Predicting comorbid cardiovascular disease in individuals with mental disorder by decoding disease mechanisms

CORDIS fournit des liens vers les livrables publics et les publications des projets HORIZON.

Les liens vers les livrables et les publications des projets du 7e PC, ainsi que les liens vers certains types de résultats spécifiques tels que les jeux de données et les logiciels, sont récupérés dynamiquement sur OpenAIRE .

Livrables

Quality Management Plan
Genotyped (chipped) and long range phased Nordic citizens

Genotyped chippeed and long range phased more than one million Nordic citizens M18

Report on dissemination towards industry
Identify interplay between rare and common variants associated with CVD comorbidity in mental illness
Identified rare gene risk variants associated with mental disorders and comorbid CVD
Innovation Management Plan
Report overlap of CVD-mental illness risk genes with body fatty tissue age
Protocols for distributed data analyses

Protocols for distributed data analyses in compliance with ethical, privacy, and GDPR regulations, with scalable technology.

Define non-inherited factors of lifestyle and behaviour
Genes, common/rare variants and pathways/networks associated with CVD-related side effects of antipsychotics/SSRIs

Genes, common/rare variants and pathways/networks associated with CVD-related side effects of antipsychotics/SSRIs.This is a combination of the two deliverables from the original proposal:D5.3 Genes and common/rare variants associated with CVD-related side effects of antipsychotics/SSRIsD5.4 Pathways/networks associated with CVD-related side effects of antipsychotics/SSRIsSince they were similar in scope they were merged in agreement with the Project Officer.

Analysis of a) medication influence and genetic influenc

Analysis of a) medication influence on CVD trajectories for mental disorder patients and b) genetic influence on trajectories in mental disorders and CVD

Report on scientific outreach activities and public outreach activities - M12

Report on scientific outreach activities and public outreach activities. Including information on CoMorMent 6-monthly newsletters.

Validation of stratification tools in re-phenotyped samples

Validation of stratification tools in re-phenotyped samples. A brief description of the achievement.

Report on scientific outreach activities and public outreach activities - M24

Report on scientific outreach activities and public outreach activitiesIncluding information on CoMorMent 6monthly newsletters

Report pharmaceutical targets
IP/Knowledge Management Plan
Dissemination, Exploitation and Communication Plan

Dissemination, Exploitation and Communication Plan and yearly updates. Including a description of CoMorMent website and Social Media channels operational.

Report overlap of CVD-mental illness risk genes with brain age and its genetic architecture

Report overlap of CVDmental illness risk genes with brain age and its genetic architecture

Report of functional mechanisms

A comprehensive report of functional mechanisms

Risk Management Plan
CoMorMent Coordination team established
Analysis of downstream trajectories

Analysis of downstream trajectories in individuals first diagnosed with a mental disorders or b CVD

Report on scientific outreach activities and public outreach activities - M48

Report on scientific outreach activities and public outreach activities - M24.Including information on CoMorMent 6-monthly newsletters.

Definition and harmonization of phenotypic and trajectories data from registries

Infrastructure for coordinated analysis of individual genotypes and phenotypes

Infrastructure for coordinated analysis of individual genotypes and phenotypes from more than one million participants

Analytical tools for imputation and large-scale genotype-phenotype analysis

State-of-the-art analytical tools for imputation and large-scale genotype-phenotype analysis

Data platform for distributed data analysis

A secure data platform for distributed data analysis, including secure computing clusters for each country.

Presentations from the workshop directed at clinical researchers
CoMorMent website and Social Media channels

The CoMorMent website is the key hub for providing detailed dissemination and communication material. The site will feature e.g. abstracts and lay summaries of scientific papers, newsletters, links to articles in popular science publications, and other material as outlined in Sections 2.2.1 and 2.2.5. CoMorMent will exploit social media for both dissemination and communication (Twitter, LinkedIn, Facebook, YouTube) purposes and to direct traffic to the project website. This task entails establishing the project website, Twitter, LinkedIn, Facebook accounts and a YouTube channel. All partners will provide material to be published. The partners will author a lay summary of the partner’s scientific articles for posting on the project website.

Data Management Plan

Tools and code openly available

Make tools and code openly available, incl. documentation for reproducibility

Annual Project Meeting - Y2

Meeting at DECODE Agenda+minutes

Final Project Meeting

Organized by UiO, in BrusselsAgenda + minutes

Annual Project Meeting - Y4

Meeting organized at REGHAgenda+minutes

Annual Project Meeting - Y3

Meeting at UTartuAgenda+minutes

Publications

Cardiovascular-related deaths at the beginning of the COVID-19 outbreak: a prospective analysis based on the UK Biobank

Auteurs: Wang J, Zhu J, Yang H, Hu Y, Sun Y, Ying Z, Qu Y, Valdimarsdottir U, Fang F, Song H.
Publié dans: BMJ open, Numéro 114;5, 2021, ISSN 2044-6055
Éditeur: BMJ Publishing Group
DOI: 10.1136/bmjopen-2020-046931

Mental illness and COVID-19 vaccination: a multinational investigation of observational & register-based data

Auteurs: Mary M. Barker, Kadri Kõiv, Ingibjörg Magnúsdóttir, Hannah Milbourn, Bin Wang, Xinkai Du, Gillian Murphy, Eva Herweijer, Elísabet U. Gísladóttir, Huiqi Li, Anikó Lovik, Anna K. Kähler, Archie Campbell, Maria Feychting, Arna Hauksdóttir, Emily E. Joyce, Edda Bjork Thordardottir, Emma M. Frans, Asle Hoffart, Reedik Mägi, Gunnar Tómasson, Kristjana Ásbjörnsdóttir, Jóhanna Jakobsdótti
Publié dans: Nature Communications, Numéro 15, 2024, ISSN 2041-1723
Éditeur: Nature Publishing Group
DOI: 10.1038/s41467-024-52342-1

Characterising the shared genetic determinants of bipolar disorder, schizophrenia and risk-taking.

Auteurs: Guy Hindley; Guy Hindley; Shahram Bahrami; Nils Eiel Steen; Kevin S. O’Connell; Oleksandr Frei; Oleksandr Frei; Alexey A. Shadrin; Francesco Bettella; Linn Rødevand; Chun Chieh Fan; Chun Chieh Fan; Anders M. Dale; Srdjan Djurovic; Srdjan Djurovic; Olav B. Smeland; Ole A. Andreassen
Publié dans: Translational Psychiatry, Vol 11, Iss 1, Pp 1-10 (2021), Numéro 20, 2021, ISSN 2158-3188
Éditeur: Nature Publishing Group
DOI: 10.1038/s41398-021-01576-4

Deficit of homozygosity among 1.52 million individuals and genetic causes of recessive lethality

Auteurs: Asmundur Oddsson, Patrick Sulem, Gardar Sveinbjornsson, Gudny A. Arnadottir, Valgerdur Steinthorsdottir, Gisli H. Halldorsson, Bjarni A. Atlason, Gudjon R. Oskarsson, Hannes Helgason, Henriette Svarre Nielsen, David Westergaard, Juha M. Karjalainen, Hildigunnur Katrinardottir, Run Fridriksdottir, Brynjar O. Jensson, Vinicius Tragante, Egil Ferkingstad, Hakon Jonsson, Sigurjon A. Gudjonsson, Doruk
Publié dans: Nature Communications, Numéro 14, 2023, ISSN 2041-1723
Éditeur: Nature Publishing Group
DOI: 10.1038/s41467-023-38951-2

Disease trajectories and mortality among individuals diagnosed with depression: a community-based cohort study in UK Biobank

Auteurs: Xin Han, Can Hou, Huazhen Yang, Wenwen Chen, Zhiye Ying, Yao Hu, Yajing Sun, Yuanyuan Qu, Lei Yang, Unnur A. Valdimarsdóttir, Wei Zhang, Haomin Yang, Fang Fang, Huan Song
Publié dans: Molecular Psychiatry, 2021, ISSN 1359-4184
Éditeur: Nature Publishing Group
DOI: 10.1038/s41380-021-01170-6

Thirty novel sequence variants impacting human intracranial volume

Auteurs: Muhammad Sulaman Nawaz, Gudmundur Einarsson, Mariana Bustamante, Rosa S Gisladottir, G Bragi Walters, Gudrun A Jonsdottir, Astros Th Skuladottir, Gyda Bjornsdottir, Sigurdur H Magnusson, Bergrun Asbjornsdottir, Unnur Unnsteinsdottir, Engilbert Sigurdsson, Palmi V Jonsson, Vala Kolbrun Palmadottir, Sigurjon A Gudjonsson, Gisli H Halldorsson, Egil Ferkingstad, Ingileif Jonsdottir, Gudmar Thorleifsso
Publié dans: BRAIN COMMUNICATIONS, Numéro Volume 4, Numéro 6, 2022, Page(s) 1 to 14, ISSN 2632-1297
Éditeur: Oxford academic press
DOI: 10.1093/braincomms/fcac271

