoulos, Kent E. Kester, Saul N. Faust, Robert C. Read
Published in: BMJ Open, Issue 7/10, 2017, Page(s) e018594, ISSN 2044-6055
Publisher: BMJ Publishing Group
DOI: 10.1136/bmjopen-2017-018594

In vivo imaging of bacterial colonization of the lower respiratory tract in a baboon model of Bordetella pertussis infection and transmission

Author(s): Thibaut Naninck, Loïc Coutte, Céline Mayet, Vanessa Contreras, Camille Locht, Roger Le Grand, Catherine Chapon
Published in: Scientific Reports, Issue 8/1, 2018, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-018-30896-7

Azithromycin Clears Bordetella pertussis Infection in Mice but Also Modulates Innate and Adaptive Immune Responses and T Cell Memory

Author(s): Lisa Borkner, Alicja Misiak, Mieszko M. Wilk, Kingston H. G. Mills
Published in: Frontiers in Immunology, Issue 9, 2018, ISSN 1664-3224
Publisher: Frontiers in Immunology
DOI: 10.3389/fimmu.2018.01764

PERISCOPE: road towards effective control of pertussis

Author(s): Dimitri A. Diavatopoulos, Kingston H.G. Mills, Kent E. Kester, Beate Kampmann, Marcela Silerova, Ulrich Heininger, Jacques J.M. van Dongen, Robbert G. van der Most, Martijn A. Huijnen, Emilio Siena, Nathalie Mielcarek, Martina M. Ochs, Philippe Denoël, Guy Berbers, Annemarie M. Buisman, Marien I. de Jonge, Craig Fenwick, Andrew Gorringe, Qiushui He, Dominic Kelly, Roger Le Grand, Camille Locht, F
Published in: The Lancet Infectious Diseases, 2018, ISSN 1473-3099
Publisher: The Lancet Publishing Group
DOI: 10.1016/s1473-3099(18)30646-7

Controlled Human Infection With Bordetella pertussis Induces Asymptomatic, Immunizing Colonization

Author(s): Hans de Graaf, Muktar Ibrahim, Alison R Hill, Diane Gbesemete, Andrew T Vaughan, Andrew Gorringe, Andrew Preston, Annemarie M Buisman, Saul N Faust, Kent E Kester, Guy A M Berbers, Dimitri A Diavatopoulos, Robert C Read
Published in: Clinical Infectious Diseases, 2019, ISSN 1058-4838
Publisher: University of Chicago Press
DOI: 10.1093/cid/ciz840

Immunization with whole cell but not acellular pertussis vaccines primes CD4 T RM cells that sustain protective immunity against nasal colonization with Bordetella pertussis

Author(s): Mieszko M. Wilk, Lisa Borkner, Alicja Misiak, Lucy Curham, Aideen C. Allen, Kingston H. G. Mills
Published in: Emerging Microbes & Infections, Issue 8/1, 2019, Page(s) 169-185, ISSN 2222-1751
Publisher: Nature Publishing Group
DOI: 10.1080/22221751.2018.1564630

Suppression of mucosal Th17 memory responses by acellular pertussis vaccines enhances nasal Bordetella pertussis carriage

Author(s): Violaine Dubois, Jonathan Chatagnon, Anaïs Thiriard, Hélène Bauderlique-Le Roy, Anne-Sophie Debrie, Loïc Coutte, Camille Locht
Published in: npj Vaccines, Issue 6/1, 2021, Page(s) Art 6, ISSN 2059-0105
Publisher: Nature Publishing group
DOI: 10.1038/s41541-020-00270-8

Pertussis toxin neutralizing antibody response after an acellular booster vaccination in Dutch and Finnish participants of different age groups

Author(s): Aapo Knuutila, Pauline Versteegen, Alex-Mikael Barkoff, Pieter van Gageldonk, Jussi Mertsola, Guy Berbers, Qiushui He; PERISCOPE Consortium
Published in: Emerging Microbes and Infections, Issue 11/1, 2022, ISSN 2222-1751
Publisher: Nature Publishing Group
DOI: 10.1080/22221751.2022.2053364

Age and Primary Vaccination Background Influence the Plasma Cell Response to Pertussis Booster Vaccination

Author(s): Annieck M. Diks Pauline Versteegen Cristina Teodosio Rick J. Groenland Bas de Mooij Anne-Marie Buisman Alba Torres-Valle Martín Pérez-Andrés Alberto Orfao Guy A. M. Berbers Jacques J. M. van Dongen Magdalena A. Berkowska and on behalf of the IMI-2 PERISCOPE Consortium
Published in: Vaccines, Issue 10(2), 2022, ISSN 2076-393X
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/vaccines10020136

Whole blood based point-of-care assay for the detection of anti-pertussis toxin IgG antibodies

Author(s): Aapo Knuutila, Carita Rautanen, Alex-Mikael Barkoff, Jussi Mertsola, Qiushui He
Published in: Journal of Immunological Methods, Issue 510, 2022, ISSN 0022-1759
Publisher: Elsevier BV
DOI: 10.1016/j.jim.2022.113361

Longitudinal Dynamics of Human B-Cell Response at the Single-Cell Level in Response to Tdap Vaccination

Author(s): Indu Khatri Annieck M. Diks Erik B. van den Akker Liesbeth E. M. Oosten Jaap Jan Zwaginga Marcel J. T. Reinders Jacques J. M. van Dongen and Magdalena A. Berkowska
Published in: Vaccines, 2021, ISSN 2076-393X
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/vaccines9111352

Intranasal inoculation with Bordetella pertussis confers protection without inducing classical whooping cough in baboons

Author(s): Thibaut Naninck, Vanessa Contreras, Loïc Coutte, Sébastien Langlois, Aurelie Hebert-Ribon, Magali Pelletier, Nathalie Reveneau, Camille Locht, Catherine Chapon, Roger Le Grand
Published in: Current Research in Microbial Science, Issue 12/21, 2021, ISSN 2666-5174
Publisher: Elsevier B.V.
DOI: 10.1016/j.crmicr.2021.100072

Responses to an acellular pertussis booster vaccination in children, adolescents, and young and older adults: A collaborative study in Finland, the Netherlands, and the United Kingdom

Author(s): Pauline Versteegen, Marta Valente Pinto, Alex M Barkoff, Pieter G M van Gageldonk, Jan van de Kassteele, Marlies A van Houten, Elisabeth A M Sanders, Ronald de Groot, Dimitri A Diavatopoulos, Sagida Bibi, Raakel Luoto, Qiushui He, Anne-Marie Buisman, Dominic F Kelly, Jussi Mertsola, Guy A M Berbers
Published in: eBioMedicine, 2021, ISSN 2352-3964
Publisher: Elsevier BV
DOI: 10.1016/j.ebiom.2021.103247

Book chapters (1)

The immunology of Bordetella pertussis infection and vaccination

Author(s): Mieszko M. Wilk, Aideen C. Allen, Alicja Misiak, Lisa Borkner, Kingston H.G. Mills
Published in: Pertussis, 2018, Page(s) 42-65, ISBN 9780-198811879
Publisher: Oxford University Press
DOI: 10.1093/oso/9780198811879.003.0003