Predicting comorbid cardiovascular disease in individuals with mental disorder by decoding disease mechanisms

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Quality Management Plan
Genotyped (chipped) and long range phased Nordic citizens

Genotyped chippeed and long range phased more than one million Nordic citizens M18

Report on dissemination towards industry
Identify interplay between rare and common variants associated with CVD comorbidity in mental illness
Identified rare gene risk variants associated with mental disorders and comorbid CVD
Innovation Management Plan
Report overlap of CVD-mental illness risk genes with body fatty tissue age
Protocols for distributed data analyses

Protocols for distributed data analyses in compliance with ethical, privacy, and GDPR regulations, with scalable technology.

Define non-inherited factors of lifestyle and behaviour
Genes, common/rare variants and pathways/networks associated with CVD-related side effects of antipsychotics/SSRIs

Genes, common/rare variants and pathways/networks associated with CVD-related side effects of antipsychotics/SSRIs.This is a combination of the two deliverables from the original proposal:D5.3 Genes and common/rare variants associated with CVD-related side effects of antipsychotics/SSRIsD5.4 Pathways/networks associated with CVD-related side effects of antipsychotics/SSRIsSince they were similar in scope they were merged in agreement with the Project Officer.

Analysis of a) medication influence and genetic influenc

Analysis of a) medication influence on CVD trajectories for mental disorder patients and b) genetic influence on trajectories in mental disorders and CVD

Report on scientific outreach activities and public outreach activities - M12

Report on scientific outreach activities and public outreach activities. Including information on CoMorMent 6-monthly newsletters.

Validation of stratification tools in re-phenotyped samples

Validation of stratification tools in re-phenotyped samples. A brief description of the achievement.

Report on scientific outreach activities and public outreach activities - M24

Report on scientific outreach activities and public outreach activitiesIncluding information on CoMorMent 6monthly newsletters

Report pharmaceutical targets
IP/Knowledge Management Plan
Dissemination, Exploitation and Communication Plan

Dissemination, Exploitation and Communication Plan and yearly updates. Including a description of CoMorMent website and Social Media channels operational.

Report overlap of CVD-mental illness risk genes with brain age and its genetic architecture

Report overlap of CVDmental illness risk genes with brain age and its genetic architecture

Report of functional mechanisms

A comprehensive report of functional mechanisms

Risk Management Plan
CoMorMent Coordination team established
Analysis of downstream trajectories

Analysis of downstream trajectories in individuals first diagnosed with a mental disorders or b CVD

Report on scientific outreach activities and public outreach activities - M48

Report on scientific outreach activities and public outreach activities - M24.Including information on CoMorMent 6-monthly newsletters.

Definition and harmonization of phenotypic and trajectories data from registries

Infrastructure for coordinated analysis of individual genotypes and phenotypes

Infrastructure for coordinated analysis of individual genotypes and phenotypes from more than one million participants

Analytical tools for imputation and large-scale genotype-phenotype analysis

State-of-the-art analytical tools for imputation and large-scale genotype-phenotype analysis

Data platform for distributed data analysis

A secure data platform for distributed data analysis, including secure computing clusters for each country.

Presentations from the workshop directed at clinical researchers
CoMorMent website and Social Media channels

The CoMorMent website is the key hub for providing detailed dissemination and communication material. The site will feature e.g. abstracts and lay summaries of scientific papers, newsletters, links to articles in popular science publications, and other material as outlined in Sections 2.2.1 and 2.2.5. CoMorMent will exploit social media for both dissemination and communication (Twitter, LinkedIn, Facebook, YouTube) purposes and to direct traffic to the project website. This task entails establishing the project website, Twitter, LinkedIn, Facebook accounts and a YouTube channel. All partners will provide material to be published. The partners will author a lay summary of the partner’s scientific articles for posting on the project website.

Data Management Plan

Tools and code openly available

Make tools and code openly available, incl. documentation for reproducibility

Annual Project Meeting - Y2

Meeting at DECODE Agenda+minutes

Final Project Meeting

Organized by UiO, in BrusselsAgenda + minutes

Annual Project Meeting - Y4

Meeting organized at REGHAgenda+minutes

Annual Project Meeting - Y3

Meeting at UTartuAgenda+minutes

Publications

Cardiovascular-related deaths at the beginning of the COVID-19 outbreak: a prospective analysis based on the UK Biobank

Author(s): Wang J, Zhu J, Yang H, Hu Y, Sun Y, Ying Z, Qu Y, Valdimarsdottir U, Fang F, Song H.
Published in: BMJ open, Issue 114;5, 2021, ISSN 2044-6055
Publisher: BMJ Publishing Group
DOI: 10.1136/bmjopen-2020-046931

Mental illness and COVID-19 vaccination: a multinational investigation of observational & register-based data

Author(s): Mary M. Barker, Kadri Kõiv, Ingibjörg Magnúsdóttir, Hannah Milbourn, Bin Wang, Xinkai Du, Gillian Murphy, Eva Herweijer, Elísabet U. Gísladóttir, Huiqi Li, Anikó Lovik, Anna K. Kähler, Archie Campbell, Maria Feychting, Arna Hauksdóttir, Emily E. Joyce, Edda Bjork Thordardottir, Emma M. Frans, Asle Hoffart, Reedik Mägi, Gunnar Tómasson, Kristjana Ásbjörnsdóttir, Jóhanna Jakobsdótti
Published in: Nature Communications, Issue 15, 2024, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-024-52342-1

Characterising the shared genetic determinants of bipolar disorder, schizophrenia and risk-taking.

Author(s): Guy Hindley; Guy Hindley; Shahram Bahrami; Nils Eiel Steen; Kevin S. O’Connell; Oleksandr Frei; Oleksandr Frei; Alexey A. Shadrin; Francesco Bettella; Linn Rødevand; Chun Chieh Fan; Chun Chieh Fan; Anders M. Dale; Srdjan Djurovic; Srdjan Djurovic; Olav B. Smeland; Ole A. Andreassen
Published in: Translational Psychiatry, Vol 11, Iss 1, Pp 1-10 (2021), Issue 20, 2021, ISSN 2158-3188
Publisher: Nature Publishing Group
DOI: 10.1038/s41398-021-01576-4

Deficit of homozygosity among 1.52 million individuals and genetic causes of recessive lethality

Author(s): Asmundur Oddsson, Patrick Sulem, Gardar Sveinbjornsson, Gudny A. Arnadottir, Valgerdur Steinthorsdottir, Gisli H. Halldorsson, Bjarni A. Atlason, Gudjon R. Oskarsson, Hannes Helgason, Henriette Svarre Nielsen, David Westergaard, Juha M. Karjalainen, Hildigunnur Katrinardottir, Run Fridriksdottir, Brynjar O. Jensson, Vinicius Tragante, Egil Ferkingstad, Hakon Jonsson, Sigurjon A. Gudjonsson, Doruk
Published in: Nature Communications, Issue 14, 2023, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-023-38951-2

Disease trajectories and mortality among individuals diagnosed with depression: a community-based cohort study in UK Biobank

Author(s): Xin Han, Can Hou, Huazhen Yang, Wenwen Chen, Zhiye Ying, Yao Hu, Yajing Sun, Yuanyuan Qu, Lei Yang, Unnur A. Valdimarsdóttir, Wei Zhang, Haomin Yang, Fang Fang, Huan Song
Published in: Molecular Psychiatry, 2021, ISSN 1359-4184
Publisher: Nature Publishing Group
DOI: 10.1038/s41380-021-01170-6

Thirty novel sequence variants impacting human intracranial volume

Author(s): Muhammad Sulaman Nawaz, Gudmundur Einarsson, Mariana Bustamante, Rosa S Gisladottir, G Bragi Walters, Gudrun A Jonsdottir, Astros Th Skuladottir, Gyda Bjornsdottir, Sigurdur H Magnusson, Bergrun Asbjornsdottir, Unnur Unnsteinsdottir, Engilbert Sigurdsson, Palmi V Jonsson, Vala Kolbrun Palmadottir, Sigurjon A Gudjonsson, Gisli H Halldorsson, Egil Ferkingstad, Ingileif Jonsdottir, Gudmar Thorleifsso
Published in: BRAIN COMMUNICATIONS, Issue Volume 4, Issue 6, 2022, Page(s) 1 to 14, ISSN 2632-1297
Publisher: Oxford academic press
DOI: 10.1093/braincomms/fcac271

Genetic Stratification of Age‐Dependent Parkinson's Disease Risk by Polygenic Hazard Score

