Chromosomal Condensin Dynamics: From Local Loading to Global Architecture

Project Information

CHROCODYLE

Grant agreement ID: 724482

DOI

10.3030/724482

Project closed

EC signature date 20 December 2016

Start date 1 June 2017

End date 31 May 2023

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 999 599,00

EU contribution

€ 1 999 599,00

Coordinated by

UNIVERSITE DE LAUSANNE
Switzerland

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (12)

DNA-measuring Wadjet SMC ATPases restrict smaller circular plasmids by DNA cleavage

Author(s): Hon Wing Liu, Florian Roisné-Hamelin, Bertrand Beckert, Yan Li, Alexander Myasnikov, Stephan Gruber
Published in: Molecular Cell, 2022, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2022.11.015

DNA segment capture by Smc5/6 holo-complexes.

Author(s): Michael Taschner, Stephan Gruber
Published in: Nature Structural & Molecular Biology, 2023, ISSN 1545-9993
Publisher: Nature Publishing Group
DOI: 10.1038/s41594-023-00956-2

Nse5/6 inhibits the Smc5/6 ATPase and modulates DNA substrate binding

Author(s): Michael Taschner; Jérôme Basquin; Barbara Steigenberger; Ingmar B Schäfer; Young‐Min Soh; Claire Basquin; Esben Lorentzen; Markus Räschle; Richard A Scheltema; Stephan Gruber
Published in: The EMBO Journal, Issue 5, 2021, ISSN 0261-4189
Publisher: Nature Publishing Group
DOI: 10.15252/embj.2021107807

A joint-ParB interface promotes Smc DNA recruitment.

Author(s): Florian P. Bock; Hon Wing Liu; Anna Anchimiuk; Marie-Laure Diebold-Durand; Stephan Gruber
Published in: Cell Reports, Issue 1, 2022, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2022.111273

Structure of Full-Length SMC and Rearrangements Required for Chromosome Organization

Author(s): Marie-Laure Diebold-Durand, Hansol Lee, Laura B. Ruiz Avila, Haemin Noh, Ho-Chul Shin, Haeri Im, Florian P. Bock, Frank Bürmann, Alexandre Durand, Alrun Basfeld, Sihyun Ham, Jérôme Basquin, Byung-Ha Oh, Stephan Gruber
Published in: Molecular Cell, Issue 67/2, 2017, Page(s) 334-347.e5, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2017.06.010

The complete and fully assembled genome sequence of Aeromonas salmonicida subsp. pectinolytica and its comparative analysis with other Aeromonas species: investigation of the mobilome in environmental and pathogenic strains

Author(s): Friedhelm Pfeiffer, Maria-Antonia Zamora-Lagos, Martin Blettinger, Assa Yeroslaviz, Andreas Dahl, Stephan Gruber, Bianca H. Habermann
Published in: BMC Genomics, Issue 19/1, 2018, ISSN 1471-2164
Publisher: BioMed Central
DOI: 10.1186/s12864-017-4301-6

Self-organization of parS centromeres by the ParB CTP hydrolase

Author(s): Young-Min Soh, Iain Finley Davidson, Stefano Zamuner, Jérôme Basquin, Florian Patrick Bock, Michael Taschner, Jan-Willem Veening, Paolo De Los Rios, Jan-Michael Peters, Stephan Gruber
Published in: Science, Issue 366/6469, 2019, Page(s) 1129-1133, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.aay3965

DNA-segment-capture model for loop extrusion by structural maintenance of chromosome (SMC) protein complexes

Author(s): John F Marko, Paolo De Los Rios, Alessandro Barducci, Stephan Gruber
Published in: Nucleic Acids Research, Issue 47/13, 2019, Page(s) 6956-6972, ISSN 0305-1048
Publisher: Oxford University Press
DOI: 10.1093/nar/gkz497

Transient DNA Occupancy of the SMC Interarm Space in Prokaryotic Condensin

Author(s): Roberto Vazquez Nunez, Laura B. Ruiz Avila, Stephan Gruber
Published in: Molecular Cell, Issue 75/2, 2019, Page(s) 209-223.e6, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2019.05.001

Gradual opening of Smc arms in prokaryotic condensin

Author(s): Roberto Vazquez Nunez; Yevhen Polyhach; Young-Min Soh; Gunnar Jeschke; Stephan Gruber
Published in: Cell Reports, 2021, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2021.109051

Relief of ParB autoinhibition by

Author(s): Hammam, Antar; Young-Min, Soh; Stefano, Zamuner; Florian P, Bock; Anna, Anchimiuk; Paolo De Los, Rios; Stephan, Gruber
Published in: Science Advances, Issue 1, 2021, ISSN 2375-2548
Publisher: American Association for the Advancement of Science
DOI: 10.1126/sciadv.abj2854

A low Smc flux avoids collisions and facilitates chromosome organization in Bacillus subtilis

Author(s): Anna Anchimiuk; Virginia S Lioy; Florian Patrick Bock; Anita Minnen; Frederic Boccard; Stephan Gruber
Published in: "eLife, eLife Sciences Publication, 2021, 10, ⟨10.7554/eLife.65467⟩", Issue 3, 2021, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.65467