Genetic Stratification of Age‐Dependent Parkinson's Disease Risk by Polygenic Hazard Score

Auteurs: Lasse Pihlstrøm, Chun C. Fan, Oleksandr Frei, Manuela Tan, Roshan A. Karunamuni, Cornelis Blauwendraat, Sara Bandres‐Ciga, Ziv Gan‐Or, Donald G. Grosset, null null, Anders M. Dale, Tyler M. Seibert, Ole A. Andreassen
Publié dans: Movement Disorders, Numéro 37, 2023, Page(s) 62-69, ISSN 0885-3185
Éditeur: John Wiley & Sons Inc.
DOI: 10.1002/mds.28808

Pre-pandemic psychiatric disorders and risk of COVID-19: a UK Biobank cohort analysis

Auteurs: Huazhen Yang, Wenwen Chen, Yao Hu, Yilong Chen, Yu Zeng, Yajing Sun, Zhiye Ying, Junhui He, Yuanyuan Qu, Donghao Lu, Fang Fang, Unnur A Valdimarsdóttir, Huan Song
Publié dans: The Lancet Healthy longevity, Numéro 1, 2020, ISSN 2666-7568
Éditeur: Elsevier
DOI: 10.1016/s2666-7568(20)30013-1

Greater male than female variability in regional brain structure across the lifespan

Auteurs: Lara M. Wierenga; Gaelle E. Doucet; Gaelle E. Doucet; Danai Dima; Danai Dima; Ingrid Agartz; Ingrid Agartz; Moji Aghajani; Moji Aghajani; Theophilus N. Akudjedu; Theophilus N. Akudjedu; Anton Albajes-Eizagirre; Dag Alnæs; Dag Alnæs; Kathryn I. Alpert; Ole A. Andreassen; Ole A. Andreassen; Alan Anticevic; Philip Asherson; Tobias Banaschewski; Núria Bargalló; Sarah Baumeister; Ramona Baur-Streub
Publié dans: Human Brain Mapping, Numéro 31, 2022, Page(s) reponame:r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau, ISSN 1065-9471
Éditeur: John Wiley & Sons Inc.
DOI: 10.1002/hbm.25204

Developmental manifestations of polygenic risk for bipolar disorder from infancy to middle childhood

Auteurs: Ragna Bugge Askeland, Laurie J. Hannigan, Kevin S. O’Connell, Elizabeth C. Corfield, Oleksandr Frei, Anita Thapar, George Davey Smith, Ted Reichborn-Kjennerud, Ole A. Andreassen, Helga Ask, Alexandra Havdahl
Publié dans: Translational Psychiatry, Numéro 13, 2023, ISSN 2158-3188
Éditeur: Nature Publishing Group
DOI: 10.1038/s41398-023-02522-2

Sex‐ and age‐specific associations between cardiometabolic risk and white matter brain age in the UK Biobank cohort

Auteurs: Sivaniya Subramaniapillai; Sana Suri; Claudia Barth; Ivan I. Maximov; Irene Voldsbekk; Dennis van der Meer; Tiril P. Gurholt; Dani Beck; Bogdan Draganski; Ole A. Andreassen; Klaus P. Ebmeier; Lars T. Westlye; Ann‐Marie G. de Lange
Publié dans: HBM, Numéro 29, 2022, ISSN 1065-9471
Éditeur: John Wiley & Sons Inc.
DOI: 10.1002/hbm.25882

Cohort Profile: COVIDMENT: COVID-19 cohorts on mental health across six nations

Auteurs: Anna Bára Unnarsdóttir, Anikó Lovik, Chloe Fawns-Ritchie, Helga Ask, Kadri Kõiv, Kristen Hagen, Maria Didriksen, Lea Arregui Nordahl Christoffersen, Alexander Berg Garðarsson, Andrew McIntosh, Anna K Kähler, Archie Campbell, Arna Hauksdóttir, Christian Erikstrup, Dorte Helenius Mikkelsen, Drew Altschul, Edda Bjork Thordardottir, Emma Maria Frans, Gerd Kvale, Gunnar Tómasson, Hanna Maria Ka
Publié dans: Intl Jnl Epidemiology, Numéro 3, 2021, Page(s) e108–e122, ISSN 1464-3685
Éditeur: Oxford University Press
DOI: 10.1093/ije/dyab234

Metabolic Profile and Long-Term Risk of Depression, Anxiety, and Stress-Related Disorders

Auteurs: Charilaos Chourpiliadis, Yu Zeng, Anikó Lovik, Dang Wei, Unnur Valdimarsdóttir, Huan Song, Niklas Hammar, Fang Fang
Publié dans: JAMA Network Open, Numéro 7, 2024, Page(s) e244525, ISSN 2574-3805
Éditeur: JAMA
DOI: 10.1001/jamanetworkopen.2024.4525

Lessons Learned From Neuroimaging Studies of Copy Number Variants: A Systematic Review.

Auteurs: Claudia Modenato; Sandra Martin-Brevet; Clara A. Moreau; Borja Rodriguez-Herreros; Kuldeep Kumar; Bogdan Draganski; Ida E Sønderby; Sébastien Jacquemont
Publié dans: "Biological Psychiatry, Elsevier, 2021, 90 (9), pp.596-610. ⟨10.1016/j.biopsych.2021.05.028⟩", Numéro 4, 2021, ISSN 0006-3223
Éditeur: Elsevier BV
DOI: 10.1016/j.biopsych.2021.05.028

Cardiometabolic risk factors associated with brain age and accelerate brain ageing

Auteurs: Dani Beck; Dani Beck; Ann-Marie Glasø de Lange; Ann-Marie Glasø de Lange; Ann-Marie Glasø de Lange; Mads Lund Pedersen; Mads Lund Pedersen; Dag Alnæs; Dag Alnæs; Ivan I. Maximov; Ivan I. Maximov; Ivan I. Maximov; Irene Voldsbekk; Irene Voldsbekk; Geneviève Richard; Anne-Marthe Sanders; Anne-Marthe Sanders; Kristine Moe Ulrichsen; Kristine Moe Ulrichsen; Erlend S. Dørum; Erlend S. Dørum; Kn
Publié dans: HBM, Numéro 19, 2021, Page(s) 1-21, ISSN 1065-9471
Éditeur: John Wiley & Sons Inc.
DOI: 10.1101/2021.02.25.21252272

Shared genetic architecture between neuroticism, coronary artery disease and cardiovascular risk factors

Auteurs: Kristin Torgersen, Shahram Bahrami, Oleksandr Frei, Alexey Shadrin, Kevin S. O’ Connell, Olav B. Smeland, John Munkhaugen, Srdjan Djurovic, Toril Dammen, Ole A. Andreassen
Publié dans: Translational Psychiatry, Numéro 11, 2022, ISSN 2158-3188
Éditeur: Nature Publishing Group
DOI: 10.1038/s41398-021-01466-9

Distinct biological signature and modifiable risk factors underlie the comorbidity between major depressive disorder and cardiovascular disease

Auteurs: Jacob Bergstedt, Joëlle A. Pasman, Ziyan Ma, Arvid Harder, Shuyang Yao, Nadine Parker, Jorien L. Treur, Dirk J. A. Smit, Oleksandr Frei, Alexey A. Shadrin, Joeri J. Meijsen, Qing Shen, Sara Hägg, Per Tornvall, Alfonso Buil, Thomas Werge, Jens Hjerling-Leffler, Thomas D. Als, Anders D. Børglum, Cathryn M. Lewis, Andrew M. McIntosh, Unnur A. Valdimarsdóttir, Ole A. Andreassen, Patrick F. Sulliva
Publié dans: Nature Cardiovascular Research, Numéro 3, 2024, Page(s) 754-769, ISSN 2731-0590
Éditeur: Springer Nature
DOI: 10.1038/s44161-024-00488-y

Associations between abdominal adipose tissue, reproductive span, and brain characteristics in post-menopausal women

Auteurs: Louise S. Schindler, Sivaniya Subramaniapillai, Claudia Barth, Dennis van der Meer, Mads L. Pedersen, Tobias Kaufmann, Ivan I. Maximov, Jennifer Linge, Olof Dahlqvist Leinhard, Dani Beck, Tiril P. Gurholt, Irene Voldsbekk, Sana Suri, Klaus P. Ebmeier, Bogdan Draganski, Ole A. Andreassen, Lars T. Westlye, Ann-Marie G. de Lange
Publié dans: NeuroImage: clinical, 2022, ISSN 2213-1582
Éditeur: Elsevier BV
DOI: 10.1016/j.nicl.2022.103239

Phenotypically independent profiles relevant to mental health are genetically correlated