Author(s): Lasse Pihlstrøm, Chun C. Fan, Oleksandr Frei, Manuela Tan, Roshan A. Karunamuni, Cornelis Blauwendraat, Sara Bandres‐Ciga, Ziv Gan‐Or, Donald G. Grosset, null null, Anders M. Dale, Tyler M. Seibert, Ole A. Andreassen
Published in: Movement Disorders, Issue 37, 2023, Page(s) 62-69, ISSN 0885-3185
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/mds.28808

Pre-pandemic psychiatric disorders and risk of COVID-19: a UK Biobank cohort analysis

Author(s): Huazhen Yang, Wenwen Chen, Yao Hu, Yilong Chen, Yu Zeng, Yajing Sun, Zhiye Ying, Junhui He, Yuanyuan Qu, Donghao Lu, Fang Fang, Unnur A Valdimarsdóttir, Huan Song
Published in: The Lancet Healthy longevity, Issue 1, 2020, ISSN 2666-7568
Publisher: Elsevier
DOI: 10.1016/s2666-7568(20)30013-1

Greater male than female variability in regional brain structure across the lifespan

Author(s): Lara M. Wierenga; Gaelle E. Doucet; Gaelle E. Doucet; Danai Dima; Danai Dima; Ingrid Agartz; Ingrid Agartz; Moji Aghajani; Moji Aghajani; Theophilus N. Akudjedu; Theophilus N. Akudjedu; Anton Albajes-Eizagirre; Dag Alnæs; Dag Alnæs; Kathryn I. Alpert; Ole A. Andreassen; Ole A. Andreassen; Alan Anticevic; Philip Asherson; Tobias Banaschewski; Núria Bargalló; Sarah Baumeister; Ramona Baur-Streub
Published in: Human Brain Mapping, Issue 31, 2022, Page(s) reponame:r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau, ISSN 1065-9471
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/hbm.25204

Developmental manifestations of polygenic risk for bipolar disorder from infancy to middle childhood

Author(s): Ragna Bugge Askeland, Laurie J. Hannigan, Kevin S. O’Connell, Elizabeth C. Corfield, Oleksandr Frei, Anita Thapar, George Davey Smith, Ted Reichborn-Kjennerud, Ole A. Andreassen, Helga Ask, Alexandra Havdahl
Published in: Translational Psychiatry, Issue 13, 2023, ISSN 2158-3188
Publisher: Nature Publishing Group
DOI: 10.1038/s41398-023-02522-2

Sex‐ and age‐specific associations between cardiometabolic risk and white matter brain age in the UK Biobank cohort

Author(s): Sivaniya Subramaniapillai; Sana Suri; Claudia Barth; Ivan I. Maximov; Irene Voldsbekk; Dennis van der Meer; Tiril P. Gurholt; Dani Beck; Bogdan Draganski; Ole A. Andreassen; Klaus P. Ebmeier; Lars T. Westlye; Ann‐Marie G. de Lange
Published in: HBM, Issue 29, 2022, ISSN 1065-9471
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/hbm.25882

Cohort Profile: COVIDMENT: COVID-19 cohorts on mental health across six nations

Author(s): Anna Bára Unnarsdóttir, Anikó Lovik, Chloe Fawns-Ritchie, Helga Ask, Kadri Kõiv, Kristen Hagen, Maria Didriksen, Lea Arregui Nordahl Christoffersen, Alexander Berg Garðarsson, Andrew McIntosh, Anna K Kähler, Archie Campbell, Arna Hauksdóttir, Christian Erikstrup, Dorte Helenius Mikkelsen, Drew Altschul, Edda Bjork Thordardottir, Emma Maria Frans, Gerd Kvale, Gunnar Tómasson, Hanna Maria Ka
Published in: Intl Jnl Epidemiology, Issue 3, 2021, Page(s) e108–e122, ISSN 1464-3685
Publisher: Oxford University Press
DOI: 10.1093/ije/dyab234

Metabolic Profile and Long-Term Risk of Depression, Anxiety, and Stress-Related Disorders

Author(s): Charilaos Chourpiliadis, Yu Zeng, Anikó Lovik, Dang Wei, Unnur Valdimarsdóttir, Huan Song, Niklas Hammar, Fang Fang
Published in: JAMA Network Open, Issue 7, 2024, Page(s) e244525, ISSN 2574-3805
Publisher: JAMA
DOI: 10.1001/jamanetworkopen.2024.4525

Lessons Learned From Neuroimaging Studies of Copy Number Variants: A Systematic Review.

Author(s): Claudia Modenato; Sandra Martin-Brevet; Clara A. Moreau; Borja Rodriguez-Herreros; Kuldeep Kumar; Bogdan Draganski; Ida E Sønderby; Sébastien Jacquemont
Published in: "Biological Psychiatry, Elsevier, 2021, 90 (9), pp.596-610. ⟨10.1016/j.biopsych.2021.05.028⟩", Issue 4, 2021, ISSN 0006-3223
Publisher: Elsevier BV
DOI: 10.1016/j.biopsych.2021.05.028

Cardiometabolic risk factors associated with brain age and accelerate brain ageing

Author(s): Dani Beck; Dani Beck; Ann-Marie Glasø de Lange; Ann-Marie Glasø de Lange; Ann-Marie Glasø de Lange; Mads Lund Pedersen; Mads Lund Pedersen; Dag Alnæs; Dag Alnæs; Ivan I. Maximov; Ivan I. Maximov; Ivan I. Maximov; Irene Voldsbekk; Irene Voldsbekk; Geneviève Richard; Anne-Marthe Sanders; Anne-Marthe Sanders; Kristine Moe Ulrichsen; Kristine Moe Ulrichsen; Erlend S. Dørum; Erlend S. Dørum; Kn
Published in: HBM, Issue 19, 2021, Page(s) 1-21, ISSN 1065-9471
Publisher: John Wiley & Sons Inc.
DOI: 10.1101/2021.02.25.21252272

Shared genetic architecture between neuroticism, coronary artery disease and cardiovascular risk factors

Author(s): Kristin Torgersen, Shahram Bahrami, Oleksandr Frei, Alexey Shadrin, Kevin S. O’ Connell, Olav B. Smeland, John Munkhaugen, Srdjan Djurovic, Toril Dammen, Ole A. Andreassen
Published in: Translational Psychiatry, Issue 11, 2022, ISSN 2158-3188
Publisher: Nature Publishing Group
DOI: 10.1038/s41398-021-01466-9

Distinct biological signature and modifiable risk factors underlie the comorbidity between major depressive disorder and cardiovascular disease

Author(s): Jacob Bergstedt, Joëlle A. Pasman, Ziyan Ma, Arvid Harder, Shuyang Yao, Nadine Parker, Jorien L. Treur, Dirk J. A. Smit, Oleksandr Frei, Alexey A. Shadrin, Joeri J. Meijsen, Qing Shen, Sara Hägg, Per Tornvall, Alfonso Buil, Thomas Werge, Jens Hjerling-Leffler, Thomas D. Als, Anders D. Børglum, Cathryn M. Lewis, Andrew M. McIntosh, Unnur A. Valdimarsdóttir, Ole A. Andreassen, Patrick F. Sulliva
Published in: Nature Cardiovascular Research, Issue 3, 2024, Page(s) 754-769, ISSN 2731-0590
Publisher: Springer Nature
DOI: 10.1038/s44161-024-00488-y

Associations between abdominal adipose tissue, reproductive span, and brain characteristics in post-menopausal women

Author(s): Louise S. Schindler, Sivaniya Subramaniapillai, Claudia Barth, Dennis van der Meer, Mads L. Pedersen, Tobias Kaufmann, Ivan I. Maximov, Jennifer Linge, Olof Dahlqvist Leinhard, Dani Beck, Tiril P. Gurholt, Irene Voldsbekk, Sana Suri, Klaus P. Ebmeier, Bogdan Draganski, Ole A. Andreassen, Lars T. Westlye, Ann-Marie G. de Lange
Published in: NeuroImage: clinical, 2022, ISSN 2213-1582
Publisher: Elsevier BV
DOI: 10.1016/j.nicl.2022.103239

Phenotypically independent profiles relevant to mental health are genetically correlated

Author(s): Daniel Roelfs, Dag Alnæs, Oleksandr Frei, Dennis van der Meer, Olav B. Smeland, Ole A. Andreassen, Lars T. Westlye, Tobias Kaufmann
Published in: Translational Psychiatry, Issue 11/1, 2021, ISSN 2158-3188
Publisher: Nature Publishing Group
DOI: 10.1038/s41398-021-01313-x

