Objective
Sleep is a fascinating phenomenon and one of the least understood mysteries of biology. It is universal among the animal kingdom and most species devote a large part of their day to sleep, despite the risks of lowering their defenses against predators or not engaging in more productive activities such as foraging or mating.
In many animals, social interaction is a powerful modulator of sleep quality and quantity. In nature, animals are continuously exposed to a diverse variety of stimuli, and interactions with con-specifics represent a particularly relevant set of them. For Drosophila males, interaction with females is key to ensure reproduction, while interaction with other males can create antagonistic fights to compete for sexual partners, food or shelter.
Through this project, I propose to investigate if and how social interactions affect sleep need and sleep quality. Employing fruit flies it has been previously shown that male-male interaction during the night builds up sleep pressure, observable in the next day as marked increase in sleep. Recovery of sleep after sleep deprivation is also called “sleep rebound”, and in all species it is thought to be 1) at the basis of sleep homeostasis and 2) positively correlate with sleep deprivation. The longer an animal stay awake, the higher the sleep pressure and following rebound. Also, it has been described that previous sleep experience modulates antagonistic behaviours between males. Thus, bidirectional interplay between social interaction and sleep appears as a promising framework to address a main goal of modern neuroscience, understand how sleep is regulated and which sleep functions are.
I intend to use new developed behavioural paradigms and software that improve sleep analysis in combination with refined genetic tools available in Drosophila to extend our knowledge on the interaction between phylogenetically conserved behaviours, social interactions and sleep, which have a high impact on reproductive fitness.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- natural sciences biological sciences neurobiology
- natural sciences computer and information sciences software
- medical and health sciences basic medicine physiology homeostasis
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
MAIN PROGRAMME
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H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MSCA-IF-EF-ST - Standard EF
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-MSCA-IF-2015
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
SW7 2AZ LONDON
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.