Gut-Brain Communication in Metabolic Control

Project Information

GuMeCo

Grant agreement ID: 851778

DOI

10.3030/851778

Project closed

EC signature date 4 October 2019

Start date 1 March 2020

End date 28 February 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 500 000,00

EU contribution

€ 1 500 000,00

Coordinated by

MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
Germany

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (9)

Integrative neurocircuits that control metabolism and food intake

Author(s): Jens C. Brüning, Henning Fenselau
Published in: Science, Issue 381, 2024, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.abl7398

NPY-mediated synaptic plasticity in the extended amygdala prioritizes feeding during starvation

Author(s): Stephan Dodt, Noah V. Widdershooven, Marie-Luise Dreisow, Lisa Weiher, Lukas Steuernagel, F. Thomas Wunderlich, Jens C. Brüning, Henning Fenselau
Published in: Nature Communications, Issue 15, 2024, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-024-49766-0

Gut-brain communication by distinct sensory neurons differently controls feeding and glucose metabolism

Author(s): Diba Borgmann, Elisa Ciglieri, Nasim Biglari, Claus Brandt, Anna Lena Cremer, Heiko Backes, Marc Tittgemeyer, F. Thomas Wunderlich, Jens C. Brüning, Henning Fenselau
Published in: Cell Metabolism, Issue 33/7, 2021, Page(s) 1466-1482.e7, ISSN 1550-4131
Publisher: Cell Press
DOI: 10.1016/j.cmet.2021.05.002

Vagal pathways for systemic regulation of glucose metabolism

Author(s): Diba Borgmann, Henning Fenselau
Published in: Seminars in Cell & Developmental Biology, Issue 156, 2024, Page(s) 244-252, ISSN 1084-9521
Publisher: Academic Press
DOI: 10.1016/j.semcdb.2023.07.010

Technical Note: Modulation of fMRI brainstem responses by transcutaneous vagus nerve stimulation

Author(s): Diba Borgmann, Lionel Rigoux, Bojana Kuzmanovic, Sharmili Edwin Thanarajah, Thomas F. Münte, Henning Fenselau, Marc Tittgemeyer
Published in: NeuroImage, Issue 244, 2021, Page(s) 118566, ISSN 1053-8119
Publisher: Academic Press
DOI: 10.1016/j.neuroimage.2021.118566

Neural gut-to-brain communication for postprandial control of satiation and glucose metabolism

Author(s): Leonie Cabot, Juliet Erlenbeck-Dinkelmann, Henning Fenselau
Published in: Journal of Endocrinology, Issue 258, 2023, ISSN 0022-0795
Publisher: Society for Endocrinology
DOI: 10.1530/joe-22-0320

Thalamic opioids from POMC satiety neurons switch on sugar appetite

Author(s): Marielle Minère, Hannah Wilhelms, Bojana Kuzmanovic, Sofia Lundh, Debora Fusca, Alina Claßen, Stav Shtiglitz, Yael Prilutski, Itay Talpir, Lin Tian, Brigitte Kieffer, Jon Davis, Peter Kloppenburg, Marc Tittgemeyer, Yoav Livneh, Henning Fenselau
Published in: Science, Issue 387, 2025, Page(s) 750-758, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.adp1510

GABAergic disinhibition from the BNST to PNOCARC neurons promotes HFD-induced hyperphagia

Author(s): Tamara Sotelo-Hitschfeld, Marielle Minère, Paul Klemm, Diba Borgmann, Daria Wnuk-Lipinski, Alexander Jais, Xianglian Jia, Svenja Corneliussen, Peter Kloppenburg, Henning Fenselau, Jens Claus Brüning
Published in: Cell Reports, Issue 43, 2024, Page(s) 114343, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2024.114343

Advanced neurobiological tools to interrogate metabolism

Author(s): Paul Nicholas Mirabella, Henning Fenselau
Published in: Nature Reviews Endocrinology, Issue 19, 2023, Page(s) 639-654, ISSN 1759-5029
Publisher: Nature Publishing Group
DOI: 10.1038/s41574-023-00885-6