COSGAP: COntainerized Statistical Genetics Analysis Pipelines

Author(s): Bayram Cevdet Akdeniz, Oleksandr Frei, Espen Hagen, Tahir Tekin Filiz, Sandeep Karthikeyan, Joëlle Pasman, Andreas Jangmo, Jacob Bergstedt, John R Shorter, Richard Zetterberg, Joeri Meijsen, Ida Elken Sønderby, Alfonso Buil, Martin Tesli, Yi Lu, Patrick Sullivan, Ole A Andreassen, Eivind Hovig
Published in: Bioinformatics Advances, Issue 4, 2024, ISSN 2635-0041
Publisher: Oxford Academic
DOI: 10.1093/bioadv/vbae067

Poor muscle health and cardiometabolic risks associated with antidepressant treatment

Author(s): Patrik Andersson, Jennifer Linge, Tiril P. Gurholt, Ida E. Sønderby, Guy Hindley, Ole A. Andreassen, Olof Dahlqvist Leinhard
Published in: Obesity, Issue 32, 2024, Page(s) 1857-1869, ISSN 1930-7381
Publisher: Wiley-Blackwell
DOI: 10.1002/oby.24085

Patient satisfaction with mental and physical health services: Findings from a UK-wide online survey

Author(s): Elizabeth J. Kirkham; Sue Fletcher-Watson; Iona Beange; Stella W.Y. Chan; Stephen M. Lawrie
Published in: Wellcome Open Research, Issue 14, 2022, ISSN 1936-1521
Publisher: Taylor & Francis
DOI: 10.12688/wellcomeopenres.17973.1

Genetic predisposition and antipsychotic treatment effect on metabolic syndrome in schizophrenia: a ten-year follow-up study using the Estonian Biobank

Author(s): Maris Alver, Silva Kasela, Liina Haring, Laura Birgit Luitva, Krista Fischer, Märt Möls, Lili Milani
Published in: The Lancet Regional Health - Europe, Issue 41, 2024, Page(s) 100914, ISSN 2666-7762
Publisher: Elsevier
DOI: 10.1016/j.lanepe.2024.100914

Familial factors, diet, and risk of cardiovascular disease: a cohort analysis of the UK Biobank

Author(s): Hanyue Zhang, Yu Zeng, Huazhen Yang, Yihan Hu, Yao Hu, Wenwen Chen, Zhiye Ying, Yajing Sun, Yuanyuan Qu, Qian Li, Unnur A Valdimarsdóttir, Huan Song,
Published in: The American Journal of Clinical Nutrition, Issue 114;5, 2021, Page(s) 1837-1846, ISSN 0002-9165
Publisher: American Society for Clinical Nutrition, Inc.
DOI: 10.1093/ajcn/nqab261

No signs of neurodegenerative effects in 15q11.2 BP1-BP2 copy number variant carriers in the UK Biobank

Author(s): Rune Boen, Tobias Kaufmann, Oleksandr Frei, Dennis van der Meer, Srdjan Djurovic, Ole A. Andreassen, Kaja K. Selmer, Dag Alnæs, Ida E. Sønderby
Published in: Translational Psychiatry, Issue 13, 2023, ISSN 2158-3188
Publisher: Nature Publishing Group
DOI: 10.1038/s41398-023-02358-w

Genetic liability for schizophrenia and childhood psychopathology in the general population

Author(s): Laurie J. Hannigan; Ragna Bugge Askeland; Helga Ask; Martin Tesli; Martin Tesli; Elizabeth Corfield; Ziada Ayorech; Øyvind Helgeland; Øyvind Helgeland; Per Magnus; Per Magnus; Pål R. Njølstad; Pål R. Njølstad; Anne-Siri Øyen; Camilla Stoltenberg; Camilla Stoltenberg; Ole A. Andreassen; Ole A. Andreassen; George Davey Smith; Ted Reichborn-Kjennerud; Ted Reichborn-Kjennerud; Alexandra Havdahl
Published in: Schizophrenia Bulletin, Issue 26, 2021, ISSN 0586-7614
Publisher: Oxford University Press
DOI: 10.1093/schbul/sbaa193

The genetic architecture of the human thalamus and its overlap with ten common brain disorders

Author(s): Torbjørn Elvsåshagen, Alexey Shadrin, Oleksandr Frei, Dennis van der Meer, Shahram Bahrami, Vinod Jangir Kumar, Olav Smeland, Lars T. Westlye, Ole A. Andreassen, Tobias Kaufmann
Published in: Nature Communications, Issue 12, 2024, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-23175-z

A comprehensive map of genetic relationships among diagnostic categories based on 48.6 million relative pairs from the Danish genealogy

Author(s): Georgios Athanasiadis, Joeri J Meijsen, Dorte Helenius, Andrew J Schork, Andrés Ingason, Wesley K Thompson, Daniel H Geschwind, Thomas Werge, Alfonso Buil
Published in: PNAS, Issue 119, 2022, ISSN 1091-6490
Publisher: US national academy of sciences
DOI: 10.1073/pnas.2118688119

Finemap-MiXeR: A variational Bayesian approach for genetic finemapping

Author(s): Bayram Cevdet Akdeniz, Oleksandr Frei, Alexey Shadrin, Dmitry Vetrov, Dmitry Kropotov, Eivind Hovig, Ole A. Andreassen, Anders M. Dale
Published in: PLOS Genetics, Issue 20, 2024, Page(s) e1011372, ISSN 1553-7404
Publisher: Public Library of Science
DOI: 10.1371/journal.pgen.1011372

Psychometric Properties and Diagnostic Associations of the Short-Form Community Assessment of Psychic Experiences in a Population-Based Sample of 29 021 Adult Men

Author(s): Viktoria Birkenæs, Nora Refsum Bakken, Evgeniia Frei, Piotr Jaholkowski, Olav B Smeland, Markos Tesfaye, Ingrid Agartz, Ezra Susser, Michaeline Bresnahan, Espen Røysamb, Kjetil Nordbø Jørgensen, Ragnar Nesvåg, Alexandra Havdahl, Ole A Andreassen, Ida Elken Sønderby
Published in: Schizophrenia Bulletin, Issue 49, 2023, Page(s) 1229-1238, ISSN 0586-7614
Publisher: Oxford University Press
DOI: 10.1093/schbul/sbad074

Mental health indicators in Sweden over a 12-month period during the COVID-19 pandemic – Baseline data of the Omtanke2020 Study

Author(s): Anikó Lovik; Juan González-Hijón; Anna K. Kähler; Unnur A. Valdimarsdóttir; Emma M. Frans; Patrik K.E. Magnusson; Nancy L. Pedersen; Per Hall; Kamila Czene; Patrick F. Sullivan; Fang Fang
Published in: Journal of Affective Disorders, Issue 10, 2023, ISSN 0165-0327
Publisher: Elsevier BV
DOI: 10.1016/j.jad.2022.11.004

Plasma Levels of the Cytokines B Cell-Activating Factor (BAFF) and A Proliferation-Inducing Ligand (APRIL) in Schizophrenia, Bipolar, and Major Depressive Disorder: A Cross Sectional, Multisite Study.

Author(s): John Abel Engh; Thor Ueland; Thor Ueland; Thor Ueland; Ingrid Agartz; Ingrid Agartz; Dimitrios Andreou; Dimitrios Andreou; Pål Aukrust; Pål Aukrust; Birgitte Boye; Birgitte Boye; Erlend Bøen; Ole Kristian Drange; Torbjørn Elvsåshagen; Sigrun Hope; Margrethe Collier Høegh; Inge Joa; Inge Joa; Erik Johnsen; Erik Johnsen; Rune A. Kroken; Rune A. Kroken; Trine Vik Lagerberg; Tove Lekva; Ulrik Fr
Published in: 10, Issue 1, 2022, ISSN 0586-7614
Publisher: Oxford University Press
DOI: 10.1093/schbul/sbab106

Metabolomic Investigation of Major Depressive Disorder Identifies a Potentially Causal Association With Polyunsaturated Fatty Acids

Author(s): Eleanor Davyson, Xueyi Shen, Danni A. Gadd, Elena Bernabeu, Robert F. Hillary, Daniel L. McCartney, Mark Adams, Riccardo Marioni, Andrew M. McIntosh
Published in: Biological Psychiatry, Issue 94, 2024, Page(s) 630-639, ISSN 0006-3223
Publisher: Elsevier BV
DOI: 10.1016/j.biopsych.2023.01.027

Linking sarcopenia, brain structure and cognitive performance: a large-scale UK Biobank study

Author(s): Tiril P Gurholt, Miguel Germán Borda, Nadine Parker, Vera Fominykh, Rikka Kjelkenes, Jennifer Linge, Dennis van der Meer, Ida E Sønderby, Gustavo Duque, Lars T Westlye, Dag Aarsland, Ole A Andreassen
Published in: Brain Communications, Issue 6, 2024, ISSN 2632-1297
Publisher: Oxford Academic
DOI: 10.1093/braincomms/fcae083

