Preclinical Intra-Operative Image-Guided Surgery and Post-Operative Radiotherapy of Tumours

Project Information

PRISAR

Grant agreement ID: 644373

DOI

10.3030/644373

Project closed

EC signature date 1 December 2014

Start date 1 February 2015

End date 31 January 2019

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost

€ 2 430 000,00

EU contribution

€ 2 430 000,00

Coordinated by

PERCUROS BV
Netherlands

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (19)

Fluorescence- and multispectral optoacoustic imaging for an optimised detection of deeply located tumours in an orthotopic mouse model of pancreatic carcinoma

Author(s): Joanna Napp, Marieke A. Stammes, Jing Claussen, Hendrica A.J.M. Prevoo, Cornelis F. M. Sier, Freek J. M. Hoeben, Marc S. Robillard, Alexander L. Vahrmeijer, Tim Devling, Alan B. Chan, Lioe-Fee de Geus-Oei, Frauke Alves
Published in: International Journal of Cancer, 2017, ISSN 0020-7136
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/ijc.31236

Pre-clinical Evaluation of a Cyanine-Based SPECT Probe for Multimodal Tumor Necrosis Imaging

Author(s): Marieke A. Stammes, Vicky T. Knol-Blankevoort, Luis J. Cruz, Hans R. I. J. Feitsma, Laura Mezzanotte, Robert A. Cordfunke, Riccardo Sinisi, Elena A. Dubikovskaya, Azusa Maeda, Ralph S. DaCosta, Katja Bierau, Alan Chan, Eric L. Kaijzel, Thomas J. A. Snoeks, Ermond R. van Beek, Clemens W. G. M. Löwik
Published in: Molecular Imaging and Biology, 2016, ISSN 1536-1632
Publisher: Elsevier BV
DOI: 10.1007/s11307-016-0972-7

Preclinical evaluation of near-infrared (NIR) fluorescently labeled Cetuximab as a potential tool for fluorescence-guided surgery

Author(s): Mara Saccomano, Christian Dullin, Frauke Alves, Joanna Napp
Published in: International Journal of Cancer, 2016, ISSN 0020-7136
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/ijc.30277

Ouabain Does Not Induce Selective Spiral Ganglion Cell Degeneration in Guinea Pigs

Author(s): Timo Schomann, Dyan Ramekers, John C. M. J. de Groot, Carola H. van der Ploeg, Ferry G. J. Hendriksen, Stefan Böhringer, Sjaak F. L. Klis, Johan H. M. Frijns, Margriet A. Huisman
Published in: BioMed Research International, Issue 2018, 2018, Page(s) 1-15, ISSN 2314-6133
Publisher: Hindawi Publishing Corporation
DOI: 10.1155/2018/1568414

Imaging bioluminescent exogenous stem cells in the intact guinea pig cochlea

Author(s): Timo Schomann, Laura Mezzanotte, John C.M.J. de Groot, Clemens W.G.M. Löwik, Johan H.M. Frijns, Margriet A. Huisman
Published in: The Anatomical Record, 2019, ISSN 1932-8486
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/ar.24068

Combinatory therapy adopting nanoparticle-based cancer vaccination with immune checkpoint blockade for treatment of post-surgical tumor recurrences

Author(s): Chih Kit Chung, C.G. Da Silva, Dana Kralisch, Alan Chan, Ferry Ossendorp, Luis J. Cruz
Published in: Journal of Controlled Release, Issue 285, 2018, Page(s) 56-66, ISSN 0168-3659
Publisher: Elsevier BV
DOI: 10.1016/j.jconrel.2018.07.011

Automated ischemic lesion segmentation in MRI mouse brain data after transient middle cerebral artery occlusion