Auteurs: Daniel Roelfs, Dag Alnæs, Oleksandr Frei, Dennis van der Meer, Olav B. Smeland, Ole A. Andreassen, Lars T. Westlye, Tobias Kaufmann
Publié dans: Translational Psychiatry, Numéro 11/1, 2021, ISSN 2158-3188
Éditeur: Nature Publishing Group
DOI: 10.1038/s41398-021-01313-x

COSGAP: COntainerized Statistical Genetics Analysis Pipelines

Auteurs: Bayram Cevdet Akdeniz, Oleksandr Frei, Espen Hagen, Tahir Tekin Filiz, Sandeep Karthikeyan, Joëlle Pasman, Andreas Jangmo, Jacob Bergstedt, John R Shorter, Richard Zetterberg, Joeri Meijsen, Ida Elken Sønderby, Alfonso Buil, Martin Tesli, Yi Lu, Patrick Sullivan, Ole A Andreassen, Eivind Hovig
Publié dans: Bioinformatics Advances, Numéro 4, 2024, ISSN 2635-0041
Éditeur: Oxford Academic
DOI: 10.1093/bioadv/vbae067

Poor muscle health and cardiometabolic risks associated with antidepressant treatment

Auteurs: Patrik Andersson, Jennifer Linge, Tiril P. Gurholt, Ida E. Sønderby, Guy Hindley, Ole A. Andreassen, Olof Dahlqvist Leinhard
Publié dans: Obesity, Numéro 32, 2024, Page(s) 1857-1869, ISSN 1930-7381
Éditeur: Wiley-Blackwell
DOI: 10.1002/oby.24085

Patient satisfaction with mental and physical health services: Findings from a UK-wide online survey

Auteurs: Elizabeth J. Kirkham; Sue Fletcher-Watson; Iona Beange; Stella W.Y. Chan; Stephen M. Lawrie
Publié dans: Wellcome Open Research, Numéro 14, 2022, ISSN 1936-1521
Éditeur: Taylor & Francis
DOI: 10.12688/wellcomeopenres.17973.1

Genetic predisposition and antipsychotic treatment effect on metabolic syndrome in schizophrenia: a ten-year follow-up study using the Estonian Biobank

Auteurs: Maris Alver, Silva Kasela, Liina Haring, Laura Birgit Luitva, Krista Fischer, Märt Möls, Lili Milani
Publié dans: The Lancet Regional Health - Europe, Numéro 41, 2024, Page(s) 100914, ISSN 2666-7762
Éditeur: Elsevier
DOI: 10.1016/j.lanepe.2024.100914

Familial factors, diet, and risk of cardiovascular disease: a cohort analysis of the UK Biobank

Auteurs: Hanyue Zhang, Yu Zeng, Huazhen Yang, Yihan Hu, Yao Hu, Wenwen Chen, Zhiye Ying, Yajing Sun, Yuanyuan Qu, Qian Li, Unnur A Valdimarsdóttir, Huan Song,
Publié dans: The American Journal of Clinical Nutrition, Numéro 114;5, 2021, Page(s) 1837-1846, ISSN 0002-9165
Éditeur: American Society for Clinical Nutrition, Inc.
DOI: 10.1093/ajcn/nqab261

No signs of neurodegenerative effects in 15q11.2 BP1-BP2 copy number variant carriers in the UK Biobank

Auteurs: Rune Boen, Tobias Kaufmann, Oleksandr Frei, Dennis van der Meer, Srdjan Djurovic, Ole A. Andreassen, Kaja K. Selmer, Dag Alnæs, Ida E. Sønderby
Publié dans: Translational Psychiatry, Numéro 13, 2023, ISSN 2158-3188
Éditeur: Nature Publishing Group
DOI: 10.1038/s41398-023-02358-w

Genetic liability for schizophrenia and childhood psychopathology in the general population

Auteurs: Laurie J. Hannigan; Ragna Bugge Askeland; Helga Ask; Martin Tesli; Martin Tesli; Elizabeth Corfield; Ziada Ayorech; Øyvind Helgeland; Øyvind Helgeland; Per Magnus; Per Magnus; Pål R. Njølstad; Pål R. Njølstad; Anne-Siri Øyen; Camilla Stoltenberg; Camilla Stoltenberg; Ole A. Andreassen; Ole A. Andreassen; George Davey Smith; Ted Reichborn-Kjennerud; Ted Reichborn-Kjennerud; Alexandra Havdahl
Publié dans: Schizophrenia Bulletin, Numéro 26, 2021, ISSN 0586-7614
Éditeur: Oxford University Press
DOI: 10.1093/schbul/sbaa193

The genetic architecture of the human thalamus and its overlap with ten common brain disorders

Auteurs: Torbjørn Elvsåshagen, Alexey Shadrin, Oleksandr Frei, Dennis van der Meer, Shahram Bahrami, Vinod Jangir Kumar, Olav Smeland, Lars T. Westlye, Ole A. Andreassen, Tobias Kaufmann
Publié dans: Nature Communications, Numéro 12, 2024, ISSN 2041-1723
Éditeur: Nature Publishing Group
DOI: 10.1038/s41467-021-23175-z

A comprehensive map of genetic relationships among diagnostic categories based on 48.6 million relative pairs from the Danish genealogy

Auteurs: Georgios Athanasiadis, Joeri J Meijsen, Dorte Helenius, Andrew J Schork, Andrés Ingason, Wesley K Thompson, Daniel H Geschwind, Thomas Werge, Alfonso Buil
Publié dans: PNAS, Numéro 119, 2022, ISSN 1091-6490
Éditeur: US national academy of sciences
DOI: 10.1073/pnas.2118688119

Finemap-MiXeR: A variational Bayesian approach for genetic finemapping

Auteurs: Bayram Cevdet Akdeniz, Oleksandr Frei, Alexey Shadrin, Dmitry Vetrov, Dmitry Kropotov, Eivind Hovig, Ole A. Andreassen, Anders M. Dale
Publié dans: PLOS Genetics, Numéro 20, 2024, Page(s) e1011372, ISSN 1553-7404
Éditeur: Public Library of Science
DOI: 10.1371/journal.pgen.1011372

Psychometric Properties and Diagnostic Associations of the Short-Form Community Assessment of Psychic Experiences in a Population-Based Sample of 29 021 Adult Men

Auteurs: Viktoria Birkenæs, Nora Refsum Bakken, Evgeniia Frei, Piotr Jaholkowski, Olav B Smeland, Markos Tesfaye, Ingrid Agartz, Ezra Susser, Michaeline Bresnahan, Espen Røysamb, Kjetil Nordbø Jørgensen, Ragnar Nesvåg, Alexandra Havdahl, Ole A Andreassen, Ida Elken Sønderby
Publié dans: Schizophrenia Bulletin, Numéro 49, 2023, Page(s) 1229-1238, ISSN 0586-7614
Éditeur: Oxford University Press
DOI: 10.1093/schbul/sbad074

Mental health indicators in Sweden over a 12-month period during the COVID-19 pandemic – Baseline data of the Omtanke2020 Study

Auteurs: Anikó Lovik; Juan González-Hijón; Anna K. Kähler; Unnur A. Valdimarsdóttir; Emma M. Frans; Patrik K.E. Magnusson; Nancy L. Pedersen; Per Hall; Kamila Czene; Patrick F. Sullivan; Fang Fang
Publié dans: Journal of Affective Disorders, Numéro 10, 2023, ISSN 0165-0327
Éditeur: Elsevier BV
DOI: 10.1016/j.jad.2022.11.004

Plasma Levels of the Cytokines B Cell-Activating Factor (BAFF) and A Proliferation-Inducing Ligand (APRIL) in Schizophrenia, Bipolar, and Major Depressive Disorder: A Cross Sectional, Multisite Study.

