Epigenome maintenance in response to DNA damage

Project Information

REMIND

Grant agreement ID: 818625

DOI

10.3030/818625

Project closed

EC signature date 27 February 2019

Start date 1 March 2019

End date 28 February 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 738 750,00

EU contribution

€ 1 738 750,00

Coordinated by

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
France

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (11)

New facets in the chromatin-based regulation of genome maintenance

Author(s): Juliette Dabin, Giulia Giacomini, Eliane Petit, Sophie E. Polo
Published in: DNA Repair, Issue 140, 2024, Page(s) 103702, ISSN 1568-7864
Publisher: Elsevier BV
DOI: 10.1016/j.dnarep.2024.103702

Aberrant DNA repair reveals a vulnerability in histone H3.3-mutant brain tumors

Author(s): Giulia Giacomini, Sandra Piquet, Odile Chevallier, Juliette Dabin, Siau-Kun Bai, Byungjin Kim, Robert Siddaway, Brian Raught, Etienne Coyaud, Chun-Min Shan, Robert J D Reid, Takenori Toda, Rodney Rothstein, Viviana Barra, Therese Wilhelm, Sabah Hamadat, Chloé Bertin, Alexander Crane, Frank Dubois, Ignasi Forne, Axel Imhof, Pratiti Bandopadhayay, Rameen Beroukhim, Valeria Naim, Songtao Jia, Cynthi
Published in: Nucleic Acids Research, Issue 52, 2024, Page(s) 2372-2388, ISSN 0305-1048
Publisher: Oxford University Press
DOI: 10.1093/nar/gkad1257

The histone chaperone SPT2 regulates chromatin structure and function in Metazoa

Author(s): Giulia Saredi, Francesco N. Carelli, Stéphane G. M. Rolland, Giulia Furlan, Sandra Piquet, Alex Appert, Luis Sanchez-Pulido, Jonathan L. Price, Pablo Alcon, Lisa Lampersberger, Anne-Cécile Déclais, Navin B. Ramakrishna, Rachel Toth, Thomas Macartney, Constance Alabert, Chris P. Ponting, Sophie E. Polo, Eric A. Miska, Anton Gartner, Julie Ahringer, John Rouse
Published in: Nature Structural & Molecular Biology, Issue 31, 2024, Page(s) 523-535, ISSN 1545-9993
Publisher: Nature Publishing Group
DOI: 10.1038/s41594-023-01204-3

Mitotic chromatin marking governs the segregation of DNA damage

Author(s): Juliette Ferrand, Juliette Dabin, Odile Chevallier, Matteo Kane-Charvin, Ariana Kupai, Joel Hrit, Scott B. Rothbart, Sophie E. Polo
Published in: Nature Communications, Issue 16, 2025, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-025-56090-8

Imaging the response to DNA damage in heterochromatin domains reveals core principles of heterochromatin maintenance

Author(s): Anna Fortuny, Audrey Chansard, Pierre Caron, Odile Chevallier, Olivier Leroy, Olivier Renaud, Sophie E. Polo
Published in: Nature Communications, Issue 12/1, 2021, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-22575-5

DNA Double-Strand Break Repair: All Roads Lead to HeterochROMAtin Marks

Author(s): Pierre Caron, Enrico Pobega, Sophie E. Polo
Published in: Frontiers in Genetics, 2021, ISSN 1664-8021
Publisher: Frontiers Media
DOI: 10.3389/fgene.2021.730696

Histone Variants: Guardians of Genome Integrity

Author(s): Juliette Ferrand, Beatrice Rondinelli, Sophie E. Polo
Published in: Cells, 2020, ISSN 2073-4409
Publisher: MDPI
DOI: 10.3390/cells9112424

The DNA damage response in the chromatin context: A coordinated process

Author(s): Juliette Dabin; Margherita Mori; Sophie E. Polo
Published in: Current Opinin Cell Biol, 2023, ISSN 1879-0410
Publisher: Elsevier
DOI: 10.1016/j.ceb.2023.102176

Control of the chromatin response to DNA damage: Histone proteins pull the strings

Author(s): Juliette Ferrand, Alexandre Plessier, Sophie E. Polo
Published in: Seminars in Cell & Developmental Biology, 2020, ISSN 1084-9521
Publisher: Academic Press
DOI: 10.1016/j.semcdb.2020.07.002

Dissecting regulatory pathways for transcription recovery following DNA damage reveals a non-canonical function of the histone chaperone HIRA

Author(s): Déborah Bouvier, Juliette Ferrand, Odile Chevallier, Michelle T. Paulsen, Mats Ljungman, Sophie E. Polo
Published in: Nature Communications, Issue 12/1, 2021, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-24153-1

Imaging the Response to DNA Damage in Heterochromatin Domains

Author(s): Audrey Chansard, Enrico Pobega, Pierre Caron, Sophie E Polo
Published in: Front Cell Dev Biol, 2022, ISSN 2296-634X
Publisher: Frontiers media
DOI: 10.3389/fcell.2022.920267

Non-peer reviewed articles (1)

Reshaping Chromatin Architecture around DNA Breaks

Author(s): Pierre Caron, Sophie E. Polo
Published in: Trends in Biochemical Sciences, Issue 45/3, 2020, Page(s) 177-179, ISSN 0968-0004
Publisher: Elsevier BV
DOI: 10.1016/j.tibs.2019.12.001

Other (1)

Proteomic profiling of UV damage repair patches uncovers histone chaperones with central functions in chromatin repair

Author(s): Alexandre Plessier, Audrey Chansard, Eliane Petit, Julia Novion Ducassou, Yohann Couté, Sophie E. Polo
Published in: 2024
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2024.08.23.609352