Additional file 1 of Genetic predispositions to psychiatric disorders and the risk of COVID-19

Author(s): Chen, Wenwen; Zeng, Yu; Suo, Chen; Yang, Huazhen; Chen, Yilong; Hou, Can; Hu, Yao; Ying, Zhiye; Sun, Yajing; Qu, Yuanyuan; Lu, Donghao; Fang, Fang; Valdimarsdóttir, Unnur A.; Song, Huan
Published in: BMC Medicine, Issue 6, 2022, ISSN 1741-7015
Publisher: BioMed Central
DOI: 10.6084/m9.figshare.20579734.v1

How important are parents in the development of child anxiety and depression? A genomic analysis of parent-offspring trios in the Norwegian Mother Father and Child Cohort Study (MoBa)

Author(s): Rosa Cheesman; Espen Moen Eilertsen; Yasmin I. Ahmadzadeh; Line C. Gjerde; Line C. Gjerde; Laurie J. Hannigan; Alexandra Havdahl; Alexander I. Young; Alexander I. Young; Thalia C. Eley; Pål R. Njølstad; Pål R. Njølstad; Per Magnus; Ole A. Andreassen; Ole A. Andreassen; Eivind Ystrom; Eivind Ystrom; Tom A. McAdams; Tom A. McAdams
Published in: BMC Medicine, Vol 18, Iss 1, Pp 1-11 (2020), Issue 27, 2020, ISSN 1741-7015
Publisher: BioMed Central
DOI: 10.1101/2020.04.14.20064782

Genetic predispositions to psychiatric disorders and the risk of COVID-19

Author(s): Wenwen Chen; Yu Zeng; Chen Suo; Huazhen Yang; Yilong Chen; Can Hou; Yao Hu; Zhiye Ying; Yajing Sun; Yuanyuan Qu; Donghao Lu; Fang Fang; Unnur A. Valdimarsdóttir; Huan Song
Published in: BMC Medicine, Issue 5, 2022, ISSN 1741-7015
Publisher: BioMed Central
DOI: 10.1186/s12916-022-02520-z

Polygenic risk for schizophrenia and bipolar disorder in relation to cardiovascular biomarkers

Author(s): Elina J. Reponen, Thor Ueland, Jaroslav Rokicki, Francesco Bettella, Monica Aas, Maren C. F. Werner, Ingrid Dieset, Nils E. Steen, Ole A. Andreassen, Martin Tesli
Published in: European Archives of Psychiatry and Clinical Neuroscience, Issue 274, 2024, Page(s) 1223-1230, ISSN 0940-1334
Publisher: Dr. Dietrich Steinkopff Verlag
DOI: 10.1007/s00406-023-01591-0

Considerations on brain age predictions from repeatedly sampled data across time

Author(s): Max Korbmacher, Meng-Yun Wang, Rune Eikeland, Ralph Buchert, Ole A. Andreassen, Thomas Espeseth, Esten Leonardsen, Lars T. Westlye, Ivan I. Maximov, Karsten Specht
Published in: Brain and Behaviour, 2024, ISSN 2162-3279
Publisher: Wiley
DOI: 10.1101/2023.03.31.535038

How important are parents in the development of child anxiety and depression? A genomic analysis of parent-offspring trios in the Norwegian Mother Father and Child Cohort Study (MoBa)

Author(s): Rosa Cheesman, Espen Moen Eilertsen, Yasmin I. Ahmadzadeh, Line C. Gjerde, Laurie J. Hannigan, Alexandra Havdahl, Alexander I. Young, Thalia C. Eley, Pål R. Njølstad, Per Magnus, Ole A. Andreassen, Eivind Ystrom, Tom A. McAdams
Published in: BMC Medicine, Issue 18, 2021, ISSN 1741-7015
Publisher: BioMed Central
DOI: 10.1186/s12916-020-01760-1

Heart rate variability is associated with disease severity in psychosis spectrum disorders.

Author(s): Beatrice R. Benjamin; Mathias Valstad; Torbjørn Elvsåshagen; Erik G. Jönsson; Torgeir Moberget; Adriano Winterton; Marit Haram; Margrethe Collier Høegh; Trine Vik Lagerberg; Nils Eiel Steen; Lars Erik Larsen; Ole A. Andreassen; Lars T. Westlye; Daniel Quintana
Published in: Progress in Neuro-Psychopharmacology and Biological Psychiatry, Issue 17, 2021, ISSN 0278-5846
Publisher: Elsevier BV
DOI: 10.1016/j.pnpbp.2020.110108

Bidirectional genetic overlap between autism spectrum disorder and cognitive traits

Author(s): Sigrun Hope, Alexey A. Shadrin, Aihua Lin, Shahram Bahrami, Linn Rødevand, Oleksandr Frei, Saira J. Hübenette, Weiqiu Cheng, Guy Hindley, Heidi Nag, Line Ulstein, Magdalena Efrim-Budisteanu, Kevin O’Connell, Anders M. Dale, Srdjan Djurovic, Terje Nærland, Ole A. Andreassen
Published in: Translational Psychiatry, Issue 13, 2023, ISSN 2158-3188
Publisher: Nature Publishing Group
DOI: 10.1038/s41398-023-02563-7

Assessing causal links between age at menarche and adolescent mental health: a Mendelian randomisation study

Author(s): Adrian Dahl Askelund, Robyn E. Wootton, Fartein A. Torvik, Rebecca B. Lawn, Helga Ask, Elizabeth C. Corfield, Maria C. Magnus, Ted Reichborn-Kjennerud, Per M. Magnus, Ole A. Andreassen, Camilla Stoltenberg, George Davey Smith, Neil M. Davies, Alexandra Havdahl, Laurie J. Hannigan
Published in: BMC Medicine, Issue 22, 2024, ISSN 1741-7015
Publisher: BioMed Central
DOI: 10.1186/s12916-024-03361-8

Increased circulating IL-18 levels in severe mental disorders indicate systemic inflammasome activation.

Author(s): Attila Szabo; Kevin S O' Connell; Thor Ueland; Thor Ueland; Thor Ueland; Mashhood Ahmed Sheikh; Ingrid Agartz; Ingrid Agartz; Dimitrios Andreou; Dimitrios Andreou; Pål Aukrust; Pål Aukrust; Birgitte Boye; Birgitte Boye; Erlend Bøen; Ole Kristian Drange; Torbjørn Elvsåshagen; Torbjørn Elvsåshagen; John Abel Engh; Sigrun Hope; Margrethe Collier Høegh; Inge Joa; Inge Joa; Erik Johnsen; Erik J
Published in: Brain, behavior, and immunity, Issue 4, 2022, Page(s) 299-306, ISSN 0889-1591
Publisher: Academic Press
DOI: 10.1016/j.bbi.2021.10.017

Polygenic overlap and shared genetic loci between loneliness, severe mental disorders, and cardiovascular disease risk factors suggest shared molecular mechanisms

Author(s): Linn Rødevand, Shahram Bahrami, Oleksandr Frei, Aihua Lin, Osman Gani, Alexey Shadrin, Olav B. Smeland, Kevin S. O’ Connell, Torbjørn Elvsåshagen, Adriano Winterton, Daniel S. Quintana, Guy F. L. Hindley, Maren C. F. Werner, Srdjan Djurovic, Anders M. Dale, Trine V. Lagerberg, Nils Eiel Steen, Ole A. Andreassen
Published in: Translational Psychiatry, Issue 11/1, 2021, ISSN 2158-3188
Publisher: Nature Publishing Group
DOI: 10.1038/s41398-020-01142-4

The link between liver fat and cardiometabolic diseases is highlighted by genome-wide association study of MRI-derived measures of body composition

Author(s): Dennis van der Meer, Tiril P. Gurholt, Ida E. Sønderby, Alexey A. Shadrin, Guy Hindley, Zillur Rahman, Ann-Marie G. de Lange, Oleksandr Frei, Olof D. Leinhard, Jennifer Linge, Rozalyn Simon, Dani Beck, Lars T. Westlye, Sigrun Halvorsen, Anders M. Dale, Tom H. Karlsen, Tobias Kaufmann, Ole A. Andreassen
Published in: Communications Biology, Issue 5, 2022, ISSN 2399-3642
Publisher: Nature portfolio
DOI: 10.1038/s42003-022-04237-4

What we learn about bipolar disorder from large‐scale neuroimaging: Findings and future directions from the <scp>ENIGMA</scp> Bipolar Disorder Working Group