Auteurs: John Abel Engh; Thor Ueland; Thor Ueland; Thor Ueland; Ingrid Agartz; Ingrid Agartz; Dimitrios Andreou; Dimitrios Andreou; Pål Aukrust; Pål Aukrust; Birgitte Boye; Birgitte Boye; Erlend Bøen; Ole Kristian Drange; Torbjørn Elvsåshagen; Sigrun Hope; Margrethe Collier Høegh; Inge Joa; Inge Joa; Erik Johnsen; Erik Johnsen; Rune A. Kroken; Rune A. Kroken; Trine Vik Lagerberg; Tove Lekva; Ulrik Fr
Publié dans: 10, Numéro 1, 2022, ISSN 0586-7614
Éditeur: Oxford University Press
DOI: 10.1093/schbul/sbab106

Metabolomic Investigation of Major Depressive Disorder Identifies a Potentially Causal Association With Polyunsaturated Fatty Acids

Auteurs: Eleanor Davyson, Xueyi Shen, Danni A. Gadd, Elena Bernabeu, Robert F. Hillary, Daniel L. McCartney, Mark Adams, Riccardo Marioni, Andrew M. McIntosh
Publié dans: Biological Psychiatry, Numéro 94, 2024, Page(s) 630-639, ISSN 0006-3223
Éditeur: Elsevier BV
DOI: 10.1016/j.biopsych.2023.01.027

Linking sarcopenia, brain structure and cognitive performance: a large-scale UK Biobank study

Auteurs: Tiril P Gurholt, Miguel Germán Borda, Nadine Parker, Vera Fominykh, Rikka Kjelkenes, Jennifer Linge, Dennis van der Meer, Ida E Sønderby, Gustavo Duque, Lars T Westlye, Dag Aarsland, Ole A Andreassen
Publié dans: Brain Communications, Numéro 6, 2024, ISSN 2632-1297
Éditeur: Oxford Academic
DOI: 10.1093/braincomms/fcae083

Additional file 1 of Genetic predispositions to psychiatric disorders and the risk of COVID-19

Auteurs: Chen, Wenwen; Zeng, Yu; Suo, Chen; Yang, Huazhen; Chen, Yilong; Hou, Can; Hu, Yao; Ying, Zhiye; Sun, Yajing; Qu, Yuanyuan; Lu, Donghao; Fang, Fang; Valdimarsdóttir, Unnur A.; Song, Huan
Publié dans: BMC Medicine, Numéro 6, 2022, ISSN 1741-7015
Éditeur: BioMed Central
DOI: 10.6084/m9.figshare.20579734.v1

How important are parents in the development of child anxiety and depression? A genomic analysis of parent-offspring trios in the Norwegian Mother Father and Child Cohort Study (MoBa)

Auteurs: Rosa Cheesman; Espen Moen Eilertsen; Yasmin I. Ahmadzadeh; Line C. Gjerde; Line C. Gjerde; Laurie J. Hannigan; Alexandra Havdahl; Alexander I. Young; Alexander I. Young; Thalia C. Eley; Pål R. Njølstad; Pål R. Njølstad; Per Magnus; Ole A. Andreassen; Ole A. Andreassen; Eivind Ystrom; Eivind Ystrom; Tom A. McAdams; Tom A. McAdams
Publié dans: BMC Medicine, Vol 18, Iss 1, Pp 1-11 (2020), Numéro 27, 2020, ISSN 1741-7015
Éditeur: BioMed Central
DOI: 10.1101/2020.04.14.20064782

Genetic predispositions to psychiatric disorders and the risk of COVID-19

Auteurs: Wenwen Chen; Yu Zeng; Chen Suo; Huazhen Yang; Yilong Chen; Can Hou; Yao Hu; Zhiye Ying; Yajing Sun; Yuanyuan Qu; Donghao Lu; Fang Fang; Unnur A. Valdimarsdóttir; Huan Song
Publié dans: BMC Medicine, Numéro 5, 2022, ISSN 1741-7015
Éditeur: BioMed Central
DOI: 10.1186/s12916-022-02520-z

Polygenic risk for schizophrenia and bipolar disorder in relation to cardiovascular biomarkers

Auteurs: Elina J. Reponen, Thor Ueland, Jaroslav Rokicki, Francesco Bettella, Monica Aas, Maren C. F. Werner, Ingrid Dieset, Nils E. Steen, Ole A. Andreassen, Martin Tesli
Publié dans: European Archives of Psychiatry and Clinical Neuroscience, Numéro 274, 2024, Page(s) 1223-1230, ISSN 0940-1334
Éditeur: Dr. Dietrich Steinkopff Verlag
DOI: 10.1007/s00406-023-01591-0

Considerations on brain age predictions from repeatedly sampled data across time

Auteurs: Max Korbmacher, Meng-Yun Wang, Rune Eikeland, Ralph Buchert, Ole A. Andreassen, Thomas Espeseth, Esten Leonardsen, Lars T. Westlye, Ivan I. Maximov, Karsten Specht
Publié dans: Brain and Behaviour, 2024, ISSN 2162-3279
Éditeur: Wiley
DOI: 10.1101/2023.03.31.535038

How important are parents in the development of child anxiety and depression? A genomic analysis of parent-offspring trios in the Norwegian Mother Father and Child Cohort Study (MoBa)

Auteurs: Rosa Cheesman, Espen Moen Eilertsen, Yasmin I. Ahmadzadeh, Line C. Gjerde, Laurie J. Hannigan, Alexandra Havdahl, Alexander I. Young, Thalia C. Eley, Pål R. Njølstad, Per Magnus, Ole A. Andreassen, Eivind Ystrom, Tom A. McAdams
Publié dans: BMC Medicine, Numéro 18, 2021, ISSN 1741-7015
Éditeur: BioMed Central
DOI: 10.1186/s12916-020-01760-1

Heart rate variability is associated with disease severity in psychosis spectrum disorders.

Auteurs: Beatrice R. Benjamin; Mathias Valstad; Torbjørn Elvsåshagen; Erik G. Jönsson; Torgeir Moberget; Adriano Winterton; Marit Haram; Margrethe Collier Høegh; Trine Vik Lagerberg; Nils Eiel Steen; Lars Erik Larsen; Ole A. Andreassen; Lars T. Westlye; Daniel Quintana
Publié dans: Progress in Neuro-Psychopharmacology and Biological Psychiatry, Numéro 17, 2021, ISSN 0278-5846
Éditeur: Elsevier BV
DOI: 10.1016/j.pnpbp.2020.110108

Bidirectional genetic overlap between autism spectrum disorder and cognitive traits

Auteurs: Sigrun Hope, Alexey A. Shadrin, Aihua Lin, Shahram Bahrami, Linn Rødevand, Oleksandr Frei, Saira J. Hübenette, Weiqiu Cheng, Guy Hindley, Heidi Nag, Line Ulstein, Magdalena Efrim-Budisteanu, Kevin O’Connell, Anders M. Dale, Srdjan Djurovic, Terje Nærland, Ole A. Andreassen
Publié dans: Translational Psychiatry, Numéro 13, 2023, ISSN 2158-3188
Éditeur: Nature Publishing Group
DOI: 10.1038/s41398-023-02563-7

Assessing causal links between age at menarche and adolescent mental health: a Mendelian randomisation study

Auteurs: Adrian Dahl Askelund, Robyn E. Wootton, Fartein A. Torvik, Rebecca B. Lawn, Helga Ask, Elizabeth C. Corfield, Maria C. Magnus, Ted Reichborn-Kjennerud, Per M. Magnus, Ole A. Andreassen, Camilla Stoltenberg, George Davey Smith, Neil M. Davies, Alexandra Havdahl, Laurie J. Hannigan
Publié dans: BMC Medicine, Numéro 22, 2024, ISSN 1741-7015
Éditeur: BioMed Central
DOI: 10.1186/s12916-024-03361-8

Increased circulating IL-18 levels in severe mental disorders indicate systemic inflammasome activation.

Auteurs: Attila Szabo; Kevin S O' Connell; Thor Ueland; Thor Ueland; Thor Ueland; Mashhood Ahmed Sheikh; Ingrid Agartz; Ingrid Agartz; Dimitrios Andreou; Dimitrios Andreou; Pål Aukrust; Pål Aukrust; Birgitte Boye; Birgitte Boye; Erlend Bøen; Ole Kristian Drange; Torbjørn Elvsåshagen; Torbjørn Elvsåshagen; John Abel Engh; Sigrun Hope; Margrethe Collier Høegh; Inge Joa; Inge Joa; Erik Johnsen; Erik J
Publié dans: Brain, behavior, and immunity, Numéro 4, 2022, Page(s) 299-306, ISSN 0889-1591
Éditeur: Academic Press
DOI: 10.1016/j.bbi.2021.10.017

Polygenic overlap and shared genetic loci between loneliness, severe mental disorders, and cardiovascular disease risk factors suggest shared molecular mechanisms

Auteurs: Linn Rødevand, Shahram Bahrami, Oleksandr Frei, Aihua Lin, Osman Gani, Alexey Shadrin, Olav B. Smeland, Kevin S. O’ Connell, Torbjørn Elvsåshagen, Adriano Winterton, Daniel S. Quintana, Guy F. L. Hindley, Maren C. F. Werner, Srdjan Djurovic, Anders M. Dale, Trine V. Lagerberg, Nils Eiel Steen, Ole A. Andreassen
Publié dans: Translational Psychiatry, Numéro 11/1, 2021, ISSN 2158-3188
Éditeur: Nature Publishing Group
DOI: 10.1038/s41398-020-01142-4

The link between liver fat and cardiometabolic diseases is highlighted by genome-wide association study of MRI-derived measures of body composition

