Ubiquitin Chains in Viral Infections

Project Information

CHUbVi

Grant agreement ID: 856581

DOI

10.3030/856581

EC signature date 9 December 2019

Start date 1 March 2020

End date 28 February 2026

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 7 649 848,00

EU contribution

€ 7 649 848,00

Coordinated by

FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION
Switzerland

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (13)

Site-Specific Protein Ubiquitylation Using an Engineered, Chimeric E1 Activating Enzyme and E2 SUMO Conjugating Enzyme Ubc9

Author(s): Akimoto, G.; Fernandes, A. P.; Bode, J. W
Published in: ACS central science, 2022, Page(s) 275–281, ISSN 2374-7951
Publisher: ACS Publications
DOI: 10.1021/acscentsci.1c01490

Chemoproteomik-basierende Zielprotein-Dekonvolution und Erstellung der Selektivitätsprofile von Histone Deacetylase Inhibitoren

Author(s): Lechner, Severin
Published in: Nature Communications, Issue 3, 2023, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-023-39151-8

Atomic Tailoring of Ubiquitin Side Chains Influences E2-Mediated Ubiquitin Chain Formation

Author(s): Haewon Song; Toshiki Mikami; Sohei Majima; Jeffrey Bode
Published in: Crossref, Issue 5, 2024, ISSN 0018-019X
Publisher: Verlag Helvetica Chimica Acta
DOI: 10.26434/chemrxiv-2023-26rl0

Liquid Biomolecular Condensates and Viral Lifecycles: Review and Perspectives

Author(s): Etibor TA, Yamauchi Y, Amorim MJ
Published in: Viruses, 2021, ISSN 1999-4915
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v13030366

A quantitative mechanism for HDAC6-mediated virus uncoating helps to predict Influenza A infectivity.

Author(s): Arctibasova A, Wang L, Anchisi S, Yamauchi Y, Schmolke M, Matthias P & Stelling
Published in: Cell reports, 2023, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2023.113558

Enhanced SARS-CoV-2 entry via UPR-dependent AMPK-related kinase NUAK2

Author(s): Vibhu Prasad 1 , Berati Cerikan 2 , Yannick Stahl 2 , Katja Kopp 2 , Vera Magg 2 , Nelson Acosta-Rivero 2 , Heeyoung Kim 2 , Katja Klein 3 , Charlotta Funaya 4 , Uta Haselmann 2 , Mirko Cortese 2 , Florian Heigwer 5 , Josephine Bageritz 6 , David Bitto 3 , Saruul Jargalsaikhan 2 , Christopher Neufeldt 2 , Felix Pahmeier 2 , Michael Boutros 6 , Yohei Yamauchi 7 , Alessia Ruggieri
Published in: Mol Cell, 2023, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2023.06.020

HDAC6/aggresome processing pathway importance for inflammasome formation is context dependent

Author(s): Wang L, Unterreiner A, Kapetanovic R, Aslani S, Xiong Y, Donovan KA, Farady CJ, Fischer ES, Bornancin F and Matthias P
Published in: JOURNAL OF BIOLOGICAL CHEMISTRY, 2024, ISSN 0021-9258
Publisher: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1016/j.jbc.2024.105638

How Influenza Virus Uses Host Cell Pathways during Uncoating

Author(s): Etori Aguiar Moreira, Yohei Yamauchi, Patrick Matthias
Published in: Cells, Issue 10/7, 2021, Page(s) 1722, ISSN 2073-4409
Publisher: Cells
DOI: 10.3390/cells10071722

The α-dystroglycan N-terminus is a broad-spectrum antiviral agent against SARS-CoV-2 and enveloped viruses

Author(s): Maria Giulia Bigotti; Katja Klein; Esther S. Gan; Maria Anastasina; Simon Andersson; Olli Vapalahti; Pekka Katajisto; Maximilian Erdmann; Andrew D. Davidson; Sarah J. Butcher; Ian Collinson; Eng Eong Ooi; Giuseppe Balistreri; Andrea Brancaccio; Yohei Yamauchi
Published in: Bigotti , M G , Klein , K , Gan , E S , Anastasina , M , Andersson , S , Vapalahti , O , Katajisto , P , Erdmann , M , Davidson , A D , Butcher , S J , Collinson , I , Ooi , E E , Balistreri , G , Brancaccio , A & Yamauchi , Y 2024 , ' The α-dystroglycan N-terminus is a broad-spectrum antiviral agent against SARS-CoV-2 and enveloped viruses ' , Antiviral Research , vol. 224 , 105837 . https://doi, Issue 2, 2024, ISSN 0166-3542
Publisher: Elsevier BV
DOI: 10.1101/2023.11.06.565781

Neuropilin-1 is a host factor for SARS-CoV-2 infection.

Author(s): James L. Daly; Boris Simonetti; Katja Klein; Kai-En Chen; Maia Kavanagh Williamson; Carlos Antón-Plágaro; Deborah K. Shoemark; Lorena Simón-Gracia; Michael Bauer; Reka Hollandi; Urs F. Greber; Peter Horvath; Peter Horvath; Richard B. Sessions; Ari Helenius; Julian A. Hiscox; Julian A. Hiscox; Tambet Teesalu; David A. Matthews; Andrew D. Davidson; Brett M. Collins; Peter J. Cullen; Yohei Yamauch
Published in: Science, Issue 2, 2020, Page(s) 861-865, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.abd3072

A widespread viral entry mechanism: The C-end Rule motif–neuropilin receptor interaction

Author(s): Balistreri G, Yamauchi Y, Teesalu T. A widespread viral entry mechanism: The C-end Rule motif-neuropilin receptor interaction.
Published in: Proceedings of the National Academy of Sciences (PNAS), 2021, ISSN 1091-6490
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2112457118

ESCPE-1 Mediates Retrograde Endosomal Sorting of the SARS-CoV-2 Host Factor Neuropilin-1

Author(s): Simonetti B, Daly JL, Simón-Gracia L, Klein K, Weeratunga S, Antón-Plágaro C, Tobi A, Hodgson L, Lewis P, Heesom KJ, Shoemark DK, Davidson AD, Collins BM, Teesalu T, Yamauchi Y, Cullen PJ
Published in: Proceedings of the National Academy of Sciences (PNAS), 2022, ISSN 1091-6490
Publisher: National Academy of Sciences
DOI: 10.1101/2022.01.20.477115

Biocompatible lysine protecting groups for the chemoenzymatic synthesis of K48/K63 heterotypic and branched ubiquitin chains

Author(s): Toshiki Mikami; Sohei Majima; Haewon Song; Jeffrey W. Bode
Published in: ACS Central Science, Vol 9, Iss 8, Pp 1633-1641 (2023), Issue 3, 2023, ISSN 2374-7943
Publisher: ACS Publication
DOI: 10.26434/chemrxiv-2023-hlk3f

Other (1)

Disrupting the HDAC6-ubiquitin interaction impairs infection by influenza and Zika virus and cellular stress pathways

Author(s): Wang L, Moreira EA, Kempf G, Miyake Y, Oliveira Esteves BI, Fahmi A, Schaefer JV, Dreier B, Yamauchi Y, Alves MP, Plückthun A and Matthias P
Published in: 2022, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2022.110736