Health effects of cArdiac fluoRoscopy and MOderN radIotherapy in paediatriCs

Project Information

HARMONIC

Grant agreement ID: 847707

DOI

10.3030/847707

Project closed

EC signature date 13 May 2019

Start date 1 June 2019

End date 30 November 2024

Funded under

• Euratom

Total cost

€ 6 999 988,75

EU contribution

€ 6 999 988,75

Coordinated by

FUNDACION PRIVADA INSTITUTO DE SALUD GLOBAL BARCELONA
Spain

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Open Research Data Pilot (1)

Data management plan

Websites, patent fillings, videos etc. (7)

Policy Brief - impact and implications

Policy Brief impact and implications

Factsheet and/or interactive infographic
Website and Project brochure
Newsletter 1
Newsletter 2
Logo
Newsletter 3

Documents, reports (1)

Guidelines for reducing exposure to ionising radiations from imaging studies on paediatric patients

Publications

Peer reviewed articles (23)

Delineation atlas of the Circle of Willis and the large intracranial arteries for evaluation of doses to neurovascular structures in pediatric brain tumor patients treated with radiation therapy

Author(s): L. Toussaint, S. Peters, R. Mikkelsen, S. Karabegovic, C. Bäumer, L. P. Muren, L. Tram-Henriksen, M. Høyer, Y. Lassen-Ramshad & B. Timmermann
Published in: Acta Oncologica, 2021, ISSN 0284-186X
Publisher: Taylor & Francis
DOI: 10.1080/0284186x.2021.1945679

Health effects of ionising radiation in paediatrics undergoing either cardiac fluoroscopy or modern radiotherapy (The HARMONIC project)

Author(s): Isabelle Thierry-Chef; Beate Timmermann; Neige Journy; Marie-Odile Bernier; Richard McNally; Jérémie Dabin; Lorenzo Brualla; Siamak Haghdoost; Adelaida Sarukhan; Karin Haustermans; Inge De Wit; Sofie Isebaert; Yasmin Lassen-Ramshad; Louise Tram Henriksen; Morten Høyer; Laura Toussaint; Guillaume Boissonnat; Juliette Thariat; Charlotte Demoor-Goldschmidt; Nadia Haddy; Stéphanie Bolle; Brice Fre
Published in: EPJ Nuclear Sci. Technol, Issue 5, 2023, ISSN 2491-9292
Publisher: EDP Science
DOI: 10.1051/epjn/2023009

A Longitudinal Study of Individual Radiation Responses in Pediatric Patients Treated with Proton and Photon Radiotherapy, and Interventional Cardiology: Rationale and Research Protocol of the HARMONIC Project

Author(s): Maria Grazia Andreassi,Nadia Haddy,Mats Harms-Ringdahl,Jonica Campolo,Andrea Borghini, François Chevalier, Jochen M. Schwenk, Brice Fresneau, Stephanie Bolle, Manuel Fuentes and Siamak Haghdoost
Published in: International Journal of Molecular Sciences, 2023, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms24098416

Neutron dose and its measurement in proton therapy – Current State of Knowledge

Author(s): Hälg, Roger Antoine; Schneider, Uwe
Published in: British Journal of Radiology, Issue 4, 2020, ISSN 0007-1285
Publisher: British Institute of Radiology
DOI: 10.5167/uzh-181386

The HARMONIC project: Study design for assessment of cancer risks following cardiac fluoroscopy in childhood

Author(s): Richard W Harbron, Isabelle Thierry-Chef, Mark S Pearce, Marie Odile Bernier, Serge Dreuil, Estelle Rage, Maria Grazia Andreassi, Eugenio Picano, Steffen Dreger, Hajo Zeeb, Hilde Olerud, Utheya Thevathas, Kristina Kjaerheim, Gaute Døhlen, Andreas Jahnen, Johannes Hermen, Vadim Chumak, Elena Bakhanova, Vitalii Voloskyi, David Borrego, Choonsik Lee, Jérémie Dabin
Published in: Journal of Radiological Protection, 2020, ISSN 0952-4746
Publisher: Institute of Physics Publishing
DOI: 10.1088/1361-6498/aba66d

The burden of radiation exposure in congenital heart disease: the Italian cohort profile and bioresource collection in HARMONIC project

Author(s): Jonica Campolo, Giuseppe Annoni, Gabriele Vignati, Alessio Peretti, Marco Papa, Paola Enrica Colombo, Gaia Muti, Marina Parolini, Andrea Borghini, Marzia Giaccardi, Lamia Ait-Alì, Eugenio Picano, Maria Grazia Andreassi
Published in: Italian Journal of Pediatrics, Issue 50, 2024, ISSN 1824-7288
Publisher: BMC
DOI: 10.1186/s13052-024-01663-4

Monte Carlo simulation of conical collimators for stereotactic radiosurgery with a 6 MV flattening-filter-free photon beam.

