Harnessing Targeted Nanotheranostics to Reprogram Activated Leukocytes in Inflammatory Bowel Disease

Project Information

LeukoTheranostics

Grant agreement ID: 647410

DOI

10.3030/647410

Project closed

EC signature date 20 August 2015

Start date 1 November 2015

End date 31 October 2021

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 703 125,00

EU contribution

€ 2 703 125,00

Coordinated by

TEL AVIV UNIVERSITY
Israel

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (11)

Conformation-sensitive targeting of lipid nanoparticles for RNA therapeutics

Author(s): Niels Dammes, Meir Goldsmith, Srinivas Ramishetti, Jason L. J. Dearling, Nuphar Veiga, Alan B. Packard & Dan Peer
Published in: Nature Nanotechnology, 2021, ISSN 1748-3387
Publisher: Nature Publishing Group
DOI: 10.1038/s41565-021-00928-x

Therapeutic mRNA delivery to leukocytes

Author(s): Granot-Matok Y, Kon E, Dammes N, Mechtinger G, and Peer D
Published in: Journal of controlled release, 2019, ISSN 0168-3659
Publisher: Elsevier BV
DOI: 10.1016/j.jconrel.2019.05.032

Leukocyte-Specific siRNA Delivery Revealing IRF8 as a Potential Anti-Inflammatory Target

Author(s): Veiga N, Goldsmith M, Diesendruck Y, Ramishetti S, Rosenblum D, Elinav E, Behlke MA, Benhar I, and Peer D.
Published in: Journal of controlled release, 2019, ISSN 0168-3659
Publisher: Elsevier BV
DOI: 10.1016/j.jconrel.2019.10.001

rgeted lipid nanoparticles for RNA therapeutics and immunomodulation in leukocytes

Author(s): Veiga N, Diesendruck Y, and Peer D
Published in: Advanced drug delivery reveiws, 2020, ISSN 0169-409X
Publisher: Elsevier BV
DOI: 10.1016/j.addr.2020.04.002

Engineering Lymphocytes with RNAi

Author(s): Ramishetti S, and Peer D
Published in: Advanced drug delivery reveiws, 2018, ISSN 0169-409X
Publisher: Elsevier BV
DOI: 10.1016/j.addr.2018.12.002

Progress and challenges towards targeted delivery of cancer therapeutics

Author(s): Daniel Rosenblum, Nitin Joshi, Wei Tao, Jeffrey M. Karp, Dan Peer
Published in: Nature Communications, Issue 9/1, 2018, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-018-03705-y

A modular platform for targeted RNAi therapeutics

Author(s): Ranit Kedmi, Nuphar Veiga, Srinivas Ramishetti, Meir Goldsmith, Daniel Rosenblum, Niels Dammes, Inbal Hazan-Halevy, Limor Nahary, Shani Leviatan-Ben-Arye, Michael Harlev, Mark Behlke, Itai Benhar, Judy Lieberman, Dan Peer
Published in: Nature Nanotechnology, Issue 13/3, 2018, Page(s) 214-219, ISSN 1748-3387
Publisher: Nature Publishing Group
DOI: 10.1038/s41565-017-0043-5

Cell specific delivery of modified mRNA expressing therapeutic proteins to leukocytes

Author(s): Nuphar Veiga, Meir Goldsmith, Yasmin Granot, Daniel Rosenblum, Niels Dammes, Ranit Kedmi, Srinivas Ramishetti, Dan Peer
Published in: Nature Communications, Issue 9/1, 2018, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-018-06936-1

Immunomodulation of hematological malignancies using oligonucleotides based-nanomedicines

Author(s): Inbal Hazan-Halevy, Dalit Landesman-Milo, Daniel Rosenblum, Shoshy Mizrahy, Brandon D. Ng, Dan Peer
Published in: Journal of Controlled Release, Issue 244, 2016, Page(s) 149-156, ISSN 0168-3659
Publisher: Elsevier BV
DOI: 10.1016/j.jconrel.2016.07.052

Current Progress in Non-viral RNAi-Based Delivery Strategies to Lymphocytes

Author(s): Shoshy Mizrahy, Inbal Hazan-Halevy, Niels Dammes, Dalit Landesman-Milo, Dan Peer
Published in: Molecular Therapy, 2017, ISSN 1525-0016
Publisher: Nature Publishing Group
DOI: 10.1016/j.ymthe.2017.03.001

Monoclonal antibody-based molecular imaging strategies and theranostic opportunities

Author(s): Niels Dammes, Dan Peer
Published in: Theranostics, Issue 10/2, 2020, Page(s) 938-955, ISSN 1838-7640
Publisher: Ivyspring International Publisher
DOI: 10.7150/thno.37443

Intellectual Property Rights

Patent (1)

MODULAR PLATFORM FOR TARGETED THERAPEUTICS

Application/Publication number: PCT/IB 2017/054334
Date: 2017-07-18
Applicant(s): TEL AVIV UNIVERSITY