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Development of Relevant Approaches to Mathematically Model Increasingly Complex Microbially-driven Processes

Objective

Mathematical modelling has played a central role in understanding the fundamental characteristics and behaviour of ecological systems for over a century. In microbial systems, modelling has attempted to reveal the dynamics and interactions of simple co-cultures of organisms in chemostats through to more complex systems with highly diverse functionality. In real-world processes, such as engineered biological systems, EBS, (activated sludge, anaerobic digestion), the former models are incomplete for characterisation of the functional microbial diversity, whereas the latter models are intractable to mathematical analysis, rendering them as inadequate. The Fellowship will investigate the suitability of current mechanistic approaches to modelling for EBS using chemostat theory, but also exploring the analysis of higher dimensional models. The fellow will undertake their outgoing phase at McMaster University to develop their skills in dynamical system theory, applied to real-world systems and observed microbial ecological behaviour in various forms. This will include the use of both analytical and numerical methods to understand system stability and the detection of emergent properties. Recent advances in the understanding of the limits of classical Monod-type growth functions has given rise to new approaches including stochastic and diffusion-based models. However, mathematical investigation of these alternative concepts is not yet fully realised. The fellow will bridge the gap between microbial ecological theory, modelling and mathematical theory to understand the practical possibilities and predictive capabilities that can be exposed when rigorous analysis is achieved. As part of the return phase, he will spend a period at INRA, France, to investigate the validation and application of the models to real systems. This will be continued at Newcastle University, where dissemination of the outputs, including a dedicated software tool will be also be carried out.

Fields of science (EuroSciVoc)

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Programme(s)

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Topic(s)

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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MSCA-IF-GF - Global Fellowships

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) H2020-MSCA-IF-2015

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Coordinator

UNIVERSITY OF NEWCASTLE UPON TYNE
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 255 349,80
Address
KINGS GATE
NE1 7RU Newcastle Upon Tyne
United Kingdom

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Region
North East (England) Northumberland and Tyne and Wear Tyneside
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 255 349,80

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