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CORDIS - EU research results
CORDIS

Superconducting Mass Spectrometry and Molecule Analysis

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Iterated SNWD design, specification, fabrication, delivery (opens in new window)

Iterated SNWD design specification fabrication delivery

Optimized ion steering and Chip cleaning in cryochamber (opens in new window)

Optimized ion steering and Chip cleaning in cryochamber

SNWD sensitivity to internal molecular energy (opens in new window)

Report on SNWD sensitivity to internal molecular energy

Validation 5: Peptides with green PCTs synthesized and validated (opens in new window)
Validation 3: peptides/proteins detected by 8-pixel SNWA prototype (opens in new window)

Validation 3 peptidesproteins detected by 8pixel SNWA prototype

Validation 9: Preparation of a mass selected neutral protein beam (opens in new window)

Validation 9 Preparation of a mass selected neutral protein beam

128-pixel array prototype, shipped Vienna (opens in new window)

128pixel packaged array prototype shipped to Vienna

Report on reliability in UHV, thermal cycling, molecular irradiation (opens in new window)

Report on reliability in UHV thermal cycling molecular irradiation

Strategies for increasing density and collimation of neutral protein beams (opens in new window)
Validation 2: Optimized SNWD tested with proteins (opens in new window)

Validation 2 Optimized SNWD tested with proteins

Validation 11: SNWD assisted detection of absorption in neutral macromolecules (opens in new window)

Validation 11 SNWD assisted detection of absorption in neutral macromolecules

Validation 6: Peptides with blue PCTs synthesized and validated (opens in new window)

Validation 6 Peptides with blue PCTs synthesized and validated

Complete mass spectrometer design: selectors, optics zones, cryogenic chamber (opens in new window)
8-pixel packaged array prototype, shipped to Vienna (opens in new window)

8pixel packaged array prototype shipped to Vienna

Validation 8: SNWD detection of singly-charged mass selected 100 kDa proteins (opens in new window)

Validation 8 SNWD detection of singlycharged mass selected 100 kDa proteins

Validation 10: SNWD assisted detection of absorption in biopolymer ions (opens in new window)

Validation 10 SNWD assisted detection of absorption in biopolymer ions

Publications

A 0.32 × 0.12 mm^2 Cryogenic BiCMOS 0.1–8.8 GHz Low Noise Amplifier Achieving 4 K Noise Temperature for SNWD Readout (opens in new window)

Author(s): Y. Peng, J. Benserhir, M. Castaneda, A. Fognini, C. Bruschini and E. Charbon
Published in: IEEE Transactions on Microwave Theory and Techniques, 2024, ISSN 1557-9670
Publisher: IEEE
DOI: 10.1109/tmtt.2024.3354828

Highly sensitive single-molecule detection in slow protein ion beams (opens in new window)

Author(s): M. Strauß, A. Shayeghi, M.F.X. Mauser, P. Geyer, T. Kostersitz, J. Salapa, O. Dobrovolskiy, S. Daly, J. Commandeur, Y. Hua, V. Köhler, M. Mayor, J. Benserhir, C. Bruschini, E. Charbon, M. Castaneda, M. Gevers, R. Gourgues, N. Kalhor, A. Fognini, and M. Arndt
Published in: Science Advances, Issue 9, 2023, Page(s) 48, ISSN 2375-2548
Publisher: American Society Association for the Advancement of Science
DOI: 10.1126/sciadv.adj2801

Giving the Green Light to Photochemical Uncaging of Large Biomolecules in High Vacuum (opens in new window)

Author(s): Yong Hua, Marcel Strauss, Sergey Fisher, Martin F. X. Mauser, Pierre Manchet, Martina Smacchia, Philipp Geyer, Armin Shayeghi, Michael Pfeffer, Tim Henri Eggenweiler, Steven Daly, Jan Commandeur, Marcel Mayor, Markus Arndt, Tomáš Šolomek, and Valentin Köhler
Published in: JACS, 2023, ISSN 2691-3704
Publisher: ACS Publications
DOI: 10.1021/jacsau.3c00351

Neutralization of an Oxytocin Derivative by 355 nm Photocleavage in High Vacuum (opens in new window)

Author(s): Yong Hua, Daniel Häussinger, Marcel Mayor, Valentin Köhler, Marcel Strauss, Martin F. X. Mauser, Tim Kostersitz, Philipp Geyer, Markus Arndt
Published in: Helvetica Chimica Acta, Issue 108, 2025, ISSN 0018-019X
Publisher: Verlag Helvetica Chimica Acta
DOI: 10.1002/hlca.202400167

Superconducting Nanowire Detection of Neutral Atoms and Molecules via Their Internal and Kinetic Energy in the eV Range (opens in new window)

Author(s): M. Strauß, R. Gourgues, M. F. X. Mauser, L. Kulman, M. Castaneda, A. Fognini, A. Shayeghi, P. Geyer, M. Arndt
Published in: Advanced Physics Research, Issue 4, 2025, ISSN 2751-1200
Publisher: Wiley
DOI: 10.1002/apxr.202400133

Giving the green light to photochemical uncaging of large biomolecules in high vacuum (opens in new window)

Author(s): Yong Hua, Marcel Strauss, Sergey Fisher, Martin F. X. Mauser , Pierre Manchet, Martina Smacchia, Philipp Geyer, Armin Shayeghi, Michael Pfeffer, Tim Henri Eggenweiler, Steven Daly, Jan Commandeur, Marcel Mayor, Markus Arndt, Tomáš Šolomek, Valentin Köhler
Published in: 2023
Publisher: -
DOI: 10.26434/chemrxiv-2023-mgqg3

Click, Lock & Dye: a chromogenic handle for selective cysteine modification

Author(s): Yong Hua, Zhi Zou, Alessandro Prescimone,Thomas R. Ward, Marcel Mayor, Valentin Köhler
Published in: 2023
Publisher: ChemRxiv

Superconducting quantum detectors and single photon charge control for mass spectrometry (opens in new window)

Author(s): Marcel Strauß, Armin Shayeghi, Martin Mauser, Pierre Manchet, Martina Smacchia, Julia Salapa, Tim Kostersitz, Philipp Geyer, Steven Daly, Jan Commandeur, Yong Hua, Alfredo Di Silvestro, Marcel Mayor, Valentin Köhler, Jad Benserhir, Claudio Bruschini, Edoardo Charbon, Mario Castaneda, Monique Gevers, Ronan Gourgues, Nima Kalhor, Andreas Fognini, Markus Arndt
Published in: Proceedings of SPIE - Proceedings Volume 12447, Quantum Sensing, Imaging, and Precision Metrology; 124470I (2023), 2023, Page(s) 124470I-1 to 124470I-7
Publisher: Proceedings of SPIE
DOI: 10.1117/12.2657258

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