Author(s): M. Hermida-López; David Sánchez-Artuñedo; Miguel Rodriguez; Lorenzo Brualla
Published in: Medical Physics, Issue 5, 2021, ISSN 0094-2405
Publisher: American Association of Physicists in Medicine
DOI: 10.1002/mp.14837

Use of ionizing radiation in a Norwegian cohort of children with congenital heart disease: imaging frequency and radiation dose for the Health Effects of Cardiac Fluoroscopy and Modern Radiotherapy in Pediatrics (HARMONIC) study

Author(s): Susmita Afroz, Bjørn H. Østerås, Utheya S. Thevathas, Gaute Dohlen, Caroline Stokke, Trude E. Robsahm & Hilde M. Olerud
Published in: Pediatric Radiology, 2023, ISSN 0301-0449
Publisher: Springer Verlag
DOI: 10.1007/s00247-023-05774-8

Cumulative radiation dose in children with congenital heart disease: national data 2000–2021, stratified by diagnosis, age, and imaging modality

Author(s): Susmita Afroz, Bjørn H Østerås, Utheya S Thevathas, Lise Heiberg, Trude E Robsahm, Hilde M Olerud, Gaute Dohlen
Published in: Acta Radiologica, 2025, ISSN 0284-1851
Publisher: Taylor & Francis
DOI: 10.1177/02841851251327896

Consistency of Faraday cup and ionization chamber dosimetry of proton fields and the role of nuclear interactions

Author(s): Jörg Wulff, Anne Paul, Claus Maximilian Bäcker, Kilian-Simon Baumann, Johannes Niklas Esser, Benjamin Koska, Beate Timmermann, Nico Gerd Verbeek, Christian Bäumer
Published in: Medical Physics, 2023, ISSN 0094-2405
Publisher: American Association of Physicists in Medicine
DOI: 10.1002/mp.16819

Experiments and Monte Carlo simulations on multiple Coulomb scattering of protons

Author(s): Verbeek, Nico; Wulff, Jörg; Janson, Martin; Bäumer, Christian; Timmermann, Beate; Brualla, Lorenzo
Published in: Medical Physics, Issue 2, 2021, ISSN 0094-2405
Publisher: American Association of Physicists in Medicine
DOI: 10.1002/mp.14860

Monte Carlo Computation of Dose-Volume Histograms in Structures at Risk of an Eye Irradiated with Heterogeneous Ruthenium-106 Plaques

Author(s): Francisco J. Zaragoza, Marion Eichmann, Dirk Flühs, Beate Timmermann, Lorenzo Brualla
Published in: Ocular Oncology and Pathology, Issue 6/5, 2020, Page(s) 353-359, ISSN 2296-4681
Publisher: Karger
DOI: 10.1159/000508113

Complete patient exposure during paediatric brain cancer treatment for photon and proton therapy techniques including imaging procedures

Author(s): Marijke De Saint-Hubert, Guillaume Boissonnat, Uwe Schneider, Christian Bäumer, Nico Verbeek, Johannes Esser, Jörg Wulff, Florian Stuckmann, Finja Suesselbeck, Racell Nabha, Jérémie Dabin, Fabiano Vasi, Stephan Radonic, Miguel Rodriguez, Anne Catherine Simon, Neige Journy, Beate Timmermann, Isabelle Thierry-Chef, Lorenzo Brualla
Published in: Frontiers in oncology, 2023, ISSN 2234-943X
Publisher: Frontiers Media S. A.
DOI: 10.3389/fonc.2023.1222800

Validation of a Monte Carlo Framework for Out-of-Field Dose Calculations in Proton Therapy

Author(s): De Saint-Hubert, Marijke; Verbeek, Nico; Bäumer, Christian; Esser, Johannes; Wulff, Jörg; Nabha, Racell; Van Hoey, Olivier; Dabin, Jérémie; Stuckmann, Florian; Vasi, Fabiano; Radonic, Stephan; Boissonnat, Guillaume; Schneider, Uwe; Rodriguez, Miguel; Timmermann, Beate; Thierry-Chef, Isabelle; Brualla, Lorenzo
Published in: Frontiers in oncology, Issue 1, 2022, ISSN 2234-943X
Publisher: Frontiers Media S. A.
DOI: 10.3389/fonc.2022.882489

Experimental Validation of an Analytical Program and a Monte Carlo Simulation for the Computation of the Far Out-of-Field Dose in External Beam Photon Therapy Applied to Pediatric Patients

Author(s): De Saint-Hubert, Marijke; Suesselbeck, Finja; Vasi, Fabiano; Stuckmann, Florian; Rodriguez, Miguel; Dabin, Jérémie; Timmermann, Beate; Thierry-Chef, Isabelle; Schneider, Uwe; Brualla, Lorenzo
Published in: Frontiers in oncology, Issue 3, 2022, ISSN 2234-943X
Publisher: Frontiers Media S. A.
DOI: 10.3389/fonc.2022.882506

