Hypothalamic mechanisms of thermal homeostasis and adaptation

Project Information

Acclimatize

Grant agreement ID: 772395

DOI

10.3030/772395

Project closed

EC signature date 22 February 2018

Start date 1 September 2018

End date 28 February 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 902 500,00

EU contribution

€ 1 902 500,00

Coordinated by

UNIVERSITATSKLINIKUM HEIDELBERG
Germany

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (5)

Thermally induced neuronal plasticity in the hypothalamus mediates heat tolerance

Author(s): Wojciech Ambroziak, Sara Nencini, Jörg Pohle, Kristina Zuza, Gabriela Pino, Sofia Lundh, Carolina Araujo-Sousa, Larissa I. L. Goetz, Katrin Schrenk-Siemens, Gokul Manoj, Mildred A. Herrera, Claudio Acuna, Jan Siemens
Published in: Nature Neuroscience, Issue 28, 2025, Page(s) 346-360, ISSN 1097-6256
Publisher: Nature Publishing Group
DOI: 10.1038/s41593-024-01830-0

Neuron–astrocyte metabolic coupling facilitates spinal plasticity and maintenance of inflammatory pain

Author(s): Sebastián Marty-Lombardi, Shiying Lu, Wojciech Ambroziak, Katrin Schrenk-Siemens, Jialin Wang, Anna A. DePaoli-Roach, Anna M. Hagenston, Hagen Wende, Anke Tappe-Theodor, Manuela Simonetti, Hilmar Bading, Jürgen G. Okun, Rohini Kuner, Thomas Fleming, Jan Siemens
Published in: Nature Metabolism, Issue 6, 2024, Page(s) 494-513, ISSN 2522-5812
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/s42255-024-01001-2

Astrocytes mediate the effect of oxytocin in the central amygdala on neuronal activity and affective states in rodents

Author(s): Jérôme Wahis, Angel Baudon, Ferdinand Althammer, Damien Kerspern, Stéphanie Goyon, Daisuke Hagiwara, Arthur Lefevre, Lara Barteczko, Benjamin Boury-Jamot, Benjamin Bellanger, Marios Abatis, Miriam Da Silva Gouveia, Diego Benusiglio, Marina Eliava, Andrei Rozov, Ivan Weinsanto, Hanna Sophie Knobloch-Bollmann, Matthew K. Kirchner, Ranjan K. Roy, Hong Wang, Marie Pertin, Perrine Inquimbert, Claudi
Published in: Nature Neuroscience, Issue 24/4, 2021, Page(s) 529-541, ISSN 1097-6256
Publisher: Nature Publishing Group
DOI: 10.1038/s41593-021-00800-0

Diverging roles of TRPV1 and TRPM2 in warm-temperature detection

Author(s): Muad Y Abd El Hay, Gretel B Kamm, Alejandro Tlaie Boria, Jan Siemens
Published in: eLife, Issue 13, 2025, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.95618

A synaptic temperature sensor for body cooling

Author(s): Kamm G B, Boffi J C, Zuza K, Nencini S, Campos J, Schrenk-Siemens K, Sonntag I, Kabaoğlu B, AbdEl Hay M, Schwarz Y, Tappe-Theodor A, Bruns D, Acuna C, Kuner T, Siemens J
Published in: Neuron, Issue Volume 109, October 2020,Issue 20, 2021, Page(s) 3283-3297, ISSN 1097-4199
Publisher: Elsevier
DOI: 10.1016/j.neuron.2021.10.001

Other (1)

TRPM4 keeps up the pace

Author(s): Ambroziak W, Siemens J
Published in: Cell Calcium, 2021
Publisher: Elsevier ltd.
DOI: 10.1016/j.ceca.2021.102401