Auteurs: Dennis van der Meer, Tiril P. Gurholt, Ida E. Sønderby, Alexey A. Shadrin, Guy Hindley, Zillur Rahman, Ann-Marie G. de Lange, Oleksandr Frei, Olof D. Leinhard, Jennifer Linge, Rozalyn Simon, Dani Beck, Lars T. Westlye, Sigrun Halvorsen, Anders M. Dale, Tom H. Karlsen, Tobias Kaufmann, Ole A. Andreassen
Publié dans: Communications Biology, Numéro 5, 2022, ISSN 2399-3642
Éditeur: Nature portfolio
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What we learn about bipolar disorder from large‐scale neuroimaging: Findings and future directions from the <scp>ENIGMA</scp> Bipolar Disorder Working Group

Auteurs: Christopher R. K. Ching, Derrek P. Hibar, Tiril P. Gurholt, Abraham Nunes, Sophia I. Thomopoulos, Christoph Abé, Ingrid Agartz, Rachel M. Brouwer, Dara M. Cannon, Sonja M. C. de Zwarte, Lisa T. Eyler, Pauline Favre, Tomas Hajek, Unn K. Haukvik, Josselin Houenou, Mikael Landén, Tristram A. Lett, Colm McDonald, Leila Nabulsi, Yash Patel, Melissa E. Pauling, Tomas Paus, Joaquim Radua, Marcio G. Soe
Publié dans: Human Brain Mapping, Numéro 43, 2023, Page(s) 56-82, ISSN 1065-9471
Éditeur: John Wiley & Sons Inc.
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Genome-by-Trauma Exposure Interactions in Adults With Depression in the UK Biobank

Auteurs: Melisa Chuong, Mark J. Adams, Alex S. F. Kwong, Chris S. Haley, Carmen Amador, Andrew M. McIntosh
Publié dans: JAMA Psychiatry, Numéro 79, 2022, Page(s) 1110, ISSN 2168-622X
Éditeur: American Medical Association
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Experience of clinical services shapes attitudes to mental health data sharing: findings from a UK-wide survey

Auteurs: E. J. Kirkham; S. M. Lawrie; C. J. Crompton; M. H. Iveson; N. D. Jenkins; J. Goerdten; I. Beange; S. W. Y. Chan; A. McIntosh; S. Fletcher-Watson
Publié dans: BMC public health, 22(1):357, Numéro 9, 2022, ISSN 1471-2458
Éditeur: BioMed Central
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Quantifying the relative importance of genetics and environment on the comorbidity between mental and cardiometabolic disorders using 17 million Scandinavians

Auteurs: Joeri Meijsen, Kejia Hu, Morten D. Krebs, Georgios Athanasiadis, Sarah Washbrook, Richard Zetterberg, Raquel Nogueira Avelar e Silva, John R. Shorter, Jesper R. Gådin, Jacob Bergstedt, David M. Howard, Weimin Ye, Yi Lu, Unnur A. Valdimarsdóttir, Andrés Ingason, Dorte Helenius, Oleguer Plana-Ripoll, John J. McGrath, Nadia Micali, Ole A. Andreassen, Thomas M. Werge, Fang Fang, Alfonso Buil
Publié dans: Nature Communications, Numéro 15, 2024, ISSN 2041-1723
Éditeur: Nature Publishing Group
DOI: 10.1038/s41467-024-49507-3

Extensive bidirectional genetic overlap between bipolar disorder and cardiovascular disease phenotypes

Auteurs: Linn Rødevand, Shahram Bahrami, Oleksandr Frei, Yunhan Chu, Alexey Shadrin, Kevin S. O’Connell, Olav B. Smeland, Torbjørn Elvsåshagen, Guy F. L. Hindley, Srdjan Djurovic, Anders M. Dale, Trine V. Lagerberg, Nils Eiel Steen, Ole A. Andreassen
Publié dans: Translational Psychiatry, Numéro 11/1, 2021, ISSN 2158-3188
Éditeur: Nature Publishing Group
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Characterizing the polygenic overlap and shared loci between rheumatoid arthritis and cardiovascular diseases

Auteurs: Xiaohui Sun, Yu Qian, Weiqiu Cheng, Ding Ye, Bin Liu, Dan Zhou, Chengping Wen, Ole A. Andreassen, Yingying Mao
Publié dans: BMC Medicine, Numéro 22, 2024, ISSN 1741-7015
Éditeur: BioMed Central
DOI: 10.1186/s12916-024-03376-1

Population-based body–brain mapping links brain morphology with anthropometrics and body composition

Auteurs: Tiril P. Gurholt, Tobias Kaufmann, Oleksandr Frei, Dag Alnæs, Unn K. Haukvik, Dennis van der Meer, Torgeir Moberget, Kevin S. O’Connell, Olof D. Leinhard, Jennifer Linge, Rozalyn Simon, Olav B. Smeland, Ida E. Sønderby, Adriano Winterton, Nils Eiel Steen, Lars T. Westlye, Ole A. Andreassen
Publié dans: Translational Psychiatry, Numéro 11/1, 2021, ISSN 2158-3188
Éditeur: Nature Publishing Group
DOI: 10.1038/s41398-021-01414-7

Body mass index and childhood symptoms of depression, anxiety, and attention-deficit hyperactivity disorder: A within-family Mendelian randomization study

Auteurs: Amanda M Hughes; Eleanor Sanderson; Tim Morris; Ziada Ayorech; Martin Tesli; Helga Ask; Ted Reichborn-Kjennerud; Ole A Andreassen; Per Magnus; Øyvind Helgeland; Stefan Johansson; Pål Njølstad; George Davey Smith; Alexandra Havdahl; Laura D Howe; Neil M Davies
Publié dans: eLife, Numéro 24, 2022, ISSN 2050-084X
Éditeur: eLife Sciences Publications
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The shared genetic basis of mood instability and psychiatric disorders: A cross-trait genome-wide association analysis

Auteurs: Guy Hindley; Kevin S. O'Connell; Zillur Rahman; Oleksandr Frei; Shahram Bahrami; Alexey Shadrin; Margrethe C. Høegh; Weiqiu Cheng; Naz Karadag; Aihua Lin; Linn Rødevand; Chun C. Fan; Srdjan Djurovic; Trine V. Lagerberg; Anders M. Dale; Olav B. Smeland; Ole A. Andreassen
Publié dans: AMERICAN JOURNAL OF MEDICAL GENETICS, Numéro 4, 2022, ISSN 1552-4841
Éditeur: Wiley-Liss Inc
DOI: 10.1002/ajmg.b.32907

Cardiovascular disease and subsequent risk of psychiatric disorders: a nationwide sibling-controlled study

Auteurs: Qing Shen, Huan Song, Thor Aspelund, Jingru Yu, Donghao Lu, Jóhanna Jakobsdóttir, Jacob Bergstedt, Lu Yi, Patrick Sullivan, Arvid Sjölander, Weimin Ye, Katja Fall, Fang Fang, Unnur Valdimarsdóttir
Publié dans: eLife, Numéro 11, 2022, ISSN 2050-084X
Éditeur: eLife Sciences Publications
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Using a knowledge exchange event to assess study participants’ attitudes to research in a rapidly evolving research context

Auteurs: Iona Beange, Elizabeth J. Kirkham, Sue Fletcher-Watson, Matthew H. Iveson, Stephen M. Lawrie, G. David Batty, James P. Boardman, Ian J. Deary, Corri Black, David J. Porteous, Andrew M. McIntosh
Publié dans: Wellcome Open Research, Numéro 5, 2020, Page(s) 24, ISSN 2398-502X
Éditeur: Welcome Open Research
DOI: 10.12688/wellcomeopenres.15651.2

Effects of copy number variations on brain structure and risk for psychiatric illness: Large‐scale studies from the ENIGMA working groups on CNVs

Auteurs: Ida E. Sønderby, Christopher R. K. Ching, Sophia I. Thomopoulos, Dennis Meer, Daqiang Sun, Julio E. Villalon‐Reina, Ingrid Agartz, Katrin Amunts, Celso Arango, Nicola J. Armstrong, Rosa Ayesa‐Arriola, Geor Bakker, Anne S. Bassett, Dorret I. Boomsma, Robin Bülow, Nancy J. Butcher, Vince D. Calhoun, Svenja Caspers, Eva W. C. Chow, Sven Cichon, Simone Ciufolini, Michael C. Craig, Benedicto Cres
Publié dans: Human Brain Mapping, 2021, Page(s) online ahead of print, ISSN 1065-9471
Éditeur: John Wiley & Sons Inc.
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Cohort Profile Update: Mental Health Online Survey in the Estonian Biobank (EstBB MHoS)

Auteurs: Triinu Ojalo, Elis Haan, Kadri Kõiv, Hanna Maria Kariis, Kristi Krebs, Helen Uusberg, Tuuli Sedman, Urmo Võsa, Mairo Puusepp, Sirje Lind, Innar Hallik, Helene Alavere, null null, Andres Metspalu, Tõnu Esko, Reedik Mägi, Mari Nelis, Georgi Hudjashov, Lili Milani, Kelli Lehto
Publié dans: International Journal of Epidemiology, Numéro 53, 2024, ISSN 0300-5771
Éditeur: Oxford University Press
DOI: 10.1093/ije/dyae017