Single pencil beam benchmark of a module for Monte Carlo simulation of proton transport in the PENELOPE code

Author(s): Nico Verbeek, Jörg Wulff, Christian Bäumer, Sabrina Smyczek, Beate Timmermann, Lorenzo Brualla
Published in: Medical Physics, 2020, ISSN 0094-2405
Publisher: American Association of Physicists in Medicine
DOI: 10.1002/mp.14598

Medical applications of ionizing radiation and radiation protection for European patients, population and environment

Author(s): Thierry-Chef, Isabelle; Cardis, Elisabeth; Damilakis, John; Frija, Guy; Hierath, Monika; Hoeschen, Christop; EURAMED ROCC-N-ROLL consortia members
Published in: EPJ Nuclear Sci. Technol, Issue 5, 2022, ISSN 2491-9292
Publisher: EDP Sciences, Springer
DOI: 10.1051/epjn/2022044

Development of whole-body representation and dose calculation in a commercial treatment planning system

Author(s): Pascal Hauri , Stephan Radonic , Fabiano Vasi , Marina Ernst , Marcin Sumila , Matthew M Mille, Choonsik Lee , Matthias Hartmann , Uwe Schneider
Published in: Zeitschrift für Medizinische Physik, 2022, ISSN 0939-3889
Publisher: Urban & Fischer Verlag
DOI: 10.1016/j.zemedi.2021.05.001

Monte Carlo simulation of the Varian TrueBeam flattened‑filtered beams using a surrogate geometry in PRIMO

Author(s): Miguel Rodriguez, Josep Sempau & Lorenzo Brualla
Published in: Radiation Oncology, 2024, ISSN 1748-717X
Publisher: BioMed Central
DOI: 10.1186/s13014-024-02405-w

Monte Carlo verification of the holder correction factors for the radiophotoluminescent glass dosimeter used by the IAEA in international dosimetry audits

Author(s): Josep Sempau; P. Kazantsev; Joanna Izewska; Lorenzo Brualla
Published in: Physica Medica, Issue 7, 2021, ISSN 1120-1797
Publisher: Istituti Editoriali e Poligrafici Internazionali
DOI: 10.1016/j.ejmp.2021.04.014

Assessing late outcomes of advances in radiotherapy for paediatric cancers: study protocol of the “HARMONIC-RT” European registry (NCT 04746729)

Author(s): Neige Journy, Stéphanie Bolle, Lorenzo Brualla, Agnès Dumas, Brice Fresneau, Nadia Haddy, Siamak Haghdoost, Karin Haustermans, Angela Jackson, Sanja Karabegovic, Yasmin Lassen-Ramshad, Juliette Thariat, Martina Roxanne Wette, Suzan Botzenhardt, Inge De Wit, Charlotte Demoor-Goldschmidt, Melissa Christiaens, Morten Høyer, Sofie Isebaert, Sandra Jacobs, Louise Tram Henriksen, John H Maduro, Cecil
Published in: Radiother Oncol, 2023, ISSN 0167-8140
Publisher: Elsevier BV
DOI: 10.1016/j.radonc.2023.109972

European practice on neurovascular late effects after pediatric radiotherapy: considerations on dose planning and follow-up – a HARMONIC/SIOPE ROWG survey

Author(s): Laura Toussaint, Louise Tram Henriksen, Karen Van Beek, Stephanie Bolle, Charlotte Demoor-Goldschmidt, Jenny Gains, Morten Høyer, Geert O. Janssens, Rolf-Dieter Kortmann, Catia Martins Pedro, Beate Timmermann, Katrin Scheinemann, Yasmin Lassen-Ramshad
Published in: Acta Oncologica, Issue 64, 2025, Page(s) 703-707, ISSN 1651-226X
Publisher: MJS Publishing, Medical Journals Sweden AB
DOI: 10.2340/1651-226x.2025.43028

Doses from ionising radiation in paediatric cardiac catheterisations in Norway 1975–2021

Author(s): S Afroz, B H Østerås, Thevethas U S, M Meo, A Jahnen, J Dabin, I Thierry-Chef, T E Robsahm, G Døhlen, H M Olerud
Published in: Journal of Radiological Protection, Issue 44, 2024, Page(s) 041513, ISSN 0952-4746
Publisher: Institute of Physics Publishing
DOI: 10.1088/1361-6498/ad958e

Conference proceedings (1)

Dose reconstruction for pediatric cardiac catheterizations in the 1980s – an input to the epidemiological study HARMONIC

Author(s): H. M. Olerud, U. S. Thevathas, K. Kjærheim, G. Døhlen
Published in: Electronic Presentation Online System (EPOS), 2022
Publisher: ESR - European Society of Radiology
DOI: 10.26044/ecr2022/c-15236