Author(s): Christopher R. K. Ching, Derrek P. Hibar, Tiril P. Gurholt, Abraham Nunes, Sophia I. Thomopoulos, Christoph Abé, Ingrid Agartz, Rachel M. Brouwer, Dara M. Cannon, Sonja M. C. de Zwarte, Lisa T. Eyler, Pauline Favre, Tomas Hajek, Unn K. Haukvik, Josselin Houenou, Mikael Landén, Tristram A. Lett, Colm McDonald, Leila Nabulsi, Yash Patel, Melissa E. Pauling, Tomas Paus, Joaquim Radua, Marcio G. Soe
Published in: Human Brain Mapping, Issue 43, 2023, Page(s) 56-82, ISSN 1065-9471
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/hbm.25098

Genome-by-Trauma Exposure Interactions in Adults With Depression in the UK Biobank

Author(s): Melisa Chuong, Mark J. Adams, Alex S. F. Kwong, Chris S. Haley, Carmen Amador, Andrew M. McIntosh
Published in: JAMA Psychiatry, Issue 79, 2022, Page(s) 1110, ISSN 2168-622X
Publisher: American Medical Association
DOI: 10.1001/jamapsychiatry.2022.2983

Experience of clinical services shapes attitudes to mental health data sharing: findings from a UK-wide survey

Author(s): E. J. Kirkham; S. M. Lawrie; C. J. Crompton; M. H. Iveson; N. D. Jenkins; J. Goerdten; I. Beange; S. W. Y. Chan; A. McIntosh; S. Fletcher-Watson
Published in: BMC public health, 22(1):357, Issue 9, 2022, ISSN 1471-2458
Publisher: BioMed Central
DOI: 10.1186/s12889-022-12694-z

Quantifying the relative importance of genetics and environment on the comorbidity between mental and cardiometabolic disorders using 17 million Scandinavians

Author(s): Joeri Meijsen, Kejia Hu, Morten D. Krebs, Georgios Athanasiadis, Sarah Washbrook, Richard Zetterberg, Raquel Nogueira Avelar e Silva, John R. Shorter, Jesper R. Gådin, Jacob Bergstedt, David M. Howard, Weimin Ye, Yi Lu, Unnur A. Valdimarsdóttir, Andrés Ingason, Dorte Helenius, Oleguer Plana-Ripoll, John J. McGrath, Nadia Micali, Ole A. Andreassen, Thomas M. Werge, Fang Fang, Alfonso Buil
Published in: Nature Communications, Issue 15, 2024, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-024-49507-3

Extensive bidirectional genetic overlap between bipolar disorder and cardiovascular disease phenotypes

Author(s): Linn Rødevand, Shahram Bahrami, Oleksandr Frei, Yunhan Chu, Alexey Shadrin, Kevin S. O’Connell, Olav B. Smeland, Torbjørn Elvsåshagen, Guy F. L. Hindley, Srdjan Djurovic, Anders M. Dale, Trine V. Lagerberg, Nils Eiel Steen, Ole A. Andreassen
Published in: Translational Psychiatry, Issue 11/1, 2021, ISSN 2158-3188
Publisher: Nature Publishing Group
DOI: 10.1038/s41398-021-01527-z

Characterizing the polygenic overlap and shared loci between rheumatoid arthritis and cardiovascular diseases

Author(s): Xiaohui Sun, Yu Qian, Weiqiu Cheng, Ding Ye, Bin Liu, Dan Zhou, Chengping Wen, Ole A. Andreassen, Yingying Mao
Published in: BMC Medicine, Issue 22, 2024, ISSN 1741-7015
Publisher: BioMed Central
DOI: 10.1186/s12916-024-03376-1

Population-based body–brain mapping links brain morphology with anthropometrics and body composition

Author(s): Tiril P. Gurholt, Tobias Kaufmann, Oleksandr Frei, Dag Alnæs, Unn K. Haukvik, Dennis van der Meer, Torgeir Moberget, Kevin S. O’Connell, Olof D. Leinhard, Jennifer Linge, Rozalyn Simon, Olav B. Smeland, Ida E. Sønderby, Adriano Winterton, Nils Eiel Steen, Lars T. Westlye, Ole A. Andreassen
Published in: Translational Psychiatry, Issue 11/1, 2021, ISSN 2158-3188
Publisher: Nature Publishing Group
DOI: 10.1038/s41398-021-01414-7

Body mass index and childhood symptoms of depression, anxiety, and attention-deficit hyperactivity disorder: A within-family Mendelian randomization study

Author(s): Amanda M Hughes; Eleanor Sanderson; Tim Morris; Ziada Ayorech; Martin Tesli; Helga Ask; Ted Reichborn-Kjennerud; Ole A Andreassen; Per Magnus; Øyvind Helgeland; Stefan Johansson; Pål Njølstad; George Davey Smith; Alexandra Havdahl; Laura D Howe; Neil M Davies
Published in: eLife, Issue 24, 2022, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.74320

The shared genetic basis of mood instability and psychiatric disorders: A cross-trait genome-wide association analysis

Author(s): Guy Hindley; Kevin S. O'Connell; Zillur Rahman; Oleksandr Frei; Shahram Bahrami; Alexey Shadrin; Margrethe C. Høegh; Weiqiu Cheng; Naz Karadag; Aihua Lin; Linn Rødevand; Chun C. Fan; Srdjan Djurovic; Trine V. Lagerberg; Anders M. Dale; Olav B. Smeland; Ole A. Andreassen
Published in: AMERICAN JOURNAL OF MEDICAL GENETICS, Issue 4, 2022, ISSN 1552-4841
Publisher: Wiley-Liss Inc
DOI: 10.1002/ajmg.b.32907

Cardiovascular disease and subsequent risk of psychiatric disorders: a nationwide sibling-controlled study

Author(s): Qing Shen, Huan Song, Thor Aspelund, Jingru Yu, Donghao Lu, Jóhanna Jakobsdóttir, Jacob Bergstedt, Lu Yi, Patrick Sullivan, Arvid Sjölander, Weimin Ye, Katja Fall, Fang Fang, Unnur Valdimarsdóttir
Published in: eLife, Issue 11, 2022, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.80143

Using a knowledge exchange event to assess study participants’ attitudes to research in a rapidly evolving research context

Author(s): Iona Beange, Elizabeth J. Kirkham, Sue Fletcher-Watson, Matthew H. Iveson, Stephen M. Lawrie, G. David Batty, James P. Boardman, Ian J. Deary, Corri Black, David J. Porteous, Andrew M. McIntosh
Published in: Wellcome Open Research, Issue 5, 2020, Page(s) 24, ISSN 2398-502X
Publisher: Welcome Open Research
DOI: 10.12688/wellcomeopenres.15651.2

Effects of copy number variations on brain structure and risk for psychiatric illness: Large‐scale studies from the ENIGMA working groups on CNVs

Author(s): Ida E. Sønderby, Christopher R. K. Ching, Sophia I. Thomopoulos, Dennis Meer, Daqiang Sun, Julio E. Villalon‐Reina, Ingrid Agartz, Katrin Amunts, Celso Arango, Nicola J. Armstrong, Rosa Ayesa‐Arriola, Geor Bakker, Anne S. Bassett, Dorret I. Boomsma, Robin Bülow, Nancy J. Butcher, Vince D. Calhoun, Svenja Caspers, Eva W. C. Chow, Sven Cichon, Simone Ciufolini, Michael C. Craig, Benedicto Cres
Published in: Human Brain Mapping, 2021, Page(s) online ahead of print, ISSN 1065-9471
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/hbm.25354

Cohort Profile Update: Mental Health Online Survey in the Estonian Biobank (EstBB MHoS)

Author(s): Triinu Ojalo, Elis Haan, Kadri Kõiv, Hanna Maria Kariis, Kristi Krebs, Helen Uusberg, Tuuli Sedman, Urmo Võsa, Mairo Puusepp, Sirje Lind, Innar Hallik, Helene Alavere, null null, Andres Metspalu, Tõnu Esko, Reedik Mägi, Mari Nelis, Georgi Hudjashov, Lili Milani, Kelli Lehto
Published in: International Journal of Epidemiology, Issue 53, 2024, ISSN 0300-5771
Publisher: Oxford University Press
DOI: 10.1093/ije/dyae017

Short-term improvement of mental health after a COVID-19 vaccination

Author(s): Charilaos Chourpiliadis, Anikó Lovik, Anna K. Kähler, Unnur A. Valdimarsdóttir, Emma M. Frans, Fredrik Nyberg, Patrick F. Sullivan, Fang Fang
Published in: PLOS ONE, 2024, ISSN 1932-6203
Publisher: Public Library of Science
DOI: 10.1101/2022.02.22.22271327