Short-term improvement of mental health after a COVID-19 vaccination

Auteurs: Charilaos Chourpiliadis, Anikó Lovik, Anna K. Kähler, Unnur A. Valdimarsdóttir, Emma M. Frans, Fredrik Nyberg, Patrick F. Sullivan, Fang Fang
Publié dans: PLOS ONE, 2024, ISSN 1932-6203
Éditeur: Public Library of Science
DOI: 10.1101/2022.02.22.22271327

Co-development of a Best Practice Checklist for Mental Health Data Science: A Delphi Study

Auteurs: Elizabeth J. Kirkham, Catherine J. Crompton, Matthew H. Iveson, Iona Beange, Andrew M. McIntosh, Sue Fletcher-Watson
Publié dans: Frontiers in Psychiatry, Numéro 12, 2021, ISSN 1664-0640
Éditeur: Frontiers Research Foundation
DOI: 10.3389/fpsyt.2021.643914

Sex differences in autonomic adverse effects related to antipsychotic treatment and associated hormone profiles

Auteurs: Ingrid T. Johansen, Nils Eiel Steen, Linn Rødevand, Synve H. Lunding, Gabriela Hjell, Monica B. E. G. Ormerod, Ingrid Agartz, Ingrid Melle, Trine V. Lagerberg, Mari Nerhus, Ole A. Andreassen
Publié dans: Schizophrenia, Numéro 10, 2024, ISSN 2754-6993
Éditeur: Nature publishing
DOI: 10.1038/s41537-023-00430-4

The role of genetic predisposition in cardiovascular risk after cancer diagnosis: a matched cohort study of the UK Biobank

Auteurs: Huazhen Yang, Yu Zeng, Wenwen Chen, Yajing Sun, Yao Hu, Zhiye Ying, Junren Wang, Yuanyuan Qu, Fang Fang, Unnur A. Valdimarsdóttir & Huan Song
Publié dans: British journal of cancer, Numéro 9, 2022, Page(s) 1650-1659, ISSN 0007-0920
Éditeur: Nature Publishing Group
DOI: 10.1038/s41416-022-01935-y

Depressive symptom trajectories among general population during the COVID-19 pandemic in Iceland: a prospective cohort study (2020–2023)

Auteurs: Yue Wang, Arna Hauksdóttir, Edda Bjork Thordardottir, Fenfen Ge, Elísabet Unnur Gísladóttir, Jóhanna Jakobsdóttir, Kristjana Hrönn Ásbjörnsdóttir, Harpa Rúnarsdóttir, Anna Bára Unnarsdóttir, Ingibjörg Magnúsdóttir, Thorvardur Jon Love, Sigurdur Yngvi Kristinsson, Runolfur Palsson, Helga Zoega, Fang Fang, Gunnar Tómasson, Huan Song, Thor Aspelund, Unnur Valdimarsdottir
Publié dans: BMJ Public Health, Numéro 2, 2024, Page(s) e001294, ISSN 2753-4294
Éditeur: BMJ Public Health
DOI: 10.1136/bmjph-2024-001294

COVID-19 illness severity and 2-year prevalence of physical symptoms: an observational study in Iceland, Sweden, Norway and Denmark

Auteurs: Qing Shen, Emily E. Joyce, Omid V. Ebrahimi, Maria Didriksen, Anikó Lovik, Karen Sól Sævarsdóttir, Ingibjörg Magnúsdóttir, Dorte Helenius Mikkelsen, Anna Bára Unnarsdóttir, Arna Hauksdóttir, Asle Hoffart, Anna K. Kähler, Edda Björk Thórdardóttir, Elías Eythórsson, Emma M. Frans, Gunnar Tómasson, Helga Ask, Hrönn Hardardóttir, Jóhanna Jakobsdóttir, Kelli Lehto, Li Lu, Ole A. An
Publié dans: The Lancet Regional Health - Europe, Numéro 35, 2023, Page(s) 100756, ISSN 2666-7762
Éditeur: Elsevier
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Elevated symptoms of depression and anxiety among family members and friends of critically ill COVID-19 patients

Auteurs: Lovik, A.; González-Hijón, J.; , Hoffart, A.; Fawns-Ritchie, C.; Magnúsdóttir, I.; Lu, L.; Unnarsdóttir Bára, A.; Kähler, A. K.; Campbell, A.; Hauksdóttir, A.; Chourpiliadis, C.; McCartney, D.L.; Thordardóttir E.B.; Joyce, E.E.; Frans E.M.; Jakobsdóttir, J.; Trogstad, L.; Andreassen, O.A., Magnus, P.; Johnson, S.U.; Sullivan, P.F.; Aspelund, T.; Porteous, D.J.; Ask, H.; Ebrahimi, O.V.; V
Publié dans: The Lancret Regional Health, Numéro 2, 2023, ISSN 2666-7762
Éditeur: Lancet

Lifetime exposure to violence and other life stressors and hair cortisol concentration in women

Auteurs: Rebekka Lynch, Thor Aspelund, Matthías Kormáksson, Mario H. Flores-Torres, Arna Hauksdóttir, Filip K. Arnberg, Martín Lajous, Clemens Kirschbaum & Unnur Valdimarsdóttir
Publié dans: The International Journal on the Biology of Stress, Numéro 25, 2022, Page(s) 48-56, ISSN 1025-3890
Éditeur: Taylor & Francis
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Genetic propensities for verbal and spatial ability have opposite effects on body mass index and risk of schizophrenia

Auteurs: Gudrun A. Jonsdottir, Gudmundur Einarsson, Gudmar Thorleifsson, Sigurdur H. Magnusson, Arni F. Gunnarsson, Michael L. Frigge, Rosa S. Gisladottir, Unnur Unnsteinsdottir, Bjarni Gunnarsson, G. Bragi Walters, Valgerdur Steinthorsdottir, Anna Helgadottir, Ingileif Jonsdottir, Thorsteinn Gislason, Haraldur S. Thorsteinsson, Engilbert Sigurdsson, Magnus Haraldsson, Emil L. Sigurdsson, Ragnar Bjarnason,
Publié dans: Intelligence, Numéro 88, 2021, Page(s) 101565, ISSN 0160-2896
Éditeur: Elsevier BV
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Elevated symptoms of depression and anxiety among family members and friends of critically ill COVID-19 patients – an observational study of five cohorts across four countries

Auteurs: Anikó Lovik, Juan González-Hijón, Asle Hoffart, Chloe Fawns-Ritchie, Ingibjörg Magnúsdóttir, Li Lu, Anna Bára Unnarsdóttir, Anna K. Kähler, Archie Campbell, Arna Hauksdóttir, Charilaos Chourpiliadis, Daniel L. McCartney, Edda Björk Thordardóttir, Emily E. Joyce, Emma M. Frans, Jóhanna Jakobsdóttir, Lill Trogstad, Ole A. Andreassen, Per Magnus, Sverre Urnes Johnson, Patrick F. Sulliva
Publié dans: The Lancet Regional Health - Europe, Numéro 33, 2024, Page(s) 100733, ISSN 2666-7762
Éditeur: Lancet
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Auteurs: Fan Tian, Fang Fang, Qing Shen, Weimin Ye, Unnur A. Valdimarsdóttir, Huan Song
Publié dans: European Journal of Epidemiology, Numéro 37, 2022, Page(s) 947-958, ISSN 0393-2990
Éditeur: Kluwer Academic Publishers
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History of childhood maltreatment associated with hospitalization or death due to COVID-19: a cohort study

Auteurs: Yue Wang, Fenfen Ge, Thor Aspelund, Helga Ask, Arna Hauksdóttir, Kejia Hu, Jóhanna Jakobsdóttir, Helga Zoega, Qing Shen, Heather C. Whalley, Ole Birger Vesterager Pedersen, Kelli Lehto, Ole A. Andreassen, Fang Fang, Huan Song, Unnur A. Valdimarsdóttir
Publié dans: BMC Medicine, Numéro 22, 2024, ISSN 1741-7015
Éditeur: BioMed Central
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Using Polygenic Hazard Scores to Predict Age at Onset of Alzheimer’s Disease in Nordic Populations

Auteurs: Ehsan Motazedi, Weiqiu Cheng, Jesper Q. Thomassen, Oleksandr Frei, Arvid Rongve, Lavinia Athanasiu, Shahram Bahrami, Alexey Shadrin, Ingun Ulstein, Eystein Stordal, Anne Brækhus, Ingvild Saltvedt, Sigrid B. Sando, Kevin S. O’Connell, Guy Hindley, Dennis van der Meer, Sverre Bergh, Børge G. Nordestgaard, Anne Tybjærg-Hansen, Geir Bråthen, Lasse Pihlstrøm, Srdjan Djurovic, Ruth Frikke-Schmidt
Publié dans: Journal of Alzheimer’s Disease, Numéro 88, 2025, Page(s) 1533-1544, ISSN 1387-2877
Éditeur: IOS Press
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The role of depression and antidepressant treatment in antihypertensive medication adherence and persistence: Utilising electronic health record data

