A new perspective on the metabolic pathway to neuronal dysfunction: Using organs on a chip to elucidate the role of the brain microvasculature

Project Information

SweetBrain

Grant agreement ID: 851765

DOI

10.3030/851765

EC signature date 2 October 2019

Start date 1 September 2020

End date 30 November 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 487 438,00

EU contribution

€ 1 487 438,00

Coordinated by

TEL AVIV UNIVERSITY
Israel

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (13)

Multi‐Sensor Origami Platform: A Customizable System for Obtaining Spatiotemporally Precise Functional Readouts in 3D Models

Author(s): Noam Rahav, Denise Marrero, Adi Soffer, Emma Glickman, Megane Beldjilali‐Labro, Yakey Yaffe, Keshet Tadmor, Yael Leichtmann‐Bardoogo, Uri Ashery, Ben M. Maoz
Published in: Advanced Science, Issue 11, 2024, ISSN 2198-3844
Publisher: wiley publishing
DOI: 10.1002/advs.202305555

Super-Resolution-Chip: an in-vitro platform that enables super-resolution microscopy of co-cultures and 3D systems

Author(s): Ofir Sade, Ronja Boneberg, Yifat Weiss, Megane Beldjilali-Labro, Yael Leichtmann-Bardoogo, Itay Talpir, Irit Gottfried, Uri Ashery, Rossana Rauti, Ben M. Maoz
Published in: Biomedical Optics Express, Issue 14, 2024, Page(s) 5223, ISSN 2156-7085
Publisher: The Optical Society
DOI: 10.1364/boe.498038

Inducing Mechanical Stimuli to Tissues Grown on a Magnetic Gel Allows Deconvoluting the Forces Leading to Traumatic Brain Injury

Author(s): Luise Schlotterose, Megane Beldjilali-Labro, Mario Hagel, Moran Yadid, Carina Flaxer, Eli Flaxer, A. Ronny Barnea, Kirsten Hattermann, Esther Shohami, Yael Leichtmann-Bardoogo, Ben M. Maoz
Published in: Neurotrauma Reports, Issue 4, 2023, Page(s) 560-572, ISSN 2689-288X
Publisher: Mary Ann Liebert, Inc.
DOI: 10.1089/neur.2023.0026

Biology and Models of the Blood–Brain Barrie

Author(s): Cynthia Hajal, Baptiste Le Roi, Roger D. Kamm, and Ben M. Maoz
Published in: Annual Review of Biomedical Engineering, 2021, ISSN 1936-1335
Publisher: Annual Reviews A Nonprofit Scientific Publisher
DOI: 10.1146/annurev-bioeng-082120-042814

Traumatic Brain Injury in a Well: A Modular Three-Dimensional Printed Tool for Inducing Traumatic Brain Injury In vitro

Author(s): Luise Schlotterose, Megane Beldjilali-Labro, Gaya Schneider, Ofir Vardi, Kirsten Hattermann, Uzi Even, Esther Shohami, Herman D. Haustein, Yael Leichtmann-Bardoogo, and Ben M. M
Published in: Neurotrauma Reports, Issue Volume: 4 Issue 1: April 20, 2023, 2023, Page(s) 255-266, ISSN 2689-288X
Publisher: Mary Ann Liebert, Inc.
DOI: 10.1089/neur.2022.0072

Effect of SARS-CoV-2 proteins on vascular permeability.

Author(s): Rossana Rauti; Meishar Shahoha; Yael Leichtmann-Bardoogo; Rami Nasser; Eyal Paz; Rina Tamir; Victoria Miller; Tal Babich; Kfir Shaked; Avner Ehrlich; Konstantinos Ioannidis; Yaakov Nahmias; Roded Sharan; Uri Ashery; Ben M. Maoz
Published in: eLife, Issue 1, 2021, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.69314

Transforming a well into a chip: A modular 3D-printed microfluidic chip.

Author(s): Rossana Rauti; Adi Ess; Baptiste Le Roi; Yevgeniy Kreinin; Mark Epshtein; Netanel Korin; Ben M. Maoz
Published in: APL Bioengineering, Issue 1, 2021, ISSN 2473-2877
Publisher: AIP Publishing LLC
DOI: 10.1063/5.0039366

Spatial Trans-Epithelial Electrical Resistance (S-TEER) Integrated in Organs-on-Chips

Author(s): Noa Renous; Mark Dan Kiri; Ronny Aharon Barnea; Rossana Rauti; Yael Leichtamnn-Bardoogo; Ben M. Maoz
Published in: Lab on a Chip, Issue 1, 2022, ISSN 1473-0197
Publisher: Royal Society of Chemistry
DOI: 10.1039/d1lc00789k

Current state of the art and future directions for implantable sensors in medical technology: Clinical needs and engineering challenges

Author(s): David Yogev, Tomer Goldberg, Amir Arami, Shai Tejman-Yarden, Thomas E. Winkler, Ben M. Maoz
Published in: APL Bioengineering, Issue 7, 2023, ISSN 2473-2877
Publisher: AIP publishing
DOI: 10.1063/5.0152290

Insight on Bacterial Newborn Meningitis Using a Neurovascular-Unit-on-a-Chip

Author(s): Rossana Rauti, Sharon Navok, Dvora Biran, Keshet Tadmor, Yael Leichtmann-Bardoogo, Eliora Z. Ron, Ben M. Maoz
Published in: Microbiology Spectrum, Issue 11, 2023, ISSN 2165-0497
Publisher: American Society for Microbiology
DOI: 10.1128/spectrum.01233-23

Technology-based approaches toward a better understanding of neuro-coagulation in brain homeostasis

Author(s): Ben M. Maoz, Maria Asplund, Nicola Maggio & Andreas Vlachos
Published in: Cell and Tissue Research, 2022, ISSN 1432-0878
Publisher: Springer Nature
DOI: 10.1007/s00441-021-03560-2

Brain-on-a-Chip: Characterizing the next generation of advanced in vitro platforms for modeling the central nervous system

Author(s): Ben M. Maoz
Published in: APL Bioengineering, Issue 3, 2021, ISSN 2473-2877
Publisher: AIP Publishing LLC
DOI: 10.1063/5.0055812

Brain‐Targeted Liposomes Loaded with Monoclonal Antibodies Reduce Alpha‐Synuclein Aggregation and Improve Behavioral Symptoms in Parkinson's Disease

Author(s): Mor Sela, Maria Poley, Patricia Mora‐Raimundo, Shaked Kagan, Aviram Avital, Maya Kaduri, Gal Chen, Omer Adir, Adi Rozencweig, Yfat Weiss, Ofir Sade, Yael Leichtmann‐Bardoogo, Lilach Simchi, Shlomit Aga‐Mizrachi, Batia Bell, Yoel Yeretz‐Peretz, Aviv Zaid Or, Ashwani Choudhary, Idan Rosh, Diogo Cordeiro, Stav Cohen‐Adiv, Yevgeny Berdichevsky, Anas Odeh, Jeny Shklover, Janna Shainsky‐Roit
Published in: Advanced Materials, Issue 35, 2024, ISSN 0935-9648
Publisher: United Nations Industrial Developement Organization
DOI: 10.1002/adma.202304654