Co-development of a Best Practice Checklist for Mental Health Data Science: A Delphi Study

Author(s): Elizabeth J. Kirkham, Catherine J. Crompton, Matthew H. Iveson, Iona Beange, Andrew M. McIntosh, Sue Fletcher-Watson
Published in: Frontiers in Psychiatry, Issue 12, 2021, ISSN 1664-0640
Publisher: Frontiers Research Foundation
DOI: 10.3389/fpsyt.2021.643914

Sex differences in autonomic adverse effects related to antipsychotic treatment and associated hormone profiles

Author(s): Ingrid T. Johansen, Nils Eiel Steen, Linn Rødevand, Synve H. Lunding, Gabriela Hjell, Monica B. E. G. Ormerod, Ingrid Agartz, Ingrid Melle, Trine V. Lagerberg, Mari Nerhus, Ole A. Andreassen
Published in: Schizophrenia, Issue 10, 2024, ISSN 2754-6993
Publisher: Nature publishing
DOI: 10.1038/s41537-023-00430-4

The role of genetic predisposition in cardiovascular risk after cancer diagnosis: a matched cohort study of the UK Biobank

Author(s): Huazhen Yang, Yu Zeng, Wenwen Chen, Yajing Sun, Yao Hu, Zhiye Ying, Junren Wang, Yuanyuan Qu, Fang Fang, Unnur A. Valdimarsdóttir & Huan Song
Published in: British journal of cancer, Issue 9, 2022, Page(s) 1650-1659, ISSN 0007-0920
Publisher: Nature Publishing Group
DOI: 10.1038/s41416-022-01935-y

Depressive symptom trajectories among general population during the COVID-19 pandemic in Iceland: a prospective cohort study (2020–2023)

Author(s): Yue Wang, Arna Hauksdóttir, Edda Bjork Thordardottir, Fenfen Ge, Elísabet Unnur Gísladóttir, Jóhanna Jakobsdóttir, Kristjana Hrönn Ásbjörnsdóttir, Harpa Rúnarsdóttir, Anna Bára Unnarsdóttir, Ingibjörg Magnúsdóttir, Thorvardur Jon Love, Sigurdur Yngvi Kristinsson, Runolfur Palsson, Helga Zoega, Fang Fang, Gunnar Tómasson, Huan Song, Thor Aspelund, Unnur Valdimarsdottir
Published in: BMJ Public Health, Issue 2, 2024, Page(s) e001294, ISSN 2753-4294
Publisher: BMJ Public Health
DOI: 10.1136/bmjph-2024-001294

COVID-19 illness severity and 2-year prevalence of physical symptoms: an observational study in Iceland, Sweden, Norway and Denmark

Author(s): Qing Shen, Emily E. Joyce, Omid V. Ebrahimi, Maria Didriksen, Anikó Lovik, Karen Sól Sævarsdóttir, Ingibjörg Magnúsdóttir, Dorte Helenius Mikkelsen, Anna Bára Unnarsdóttir, Arna Hauksdóttir, Asle Hoffart, Anna K. Kähler, Edda Björk Thórdardóttir, Elías Eythórsson, Emma M. Frans, Gunnar Tómasson, Helga Ask, Hrönn Hardardóttir, Jóhanna Jakobsdóttir, Kelli Lehto, Li Lu, Ole A. An
Published in: The Lancet Regional Health - Europe, Issue 35, 2023, Page(s) 100756, ISSN 2666-7762
Publisher: Elsevier
DOI: 10.1016/j.lanepe.2023.100756

Elevated symptoms of depression and anxiety among family members and friends of critically ill COVID-19 patients

Author(s): Lovik, A.; González-Hijón, J.; , Hoffart, A.; Fawns-Ritchie, C.; Magnúsdóttir, I.; Lu, L.; Unnarsdóttir Bára, A.; Kähler, A. K.; Campbell, A.; Hauksdóttir, A.; Chourpiliadis, C.; McCartney, D.L.; Thordardóttir E.B.; Joyce, E.E.; Frans E.M.; Jakobsdóttir, J.; Trogstad, L.; Andreassen, O.A., Magnus, P.; Johnson, S.U.; Sullivan, P.F.; Aspelund, T.; Porteous, D.J.; Ask, H.; Ebrahimi, O.V.; V
Published in: The Lancret Regional Health, Issue 2, 2023, ISSN 2666-7762
Publisher: Lancet

Lifetime exposure to violence and other life stressors and hair cortisol concentration in women

Author(s): Rebekka Lynch, Thor Aspelund, Matthías Kormáksson, Mario H. Flores-Torres, Arna Hauksdóttir, Filip K. Arnberg, Martín Lajous, Clemens Kirschbaum & Unnur Valdimarsdóttir
Published in: The International Journal on the Biology of Stress, Issue 25, 2022, Page(s) 48-56, ISSN 1025-3890
Publisher: Taylor & Francis
DOI: 10.1080/10253890.2021.2011204

Genetic propensities for verbal and spatial ability have opposite effects on body mass index and risk of schizophrenia

Author(s): Gudrun A. Jonsdottir, Gudmundur Einarsson, Gudmar Thorleifsson, Sigurdur H. Magnusson, Arni F. Gunnarsson, Michael L. Frigge, Rosa S. Gisladottir, Unnur Unnsteinsdottir, Bjarni Gunnarsson, G. Bragi Walters, Valgerdur Steinthorsdottir, Anna Helgadottir, Ingileif Jonsdottir, Thorsteinn Gislason, Haraldur S. Thorsteinsson, Engilbert Sigurdsson, Magnus Haraldsson, Emil L. Sigurdsson, Ragnar Bjarnason,
Published in: Intelligence, Issue 88, 2021, Page(s) 101565, ISSN 0160-2896
Publisher: Elsevier BV
DOI: 10.1016/j.intell.2021.101565

Elevated symptoms of depression and anxiety among family members and friends of critically ill COVID-19 patients – an observational study of five cohorts across four countries

Author(s): Anikó Lovik, Juan González-Hijón, Asle Hoffart, Chloe Fawns-Ritchie, Ingibjörg Magnúsdóttir, Li Lu, Anna Bára Unnarsdóttir, Anna K. Kähler, Archie Campbell, Arna Hauksdóttir, Charilaos Chourpiliadis, Daniel L. McCartney, Edda Björk Thordardóttir, Emily E. Joyce, Emma M. Frans, Jóhanna Jakobsdóttir, Lill Trogstad, Ole A. Andreassen, Per Magnus, Sverre Urnes Johnson, Patrick F. Sulliva
Published in: The Lancet Regional Health - Europe, Issue 33, 2024, Page(s) 100733, ISSN 2666-7762
Publisher: Lancet
DOI: 10.1016/j.lanepe.2023.100733

Author(s): Fan Tian, Fang Fang, Qing Shen, Weimin Ye, Unnur A. Valdimarsdóttir, Huan Song
Published in: European Journal of Epidemiology, Issue 37, 2022, Page(s) 947-958, ISSN 0393-2990
Publisher: Kluwer Academic Publishers
DOI: 10.1007/s10654-022-00898-x

History of childhood maltreatment associated with hospitalization or death due to COVID-19: a cohort study

Author(s): Yue Wang, Fenfen Ge, Thor Aspelund, Helga Ask, Arna Hauksdóttir, Kejia Hu, Jóhanna Jakobsdóttir, Helga Zoega, Qing Shen, Heather C. Whalley, Ole Birger Vesterager Pedersen, Kelli Lehto, Ole A. Andreassen, Fang Fang, Huan Song, Unnur A. Valdimarsdóttir
Published in: BMC Medicine, Issue 22, 2024, ISSN 1741-7015
Publisher: BioMed Central
DOI: 10.1186/s12916-024-03399-8

Using Polygenic Hazard Scores to Predict Age at Onset of Alzheimer’s Disease in Nordic Populations

Author(s): Ehsan Motazedi, Weiqiu Cheng, Jesper Q. Thomassen, Oleksandr Frei, Arvid Rongve, Lavinia Athanasiu, Shahram Bahrami, Alexey Shadrin, Ingun Ulstein, Eystein Stordal, Anne Brækhus, Ingvild Saltvedt, Sigrid B. Sando, Kevin S. O’Connell, Guy Hindley, Dennis van der Meer, Sverre Bergh, Børge G. Nordestgaard, Anne Tybjærg-Hansen, Geir Bråthen, Lasse Pihlstrøm, Srdjan Djurovic, Ruth Frikke-Schmidt
Published in: Journal of Alzheimer’s Disease, Issue 88, 2025, Page(s) 1533-1544, ISSN 1387-2877
Publisher: IOS Press
DOI: 10.3233/jad-220174

