Matching CNS Lineage Maps with Molecular Brain Tumor Portraits for Translational Exploitation

Project Information

BRAIN-MATCH

Grant agreement ID: 819894

DOI

10.3030/819894

Project closed

EC signature date 30 April 2019

Start date 1 May 2019

End date 31 December 2024

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 999 875,00

EU contribution

€ 1 999 875,00

Coordinated by

DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG
Germany

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Open Research Data Pilot (1)

Data management plan

Publications

Other (4)

Gene regulatory network landscape of Group 3/4 medulloblastoma

Author(s): Piyush Joshi, Tamina Stelzer, Konstantin Okonechnikov, Ioannis Sarropoulos, Mari Sepp, Mischan V. Pour-Jamnani, Anne Rademacher, Tetsuya Yamada-Saito, Céline Schneider, Julia Schmidt, Philipp Schäfer, Kevin Leiss, Michele Bortolomeazzi, Jan-Philipp Mallm, Patricia B.G. da Silva, Britta Statz, Andrea Wittmann, Kathrin Schramm, Mirjam Blattner-Johnson, Petra Fiesel, Barbara Jones, Till Milde, Kris
Published in: 2024
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2024.02.09.579680

The evolution of gene regulation in mammalian cerebellum development

Author(s): Ioannis Sarropoulos, Mari Sepp, Tetsuya Yamada, Philipp S. L. Schäfer, Nils Trost, Julia Schmidt, Céline Schneider, Charis Drummer, Sophie Mißbach, Ibrahim I. Taskiran, Nikolai Hecker, Carmen Bravo González-Blas, Niklas Kempynck, Robert Frömel, Piyush Joshi, Evgeny Leushkin, Frederik Arnskötter, Kevin Leiss, Konstantin Okonechnikov, Steven Lisgo, Miklós Palkovits, Svante Pääbo, Margarida
Published in: 2025
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2025.03.14.643248

Medulloblastoma oncogene aberrations are not involved in tumor initiation, but essential for disease progression and therapy resistance

Author(s): Konstantin Okonechnikov, Piyush Joshi, Verena Körber, Anne Rademacher, Michele Bortolomeazzi, Jan-Philipp Mallm, Patricia Benites Goncalves da Silva, Britta Statz, Mari Sepp, Ioannis Sarropoulos, Tetsuya Yamada-Saito, Jan Vaillant, Andrea Wittmann, Kathrin Schramm, Mirjam Blattner-Johnson, Petra Fiesel, Barbara Jones, Till Milde, Kristian Pajtler, Cornelis M. van Tilburg, Olaf Witt, Konrad Bochen
Published in: 2024
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2024.02.09.579690

Cellular development and evolution of the mammalian cerebellum

Author(s): Mari Sepp, Kevin Leiss, Ioannis Sarropoulos, Florent Murat, Konstantin Okonechnikov, Piyush Joshi, Evgeny Leushkin, Noe Mbengue, Céline Schneider, Julia Schmidt, Nils Trost, Lisa Spänig, Peter Giere, Philipp Khaitovich, Steven Lisgo, Miklós Palkovits, Lena M. Kutscher, Simon Anders, Margarida Cardoso-Moreira, Stefan M. Pfister, Henrik Kaessmann
Published in: bioRXiv THE REPRINT SERVER FOR BIOLOGY, 2021, ISSN 2692-8205
Publisher: https://www.biorxiv.org/
DOI: 10.1101/2022.01.05.475171

Peer reviewed articles (4)

Mapping pediatric brain tumors to their origins in the developing cerebellum

Author(s): Konstantin Okonechnikov, Piyush Joshi, Mari Sepp, Kevin Leiss, Ioannis Sarropoulos, Florent Murat, Martin Sill, Pengbo Beck, Kenneth Chun-Ho Chan, Andrey Korshunov, Felix Sah, Maximilian Y Deng, Dominik Sturm, John DeSisto, Andrew M Donson, Nicholas K Foreman, Adam L Green, Giles Robinson, Brent A Orr, Qingsong Gao, Emily Darrow, Jennifer L Hadley, Paul A Northcott, Johannes Gojo, Daisuke Kawauchi
Published in: Neuro-Oncology, Issue 25, 2023, Page(s) 1895-1909, ISSN 1522-8517
Publisher: Duke University Press
DOI: 10.1093/neuonc/noad124

Cellular development and evolution of the mammalian cerebellum

Author(s): Mari Sepp, Kevin Leiss, Florent Murat, Konstantin Okonechnikov, Piyush Joshi, Evgeny Leushkin, Lisa Spänig, Noe Mbengue, Céline Schneider, Julia Schmidt, Nils Trost, Maria Schauer, Philipp Khaitovich, Steven Lisgo, Miklós Palkovits, Peter Giere, Lena M. Kutscher, Simon Anders, Margarida Cardoso-Moreira, Ioannis Sarropoulos, Stefan M. Pfister, Henrik Kaessmann
Published in: Nature, Issue 625, 2024, Page(s) 788-796, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-023-06884-x

Developmental and evolutionary dynamics of cis-regulatory elements in mouse cerebellar cells

Author(s): Ioannis Sarropoulos, Mari Sepp, Robert Frömel, Kevin Leiss, Nils Trost, Evgeny Leushkin, Konstantin Okonechnikov, Piyush Joshi, Peter Giere, Lena M. Kutscher, Margarida Cardoso-Moreira, Stefan M. Pfister, Henrik Kaessmann
Published in: Science, Issue 373, 2024, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.abg4696

Developmental and evolutionary dynamics of cis-regulatory elements in mouse cerebellar cells**

Author(s): Ioannis Sarropoulos; Mari Sepp; Robert Frömel; Kevin Leiss; Nils Trost; Evgeny Leushkin; Konstantin Okonechnikov; Piyush Joshi; Peter Giere; Lena M. Kutscher; Margarida Cardoso-Moreira; Stefan M. Pfister; Henrik Kaessmann
Published in: Science, Issue 1, 2021, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.abg4696