Implementation of personalised risk prediction and prevention of sudden cardiac death after myocardial infarction

Project Information

PROFID

Grant agreement ID: 847999

DOI

10.3030/847999

Project closed

EC signature date 13 December 2019

Start date 1 January 2020

End date 31 March 2026

Funded under

• SOCIETAL CHALLENGES - Health, demographic change and well-being

Total cost

€ 23 118 156,64

EU contribution

€ 19 884 569,75

Coordinated by

CHARITE - UNIVERSITAETSMEDIZIN BERLIN
Germany

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Websites, patent fillings, videos etc. (2)

Website
Clinical support tool for cardiologists

Open Research Data Pilot (1)

Data Management Plan

Publications

Non-peer reviewed articles (1)

The PROFID project

Author(s): Nikolaos Dagres, Niels Peek, Christophe Leclercq, Gerhard Hindricks
Published in: European Heart Journal, Issue 41/39, 2020, Page(s) 3781-3782, ISSN 0195-668X
Publisher: Oxford University Press
DOI: 10.1093/eurheartj/ehaa645

Peer reviewed articles (8)

How can non-inferiority studies with mortality end points be ethically justified?

Author(s): Dick Willems, Hanno Tan, Nikolaos Dagres, Marieke A R Bak
Published in: Journal of Medical Ethics, 2025, Page(s) jme-2024-110517, ISSN 0306-6800
Publisher: BMJ Publishing Group
DOI: 10.1136/jme-2024-110517

Sudden cardiac death after myocardial infarction: individual participant data from pooled cohorts

Author(s): Niels Peek, Gerhard Hindricks, Artur Akbarov, Jan G P Tijssen, David A Jenkins, Zoher Kapacee, Le Mai Parkes, Rob J van der Geest, Enrico Longato, Daniel Sprague, Youssef Taleb, Marcus Ong, Christopher A Miller, Alireza Sepehri Shamloo, Christine Albert, Petra Barthel, Serge Boveda, Frieder Braunschweig, Jens Brock Johansen, Nancy Cook, Christian de Chillou, Petra Elders, Jonas Faxén, Tim Friede,
Published in: European Heart Journal, Issue 45, 2024, Page(s) 4616-4626, ISSN 0195-668X
Publisher: Oxford University Press
DOI: 10.1093/eurheartj/ehae326

Ethical issues in two parallel trials of personalised criteria for implantation of implantable cardioverter defibrillators for primary prevention: the PROFID project—a position paper

Author(s): Dick Willems, Marieke Bak, Hanno Tan, Georg Lindinger, Ayca Kocar, Alireza Seperhi Shamloo, Georg Schmidt, Gerhard Hindricks, Nikolaos Dagres
Published in: Open Heart, Issue 8/2, 2021, Page(s) e001686, ISSN 2053-3624
Publisher: BMJ Open Heart
DOI: 10.1136/openhrt-2021-001686

How can we assess the risk for sudden cardiac death to decide for primary prophylactic implantable cardioverter-defibrillator in patients with heart failure in 2022?

Author(s): Jens Cosedis Nielsen, Nikolaos Dagres
Published in: EP Europace, Issue Volume 24, Issue 8, August 2022, 2022, Page(s) 1199-1200, ISSN 1099-5129
Publisher: Oxford University Press
DOI: 10.1093/europace/euac061

An update on the PROFID Project 2025

Author(s): Nikolaos Dagres, Bela Merkely, Gerhard Hindricks
Published in: European Heart Journal, Issue 47, 2026, Page(s) 660-661, ISSN 0195-668X
Publisher: Oxford University Press
DOI: 10.1093/eurheartj/ehaf845

PRevention of sudden cardiac death aFter myocardial infarction by defibrillator implantation: Design and rationale of the PROFID EHRA randomized clinical trial

Author(s): Nikolaos Dagres, Chris P Gale, Ramesh Nadarajah, Serge Boveda, Jose Luis Merino, Jens Cosedis Nielsen, Paulus Kirchhof, Valentina Kutyifa, Miloš Táborský, Holger Thiele, Jan G.P. Tijssen, Atul Verma, Tom De Potter, Frieder Braunschweig, Béla Merkely, Philipp Sommer, Kevin Vernooy, Mahmoud Suleiman, Helmut Pürerfellner, Gerhard Hindricks
Published in: American Heart Journal, Issue 291, 2026, Page(s) 37-43, ISSN 0002-8703
Publisher: Mosby Inc.
DOI: 10.1016/j.ahj.2025.07.071

Healthcare professionals’ perspectives on artificial intelligence in patient care: a systematic review of hindering and facilitating factors on different levels

Author(s): Dennis Henzler, Sebastian Schmidt, Ayca Koçar, Sophie Herdegen, Georg L. Lindinger, Menno T. Maris, Marieke A. R. Bak, Dick L. Willems, Hanno L. Tan, Michael Lauerer, Eckhard Nagel, Gerhard Hindricks, Nikolaos Dagres, Magdalena J. Konopka
Published in: BMC Health Services Research, Issue 25, 2025, ISSN 1472-6963
Publisher: BioMed Central
DOI: 10.1186/s12913-025-12664-2

Economic evaluation protocol for the PRevention Of sudden cardiac death aFter myocardial Infarction by Defibrillator implantation: the PROFID EHRA trial

Author(s): Yirui Qian, Carlos Rojas Roque, Beth Woods, Cynthia P Iglesias Urrutia, Vijay S Gc, Maria Gur Arie, Daniela Fischer, Nikolaos Dagres, Gerhard Hindricks, Andrea Manca
Published in: BMJ Open, Issue 16, 2026, Page(s) e097495, ISSN 2044-6055
Publisher: BMJ Publishing Group
DOI: 10.1136/bmjopen-2024-097495

Other (1)

Development and Validation of a Multivariable Risk Prediction Model for Sudden Cardiac Death after Myocardial Infarction (PROFID Risk Model): Study Rationale, Design and Protocol

Author(s): Glen P. Martin, Gerhard Hindricks, Artur Akbarov, Zoher Kapacee, Le Mai Parkes, Golnoosh Motamedi-Ghahfarokhi, Stephanie Ng, Daniel Sprague, Youssef Taleb, Marcus Ong, Enrico Longato, Christopher A. Miller, Alireza Sepehri Shamloo, Christine Albert, Petra Barthel, Serge Boveda, Frieder Braunschweig, Jens Brock Johansen, Nancy Cook, Christian de Chillou, Petra J.M. Elders, Jonas Faxen, Tim Friede,
Published in: medRxiv, Issue n/a, 2021
Publisher: medRxiv
DOI: 10.1101/2021.07.12.21260002