Objective
Discovered just over 20 years ago, conducting polymers (CPs) have gained considerable attention because of their unique chemical and electronic conducting properties. As a result they have various (bio)analytical and technological applications. CPs are easily synthesised, both chemically and electrochemically under mild conditions, opening up vast possibilities for the immobilisation of biomolecules. Immobilisation of antibodies by entrapment within films or by covalent binding on these films permits the straightforward fabrication of biosensors. In electrochemical biosensors, non-specific binding (NSB) of molecules, e.g. proteins in serum, can occur, lowering overall device performance. In the past, surface chemistry has been employed to prohibit NSB on electrodes with sites that do not have antibodies attached. This surface chemistry however, impairs device performance. CPs have inherent dynamic surface properties that can be easily switched upon the application of an appropriate electrical potential. Their ability to be switched between different oxidation states and the associated switch in properties such as doping level, resistance and surface wettability can be controlled by changing the electrical potential resulting in reversible switching. Routes to nano-dimensional CPs, exhibiting markedly improved properties from those of the bulk materials, have been recently developed. We therefore propose to exploit the dynamic chemical nature of CPs to inhibit NSB in electrochemical bio-assays and demonstrate the efficacy of this approach using a simple nanostructured electrochemical prostate cancer diagnostic platform made from conducting polymers. One can imagine the significance of a biosensor that provides increases in performance and shorter detection times, since the immobilising platform, transducer and dynamic surface control are implemented within a single material.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- medical and health sciences clinical medicine oncology prostate cancer
- engineering and technology electrical engineering, electronic engineering, information engineering electronic engineering sensors biosensors
- natural sciences chemical sciences electrochemistry electrolysis
- natural sciences biological sciences biochemistry biomolecules proteins
- natural sciences chemical sciences polymer sciences
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2007-4-3-IRG
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
GU2 7XH Guildford
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.