Author(s): Inge A. Mulder, Artem Khmelinskii, Oleh Dzyubachyk, Sebastiaan de Jong, Nathalie Rieff, Marieke J. Wermer, Mathias Hoehn, Boudewijn Lelieveldt and Arn M. van den Maagdenberg
Published in: Frontiers in Neuroinformatics, Issue 11:3, 2017, ISSN 1662-453X
Publisher: Frontiers
DOI: 10.3389/fninf.2017.00003

Data-driven identification of prognostic tumor subpopulations using spatially mapped t-SNE of mass spectrometry imaging data

Author(s): Walid M. Abdelmoula, Benjamin Balluff, Sonja Englert, Jouke Dijkstra, Marcel J. T. Reinders, Axel Walch, Liam A. McDonnell, Boudewijn P. F. Lelieveldt
Published in: Proceedings of the National Academy of Sciences, Issue 113/43, 2016, Page(s) 12244-12249, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.1510227113

The Necrosis-Avid Small Molecule HQ4-DTPA as a Multimodal Imaging Agent for Monitoring Radiation Therapy-Induced Tumor Cell Death

Author(s): Marieke A. Stammes, Azusa Maeda, Jiachuan Bu, Deborah A. Scollard, Iris Kulbatski, Philip J. Medeiros, Riccardo Sinisi, Elena A. Dubikovskaya, Thomas J. A. Snoeks, Ermond R. van Beek, Alan B. Chan, Clemens W. G. M. Löwik, Ralph S. DaCosta
Published in: Frontiers in Oncology, Issue 6, 2016, ISSN 2234-943X
Publisher: Frontiers Media S. A.
DOI: 10.3389/fonc.2016.00221

Evaluation of EphA2 and EphB4 as Targets for Image-Guided Colorectal Cancer Surgery

Author(s): Marieke A. Stammes, Hendrica A. J. M. Prevoo, Meyke C. Ter Horst, Stéphanie A. Groot, Cornelis J. H. Van de Velde, Alan B. Chan, Lioe-Fee de Geus-Oei, Peter J. K. Kuppen, Alexander L. Vahrmeijer, Elena B. Pasquale and Cornelis F. M. Sier
Published in: Int. J. Mol. Sci, Issue 2017, 18(2):307, 2017, Page(s) 307, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms18020307

Traumatic Brain Injury: Preclinical Imaging Diagnostic(s) and Therapeutic Approaches

Author(s): Eric L. Kaijzel, Ermond R. van Beek, Marieke A. Stammes, Ivo Que, Alan B. Chan, Clemens W.G.M. Löwik, Luis J. Cruz.
Published in: Current Pharmaceutical Design, Issue 23, 2017, ISSN 1381-6128
Publisher: Bentham Science Publishers
DOI: 10.2174/1381612823666170116141116

Preclinical uPAR-targeted multimodal imaging of locoregional oral cancer

Author(s): M.C. Boonstra, P.B.A.A. Van Driel, S. Keereweer, H.A.J.M. Prevoo, M.A. Stammes, V.M. Baart, C.W.G.M. Löwik, A.P. Mazar, C.J.H. van de Velde, A.L. Vahrmeijer, C.F.M. Sier
Published in: Oral Oncology, 2017, Page(s) 1-8, ISSN 1368-8375
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.oraloncology.2016.12.026

Selecting Targets for Tumor Imaging: An Overview of Cancer-Associated Membrane Proteins

Author(s): Vahrmeijer, Alexander L.; Prevoo, Hendrica A.J.M; Hawinkels, Lukas J.A.C.; Kuppen, Peter J. K.; Boonstra, Martin C.; Cornelis F.M. Sier; de Geus, Susanna W L; van de Velde, Cornelis J.H.
Published in: Biomarkers in Cancer, Vol 2016, Iss 8, Pp 119-133 (2016), Issue 1, 2016, ISSN 1179-299X
Publisher: SAGE Publishing
DOI: 10.4137/BIC.S38542

Intraoperative Bildgebung von Pankreastumoren: Präklinische Validierung von Cetuximab konjugiert an Fluoreszenzfarbstoffe im Nahen Infrarotbereich im orthotopen Pankreastumor-Mausmodell