The role of depression and antidepressant treatment in antihypertensive medication adherence and persistence: Utilising electronic health record data

Author(s): Hanna Maria Kariis, Silva Kasela, Tuuli Jürgenson, Aet Saar, Jana Lass, Kristi Krebs, Urmo Võsa, Elis Haan, Lili Milani, Kelli Lehto
Published in: Journal of Psychiatric Research, Issue 168, 2023, Page(s) 269-278, ISSN 0022-3956
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.jpsychires.2023.10.018

Boosting Schizophrenia Genetics by Utilizing Genetic Overlap With Brain Morphology

Author(s): Dennis van der Meer, Alexey A. Shadrin, Kevin O’Connell, Francesco Bettella, Srdjan Djurovic, Thomas Wolfers, Dag Alnæs, Ingrid Agartz, Olav B. Smeland, Ingrid Melle, Jennifer Monereo Sánchez, David E.J. Linden, Anders M. Dale, Lars T. Westlye, Ole A. Andreassen, Oleksandr Frei, Tobias Kaufmann
Published in: Biological psychiatry, Issue vol 92, no. 4, 2022, ISSN 0006-3223
Publisher: Elsevier BV
DOI: 10.1016/j.biopsych.2021.12.007

Depression, anxiety and brain volume after hearing loss and tinnitus: cohort study in the UK Biobank

Author(s): Xiaowan Chen, Kejia Hu, Huan Song, Li Yin, Magnus Kaijser, Tiril P. Gurholt, Ole A. Andreassen, Unnur Valdimarsdóttir, Fang Fang, Maoli Duan
Published in: BJPsych Open, Issue 10, 2024, ISSN 2056-4724
Publisher: Cambridge university Press
DOI: 10.1192/bjo.2023.634

Adipose tissue distribution from body MRI is associated with cross-sectional and longitudinal brain age in adults

Author(s): Dani Beck, Ann-Marie G de Lange, Dag Alnæs, Ivan I Maximov, Mads L Pedersen, Olof Dahlqvist Leinhard, Jennifer Linge, Rozalyn Simon, Geneviève Richard, Kristine M Ulrichsen, Erlend S Dørum, Knut K Kolskår, Anne-Marthe Sanders, Adriano Winterton, Tiril P Gurholt, Tobias Kaufmann, Nils Eiel Steen, Jan Egil Nordvik, Ole A Andreassen, Lars T Westlye
Published in: NeuroImage: Clinical, 2022, ISSN 2213-1582
Publisher: Elsevier BV
DOI: 10.1016/j.nicl.2022.102949

Cardiometabolic risk factors associated with brain age and accelerated brain ageing

Author(s): Dani Beck, Ann‐Marie G. de Lange, Mads L. Pedersen, Dag Alnæs, Ivan I. Maximov, Irene Voldsbekk, Geneviève Richard, Anne‐Marthe Sanders, Kristine M. Ulrichsen, Erlend S. Dørum, Knut K. Kolskår, Einar A. Høgestøl, Nils Eiel Steen, Srdjan Djurovic, Ole A. Andreassen, Jan E. Nordvik, Tobias Kaufmann, Lars T. Westlye
Published in: Human Brain Mapping, Issue 43, 2023, Page(s) 700-720, ISSN 1065-9471
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/hbm.25680

Views on sharing mental health data for research purposes: qualitative analysis of interviews with people with mental illness

Author(s): Emily Watson, Sue Fletcher-Watson, Elizabeth Joy Kirkham
Published in: BMC Medical Ethics, Issue 24, 2023, ISSN 1472-6939
Publisher: BioMed Central
DOI: 10.1186/s12910-023-00961-6

Trans-ancestry genome-wide study of depression identifies 697 associations implicating cell types and pharmacotherapies

Author(s): Mark J. Adams, Fabian Streit, Xiangrui Meng, Swapnil Awasthi, Brett N. Adey, Karmel W. Choi, V. Kartik Chundru, Jonathan R.I. Coleman, Bart Ferwerda, Jerome C. Foo, Zachary F. Gerring, Olga Giannakopoulou, Priya Gupta, Alisha S.M. Hall, Arvid Harder, David M. Howard, Christopher Hübel, Alex S.F. Kwong, Daniel F. Levey, Brittany L. Mitchell, Guiyan Ni, Vanessa K. Ota, Oliver Pain, Gita A. Pathak,
Published in: Cell, Issue 188, 2025, Page(s) 640-652.e9, ISSN 0092-8674
Publisher: Cell Press
DOI: 10.1016/j.cell.2024.12.002

The oxytocin signalling gene pathway contributes to the association between loneliness and cardiometabolic health

Author(s): Adriano Winterton, Francesco Bettella, Dani Beck, Tiril P. Gurholt, Nils Eiel Steen, Linn Rødevand, Lars T. Westlye, Ole A. Andreassen, Daniel S. Quintana
Published in: Psychoneuroendocrinology, 2022, ISSN 0306-4530
Publisher: Pergamon Press
DOI: 10.1016/j.psyneuen.2022.105875

Genomics yields biological and phenotypic insights into bipolar disorder

Author(s): Kevin S. O’Connell, Maria Koromina, Tracey van der Veen, Toni Boltz, Friederike S. David, Jessica Mei Kay Yang, Keng-Han Lin, Xin Wang, Jonathan R. I. Coleman, Brittany L. Mitchell, Caroline C. McGrouther, Aaditya V. Rangan, Penelope A. Lind, Elise Koch, Arvid Harder, Nadine Parker, Jaroslav Bendl, Kristina Adorjan, Esben Agerbo, Diego Albani, Silvia Alemany, Ney Alliey-Rodriguez, Thomas D. Als,
Published in: Nature, 2025, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-024-08468-9

The Effect of School Bullying on Pupils' Perceived Stress and Wellbeing During the Covid-19 Pandemic:A Longitudinal Study

Author(s): Elizabeth J. Kirkham; C. F. Huggins; Fawns-Ritchie C
Published in: Journal of Child & Adolescent Trauma , pp. 1-8 . https://doi.org/10.1007/s40653-022-00509-7, Issue 18, 2022, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1007/s40653-022-00509-7

Association of stress-related disorders with subsequent risk of all-cause and cause-specific mortality: A population-based and sibling-controlled cohort study

Author(s): Fan Tian, Qing Shen, Yihan Hu, Weimin Ye, Unnur A. Valdimarsdóttir, Huan Song, Fang Fang
Published in: The Lancet Regional Health - Europe, Issue 18, 2022, ISSN 2666-7762
Publisher: Elsevier
DOI: 10.1016/j.lanepe.2022.100402

A family study of symbolic learning and synaptic plasticity in autism spectrum disorder

Author(s): Granerud G, Elvsåshagen T, Arntzen E, Juhasz K, Emilsen NM, Sønderby IE, Nærland T, Malt EA
Published in: Frontiers in Human Neuroscience, 2022, ISSN 1662-5161
Publisher: Frontiers Research Foundation
DOI: 10.3389/fnhum.2022.950922

Replicating extensive brain structural heterogeneity in individuals with schizophrenia and bipolar disorder

Author(s): Thomas Wolfers; Thomas Wolfers; Thomas Wolfers; Jaroslav Rokicki; Jaroslav Rokicki; Dag Alnæs; Dag Alnæs; Pierre Berthet; Pierre Berthet; Ingrid Agartz; Seyed Mostafa Kia; Tobias Kaufmann; Mariam Zabihi; Torgeir Moberget; Torgeir Moberget; Ingrid Melle; Christian F. Beckmann; Ole A. Andreassen; Ole A. Andreassen; Andre F. Marquand; Andre F. Marquand; Lars T. Westlye; Lars T. Westlye
Published in: Human Brain Mapping, Issue 25, 2021, ISSN 1065-9471
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/hbm.25386

Extensive brain structural heterogeneity in individuals with schizophrenia and bipolar disorder

Author(s): Wolfers, Thomas; Rokicki, Jaroslav; Alnaes, Dag; Agartz, Ingrid; Kia, Seyed Mostafa; Kaufmann, Tobias; Zabihi, Mariam; Moberget, Torgeir; Melle, Ingrid; Beckmann, Christian F; Andreassen, Ole A; Marquand, Andre F; Westlye, Lars T
Published in: HBM, Issue 23, 2021, ISSN 1065-9471
Publisher: John Wiley & Sons Inc.
DOI: 10.1101/2020.05.08.20095091

1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans

Author(s): Ida E. Sønderby, Dennis van der Meer, Clara Moreau, Tobias Kaufmann, G. Bragi Walters, Maria Ellegaard, Abdel Abdellaoui, David Ames, Katrin Amunts, Micael Andersson, Nicola J. Armstrong, Manon Bernard, Nicholas B. Blackburn, John Blangero, Dorret I. Boomsma, Henry Brodaty, Rachel M. Brouwer, Robin Bülow, Rune Bøen, Wiepke Cahn, Vince D. Calhoun, Svenja Caspers, Christopher R. K. Ching, Sven Ci
Published in: Translational Psychiatry, Issue 11/1, 2021, ISSN 2158-3188
Publisher: Nature Publishing Group
DOI: 10.1038/s41398-021-01213-0

Adverse muscle composition predicts all-cause mortality in the UK Biobank imaging study.