Auteurs: Hanna Maria Kariis, Silva Kasela, Tuuli Jürgenson, Aet Saar, Jana Lass, Kristi Krebs, Urmo Võsa, Elis Haan, Lili Milani, Kelli Lehto
Publié dans: Journal of Psychiatric Research, Numéro 168, 2023, Page(s) 269-278, ISSN 0022-3956
Éditeur: Pergamon Press Ltd.
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Boosting Schizophrenia Genetics by Utilizing Genetic Overlap With Brain Morphology

Auteurs: Dennis van der Meer, Alexey A. Shadrin, Kevin O’Connell, Francesco Bettella, Srdjan Djurovic, Thomas Wolfers, Dag Alnæs, Ingrid Agartz, Olav B. Smeland, Ingrid Melle, Jennifer Monereo Sánchez, David E.J. Linden, Anders M. Dale, Lars T. Westlye, Ole A. Andreassen, Oleksandr Frei, Tobias Kaufmann
Publié dans: Biological psychiatry, Numéro vol 92, no. 4, 2022, ISSN 0006-3223
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Depression, anxiety and brain volume after hearing loss and tinnitus: cohort study in the UK Biobank

Auteurs: Xiaowan Chen, Kejia Hu, Huan Song, Li Yin, Magnus Kaijser, Tiril P. Gurholt, Ole A. Andreassen, Unnur Valdimarsdóttir, Fang Fang, Maoli Duan
Publié dans: BJPsych Open, Numéro 10, 2024, ISSN 2056-4724
Éditeur: Cambridge university Press
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Adipose tissue distribution from body MRI is associated with cross-sectional and longitudinal brain age in adults

Auteurs: Dani Beck, Ann-Marie G de Lange, Dag Alnæs, Ivan I Maximov, Mads L Pedersen, Olof Dahlqvist Leinhard, Jennifer Linge, Rozalyn Simon, Geneviève Richard, Kristine M Ulrichsen, Erlend S Dørum, Knut K Kolskår, Anne-Marthe Sanders, Adriano Winterton, Tiril P Gurholt, Tobias Kaufmann, Nils Eiel Steen, Jan Egil Nordvik, Ole A Andreassen, Lars T Westlye
Publié dans: NeuroImage: Clinical, 2022, ISSN 2213-1582
Éditeur: Elsevier BV
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Cardiometabolic risk factors associated with brain age and accelerated brain ageing

Auteurs: Dani Beck, Ann‐Marie G. de Lange, Mads L. Pedersen, Dag Alnæs, Ivan I. Maximov, Irene Voldsbekk, Geneviève Richard, Anne‐Marthe Sanders, Kristine M. Ulrichsen, Erlend S. Dørum, Knut K. Kolskår, Einar A. Høgestøl, Nils Eiel Steen, Srdjan Djurovic, Ole A. Andreassen, Jan E. Nordvik, Tobias Kaufmann, Lars T. Westlye
Publié dans: Human Brain Mapping, Numéro 43, 2023, Page(s) 700-720, ISSN 1065-9471
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Views on sharing mental health data for research purposes: qualitative analysis of interviews with people with mental illness

Auteurs: Emily Watson, Sue Fletcher-Watson, Elizabeth Joy Kirkham
Publié dans: BMC Medical Ethics, Numéro 24, 2023, ISSN 1472-6939
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Trans-ancestry genome-wide study of depression identifies 697 associations implicating cell types and pharmacotherapies

Auteurs: Mark J. Adams, Fabian Streit, Xiangrui Meng, Swapnil Awasthi, Brett N. Adey, Karmel W. Choi, V. Kartik Chundru, Jonathan R.I. Coleman, Bart Ferwerda, Jerome C. Foo, Zachary F. Gerring, Olga Giannakopoulou, Priya Gupta, Alisha S.M. Hall, Arvid Harder, David M. Howard, Christopher Hübel, Alex S.F. Kwong, Daniel F. Levey, Brittany L. Mitchell, Guiyan Ni, Vanessa K. Ota, Oliver Pain, Gita A. Pathak,
Publié dans: Cell, Numéro 188, 2025, Page(s) 640-652.e9, ISSN 0092-8674
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The oxytocin signalling gene pathway contributes to the association between loneliness and cardiometabolic health

Auteurs: Adriano Winterton, Francesco Bettella, Dani Beck, Tiril P. Gurholt, Nils Eiel Steen, Linn Rødevand, Lars T. Westlye, Ole A. Andreassen, Daniel S. Quintana
Publié dans: Psychoneuroendocrinology, 2022, ISSN 0306-4530
Éditeur: Pergamon Press
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Genomics yields biological and phenotypic insights into bipolar disorder

Auteurs: Kevin S. O’Connell, Maria Koromina, Tracey van der Veen, Toni Boltz, Friederike S. David, Jessica Mei Kay Yang, Keng-Han Lin, Xin Wang, Jonathan R. I. Coleman, Brittany L. Mitchell, Caroline C. McGrouther, Aaditya V. Rangan, Penelope A. Lind, Elise Koch, Arvid Harder, Nadine Parker, Jaroslav Bendl, Kristina Adorjan, Esben Agerbo, Diego Albani, Silvia Alemany, Ney Alliey-Rodriguez, Thomas D. Als,
Publié dans: Nature, 2025, ISSN 0028-0836
Éditeur: Nature Publishing Group
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The Effect of School Bullying on Pupils' Perceived Stress and Wellbeing During the Covid-19 Pandemic:A Longitudinal Study

Auteurs: Elizabeth J. Kirkham; C. F. Huggins; Fawns-Ritchie C
Publié dans: Journal of Child & Adolescent Trauma , pp. 1-8 . https://doi.org/10.1007/s40653-022-00509-7, Numéro 18, 2022, ISSN 0028-0836
Éditeur: Nature Publishing Group
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Association of stress-related disorders with subsequent risk of all-cause and cause-specific mortality: A population-based and sibling-controlled cohort study

Auteurs: Fan Tian, Qing Shen, Yihan Hu, Weimin Ye, Unnur A. Valdimarsdóttir, Huan Song, Fang Fang
Publié dans: The Lancet Regional Health - Europe, Numéro 18, 2022, ISSN 2666-7762
Éditeur: Elsevier
DOI: 10.1016/j.lanepe.2022.100402

A family study of symbolic learning and synaptic plasticity in autism spectrum disorder

Auteurs: Granerud G, Elvsåshagen T, Arntzen E, Juhasz K, Emilsen NM, Sønderby IE, Nærland T, Malt EA
Publié dans: Frontiers in Human Neuroscience, 2022, ISSN 1662-5161
Éditeur: Frontiers Research Foundation
DOI: 10.3389/fnhum.2022.950922

Replicating extensive brain structural heterogeneity in individuals with schizophrenia and bipolar disorder

Auteurs: Thomas Wolfers; Thomas Wolfers; Thomas Wolfers; Jaroslav Rokicki; Jaroslav Rokicki; Dag Alnæs; Dag Alnæs; Pierre Berthet; Pierre Berthet; Ingrid Agartz; Seyed Mostafa Kia; Tobias Kaufmann; Mariam Zabihi; Torgeir Moberget; Torgeir Moberget; Ingrid Melle; Christian F. Beckmann; Ole A. Andreassen; Ole A. Andreassen; Andre F. Marquand; Andre F. Marquand; Lars T. Westlye; Lars T. Westlye
Publié dans: Human Brain Mapping, Numéro 25, 2021, ISSN 1065-9471
Éditeur: John Wiley & Sons Inc.
DOI: 10.1002/hbm.25386

Extensive brain structural heterogeneity in individuals with schizophrenia and bipolar disorder

Auteurs: Wolfers, Thomas; Rokicki, Jaroslav; Alnaes, Dag; Agartz, Ingrid; Kia, Seyed Mostafa; Kaufmann, Tobias; Zabihi, Mariam; Moberget, Torgeir; Melle, Ingrid; Beckmann, Christian F; Andreassen, Ole A; Marquand, Andre F; Westlye, Lars T
Publié dans: HBM, Numéro 23, 2021, ISSN 1065-9471
Éditeur: John Wiley & Sons Inc.
DOI: 10.1101/2020.05.08.20095091

1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans

Auteurs: Ida E. Sønderby, Dennis van der Meer, Clara Moreau, Tobias Kaufmann, G. Bragi Walters, Maria Ellegaard, Abdel Abdellaoui, David Ames, Katrin Amunts, Micael Andersson, Nicola J. Armstrong, Manon Bernard, Nicholas B. Blackburn, John Blangero, Dorret I. Boomsma, Henry Brodaty, Rachel M. Brouwer, Robin Bülow, Rune Bøen, Wiepke Cahn, Vince D. Calhoun, Svenja Caspers, Christopher R. K. Ching, Sven Ci
Publié dans: Translational Psychiatry, Numéro 11/1, 2021, ISSN 2158-3188
Éditeur: Nature Publishing Group
DOI: 10.1038/s41398-021-01213-0

Adverse muscle composition predicts all-cause mortality in the UK Biobank imaging study.