Author(s): M Saccomano, M Stammes, A Chan, F Alves, J Napp
Published in: Zeitschrift für Gastroenterologie, Issue 54/08, 2016, ISSN 0044-2771
Publisher: Georg Thieme Verlag
DOI: 10.1055/s-0036-1587241

EpCAM as multi-tumour target for near-infrared fluorescence guided surgery

Author(s): Löwik, Clemens; Fish, A.; Lelieveldt, Boudewijn; Dijkstra, Jouke; Cordfunke, R. A.; Tummers, Q.R.J.G.; Driel, Pieter; Vahrmeijer, A. L.; Snoeks, thomas; Velde, Cornelis; Boonstra, M.; Kuppen, P J K; Keereweer, Stijn; Van de Giessen, Martijn; Prevoo, H.A.J.M.; Sier, Cornelis; van Eendenburg, J. D. H.
Published in: B M C Cancer, 16(1), Issue 1, 2016, ISSN 1471-2407
Publisher: BioMed Central
DOI: 10.1186/s12885-016-2932-7

Comprehensive phantom for interventional fluorescence molecular imaging

Author(s): Maria Anastasopoulou, Maximilian Koch, Dimitris Gorpas, Angelos Karlas, Uwe Klemm, Pilar Beatriz Garcia-Allende, Vasilis Ntziachristos
Published in: Journal of Biomedical Optics, Issue 21/9, 2016, Page(s) 091309, ISSN 1083-3668
Publisher: S P I E - International Society for Optical Engineering
DOI: 10.1117/1.JBO.21.9.091309

Hybrid multispectral optoacoustic and ultrasound tomography for morphological and physiological brain imaging

Author(s): Ivan Olefir, Elena Mercep, Neal C. Burton, Saak V. Ovsepian, Vasilis Ntziachristos
Published in: Journal of Biomedical Optics, Issue 21/8, 2016, Page(s) 086005, ISSN 1083-3668
Publisher: S P I E - International Society for Optical Engineering
DOI: 10.1117/1.JBO.21.8.086005

Identification of cell-surface markers for detecting breast cancer cells in ovarian tissue

Author(s): Inge T. A. Peters, Carina G. J. M. Hilders, Cornelis F. M. Sier, Alexander L. Vahrmeijer, Vincent T. H. B. M. Smit, J. Baptist Trimbos, Peter J. K. Kuppen
Published in: Archives of Gynecology and Obstetrics, 2016, ISSN 0932-0067
Publisher: Springer Verlag
DOI: 10.1007/s00404-016-4036-7

Selecting Tumor-Specific Molecular Targets in Pancreatic Adenocarcinoma: Paving the Way for Image-Guided Pancreatic Surgery

Author(s): Susanna W. L. de Geus, Leonora S. F. Boogerd, Rutger-Jan Swijnenburg, J. Sven D. Mieog, Willemieke S. F. J. Tummers, Hendrica A. J. M. Prevoo, Cornelis F. M. Sier, Hans Morreau, Bert A. Bonsing, Cornelis J. H. van de Velde, Alexander L. Vahrmeijer, Peter J. K. Kuppen
Published in: Molecular Imaging and Biology, 2016, Page(s) 1-13, ISSN 1536-1632
Publisher: Elsevier BV
DOI: 10.1007/s11307-016-0959-4

Conference proceedings (1)

Stromal cells as target for image-guided surgery of breast cancer.

Author(s): Sier CF, Bhairosing S, Prevoo HA, van Vlierberghe RL, Hawinkels LJ, Mesker WE, Van de Velde CJ, Kuppen PJ, Vahrmeijer AL
Published in: Cancer Microenvironment, Issue 8 Suppl. 1, 2015, Page(s) 130-131
Publisher: Springer Netherlands
DOI: 10.1007/s12307-015-0175-9