Author(s): Jennifer Linge; Mikael Petersson; Mikael Forsgren; Arun J. Sanyal; Olof Dahlqvist Leinhard
Published in: Journal of Cachexia, Sarcopenia and Muscle, Vol 12, Iss 6, Pp 1513-1526 (2021), Issue 16, 2021, ISSN 2190-5991
Publisher: Springer Verlag
DOI: 10.1002/jcsm.12834

Bio-psycho-social factors’ associations with brain age: a large-scale UK Biobank diffusion study of 35,749 participants

Author(s): Max Korbmacher, Tiril P. Gurholt, Ann-Marie G. de Lange, Dennis van der Meer, Dani Beck, Eli Eikefjord, Arvid Lundervold, Ole A. Andreassen, Lars T. Westlye, Ivan I. Maximov
Published in: Frontiers in Psychology, Issue 14, 2023, ISSN 1664-1078
Publisher: Frontiers Research Foundation
DOI: 10.3389/fpsyg.2023.1117732

Psychiatric disorders and subsequent risk of cardiovascular disease: a longitudinal matched cohort study across three countries

Author(s): Qing Shen, Dorte Helenius Mikkelsen, Laura Birgit Luitva, Huan Song, Silva Kasela, Thor Aspelund, Jacob Bergstedt, Yi Lu, Patrick F. Sullivan, Weimin Ye, Katja Fall, Per Tornvall, Yudi Pawitan, Ole A. Andreassen, Alfonso Buil, Lili Milani, Fang Fang, Unnur Valdimarsdóttir
Published in: eClinicalMedicine, Issue 61, 2023, Page(s) 102063, ISSN 2589-5370
Publisher: The Lancet
DOI: 10.1016/j.eclinm.2023.102063

Shared genetic loci between depression and cardiometabolic traits

Author(s): Kristin Torgersen, Zillur Rahman, Shahram Bahrami, Guy Frederick Lanyon Hindley, Nadine Parker, Oleksandr Frei, Alexey Shadrin, Kevin S. O’Connell, Martin Tesli, Olav B. Smeland, John Munkhaugen, Srdjan Djurovic, Toril Dammen, Ole A. Andreassen
Published in: PLOS Genetics, Issue 18, 2022, Page(s) e1010161, ISSN 1553-7404
Publisher: Open Access publisher
DOI: 10.1371/journal.pgen.1010161

Shared genetic architecture between mental health and the brain functional connectome in the UK Biobank

Author(s): Daniel Roelfs, Oleksandr Frei, Dennis van der Meer, Elleke Tissink, Alexey Shadrin, Dag Alnaes, Ole A. Andreassen, Lars T. Westlye, Tobias Kaufmann
Published in: BMC Psychiatry, Issue 23, 2023, ISSN 1471-244X
Publisher: BioMed Central
DOI: 10.1186/s12888-023-04905-7

Incidence Trajectories of Psychiatric Disorders After Assault, Injury, and Bereavement

Author(s): Yufeng Chen, Qing Shen, Paul Lichtenstein, Jaimie L. Gradus, Filip K. Arnberg, Henrik Larsson, Brian M. D’Onofrio, Fang Fang, Huan Song, Unnur A. Valdimarsdottir
Published in: JAMA Psychiatry, Issue 81, 2024, Page(s) 374, ISSN 2168-622X
Publisher: American Medical Association
DOI: 10.1001/jamapsychiatry.2023.5156

Genetic Association Between Schizophrenia and Cortical Brain Surface Area and Thickness

Author(s): Weiqiu Cheng, Oleksandr Frei, Dennis van der Meer, Yunpeng Wang, Kevin S. O’Connell, Yunhan Chu, Shahram Bahrami, Alexey A. Shadrin, Dag Alnæs, Guy F. L. Hindley, Aihua Lin, Naz Karadag, Chun-Chieh Fan, Lars T. Westlye, Tobias Kaufmann, Espen Molden, Anders M. Dale, Srdjan Djurovic, Olav B. Smeland, Ole A. Andreassen
Published in: JAMA Psychiatry, Issue 78, 2021, Page(s) 1020, ISSN 2168-622X
Publisher: American Medical Association
DOI: 10.1001/jamapsychiatry.2021.1435

COGEDAP: A COmprehensive GEnomic Data Analysis Platform

Author(s): Bayram Cevdet Akdeniz, Oleksandr Frei, Espen Hagen, Tahir Tekin Filiz, Sandeep Karthikeyan, Joelle Pasman, Andreas Jangmo, Jacob Bergsted, John R. Shorter, Richard Zetterberg, Joeri Meijsen, Ida Elken Sonderby, Alfonso Buil, Martin Tesli, Yi Lu, Patrick Sullivan, Ole Andreassen, Eivind Hovig
Published in: Arxiv, 2022
Publisher: Cornell University
DOI: 10.48550/arxiv.2212.14103

Pleiotropic and sex-specific genetic architecture of circulating metabolic markers

Author(s): Dennis van der Meer, Zillur Rahman, Aigar Ottas, Pravesh Parekh, Gleda Kutrolli, Sara Stinson, Maria Koromina, Jaroslav Rokicki, Ida Sonderby, Nadine Parker, Markos Tesfaye, Guy Hindley, Linn Rodevand, Elise Koch, Nils Steen, Jens Berg, Kevin O'Connell, Olav Smeland, Oleksandr Frei, Anders Dale, Srdjan Djurovic, Kelli Lehto, Maris Alver, Lili Milani, Alexey Shadrin, Ole Andreassen
Published in: 2024, ISSN 2692-8205
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2024.07.30.24311254

Efficient meta-analysis of multivariate genome-wide association studies with Meta-MOSTest

Author(s): Aihua Lin, Alexey Shadrin, Dennis van der Meer, Guy Hindley, Weiqiu Cheng, Ida Elken Sønderby, Shahram Bahrami, Kevin S O’Connell, Zillur Rahman, Nadine Parker, Olav B Smeland, Chun C. Fan, Dominic Holland, Anders M Dale, Ole A Andreassen, Oleksandr Frei
Published in: 2022
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2022.08.18.504383

The Norwegian Mother, Father, and Child cohort study (MoBa) genotyping data resource: MoBaPsychGen pipeline v.1

Author(s): Elizabeth C. Corfield, Oleksandr Frei, Alexey A. Shadrin, Zillur Rahman, Aihua Lin, Lavinia Athanasiu, Bayram Cevdet Akdeniz, Laurie Hannigan, Robyn E. Wootton, Chloe Austerberry, Amanda Hughes, Martin Tesli, Lars T. Westlye, Hreinn Stefánsson, Kári Stefánsson, Pål R. Njølstad, Per Magnus, Neil M. Davies, Vivek Appadurai, Gibran Hemani, Eivind Hovig, Tetyana Zayats, Helga Ask, Ted Reichbo
Published in: bioRxiv, 2022
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2022.06.23.496289

Finemap-MiXeR: A variational Bayesian approach for genetic finemapping

Author(s): Bayram Cevdet Akdeniz, Oleksandr Frei, Alexey Shadrin, Dmitry Vetrov, Dmitry Kropotov, Eivind Hovig, Ole A. Andreassen, Anders M. Dale
Published in: Biorxiv, 2023
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2022.11.30.518509

Acute COVID-19 severity and mental health morbidity trajectories in patient populations of six nations: an observational study

Author(s): Magnúsdóttir et al
Published in: The Lancet Public Health, 2022, ISSN 2468-2667
Publisher: [Oxford] : Elsevier, Ltd., [2016]-
DOI: 10.1016/s2468-2667(22)00042-1

Better treatment response in people with obsessive-compulsive disorder is associated with more use of a planning-focused coping style

Author(s): Elizabeth Kirkham, Yintao Cao, Martyna Król
Published in: Open Research Europe, Issue 4, 2024, Page(s) 57, ISSN 2732-5121
Publisher: https://open-research-europe.ec.europa.eu/articles/4-57
DOI: 10.12688/openreseurope.17056.1

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