Auteurs: Jennifer Linge; Mikael Petersson; Mikael Forsgren; Arun J. Sanyal; Olof Dahlqvist Leinhard
Publié dans: Journal of Cachexia, Sarcopenia and Muscle, Vol 12, Iss 6, Pp 1513-1526 (2021), Numéro 16, 2021, ISSN 2190-5991
Éditeur: Springer Verlag
DOI: 10.1002/jcsm.12834

Bio-psycho-social factors’ associations with brain age: a large-scale UK Biobank diffusion study of 35,749 participants

Auteurs: Max Korbmacher, Tiril P. Gurholt, Ann-Marie G. de Lange, Dennis van der Meer, Dani Beck, Eli Eikefjord, Arvid Lundervold, Ole A. Andreassen, Lars T. Westlye, Ivan I. Maximov
Publié dans: Frontiers in Psychology, Numéro 14, 2023, ISSN 1664-1078
Éditeur: Frontiers Research Foundation
DOI: 10.3389/fpsyg.2023.1117732

Psychiatric disorders and subsequent risk of cardiovascular disease: a longitudinal matched cohort study across three countries

Auteurs: Qing Shen, Dorte Helenius Mikkelsen, Laura Birgit Luitva, Huan Song, Silva Kasela, Thor Aspelund, Jacob Bergstedt, Yi Lu, Patrick F. Sullivan, Weimin Ye, Katja Fall, Per Tornvall, Yudi Pawitan, Ole A. Andreassen, Alfonso Buil, Lili Milani, Fang Fang, Unnur Valdimarsdóttir
Publié dans: eClinicalMedicine, Numéro 61, 2023, Page(s) 102063, ISSN 2589-5370
Éditeur: The Lancet
DOI: 10.1016/j.eclinm.2023.102063

Shared genetic loci between depression and cardiometabolic traits

Auteurs: Kristin Torgersen, Zillur Rahman, Shahram Bahrami, Guy Frederick Lanyon Hindley, Nadine Parker, Oleksandr Frei, Alexey Shadrin, Kevin S. O’Connell, Martin Tesli, Olav B. Smeland, John Munkhaugen, Srdjan Djurovic, Toril Dammen, Ole A. Andreassen
Publié dans: PLOS Genetics, Numéro 18, 2022, Page(s) e1010161, ISSN 1553-7404
Éditeur: Open Access publisher
DOI: 10.1371/journal.pgen.1010161

Shared genetic architecture between mental health and the brain functional connectome in the UK Biobank

Auteurs: Daniel Roelfs, Oleksandr Frei, Dennis van der Meer, Elleke Tissink, Alexey Shadrin, Dag Alnaes, Ole A. Andreassen, Lars T. Westlye, Tobias Kaufmann
Publié dans: BMC Psychiatry, Numéro 23, 2023, ISSN 1471-244X
Éditeur: BioMed Central
DOI: 10.1186/s12888-023-04905-7

Incidence Trajectories of Psychiatric Disorders After Assault, Injury, and Bereavement

Auteurs: Yufeng Chen, Qing Shen, Paul Lichtenstein, Jaimie L. Gradus, Filip K. Arnberg, Henrik Larsson, Brian M. D’Onofrio, Fang Fang, Huan Song, Unnur A. Valdimarsdottir
Publié dans: JAMA Psychiatry, Numéro 81, 2024, Page(s) 374, ISSN 2168-622X
Éditeur: American Medical Association
DOI: 10.1001/jamapsychiatry.2023.5156

Genetic Association Between Schizophrenia and Cortical Brain Surface Area and Thickness

Auteurs: Weiqiu Cheng, Oleksandr Frei, Dennis van der Meer, Yunpeng Wang, Kevin S. O’Connell, Yunhan Chu, Shahram Bahrami, Alexey A. Shadrin, Dag Alnæs, Guy F. L. Hindley, Aihua Lin, Naz Karadag, Chun-Chieh Fan, Lars T. Westlye, Tobias Kaufmann, Espen Molden, Anders M. Dale, Srdjan Djurovic, Olav B. Smeland, Ole A. Andreassen
Publié dans: JAMA Psychiatry, Numéro 78, 2021, Page(s) 1020, ISSN 2168-622X
Éditeur: American Medical Association
DOI: 10.1001/jamapsychiatry.2021.1435

COGEDAP: A COmprehensive GEnomic Data Analysis Platform

Auteurs: Bayram Cevdet Akdeniz, Oleksandr Frei, Espen Hagen, Tahir Tekin Filiz, Sandeep Karthikeyan, Joelle Pasman, Andreas Jangmo, Jacob Bergsted, John R. Shorter, Richard Zetterberg, Joeri Meijsen, Ida Elken Sonderby, Alfonso Buil, Martin Tesli, Yi Lu, Patrick Sullivan, Ole Andreassen, Eivind Hovig
Publié dans: Arxiv, 2022
Éditeur: Cornell University
DOI: 10.48550/arxiv.2212.14103

Pleiotropic and sex-specific genetic architecture of circulating metabolic markers

Auteurs: Dennis van der Meer, Zillur Rahman, Aigar Ottas, Pravesh Parekh, Gleda Kutrolli, Sara Stinson, Maria Koromina, Jaroslav Rokicki, Ida Sonderby, Nadine Parker, Markos Tesfaye, Guy Hindley, Linn Rodevand, Elise Koch, Nils Steen, Jens Berg, Kevin O'Connell, Olav Smeland, Oleksandr Frei, Anders Dale, Srdjan Djurovic, Kelli Lehto, Maris Alver, Lili Milani, Alexey Shadrin, Ole Andreassen
Publié dans: 2024, ISSN 2692-8205
Éditeur: Cold Spring Harbor Laboratory
DOI: 10.1101/2024.07.30.24311254

Efficient meta-analysis of multivariate genome-wide association studies with Meta-MOSTest

Auteurs: Aihua Lin, Alexey Shadrin, Dennis van der Meer, Guy Hindley, Weiqiu Cheng, Ida Elken Sønderby, Shahram Bahrami, Kevin S O’Connell, Zillur Rahman, Nadine Parker, Olav B Smeland, Chun C. Fan, Dominic Holland, Anders M Dale, Ole A Andreassen, Oleksandr Frei
Publié dans: 2022
Éditeur: Cold Spring Harbor Laboratory
DOI: 10.1101/2022.08.18.504383

The Norwegian Mother, Father, and Child cohort study (MoBa) genotyping data resource: MoBaPsychGen pipeline v.1

Auteurs: Elizabeth C. Corfield, Oleksandr Frei, Alexey A. Shadrin, Zillur Rahman, Aihua Lin, Lavinia Athanasiu, Bayram Cevdet Akdeniz, Laurie Hannigan, Robyn E. Wootton, Chloe Austerberry, Amanda Hughes, Martin Tesli, Lars T. Westlye, Hreinn Stefánsson, Kári Stefánsson, Pål R. Njølstad, Per Magnus, Neil M. Davies, Vivek Appadurai, Gibran Hemani, Eivind Hovig, Tetyana Zayats, Helga Ask, Ted Reichbo
Publié dans: bioRxiv, 2022
Éditeur: Cold Spring Harbor Laboratory
DOI: 10.1101/2022.06.23.496289

Finemap-MiXeR: A variational Bayesian approach for genetic finemapping

Auteurs: Bayram Cevdet Akdeniz, Oleksandr Frei, Alexey Shadrin, Dmitry Vetrov, Dmitry Kropotov, Eivind Hovig, Ole A. Andreassen, Anders M. Dale
Publié dans: Biorxiv, 2023
Éditeur: Cold Spring Harbor Laboratory
DOI: 10.1101/2022.11.30.518509

Acute COVID-19 severity and mental health morbidity trajectories in patient populations of six nations: an observational study

Auteurs: Magnúsdóttir et al
Publié dans: The Lancet Public Health, 2022, ISSN 2468-2667
Éditeur: [Oxford] : Elsevier, Ltd., [2016]-
DOI: 10.1016/s2468-2667(22)00042-1

Better treatment response in people with obsessive-compulsive disorder is associated with more use of a planning-focused coping style

Auteurs: Elizabeth Kirkham, Yintao Cao, Martyna Król
Publié dans: Open Research Europe, Numéro 4, 2024, Page(s) 57, ISSN 2732-5121
Éditeur: https://open-research-europe.ec.europa.eu/articles/4-57
DOI: 10.12688/openreseurope.17056.1

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